Professional Documents
Culture Documents
1997
All rights reserved
Printed in the United States of America
This manual and the software described herein are copyrighted with all rights reserved.
Under the copyright laws, this manual and the software may not be copied, in whole or in
part, without written consent of Gold Standard Multimedia Inc., except in the normal use
of the software or to make a back-up copy as specified in the software license agreement.
In no event will Gold Standard Multimedia Inc. be liable for direct, indirect, special,
incidental, or consequential damages resulting from any defect in the software or its
documentation, even if advised of the possibility of such damages.
Technical Support
E-Mail: Tech_Support@GSM.COM
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Table of Contents
I. Introduction
A. About Clinical Pharmacology
B. Content
1. Drug Information
2. User-Entered Information
C. Interface
1. Objects
2. Menubar
D. Program Organization
1. Lists of Standardized Terms
2. Levels
B. Content
The information in Clinical Pharmacology has been written specifi-
cally for this program, so the software and the information can be
“linked” as tightly as possible. However, there is also a philosophy
behind the information itself. Also, a distinction between the drug
information, which we provide, and the user-entered information,
which you provide, should be made.
1. Drug Information
Because a goal of this program is to save you time, we have
attempted to condense information about the drugs into mono-
graphs that are concise and clinically relevant. We believe you will
appreciate this approach as you face everyday clinical situations.
We hope that you will trust that the material included in these
monographs is indeed “important.” Because of this philosophy, we
have avoided prioritizing or ranking items, preferring to simply not
include the items of less significance, while providing a descriptive
paragraph for each included item, should you wish to know more.
When making a statement which could be regarded as not widely
known or accepted, we have included the reference from the
primary literature from which the statement was derived.
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our aim to provide accurate, timely information on every generic
preparation available in the US.
2. User-Entered Information
The drug information files we provide are “read-only,” meaning
that you cannot change that information within the program.
However, there are several types of information which you, the
user, provide. You enter this data into the program and can, of
course, change it as you like. Patient records, prescriptions, drug
utilization records, and the privileges you give to other users of the
program are examples. Accordingly, when we ship you an update
to the program, you will need to transfer this information to the
new version. We will constantly strive to keep this operation as
simple as possible (see Chapter II for more details).
Finally, you will probably notice that the information you enter is
closely linked to the drug information. For example, you select
medical conditions for a patient from indexes of indications and
contraindications found within the drug monographs. This enables
the program to utilize the user-entered information to the best
possible advantage.
C. Interface
The information is presented in a “point-and-click” interface, which
to programmers is known as an object-oriented environment. In
other words, the building blocks of the program are objects of
different types and appearances which you can point to and click
on to perform functions. You can also choose menu items and use
keyboard shortcuts from the menubar.
1. Objects
The most basic type of object is a window; in Clinical Pharmacology,
each type of information is presented in a unique window. There
can be several windows open at any time, but only the top window
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is active. Windows become smaller as they overlie other windows,
so the context in which they were brought up is preserved. Each
window may have many different screens, or “pages,” which
present different aspects of the same general class of information.
For example, each drug monograph has its own screen, but each is
displayed in the same Monographs window. Usually, a window
has a consistent graphical appearance, while the information
changes between screens.
2. Menubar
Clinical Pharmacology is designed to emphasize the use of buttons
and mouse clicks in order to maximize your time savings. How-
ever, the menubar is available, both to allow you to have other
applications open simultaneously and navigate between the
applications, and to provide you with several standard keyboard
shortcuts. The menus are introduced in Chapter II; individual
menu items are discussed throughout this manual.
To use the keyboard to access menu items, hold down the <Alt>
key while hitting a letter which is underlined on a menu item. This
will cause the appropriate menu item to be activated. This process
can be repeated to access cascading menus. For example, to exit the
program, hold down the <Alt> key and type “f” then “x.”
D. Program Organization
1. Lists of standardized terms
Much of the information in Clinical Pharmacology is in the form of
lists, which is of tremendous importance. Basically, each list is an
index to more information, which is usually accessed by clicking
twice on a specific item. In this way, you can pick out the informa-
tion you want in a very precise way. Hopefully, the program will
I-3
allow you to spend significantly less time searching for the “page”
or paragraph you need.
Many lists are marked off with special characters before each item.
These characters imply something about the items. Specifically, a
bullet (“Ω”) before an item designates it as a standardized term or
phrase within the program. All standardized terms are fully
indexed and cross-referenced throughout. An arrow (“œ”) signifies
a category of drugs or terms. The arrowed term is also itself a
standardized term. Squares (“˛”) designate medication entries
associated with a particular patient, prescription, or report. These
entries are standardized, too, and are indexed and cross-referenced
throughout the Patient Records section of the program.
2. Levels
Clinical Pharmacology is organized on four “levels.” These are the
Title, Index, Monographs/Patient Records, and More Information
levels, and are designed to present more detailed information as
you progress from Title to More Information.
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Chapter II. Getting Started
A. Installation
The program is supplied on either of two media—CD-ROM or 3.5"
diskettes. The software itself is identical in both formats. It requires
4 MB of memory, but prefers 8 MB or more. Approximately 45 MB
of storage is necessary to install the entire program onto a hard
disk. If you choose to run the program from the CD or over a
network, 6 MB of local hard disk space is used. Windows 3.1,
Windows NT, or Windows 95 is required.
1. CD-ROM
To install the CD-ROM version, first turn off any screen savers.
Windows 3.1: Insert the CD-ROM, and from the File menu of
Program Manager, select “Run.” Type “D:\SETUP.EXE” in the
command prompt (substituting the letter of your CD-ROM drive
for D: if necessary).
