DRUGS TO BE AVOIDED BY CONGENITAL LONG QT PATIENTS
CredibleMeds® has reviewed all available evidence and has placed the following drugs in
Generic Name
Abarelix (PR)
Abiraterone (CR)
Aclarubicin (KR)
Albuterol (salbutamol) (SR)
Alfuzosin (PR)
Alimemazine (Trimeprazine)
(PR)
Amantadine (CR)
Amiodarone (KR)
Amisulpride (CR)
Amitriptyline (CR)
Amphetamine (Amfetamine)
(SR)
Amphotericin B (CR)
Amsacrine (Acridinyl
anisidide) (CR)
Anagrelide (KR)
Apalutamide (PR)
Apomorphine (PR)
Arformoterol (SR)
Aripiprazole (PR)
Arsenic trioxide (KR)
Artemether/Lumefantrine
(PR)
Artenimol/piperaquine (PR)
Asenapine (PR)
Astemizole (KR)
Atazanavir (CR)
Atomoxetine (PR)
Azithromycin (KR)
Bedaquiline (PR)
Bendamustine (PR)
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designated risk categories for their risk of causing torsades de pointes (TdP): Known Risk
of TdP (KR), Possible Risk of TdP (PR), Conditional Risk of TdP (CR) or Special Risk
(SR). The full description of these categories can be found on the CredibleMeds website.
We recommend that patients with Congenital Long QT Syndrome avoid use of these
medicines if at all possible or take them under close medical observation.
Brand Name Generic Name Brand Name Generic Name Brand Name
Plenaxis Bendroflumethiazide Cocaine (KR) Cocaine
Aprinox and others
(Bendrofluazide) (CR)
Zytiga and others Crizotinib (PR) Xalkori
Benperidol (PR) Anquil and others
Aclacin and others Cyamemazine
Tercian
Benzphetamine (SR) Didrex and others (Cyamepromazine) (PR)
Proventil and others
Bepridil (KR) Vascor Dabrafenib (PR) Tafinlar
Uroxatral
Betrixaban (PR) Bevyxxa Dasatinib (PR) Sprycel
Nedeltran and others
Bortezomib (PR) Velcade and others Degarelix (PR) Firmagon and others
Symmetrel and others Bosutinib (PR) Bosulif Delamanid (PR) Deltyba
Cordarone and others Buprenorphine (PR) Butrans and others Desipramine (PR) Pertofrane and others
Barhemsys and others Cabozantinib (PR) Cometriq Deutetrabenazine (PR) Austedo
Elavil (Discontinued 6/13) Capecitabine (PR) Xeloda Dexmedetomidine (PR) Precedex and others
and others
Carbetocin (PR) Pabal and others Dexmethylphenidate (SR) Focalin and others
Adderal-XR and others Ceritinib (PR) Zykadia Dextroamphetamine
Dexedrine and others
(Dexamfetamine) (SR)
Cesium Chloride (KR) Energy Catalyst
Fungilin and others
Dextromethorphan/Quinidine
Chloral hydrate (CR) Aquachloral and others Nuedexta
(PR)
Amsidine
Chloroquine (KR) Aralen
Diethylpropion (SR) Tenuate and others
Agrylin and others Chlorpromazine (KR) Thorazine and others
Diphenhydramine (CR) Benadryl and others
Erleada Chlorprothixene (KR) Truxal
Disopyramide (KR) Norpace
Apokyn and others Cilostazol (KR) Pletal
Dobutamine (SR) Dobutrex
Brovana Cimetidine (CR) Tagamet
Dofetilide (KR) Tikosyn
Abilify and others Ciprofloxacin (KR) Cipro and others
Dolasetron (PR) Anzemet
Trisenox Cisapride (KR) Propulsid
Domperidone (KR) Motilium and others
Citalopram (KR) Celexa and others
Coartem Donepezil (KR) Aricept
Clarithromycin (KR) Biaxin and others
Dopamine (SR) Intropine
Eurartesim
Clofazimine (PR) Lamprene
Doxepin (CR) Sinequan and others
Saphris and others
Clomipramine (CR) Anafranil
Dronedarone (KR) Multaq
Hismanal
Clotiapine (PR) Entumine
Droperidol (KR) Inapsine and others
Reyataz and others
Clozapine (PR) Clozaril and others
Droxidopa (SR) Northera
Strattera
Cobimetinib (PR) Cotellic
Efavirenz (PR) Sustiva
Zithromax and others
Eliglustat (PR) Cerdelga
Sirturo
Treanda and others
Generic Name Brand Name Generic Name Brand Name Generic Name Brand Name
Encorafenib (PR) Braftovi Hydrocodone - ER (PR) Hysinglaâ„¢ ER and others Lopinavir/Ritonavir (PR) Kaletra and others
Entrectinib (PR) Rozlytrek Hydroquinidine Lumateperone (PR) Caplyta
Serecor
(Dihydroquinidine) (KR)
Eperisone (CR) Myonal and others Lurasidone (PR) Latuda
Hydroxychloroquine (KR) Plaquenil and others
Ephedrine (SR) Rynatuss and others Maprotiline (PR) Ludiomil
Hydroxyzine (CR) Atarax and others
Epinephrine (Adrenaline) Meglumine antimoniate (KR) Glucantime
Primatene and others
(SR) Ibogaine (KR)
Melperone (PR) Bunil and others
Epirubicin (PR) Ellence and others Ibutilide (KR) Corvert
Memantine (PR) Namenda XR
Eribulin mesylate (PR) Halaven Iloperidone (PR) Fanapt and others
Mesoridazine (KR) Serentil
Erythromycin (KR) E.E.S. and others Imipramine (Melipramine)
Tofranil Metaproterenol (Orciprenaline)
(PR) Metaprel and others
Escitalopram (KR) Cipralex and others (SR)
