eurRs 9 19. MEDICATIA APARATULUL LOCOMOTOR DEPANIFItStEXPLICATIL Antacoiifa cp ‘Climacterium = menopauzd Coliveerza = exzimd car xe gist fn snap din festa nervosa erro, Prin acianea el de hidrolisiaaceticoline libre menting un el brain activates acest neurtransoitor, CGirara» ori vegetal putenicd altri dinte-an amen de ales care ationeaz anv ple erminale motors din mish, pls mse culatra strat, Moareasurvine rapid dato paralsie mugcilcrespratort. ‘Oxcognccd»formarea de et ono. Onto = rexorbja de ent onos i ct mot pcs tinal notre = spa epsom culard= formatlune alls din buon terminal ol sxoelr (cee sid Inervjia more sarcolema fret muscular, La acest nive nfl nervos provoac elberares meatal chimi - aceticolira~ cae delangeuz on Tracie muscular a ores {herwll, care linge articulate t mugs ina”. Nata a tmp st se- ‘hele valvlrela or insufciené mitral, senond mitral ec) Vesa mc spr vata = proce ei ince eh ‘aja esteasiguat de un vetltor automat, sc{ionat electric a care bon {ste conc pinto send oo- (su naz) trabea. La acest apr pot a 9 aici mtr ve tr, volun i presines ar ind 19.1, MEDICATIA ANTIREUMATISMALA 4181.1 ANTIINELAMATOARE NESTEROIDIENE (AINS)[M 01 A) lst de medianente ce fice ae din mare up estlgsic pie care predomintacjunesitinfanstoct i antreamatn Cathe 2 "bch 184. Etc lor farmacodinamlc el dente eosin elo (COX-1 COX), cee ce reaizcad cine annamstoare prin dimainuaren proceso ifanator cu dferte local acuneantreumati avind elect bene electvasupea inflame dea seul fest conjunc cru apart structs aeaieg ~ sje anlgetil pin sciereaemporard«dareir legate de alam: ~ étaneanermict deourecscotebuie a scddere obey ‘cian anagreganc plachetar, stilts impotia tomboudlor eel sar expunind la singer persoanle care waza de acate mudiancne lowe magi ndeungat, ~ fect de ria « mucous’ gesice,patind dice pin le eparia ulcer er tie tocol (de inhbare a conreylor urine), Accrteacjun fete sunt dfertecantenatate de aun antinfamatorla| tulsa plas Is wale dinte acest medicament e adage propre. dup cum se va vedes ma jos, Idea bol reumatsnale (polar reaatoi, euratomal artclar scat); nel colagenoes tendnite; tnosinort;entenite; lombalgis diese daze articular muscular; migene;angine oie; rombolleit; kemore- lai Preenio antafamatoute nesteroidene wilt a mod curt * Antinlamatoareneteroldiene (AINS) neelective = Asidul aetalec (spring) este el ri spin p mal cunoscut AINS. Ave aclu aninflametoue, atreumatcs,analenc, antped de anagegant plachetar. Se pevint sub form de comprinat. Ar ls ‘muliple: in reumatologle petra tratamentelreamtiaml rl ax, polartrt:reumatode ol manifesto inflamatoe article arti, aa i) ou muscle ite, edt cere) nl an aio Pot prefliastombonlr crn int moc inin respirator sezniere fbi; fn trombaze rei in unl sindrome 5 mmnee ene, ise nop tle Pn ts nedenen tar us pari ree eee eer ee nate Petes aaa oo Farmaco Acs sell poat Pre Roem leavin co eee ee Toei cu dene canting pse deh apaiawa le ps fu dodenal entra eve eaclor adverse efter pe tac pli nepal es inet Cpt (or i we coneanins a iskevaleeple) Se pose soci counpansament tity Deaton st ‘Continue fein gatos (gt peeeeaeren aa ere te; suck; aneni hemollc prin deft de hicon-6fov-ddrogeoes aie ? hoc fox cbr = Defect pretint sbnamerone demir comer [> abe 191 tn forn de compre Sate deer gure, apne ls ‘err relunp supontonre gle penta in. ilar in tote me feck bolle umatismae i pdomtacn cape vsaposoereare propre gins ssa toe oe NS etnies ryscepinate tfc penned eee fave on det lad propnl td bun teres igativt"Re print sub forma de comprinste fmt, caps djs 2 ae Papntnae pet cop eid og lg deal one re a Sou Brunet apd in col efor nee rt See re hag ore comprare mae caréan un conn dbl de aad ag aude preprtlune a pk asco 