Windows 95 or NT: Insert the CD-ROM, and from the Start menu,
select “Run.” Type “D:\SETUP.EXE” in the command line prompt.
Alternatively, open the CD-ROM drive on your desktop, then
double-click on the “setup.exe” icon.
The installation program will start, and you will be prompted for
an installation directory (the default is C:\CPWIN). If you would
like to install to a different directory, type the name of the directory
in the box. Click “OK” to continue. NOTE: If you are updating, you
must install the program into the same directory as the previous
version.
II - 1
After the installation process is complete, a dialog box will be
displayed indicating successful installation, followed by the
README file, which you should read before proceeding. If you
have any problems during installation, please contact our Technical
Support department.
2. Diskettes
To install the diskette version, first turn off any screen savers.
Windows 3.1: Insert Disk 1, and from the File menu of Program
Manager, select “Run.” Type “A:\SETUP.EXE” in the command
prompt (substituting the letter of your floppy drive for A: if
necessary).
Windows 95 or NT: Insert Disk 1, and from the Start menu, select
“Run.” Type “A:\SETUP.EXE” in the command line prompt.
Alternatively, open the floppy drive on your desktop, then double-
click on “setup.exe” icon.
The installation program will start, and you will be prompted for
an installation directory (the default is C:\CPWIN). If you would
like to install to a different directory, type the name of the directory
in the box. Click “OK” to continue. NOTE: If you are updating, you
must install the program into the same directory as the previous
version.
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1. Registration (Installing For The First Time)
If you are a new user, you will be prompted to enter the inventory
number of your copy. This number, which helps us prevent
unauthorized installations, is found on two stickers included in the
package, one of which you should place on Disk 1 or the CD. Then
you will be asked to input your name and degree. You will be
recognized as the default user of the program, and your name will
appear on the program’s prescription pad, unless you change that
on the Configure Program screen (see Chapter III).
After the registration routine, you will see the Title screen.
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D. Using The Menubar
Clinical Pharmacology contains four program-specific menus. The
File menu contains file- and printer-related items, the Go To menu
contains navigational items, the Tools menu contains feature-
Help related items, and the Help menu contains help-related items.
Many menu items correspond to buttons that are available on some
or all of the windows in the program. If a button is present and
active (not grayed), the corresponding menu item will also be
active. Choosing the menu item or hitting the associated hotkey
combination is equivalent to clicking the button.
Three menu items deserve mention here. The first, Title Screen, is
the first item in the Go To menu. It is important in a multiple-user
Title
setup, particularly when prescriptions are being generated. In such
Screen a setting, you should not leave the program open under your name,
or another user could write a prescription, or perform other
operations, with your name associated. To avoid unauthorized
access, when you are done with a session, you should log out by
choosing this menu item, hitting <Ctrl>-T, or clicking the Title
Screen button (see “Navigating” in chapters IV and V). Please note
that returning to the Title screen and logging out are functionally
equivalent.
The Tools menu contains the Copy & Paste Utility. Choosing Copy
or hitting <Ctrl>-C changes the cursor to a scissors, after which you
can click over any field, or the chemical structure or color photo-
graph of a monograph, to copy that item to the clipboard for
pasting into the document of your choice. Please note that you must
obtain a license from us in order to use any of the text or graphics for
commercial purposes.
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Chapter III. Configuring The Program: Title Level
The Title level comprises 5 screens: Title, About This Program,
Configure Program, What’s New, and Copyright and Disclaimer.
This level is designed to introduce you to the concepts and people
behind the program and customize its operation for your needs.
A. Title Screen
When you start up Clinical Pharmacology, you will first see the Title
screen, which features the program’s title, logo, and several buttons.
The information in the upper left corner of the screen is the version
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course of browsing the drug information, you have a question
regarding the format in which the information appears, you will
likely find an explanation here.
D. Editorial Staff
The Editorial Staff screen displays a list of the people who have
contributed content to Clinical Pharmacology. You will note a
growing number of qualified professionals from around the
country. We have selected these individuals in order to impart a
contemporary clinical perspective. When you are done, clicking
anywhere on the screen takes you back to the Title screen.
E. Programming Screen
The Programming screen lists the software developers who have
created the program’s interface. When you are done, clicking
anywhere on the screen takes you back to the Title screen.
F. What’s New
The What’s New button takes you to a screen designed to let you
know about the new information and features contained in each
update of the program. With regard to changes to features, you can
expect more detail in the written materials accompanying each
shipment.
The Alphabetical Index button also enters the Index level, and
may also require a user password. After getting familiar with the
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program, many users will want to go straight to this screen when
searching for specific drug monographs.
I. Configure Program
The Configure Program button takes you to the Configure screen,
which has more functionality than any other screen on the Title
level. On this screen, you will customize the program for use at
your particular setting.
1. Users…Privileges
On the left of the screen you will see an area called
“Users…Privileges.” The name of the registered user of this copy of
the program should appear as the only user the first time this
screen is accessed. Subsequently, you decide who will have access
to the information in the program, and to what degree each can
enter information into it. If you are the only user, you should skip
to the “Setting Privileges” section below.
Adding users
Clicking once on Add User below the Users field brings up a
prompt for the new user’s name. Type the name (and title), then
click OK to add the name to the Users list. Repeat this procedure
until you have entered all the user names. To delete a user, high-
light that name by clicking it once, then click Delete User.
Please note that unless the Require user passwords option is
checked, the program is not configured for multiple users. The
name which appears in the first line of the Users field is the default
user of the program if Require user passwords is not checked. To
change the default user, highlight the desired user name, then click
Make Default to move that user to the top of the list.