Indacaterol (SR) Arcapta Neohaler and others
Esomeprazole (CR) Nexium and others Methadone (KR) Dolophine and others
Indapamide (CR) Lozol and others
Ezogabine (Retigabine) Methamphetamine
Potiga and others Desoxyn and others
(PR) Inotuzumab ozogamicin (PR) Besponsa (Metamfetamine) (SR)
Famotidine (CR) Pepcid and others Isoproterenol (SR) Medihaler-Iso and others Methylphenidate (SR) Ritalin and others
Felbamate (PR) Felbatol Isradipine (PR) Dynacirc Metoclopramide (CR) Reglan and others
Fenfluramine (SR) Fintepla Itraconazole (CR) Sporanox and others Metolazone (CR) Zytanix and others
Fenoterol (SR) Berotec and others Ivabradine (CR) Procoralan and others Metronidazole (CR) Flagyl
Fingolimod (PR) Gilenya Ivosidenib (PR) Tibsovo Mianserin (PR) Tolvon
Flecainide (KR) Tambocor and others Ketanserin (PR) Sufrexal Midodrine (SR) ProAmatine and others
Fluconazole (KR) Diflucan and others Ketoconazole (CR) Nizoral and others Midostaurin (PR) Rydapt
Fluorouracil (5-FU) (PR) Adrucil and others Lacidipine (PR) Lacipil and others Mifepristone (PR) Korlym and others
Fluoxetine (CR) Prozac and others Lansoprazole (CR) Prevacid and others Mirabegron (PR) Myrbetriq
Flupentixol (PR) Depixol and others Lapatinib (PR) Tykerb and others Mirtazapine (PR) Remeron
Fluticasone And Lefamulin (PR) Xenleta Moexipril/Hydrochlorothiazide
Advair and others Uniretic and others
Salmeterol (SR) (PR)
Lenvatinib (PR) Lenvima
Fluvoxamine (CR) Faverin and others Moxifloxacin (KR) Avelox and others
Leuprolide (Leuprorelin) (PR) Lupron and others
Formoterol (SR) Foradil and others Necitumumab (PR) Portrazza
Levalbuterol (Levsalbutamol)
Xopenex and others
Furosemide (frusemide) (SR) Nelfinavir (CR) Viracept
Lasix and others
(CR)
Levetiracetam (PR) Keppra Nicardipine (PR) Cardene
Galantamine (CR) Reminyl and others
Levmetamphetamine Nifekalant (KR) Shinbit
Sinu Inhaler and others
Garenoxacin (CR) Geninax (Levmetamfetamine) (SR)
Nilotinib (PR) Tasigna
Gatifloxacin (KR) Tequin Levofloxacin (KR) Levaquin and others
Norepinephrine (SR) Levophed
Gemifloxacin (PR) Factive Levomepromazine
Nosinan and others Norfloxacin (PR) Noroxin and others
(Methotrimeprazine) (KR)
Gilteritinib (PR) Xospata
Nortriptyline (PR) Pamelor and others
Levomethadone
Glasdegib (PR) Daurismo
(levamethadone) (PR) Nusinersen (PR) Spinraza
Granisetron (PR) Kytril and others
Levomethadyl acetate (KR) Orlaam Ofloxacin (PR) Floxin
Grepafloxacin (KR) Raxar
Levosulpiride (KR) Lesuride and others Olanzapine (CR) Zyprexa and others
Halofantrine (KR) Halfan
Lisdexamfetamine (SR) Vyvanse Oliceridine (PR) Olinvyk
Haloperidol (KR) Haldol and others
Lithium (PR) Eskalith and others Olodaterol (SR) Striverdi Respimat
Hydrochlorothiazide (CR) Apo-Hydro and others
Lofexidine (PR) Lucemyra
Loperamide (CR) Imodium

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 Generic Name
Omeprazole (CR)
Ondansetron (KR)
Osilodrostat (PR)
Osimertinib (PR)
Oxaliplatin (KR)
Oxymetazoline (SR)
Oxytocin (PR)
Ozanimod (PR)
Paliperidone (PR)
Palonosetron (PR)
Panobinostat (PR)
Pantoprazole (CR)
Papaverine HCl (Intra-
coronary) (KR)
Paroxetine (CR)
Pasireotide (PR)
Pazopanib (PR)
Pentamidine (KR)
Perflutren lipid microspheres
(PR)
Perphenazine (PR)
Phendimetrazine (SR)
Phentermine (SR)
Phenylephrine (SR)
Phenylpropanolamine (SR)
Pilsicainide (PR)
Pimavanserin (PR)
Pimozide (KR)
Pipamperone (PR)
Piperacillin/Tazobactam (CR)
Pitolisant (Tiprolisant) (PR)
Posaconazole (CR)
Pretomanid (PR)
Primaquine phosphate (PR)
Note: Medicines on this list are reviewed on an ongoing basis to assure
Probucol (KR) Lorelco
recommend checking the website
Procainamide (KR)
Disclaimer and Waiver: The information presented is intended solely for the purpose of providing general information about health-related matters. It is not intended for any other purpose,
including but not limited to medical advice and/or treatment, nor is it intended to substitute for the users relationships with their own health care providers. To that extent, by use of this website
and the information it contains, the user affirms the understanding of the purpose and releases AZCERT, Inc. from any claims arising out of his/her use of the website and its lists. The
absence of drugs from these lists should not be considered an indication that they are free of risk of QT prolongation or torsades de pointes. Many medicines have not been tested for this risk
in patients, especially those with congenital long QT syndrome.