208) Fr oe ana ab form ecompimue ines ple et ontoar lene tot un deriv! aacdl onions ae atau nvrlln tt erat lacs Preis se simittrenape calor : amt Elden) ace pane iar xan ws net San Te lara eurateie eponda skort SP dase tonal de caprue,comprimate, pulbere pentru sue ore suPon: BOE cin, Produce reac ede gee importate: 2m Charifica c= Aniinfamatowe neserudiene (AINS) (M01 A] Sa) Pe a earner | renal ‘Aci tllesamic | a tet Esbnenciam este” SS Sees eee fas ey inate apt f= ee See ee Sar | cman ROE rig a a cee es SS a = tee reir ee acer ae ee eicery sem oa pe | eae oe ee — ener i vaca conpeae Sat) —_—_—_——" m> Tenosicam, comprimatecaprule are fect asemsndtonre plroxicamul, Nisan amie ta rel gt one pattern oem penie Imnosspesie nc. 18 4 Uncle medlcamentecitotaice(citostatce) ‘Acffonealinhblnd mecnisinee\mne (de formare x nticorplor auto snicorplr) Administatein ace sop, doze sunt mk ma mil dec atng ‘nde losse in bal neoplaice (canceoase) ~ Metotrezat(Antiflan"sdeinstrt per os sau. ipl reuma- toi gars prviasich. Penta detalii Citostatice in cap 17 « Derivaiiaidulai aminoraliciie Sunt wiz tn gastroeaterologe, ca ntinfamatoar intestinal (in col- ta tleeross, boals Crohn, ea eponala, dei cotonopst) ~ Sallaslarind (Salazopyrin) indicat in pliant euratoid spond Ia anchlozant. Administra oral 19.2, SUBSTANTE MIORELAXANTE PERIFERICE SURARIZANTE DE SINTEZA) (M03 A] ‘Acct btn vsti cu entail genere in intervene ch -rurgicale de amploare, realizind o relaxare musculari total, ceea ce failiteasd equa cul operator Coaizatl deste lone pa Hort cfectulatactlcline la nivel plicil motori(snapsa calinegic neuroms- alad) nmogcl staf prooctnd purine ecatr. le resin un ric oteotal mens deoarece dupe paraines succor fone dgedor spol pt tncs erat fal mi mero l= iin ~Girl duclnd la mon i pers ep tore Singur mjc de evar acest cient eens pres 5 EoYentilafiel mecanice (suport ventilator), sub care interventa chirurgicalé poat decare i peck cu condi nnionah (emninoapeet re erupt fant vise) a perenel oper. stdout rupee uae cura d stn: ‘Ccqrarzatels depois, ete stent clint dn plac matre prodacind sd ineclubitih ud cten wana Zulnerys motor (glen de acne) mas nalpanterepeore a Satstaneeantiainesteranic (Mos?) trortins acumen ceehey pote fel depen tran Din gape pcan Teton (eacllcolng, yetienn’ cance 2. caramel anidpoarnane cre few pe recs cline shel plc notr, boctndst compet faa ce and: Saree tntclneseresceinpiicadisctvares celine etna teaacsel anced aces coraantdor antdeplnane: Dao trol fn pre: plains (Faxed) ravacutum (aca) pce tin (Peal, ocuronun Cameron) wearin scan ais tam (acon), Andel wpentEaT scr shea car oooigns (iwi cae seciak stop (penira pevnres ctor moat cecal pele 19.3. MEDICATIA OSTEOPOROZEI SIA ALTOR AFECTIUNI OSOASE DECALCIFIANTE (M05) Osteoporoza este refer a structuri osoae, localiza sau generaliats fl fact oru iri a-ji modifica forms, devine fal casant, ind expus It Fractur.(Trebuie deosebité de osteomalacte, tn care se produce un deficit de sineralare dh odepunere de oft cle reusing ‘mode eeormabil). Eun stcoporoe srl, oteaporora polices, ‘osteoporoza din bosla Cushing in coticoterpiaprelunglt, orteoporora di fnsulicenga renald cronich Ivestgeia care confirms evalocazt stsoporors tte osteodensitometria, unde ca etalon de comprise ulizeestdensistes ‘mineral ocoss a adululul tod coping esas falendronat de sodiu; Fosamax") et indicat in os scopes pvtlipecterum ge dp isbliae peng Adminae pc bancone(Bondrona’) tnt a popes ris esl dia mouse apstela aria alge Amie Ev 276 ~ Acide rsedrone (isedronat de sod; hibuzes osteoclast cae produc reli Inducostcogenea. React adverse: allure ale, dare) Administra orl. Actone" actionens pian pin actvare osteatlate cre iestv (gas ure abl # ALTE MEDICAMENTS IMPOTRIVA OSTEOPOROZEL ~"Fluorura de sods (Onin) administare orl = Raneatl de stronfa (Osseo) administrare oral = Kalonifen (Evista) esieun modhlnioe select indicaTn proba osteoporzela ferme in prelimcterue, ~ Caleitonina (Tonocalcia’) ese un harmon secret de cule pari cule din tid are rol In metaboiemal cal: seade reson osu sf, economisind conjnutl osselor In caleia sefsid cel pasa fet ‘ipoclcemian). Indic steoporo postinaceriam ces din mobi ze prelungt; stil dehiperalcemie, metssze ooae ale tumor magne ‘Adminstare: aerosol din spray. an pin sts spc — in PE. recor esos,20. ANESTEZICE $I ANALGEZICE Demiryu stexeticar Anal = eden cre veal ners cna Anes ban cope tempor en ont el rin contact prs den (inner eat de ncn prose Gloss Cap. 9 MEDICATIA APARATULUILOcoMeTOR 20.1. ANESTEZICE GENERALE [N 01 4] ese enrol naar cone, pce ae prin eed, runldelndurin ee tancea ion reahe side consent. imp e cai piomonntc che nee feaeampe puindstproper nad depen deste ane ae sateen TA nail ucla un oper cece meget vin automat dana popes Refer aus pastas ethic devin ol ign er potion ler! ene Fea write ee de sum sper taco pane a eee dp, lee repr ple TA Sn normale: pple opr a mie Caner igo nal mar ade fa de som til profed cn opin pet fecal pero: repaa,pll TA sin neal onal muse cet, popes lag nro reeset martes le ee re eater tre, pl eect dara pirat totes Gb ocr ‘Soh pop mie fad wt cr och cae vi ole np met: nial rept cn lace male TA pb pus inperesp lob oc fetid persistent mascara das ate segment: Monrose ae stp pin pre cdorapeaere mm 3 primi temporar durerea prin ajiune la i ateadurerasi ci Tabu 20.1, Anestece generale 101A Dapicalade | Gropcht] De sinew | “Ta | mnttaeag.| Seas | sura| Gera | Sa |= aie ae on — _|isreiiaeret srainaie | ota |i Joe prin eho SUBSTANTE MIORELXAN- ‘TE PERIFERICE (crarznt dessert incp. 5 2”20.2, ANESTEZICE LOCALE [N 01 B) Anctericle lose sont apie uneor cup este sper rm tempts scnsibltatesdurerost a zo0a unde tars llr forme de sensi il, sensltatealaprestune car ue ee receptor pentru durere ponte f plate). Ensta sree e contact (de suprafi) prin sopitee sopra (deerempls inte por dfn fh focal “ ‘um hid anestezic vo ~ prin injectrenanestencas in mat multe puncte din egunea ee Puncte din regimes saps uni 2% sca spray pentru anesteiedesuprafsh. Exit conbinain anne eee 5 i a en ann ee ec eee arenes pri nfilrares neva sensi care servet o on i tat. 203. ANAIGEZICE OPIOIDE N24] (oaturle sau de sine) sctioneat Ia nivel strat ner lin interme receporlor specie ee sut receptor ono [aL Ace reeeptartcotespund pepldelor plelde endogee, care repent geil lologi. Opaceee determin - altri de combateres dure ~ 4 280 [Osea [nara cnt — ea map Be [Bate moe anaes it fect secundaeimporante fran mace moi ele ‘al, prec i eomene de smacodepener (ade) Din opi ase ea din cape de ma lb pre soma bao) “sexe seed seal at ei an ens circ inane Cl actives saga exe moron arene ogni =) et ‘sage mld ae codebase propia Aa dcr podo satrap ete 9 eset Dera toteopacet pet noma a are smal ek Pent fel pal, gerade oman: inset poh fe edminars lee cen rep sealers in rch nt celal seve id peel une pete deve cu nee Fulda get dersen cuese ele ema Mari ileus wen sepia scruniturvd un ft nlc ped foe pie. Farr eden pee int psec as hsa ‘Tabelul 20.3. Relaia ate calea de administrare a morfine, tingerea peak-ulul yi durataefectului anageric (Gale mimes | Angers peal ces Dine) mer! toa pletoaictmasins) | eect oneie (Gee Tet Ss Sipe lem pae mings $ esa ars nee) or fnkctse. Si nia cm ne 305 eine Soe iy. nie So (ups Taketone CK etal, modlca) ‘miocardic; edem pulmonar a turer In cancer. Conrsndiai opt sob bitrin|: abdomen scat; astm broogi;hipertrote de pros, Farmacotexclgie: poate produce deprimatea resin, vrstus tpn fishipotensiune arterial ma ales farmacodependente inca anil (> Cap. 33 - DROGURL, STUPEFIANTE, NARCOTICE ~ Codein,un alkaloid natural in ope ca etune rine pa nhiares relexall de tue, nd lizat cant Dearece eect analgec ete ste utlzat in acest cop numa in combina cu alte analgerice: Napedoren? = code fosforicé + paracetamol (comprimate): Hferalaa"endeine» pare tumel+ codeng faerie (comprimateeervescene) ~ Petiina (Minigin) (fol petra sdrnnistrare sm, lent exe un opioid de sitet cu efetanalgenc mails deci morn (hat x ssn de refering), totug cu larga Intrebuinjave in chirurgle ortopedie ober Indicaitn special pentr tratamente gi der de curt rat Pst podvce farmacodependen, dar nude gravtetca morfinomanici ~ Fentanyl (Dusogesic") se pretn gia fl injectable caste ans lermic(pistire), avin absorbiecutaatd lent dar contin. Ente india in durercronce, unde tebe ssigrat un sport continu siconstant de analyeze ~ Pentazocin (Fete) (compete fol pest smc pe- enh) est unprepared sine fect analgesic Sab eit or fine find un agonist partial. Nu necesireeticu tbr sc, cl doer ree cares reine. Tram ae, sponitoare, foe penta dol (Teamal"; Urgendo!(comprimse,supoitoare, 1x) ete dat in doer de intensitate mee sau deo severtate mode- tm mu 20.4, ANALGEZICE-ANTIPIRETICE (N 02] Medcamenele in aceat cash un fect anagem sh de pt- ‘ee da se bucurk de o foarte larg rispndiregutlizae curent. Nucreesah_ 282 ) pot lot acpi devel mica jt ma pce prescrip edie pen eer da amack Femmachenns et ol tein pein dace reumatsnaleyportimumatec de spars eet (eck, mide etorse hat); wot tanentigicadinee a, 4k sl find ance ~in sin vote ale sell ee ae ‘eb eile, daver scat dese Gee mal even iat [3 Tuell 2 ~ Acid acti eprint) It vb dete forme maple Cap. 21 ~ MEDICATIA UNOR BOLL [NEUROLOGICE). Are ins gun pene eect anaes spr duro ena pode herpes.ie acne snc g tama, Dea a Sa ae Sicteeerenecae| eta wes i per sacee 2 sae copra seni compet pn ee acm pes Norte pe = Soa Aes anil > ‘st emipami coupe fo ose tne vor rot ngs ite pees prod ten ttl + propincne ro pet apne Rana mp pe Ee penton ye et om mts eps ee eto [Gimtees pane saa ema abt acne smc cme) screen ice iy +1 esa ret ome sew yet er nai ford Jue wa a ears oe ite lame le fe onpomued le ean 20.5, PRODUSE IMPOTRIVA MIGRENET [62 c) Masson nom ceri prin cnet 1 Gemicane capa de a a Seah ee rs ce fll se ace dtr face rio lc oe dere rr degen ea detalles orcs niger satis oat eee ie Dintre medicamenteleanimigrnoase meni 2 Aleaoit din ergot ‘Actioneio Tn rina mlgrenos pri fecal or vasoconstrictor sopra ae loc endocranien. Sunt contraindcat ln arco i aliptare, Prodss neo Cofedl(drjeuri conjinind ergotamied = cote 4 Agoniq al rceporilor serotoninergic HT, -Aceytin acioneat selectvasupra receptor #17 inhibod proces de ‘asodiltaje intacranian8 cae ae loci rsa migrroua NU ast ose lactic namai cua in eis Sant containiatta HEA gt leion tenn ene Preparate disponibile: a = Suratriptan(mnigean”) —comprimate mate ~ Rizatriptan (Maxalt)-comprimate ~ Hletriptan (Relpax”) ~ compmate filma ~ Fromatrptan (Fromens") ~ comprinate fate # Medicamentedin else este nscppolacrevere clr igen) Aap, ca aca principal ee anders Admire on 1a eben ntdgmaie neds Bf ea cee ~ Propranolol este un foram. ness sed psepalle Andi TA tunel rim cardiac [3 Medieamenteetaritnie inca). ‘Administra oral. Flos es medicament profit ~ Verapamil exe un impos arlene dt fst Pentru prflalacrieor migrenoase [> Mesicament anaritmice nap. 9 Adoni ————— 4 Unelemedicameatecombinae din dass amalgeteaniireicrea1a ‘compostie acid acelialilic paracetamol cof po ffs ca att simp ingots dare din cur tir mipesose Pes Spo ble AiopesAntnaralg Calne tig Face Rama las 5