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Setting privileges
Click twice on any of the users to bring up the Privileges screen for
that user. There are several fields and buttons in the Privileges
window. Start by entering the user password, which is the code
that the user will need to enter in order to gain access to the Index
level of the program. It can contain letters, numbers, and/or
symbols as you wish. You should share this code only with its
named user.
The Next User button takes you to the next user, so you can define
the privileges for that user.
Next User
The Previous User button takes you to the previous user, so you
can define the privileges for that user.
Previous User
The Can Enter Prescriptions option, when checked, allows this
user to add prescriptions to the system and to process prescriptions
for specific patients, thus altering the patient record. In a hospital
setting, this option might be restricted to physicians. However, a
pharmacist might use the prescription-writing system as a record of
prescriptions filled. When you start the program for the first time,
this privilege is automatically given to the registered user. For any
users you enter subsequently, however, the option is unchecked
by default.
The Can Enter Patients option, when checked, allows the user to
add and delete patient records. Judicious use of this option will
give you control over the flow of information going into the system.
When you start the program for the first time, this privilege is
automatically given to the registered user. For any users you enter
subsequently, however, the option is unchecked by default.
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The Contact Information field is associated with each user
primarily in the context of prescription writing. The prescriber’s
name and contact information will appear on the prescription pad
and actual prescription, and will be entered into the Prescriber and
Contact Info field in the Drug Utilization window after the
prescription has been generated.
The Font button brings up a dialog box with which you can choose
the font in which the user’s name and contact information will
appear on the prescription pad. Choose one of the TrueType fonts
from the dialog box and click “OK.” The name of the chosen font
will appear in the field next to the Font button.
2. Options
Require user password
Clinical Pharmacology has been designed to accommodate both
single-user and multiple-user environments, and in the latter case
significant security and management measures are appropriate. If
you plan to use the program at home, or strictly for reference to
drug monographs, then you may wish to speed access to the
information by not requiring user passwords for entry into the
Index level. If so, you should uncheck the Require user passwords
option, bypassing this security feature.
Helpful hint:
For additional security, you may wish to remove these pages from
III - 5
the User Manual after you have established the proper
configuration.
III - 6
or access to disable the saving and exporting features that write text
files to the drive. These features are found on the Report Screen and
in the Quiz and Patient Records portions of the program.
Backup Database
This button allows you to make a backup copy of the “DB”
subdirectory, which contains the user-entered information files
(“Utilize”, “Records”, “Prescr”, “Users”). When this button is
clicked, you will be prompted for a directory in which to store the
backup. The files are placed in a subdirectory (named according to
the date) of the directory you choose.
3. Getting Help
To bring up a help screen at any time, hit F1 or select Context-
sensitive help from the Help menu.
III - 7
Chapter IV. Finding Information: Index Level
The Index level of the program is the gateway to the information in
the drug monographs. A good working knowledge of this level and
its several screens and buttons will greatly speed your access to the
information. Also found at this level are most of the features and
utilities that allow you to utilize the information in unique ways.
While these functions are largely described in Chapter VII, this
chapter will provide an introduction.
A. Index-Level Functions
1. Finding
You can search for textual items using the Find button. Clicking
this button (or choosing Find from the Tools menu) brings up the
Find Find dialog box, into which you type words or parts of words for
the program to locate. The search takes place over the entire Index
level, and if the first match is found on a screen other than the one
you start from, you will go to that screen. The Find function is case-
insensitive, meaning you don’t need to worry about capitalization,
and “wrap-around,” so that a search carried out over the last index
will resume on the first screen and continue from there.
The Options button enlarges the dialog box to reveal two sets of
buttons. The first set represents a “keyboard” for superscripts,
subscripts, and special characters. Clicking on a character types
that character into the Find window at the position of the cursor,
allowing you to search for these characters as well as those
represented on the standard keyboard.
Helpful hint:
There are many cases in which including a special character might
be useful, even when the character is not specifically what you are
IV - 1
looking for, as it would be when finding “∫-blockers.” For example,
in searching for a standardized term, say “Ωaspergillosis,” you can
include the bullet and guarantee the correct first match with fewer
characters typed. The characters “Ωasp” are found first on the
Indications Index, whereas “asp” is found first on the Main Index.
To the right, the second set of buttons customizes the starting point
of the search; this is really just a matter of personal preference in
most cases, but sometimes you will want to be aware of the
difference. In the default setting, Find searches from the first index
(the first screen of the Main Index). If you usually search for drug
names, this is helpful because it guarantees you will find your entry
in the Main Index, from which you can quickly access the mono-
graph. In the other setting, Find searches from the index you are
presently viewing. This setting is most useful when trying to locate
an item that appears in several indexes; locating a drug name in the
References Index is a good example. For items that appear only
once on the Index level, the starting point of the wrap-around
search is irrelevant.
After bringing up the window with the Find button, simply type
the search characters, which will replace any text previously stored
Find there. You can also insert the cursor into the text field without
erasing the contents by clicking in the desired location. Click Find,
or hit <return> or <enter>, to locate the occurrences of the text on
the Index level.
After a successful search, the Find dialog box disappears and the
line on which the search characters were first found is highlighted.
You may be on a different screen than the one you started on. If
there is more than one occurrence, a Results window appears
listing each line, and its location on the Index level, in which the
characters were found. Clicking on any line in the Results window
takes you to the appropriate index and highlights the line. Because
the Find feature takes you automatically to the first occurrence of
the characters, you have, in effect, already “clicked” on the first line
of the Results window.
IV - 2
The Results window is a “floating” window, meaning that it will
exist on top of other windows, including the active window. The
Results window will stay open until you explicitly click the
window’s close box or bring up the Find window with the Find
button. This allows you to use the Find Results window as a
flexible navigational tool until you need to execute another search.