Brand Name Generic Name Brand Name Generic Name Brand Name
Losec and others Promethazine (PR) Phenergan Tamoxifen (PR) Nolvadex and others
Zofran and others Propafenone (CR) Rythmol SR and others Tazemetostat (PR) Tazverik
Isturisa Propofol (KR) Diprivan and others Telaprevir (CR) Incivo and others
Tagrisso Prothipendyl (PR) Dominal and others Telavancin (PR) Vibativ
Eloxatin Pseudoephedrine (SR) PediaCare and others Telithromycin (PR) Ketek
Afrin and others Quetiapine (CR) Seroquel Terbutaline (SR) Brethine and others
Pitocin and others Quinidine (KR) Quinaglute and others Terfenadine (KR) Seldane
Zeposia Quinine sulfate (CR) Qualaquin and others Terlipressin (KR) Teripress and others
Invega and others Ranolazine (CR) Ranexa and others Terodiline (KR) Micturin and others
Aloxi Remimazolam (PR) Byfavo Tetrabenazine (PR) Nitoman and others
Farydak Ribociclib (PR) Kisqali Thioridazine (KR) Mellaril and others
Protonix and others Rilpivirine (PR) Edurant and others Tiapride (PR) Tiapridal and others
Risperidone (CR) Risperdal Tipiracil/Trifluridine (PR) Lonsurf
Ritodrine (SR) Yutopar Tizanidine (PR) Zanaflex and others
Paxil and others
Romidepsin (PR) Istodax Tolterodine (PR) Detrol and others
Signifor
Roxithromycin (KR) Rulide and others Toremifene (PR) Fareston
Votrient
Rucaparib (PR) Rubraca Torsemide (Torasemide)
Demadex and others
Pentam (CR)
Salmeterol (SR) Serevent and others
Tramadol (PR) Crispin and others
Definity and others Saquinavir (PR) Invirase(combo)
Trazodone (CR) Desyrel and others
Selpercatinib (PR) Retevmo
Trilafon and others
Trimipramine (PR) Surmontil and others
Sertindole (KR) Serdolect and others
Bontril and others
Tropisetron (PR) Navoban and others
Sertraline (CR) Zoloft and others
Adipex P and others
Valbenazine (PR) Ingrezza
Sevoflurane (KR) Ultane and others
Neosynephrine
Vandetanib (KR) Caprelsa
Sibutramine (SR) Meridia
Acutrim and others
Vardenafil (PR) Levitra
Siponimod (PR) Mayzent
Sunrythm
Vemurafenib (PR) Zelboraf
Solifenacin (CR) Vesicare
Nuplazid
Venlafaxine (PR) Effexor and others
Sorafenib (PR) Nexavar
Orap
Vilanterol/fluticasone furoate
Sotalol (KR) Betapace and others Breo Ellipta
Dipiperon and others (SR)
Sparfloxacin (KR) Zagam
Tazosyn and others Voriconazole (CR) VFend
Sulfamethoxazole and
Wakix Septra and others Vorinostat (PR) Zolinza
Trimethoprim (SR)
Noxafil and others Xylometazoline
Sulpiride (KR) Dogmatil and others Sinosil and others
(Xylomethazoline) (SR)
Sultopride (KR) Barnetil and others
Ziprasidone (CR) Geodon and others
that the
Sunitinib (PR)available evidence supports their continued placement on
Sutent this list.
Zotepine (PR)The list changesLosizopilon
regularlyand
and we
others
at crediblemeds.org for the most up-to-date
Tacrolimusinformation.
(PR) TherePrograf
may be andmany
others additional brand names that are not listed on this form.
Zuclopenthixol
Pronestyl and others Cisordinol and others
(Zuclopentixol) (PR)
Generated: March 15, 2021. List last revised: December 17, 2020