2. Type-Searching
Any of the indexes that presents an alphabetical list of terms can be
searched by simply starting to type the desired entry. For example,
in locating “Propranolol” in the Alphabetical Index, typing “P”
highlights the first drug that begins with that letter; then “R” takes
you to the first drug that starts with “Pr”, etc., until eventually
“Propranolol” is highlighted. Clicking the mouse or hitting the
space bar clears the letters from memory, so you can type a new
character combination.
There are ways to highlight an item besides clicking it. For instance,
using the Find function highlights the located text. On the alpha-
betical indexes, typing the first letter(s) of a term highlights the first
appropriate term. When you return to the Index level from the
Monographs level, the program will highlight a term based on your
last activity.
4. List Reporting
On several of the indexes–those corresponding to the list-based
fields on the right side of the monographs, starting with the
Indications Index–the List button is found. This button is disabled
until you highlight a term, after which clicking the button (or
List choosing Generate Report from the Tools menu) brings up a dialog
box, allowing you to generate a report of all the drugs in the Main
Index that share the highlighted characteristic. Thus, you can make
IV - 3
a report of all the drugs used for a certain medical condition (by
using List from the Indications Index), or of all the drugs which
produce a certain adverse reaction (Adverse Reactions Index), or of
all the drugs produced by a certain manufacturer (Product Identifi-
cation Index), etc.
There are three options you can set for a List report. The first,
Include cost information, will compile information regarding the
costs of each drug in the list. Including costs is useful, for instance,
when listing drugs that can treat the same indication, or to compare
costs within a therapeutic classification (by Listing from the
Classification Index). The second, Don’t alphabetize, lists the
drugs in the order they appear in the Main Index, rather than
alphabetically (the default). Some feel that an alphabetical list is
less likely to be interpreted as “prioritized”—which List reports are
not. The third, Include mini-monographs, applies only to lists of
Indications and Classification terms. Since (only) these items are
found in the mini-monographs, you can include the drugs
represented by mini-monographs in your lists.
The List report is placed into the Report screen on the Index level,
erasing any report previously residing there. The list is a “hot list,”
so you can click twice on any drug to access its monograph. When
you click the Index Level button, you will come back to this screen
Index so that you can “bounce” back and forth between the report and
Level several monographs.
5. Printing
You can print any of the screens on the Index level by clicking the
Print button, or choosing Print from the File menu, either of which
Print will bring up a dialog box. Click OK to print the desired index.
6. Getting Help
You may bring up a help screen at any time by hitting F1 or
selecting Context-sensitive help from the Help menu. You can
IV - 4
search for help on a specific topic by choosing Search for help on...
from the Help menu.
Help
B. Navigating
1. Returning to the Title screen (Logging out)
By clicking the Title Screen button on the Program Map, you not
Title only navigate back to the Title level, but also log out, because, when
Screen Require user password is in effect, any future user will have to log
in before returning to the Index level. You can also choose Title
Screen from the Go To menu to return to the Title screen. If there
are prescriptions waiting to be printed under the 4-per-page option,
these will print before logging out.
4. Quitting
Use the Quit button to bring up a dialog box from which you can
exit the program. You can also choose Exit from the File menu. If
the Backup database upon quitting program option is checked,
Quit you will be notified that a backup is taking place. If there are
prescriptions waiting to be printed under the 4-per-page option,
then these will print before quitting.
C. Indexes
1. Main Index
This index lists the most common and classic drugs in current
clinical use by therapeutic classification. For each of these drugs,
there is a full monograph. You access the monograph by clicking
twice on the drug name (once if the name is already highlighted).
2. Alphabetical Index
This index lists all the drugs from the Main Index alphabetically by
IV - 5
generic name. Since type-searching is active on this screen, it often
provides the quickest way to access a specific monograph. High-
light the drug name by type-searching or by clicking once on the
unhighlighted name, then click on the highlighted drug name to go
to the monograph.
Nutrient/drug interactions
Each component of the nutritional product which might be
IV - 6
expected to cause a drug interaction has the entry “œ[component]
interactions”. To access more information on a nutrient/drug
interaction, click on any arrow (“œ”) to create an indented list of
the drugs that interact with that nutrient component. Then, click
twice on any drug to access a description of the interaction on the
nutrient’s Interactions screen. Click the Interactions window’s close
box to return to Nutritional Products.
IV - 7
product name. Click once on a highlighted product in the admix-
tures table to display the information into a statement about the
products’ compatibility, which will appear in a floating “statement
window.” You can add more statements to the window by clicking
twice on other products in the admixtures table. Clicking Create
Report compiles the statements into an Intravenous Admixtures
Report. The result will be placed onto the Report screen, from
which you can print or save it.
9. Indications Index
This index of standardized terms lists the medical conditions that
appear as an indication in at least one full monograph. Highlight
an indication by type-searching or by clicking once on an
unhighlighted item. This action enables the List button, with which
you can list all the drugs that are indicated for the condition. Drugs
List that are used but not FDA-approved for the indication are marked
with a dagger (ß).You can include the drugs represented by
mini-monographs by checking Include mini-monographs under
Options. Clicking on a highlighted indication takes you to the first
monograph that features the condition as an indication (and you
can subsequently cross-reference the other monographs that do).
IV - 8
in at least one full monograph. Highlight an item by type-searching
or by clicking once on the unhighlighted item. This action enables
the List button, with which you can list all the drugs that interact
with the selected drug or class. (Since you can see the drugs that
List interact with a given drug in that drug’s monograph directly, this is
most useful for classes of drugs and individual drugs not found in
the Main Index.) Clicking on a highlighted item takes you to the
first monograph that features the interaction.
IV - 9
13. Costs Index
This index lists standardized phrases that pertain to the absolute
and relative costs of drug therapy. The statements are grouped into
categories for easy reference. At the top of the Costs Index field is
an overview of the categories, and you can click on any item above
the solid line to go to that section of the index. Highlight a cost
statement by clicking once on the unhighlighted item. This action
enables the List button, with which you can list all the drugs for
which the statement applies. Clicking on a highlighted statement
List
takes you to the first monograph that features the statement as
pertinent costs information.
This index also houses the Costs Report, which allows you to
compile costs information for any number of full-monograph
drugs. To begin, click the Costs Report button, which takes you to
the Alphabetical Index in data-entry mode, in which there is a field
on the right side of the screen to accept your entries. You can type-
Costs
Report search, scroll, or use Find to locate a drug, then click on it to add it
to the list. Click again on a drug already listed to remove it from the
list. When you are done, click the Costs Report button again to
bring up the Profile window. Clicking OK will generate the report
and place it on the Report screen. For more information about the
Costs Report, please see Section A of Chapter VII.
IV - 10
the pertinent photo will be displayed. Hopefully the photo will
enable you to identify the dosage form. If not, you can then use the
Product
Product Identification Utility button, which now appears in the
Identification Monographs window, to locate the next match. Please see Section B
Utility of Chapter VII for more information about this utility.
IV - 11
the naming convention of “[up to 8 characters].pat” in order to be
recognized by the program. See Section E of Chapter VI for a
discussion of exporting patient records.
After the record is imported, you will see a new entry in the Patient
Records Index and there will be a new screen in the Patients
window. There may also be Drug Utilization and Patient History
screens for the imported patient.
The Patient Records Index houses the Add, Delete, and Modify
Patient buttons. Chapter VI contains a full description of these
functions. The Table button, discussed in Section F of Chapter VII,
Add/Delete
Patient is also found here.
19. Report
This screen holds the last report generated by the program. If the
report is a List Report, it is an “index” in the sense that you can
access the monograph of any drug in the report by clicking twice
on the name.
You can save any report as a text file using the Save To Disk button
or selecting Save Report from the File menu. Clicking this button
brings up a dialog box with which you can give a name and
Save to
Disk location for the file. You may save files in text only format (TXT) or
rich text format (RTF) by choosing the appropriate extension from
IV - 12
the combobox. The rich text format maintains text formatting, and
is readable by most word processing programs.
20. Quiz
This screen holds the last quiz generated by the program. If the
program has not quit since the generation of the quiz, the answers
will be in memory so that the quiz can be taken interactively by
clicking on multiple-choice items. The Quiz button, found on this
screen, brings up the Quiz window, from which you generate new
Quiz
custom questions. Section D of Chapter VII covers the Quiz utility
in full detail.
You can save any report as a text file using the Save To Disk button
or selecting Save Quiz from the File menu. Clicking this button
brings up a dialog box with which you can give a name and
Save to
Disk location for the file. You may save files in text only format (TXT) or
rich text format (RTF) by choosing the appropriate extension from
the combobox. The rich text format maintains text formatting, and
is readable by most word processing programs.
IV - 13
Chapter V. Browsing and Cross-Referencing
Information: Monographs and More
Information Levels
The Monographs level is the heart of Clinical Pharmacology. It
contains the majority of the information in the program. Textual
links make it easy to request and locate the more detailed descrip-
tions presented on the More Information level. An ellipsis (“…”) in
or after a field name indicates that more information is available.
A. Monograph Content
The content in the drug monographs is designed to minimize
the time and effort it takes to locate information. The material is
divided among several fields, which are always found in the same
place and have the same format within the Monographs window.
Each drug has its own screen in the window, so that, for instance,
the “Verapamil monograph” is equivalent to the “Verapamil screen
on the Monographs window.” This section will take you stepwise
through the fields found on and accessible from the Monographs
window.
The Brand Names field, just below, lists the common brand names
for the drug as well as any generic products for which there is a
color photo available. There are two buttons at the right of the field
with which you can scroll horizontally. When you access a mono-
graph, the program searches the Brand Names field and puts the
first available photo into the Color Photographs area. However,
V-1
clicking on other brand names displays the appropriate photos, if
available. If clicking on a brand name empties the Color Photo-
graphs area, then no photo is available for that product. The mouse
pointer changes to a hand when over the Brand Names field to
indicate that a mouse click can change the current photograph.
4. Indications…Dosage
The Indications field lists the medical conditions this drug is used
to treat. Non-FDA-approved indications are included and marked
V-2
with a dagger (ß). Click once on an indication to highlight it and
enable the List and Cross-Reference buttons.
Cross-Reference
Click on a highlighted indication to request more information in
the form of dosing guidelines found in the Dosage window. The
indication you clicked will be located and highlighted for quick
reference. From here you may navigate within the Dosage window
or use the Prescribe button to bring up the prescription pad (see
Prescribe Chapter VI). To return to the monograph, click the Dosage
window’s close box.
5. Contraindications/Precautions…
The Contraindications field lists the medical conditions in
which this drug must not be used (contraindications, listed in
italics) or must be used with caution (precautions). These
concepts are sometimes expressed as “absolute” and “relative”
contraindications. If you generate a prescription for a patient with
any of the conditions listed here, the program will warn you (see
Chapter VI). Click once on a condition to highlight it and enable
List the List and Cross-Reference buttons.
6. Drug Interactions…
The Drug Interactions field lists the drugs (preceded by “Ω”) and
classes of drugs (preceded by “œ”) that have clinically significant
interactions with this drug. Clicking once on an arrow produces an
indented list of all the drugs in the Main Index in this classifica-
tion; clicking on the downward arrow (“∑”) that then appears
before the class will remove the list from view. Click once on any
drug or class to highlight it and enable the List and Cross-
Reference buttons.
7. Adverse Reactions…
The Adverse Reactions field lists the conditions that represent
clinically-significant adverse reactions to this drug. We consider
significant side effects to be those of high frequency (in general,
V-3
with >5% incidence) or high severity. Click once on any item to
highlight it and enable the List and Cross-Reference buttons.
8. OBRA…Patient Information
The OBRA field is designed for patient counseling. OBRA stands
for the Omnibus Budget Reconciliation Act of 1990, a component of
which requires patients to be offered counseling at the time of
dispensing of medications.
At the top of the OBRA field, above the solid line, each of the
dosage forms for which there is distinct counseling information is
listed. For example, the information on administration of a tablet
might be quite different from that pertaining to an eye drop. One of
the dosage forms is selected, and the selection is bold. Click once on
any dosage form to select it.
Below the solid line are several standardized terms representing the
counseling requirements mandated by OBRA. Click on a high-
lighted term to request more information in the form of a brief
description found in the Patient Information window. Each
Patient Information screen as a whole is a complete patient
counseling form, satisfying OBRA, designed for you to print and
hand to your patients. You can print handouts either individually
from the monograph (see Printing in Section B), or in groups
with a cover sheet from within a patient record (see Section C
of Chapter VI). The counseling term you clicked will be located and
highlighted within the Patient Information handout; you will
notice that the heading is in the context of the layperson. From
here you may navigate within the Patient Information window or
click the window’s close box to return to the monograph. Note
that the handouts for different forms of the same generic are
always adjacent.
V-4
bulleted (“Ω”) costs item to highlight it and enable the List and
Cross-Reference buttons.
11. Classification…Overview
The Classification field contains two sets of standardized items
that pertain to the classification of the drug. The first set of terms,
preceded by arrows (“œ”), is indexed in the first screen of the
Classifications Index and summarizes the classifications for the
drug as found in the Main Index. Drugs that have more than one
classification (each classification starts with an unindented line) are
listed the corresponding number of times in the Main Index.
V-5
B. Monograph-Level Functions
3. List Reporting
You can make a list of all the drugs in the Main Index that share a
given standardized term with the List button. This button is
disabled until you highlight a term, after which clicking the button
List brings up a dialog box, from which you generate the report. You
can also choose Generate Report from the Tools menu. The report
lists all the monographs in which the highlighted term appears in
the currently selected field, e.g., Indications, Contraindications, etc.
There are three options you can set. The first, Include cost informa-
tion, will compile information regarding the costs of each drug in
V-6
the list. Including costs is useful, for instance, when listing drugs
that can treat the same indication, or to compare costs within a
therapeutic classification. The second, Don’t alphabetize, lists the
drugs in the order they appear in the Main Index, rather than
alphabetically (the default). The third, Include mini-monographs,
applies only to lists of Indications and Classification terms. Since
(only) these items are found in the mini-monographs, you can
include the drugs represented by mini-monographs in your lists.
The List report is placed into the Report screen on the Index level,
erasing any report previously residing there. Drugs with mini-
monographs are marked with an asterisk (*). The list is a “hot list,”
so you can click twice on any drug to access its monograph. When
you then click the Index Level button from a monograph, you will
Index come back to this screen so that you can “bounce” back and forth
Level between the report and several monographs.
4. Printing
Printing from the Monographs window is extremely flexible. Click
the Print button or choose Print from the File menu to bring up a
dialog box from which you customize the printout. The prompt in
Print the dialog box reflects the last print request. If you wish to repeat
that request for this monograph, simply click OK and your printout
will be generated and printed. Otherwise, choose from the list of
the items you can include in the printout. If you wish to print the
complete monograph, click All, which will select all the items. To
start from scratch, click None to deselect all the items. Then simply
click on any item to select or deselect it. When you have customized
the printout to your liking, click OK.
Because each printout is custom, it will take a short time for the
program to format the information. The phrase “Your document is
V-7
being sent to the printer” will appear in a window while this is
occurring. When this window disappears, returning you to the
Monographs window, the program has done its work, and you
may resume normal use. Depending on your printer configuration,
it may take several minutes for the formatted information to
actually print.
5. Finding
You can search for other drug monographs using the Find button.
Clicking this button (or choosing Find from the Tools menu) brings
Find up a dialog box, into which you type all or part of a drug name for
the program to locate. You can search for generic or brand names.
The Find function is case-insensitive, meaning you don’t need to
worry about capitalization, and “wrap-around,” so that a search
carried out over the last monograph will resume on the first
monograph and continue from there.
After bringing up the window with the Find button, simply type
the search characters, which will replace any text previously stored
there. You can also insert the cursor into the text field without
erasing the contents by clicking in the desired location. Click Find,
or hit <return> or <enter>, to execute the search. The search is
actually carried out on the Index level over the indexes that contain
drug names, i.e., the Alphabetical Index through the Discontinued
Products Index.
After a successful search, the Find dialog box disappears and you
are taken to the first monograph that features a drug name contain-
ing the specified characters. You will likely be on a different screen
than the one you started on; in fact, if the first match is not in the
Alphabetical Index, another window, such as Less Common Drugs,
may now be active. If there is more than one occurrence of the
characters, a Results window appears listing each line, and its
location on the Index level, in which the characters were found.
Clicking on any line in the Results window takes you to the
appropriate monograph or mini-monograph. Because Find takes
you automatically to the first monograph featuring the characters,
you have, in effect, already “clicked” on the first line of the
Results window.
V-8
Further, the Results window will stay open until you explicitly
click the window’s close box or bring up the Find dialog box
with the Find button. This allows you to use the Find Results
window as a flexible navigational tool until you need to execute
another search.
6. Getting Help
You may bring up a help screen at any time by hitting F1 or
selecting Context-sensitive help from the Help menu. You can
Help search for help on a specific topic by choosing Search for help on...
from the Help menu.
C. Navigating
The buttons described in this section perform strictly navigational
functions. A good working knowledge of these buttons will
significantly speed up your usage of the program.
V-9
access the full citation (and then return to the monograph). Choos-
ing an index from the Go To menu is equivalent to clicking the
Index Level button.
Helpful hint:
If you are frustrated by “out-of-sequence” monographs, don’t forget
that you can cross-reference an arrowed (“œ”) entry in the Classifi-
cation field to quickly navigate between all the drugs in a given
therapeutic class.
5. Quitting
Use the Quit button to bring up a dialog box from which you can
exit the program. (You may also choose Exit from the File menu.) If
Quiz the Backup database files upon exiting option is checked, you will
be notified that backup is taking place. If there are prescriptions
waiting to be printed under the 4-per-page option, then these will
print before quitting.
V - 10
Chapter VI. Entering Information: Patient
Records and Prescription-Writing
Much of the power of Clinical Pharmacology lies in its ability to store
information about a real or simulated patient and then to generate
reports, handouts, and prescriptions for and about the patient.
Adding and maintaining patient records is a process that will save
you time in everyday clinical situations. It will also reveal much
information that you can learn from and use in patient care.
Click the New Patient button to bring up the Patient Records window.
Helpful hint:
You may wish to keep several different records for a single patient,
each perhaps representing a hospital stay. Doing so ensures that
VI - 1
you have a record of the patient’s drug therapy at some specific
time in the past always available to you. However, you can’t have
more than one active record for a given record number at once.
Please see Section E for information on exporting patient records.
The program then asks for the patient’s name. Because the patients
will be listed alphabetically by last name, please input the name in
Last, First format. Click OK to continue.
2. Medications
Rather than type in the patient’s current medications, you choose
them from the pertinent indexes, ensuring that the program knows
exactly which drugs you are giving, so you get accurate reports.
Each time you click the New Patient button, the Patient Records
window will pop up. If you need to add more medications, click
Cancel to dismiss the window; when you have entered all the
New Patient
current medications, click OK on the Patient Records window.
lick OK on the Patient Records window.
Helpful hint:
Don’t forget that ethanol, nicotine, caffeine, amphetamines, and
narcotics have significant interactions and can constitute serious
VI - 2
precautions to many prescription drugs. Include these commonly
abused substances, which have full monographs in Clinical
Pharmacology, in your patient records when appropriate.
3. Medical Conditions
The program next wants to know your patient’s medical condi-
tions. Entering these will allow you to associate each of the
patient’s drugs with a medical condition in the Drug Utilization
window, which will allow you to take advantage of the features of
that window. The Drug Indications/Medical Conditions Match in
the Patient Profile (see Chapter VII) analyzes these entries for you.
Additionally, this information makes drugs/contraindications
warnings possible. Again, you choose the conditions from indexes
so that these utilities work properly.
Helpful hint:
Especially with regard to the conditions in the Contraindications
Index, don’t forget to list even those conditions that you aren’t
treating pharmacologically. Many of the contraindications are
broad terms meant to cover a lot of ground in drugs/
contraindications warnings: e.g., “Ωhepatic disease.” You will be
surprised how much good information you can uncover if you are
thorough in entering medical conditions.
4. Allergies
The last piece of information the program always asks about is
allergies, so that the program can warn you if you attempt to
prescribe a drug to which your patient is allergic. Entry of allergies
is done from the Main Index so that you may enter both individual
drugs and drug classifications. Scroll or use Find to locate the
classification, then click on it to add it to the allergies list. Click
again on an allergy already listed to remove it.
VI - 3
Use the Previous and Next Index buttons or the Find utility to
navigate between the two screens of the Main Index. Each time you
Previous/Next click the New Patient button, the Patient Records window will pop
Index up. If you need to add more allergies, click Cancel to dismiss the
window; when you have entered all the patient’s allergies, click OK
on the Patient Records window.
New Patient
5. Other Information
You have created a patient record containing the essential informa-
tion, and now you see the record, with the Patient Records Index
underneath. There are several other fields into which you can enter
data by clicking in the field (or tabbing between fields) and typing:
Address & Telephone, Date of Birth, Weight, Gender, and Renal
Function. The last two fields have associated comboboxes you can
use to make standardized entries. You can further edit the entry if
you wish.
VI - 4
B. Modifying Patient Records
Once you have created a patient record, modifying it is easy. To
access a patient record, simply type-search, scroll, or use Find to
locate its listing in the Patient Records Index.
If you are accessing the patient records over a network, you may
receive a message that the record is locked, so you can’t modify it.
If so, all of the fields will be locked and the Modify buttons (see
below) will be disabled. You must try to access the record again later.
Helpful hint:
You may find it extremely useful to use the modify routines not only
to reflect changes you have already made to a patient’s drug regimen,
but also to audition changes. You can add a prospective drug, then
search for interactions, contraindications, etc. with the Patient
Profile before actually prescribing it. For that matter, you can build
entirely simulated patient records in order to do this type of thing!
VI - 5
you to confirm your choice before removing the entry. You should
strongly consider exporting the record before you delete it (see
Section E below), since this will allow you to reincorporate the
patient into your system at a later date.
VI - 6
For some of the drugs, there may be more than one Patient Information
handout, each corresponding to a different dosage form. In this case,
the program will prompt you to select from a list of available hand-
outs. Also note that there is no patient information available for
drugs represented by mini-monographs (marked with an asterisk).
The utility first asks if you would like to print the prescriptions or
simply process and record them. If you need a “hard copy” of the
prescriptions to sign and hand to your patient in addition to the
processing and recording, click Print. If you are using the utility
simply to process and record the refills, click Process Only.
VI - 7
D. Patient History
From the Patients window, you can click the Patient History button
to bring up the patient’s screen in the Patient History window. This
Patient window contains one large field for you to type in information
History regarding the patient’s clinical presentation and history. Entering a
patient history might be particularly valuable if you export the
patient record to send to someone else, if others will be using this
program to contribute to the patient’s care, or in an educational
setting.
F. Drug Utilization
The Drug Utilization window contains much of the detailed
information about your patient’s drug regimen, and is the gateway
to patient-specific prescribing. However, it has significant function-
ality in its own right: it is designed to help you identify trends in
your therapeutic practices by allowing you first to associate an
outcome with each patient-drug combination, and then to cross-
reference drugs, medical conditions, and prescriptions among your
patients. You can also use the Table Utility (Section F of Chapter
VII) to tabulate the data in an easy-to-read spreadsheet format.
VI - 8
1. Accessing Drug Utilization Screens
There are three ways to access the Drug Utilization window. The
first is to click twice on a drug in the Current Medications field of
the Patients window. This action brings up the screen specific to this
drug and this patient, which is the basic premise behind the Drug
Utilization window. The second is to click twice on any condition
in the Medical Conditions field; if the condition has been associ-
ated with any of the Drug Utilization screens, the first one will pop
up (if not, the program will inform you). The third is to click twice
on any prescription in the Prescriptions Index. If the prescription
has been processed for any patients in the patient records system,
the first patient’s Drug Utilization screen for that drug will appear.
VI - 9
choosing from the list of medical conditions you have previously
defined for this patient. The list is stored in the combobox. If you
wish to clear the field, choose “none.”
4. Prescription History
The Prescription History field contains a line entry for each
prescription generated for this drug for this patient. The entry
consists of the date followed by the actual prescription data. By
clicking once on any prescription, you enable the Next and Previ-
ous Cross-Reference buttons, with which you can see the other
Drug Utilization screens containing this exact prescription. Do this
in order to analyze the results you are getting with this particular
form and dosage.
5. Comments/Outcome
The Comments/Outcome field is the key element in the Drug
Utilization system. By entering information about the relative
success or failure of therapy with this drug in this patient, you
allow yourself the opportunity to access this information via the
cross-referencing features described above.
VI - 10
The next section is devoted to a thorough description of both
patient-specific and non-patient specific prescription processing.
Please note that you always bring up the prescription pad in the context
of a specific drug. The context is important, because a generic name is
VI - 11
always associated with the prescription you are writing. By
keeping this association, the program is able to give you quick
access to all the prescriptions you have given for a drug, even if
you have prescribed for specific brand names.
Helpful hint:
Bringing up the prescription pad on top of the Dosage window is
an excellent way to have dosing information at your fingertips as
you write prescriptions.
You can leave any of the fields, including Patient Name and
Record #, blank; in fact, for the purpose of building your Prescrip-
tions Index, you will want to leave those two fields empty (these
are non-patient-specific prescriptions).
VI - 12
When you are done writing the prescription, click the Print
Prescription button to bring up a dialog box, from which you can
Print
process the prescription. Uncheck the printing options, should
Prescription either be checked. Since there is no patient associated with this
prescription and we are not going to print it, there is minimal
“processing;” click OK, and the program will simply check the
Prescriptions Index, and if this exact prescription is not already in
the index, it will add it as a new listing. You may subsequently
bring this prescription up by highlighting it and clicking the Prescribe
button on the Prescriptions Index screen. A thorough discussion of
Prescribe the processing and printing of prescriptions appears in Section 3.
VI - 13
listed in the index. If there is more than one prescription associated
with this generic name, the Next and Previous Prescription
buttons will be enabled. You may edit any field, but the prescrip-
Previous/Next tion will still be associated with the original generic. You can enter
Prescription a patient name and/or record number, and if that patient has a
record in the system, it will be updated accordingly as the prescrip-
tion is processed (see next page).
VI - 14
Click OK to process the prescription. The first step the program
takes is to verify that the generic name associated with this pre-
scription is correct, because this is critical to the patient records
system and the Prescriptions Index. Again, you will always have
brought up the prescription pad in the context of a particular
generic, and this is the default association. However, now the
program searches for the entry in the Main Index, then in the New
Drugs, Combination Drugs, and Less Common Drugs Indexes.
There are two possible types of mismatches.
1) The program can’t find the drug name on the Index level.
In this case the program assumes that you have prescribed a
specific brand name that isn’t listed in the index. You are
notified of the generic that’s currently associated with this
prescription, and you may click Cancel if it is incorrect.
Otherwise click OK and the association will be made; in the
future this prescription will be made available to you when
you prescribe for that generic.
2) The program finds the drug name listed in the index under
another generic. In this case the program assumes that you have
called up the prescription pad in the context of one generic, but
rewritten the prescription for another drug. You are notified
of the original generic association, and the program offers to
change that association to the generic it has found during the
search. Click Change to accomplish this. If the program has
erred and you want to maintain the original association, click
Don’t Change. If you’d like to start over, click Cancel Script.
Helpful hint:
Making sure that you have associated the right generic with the
prescriptions you generate will preserve the integrity of the patient
records as well as maximize the functionality of the prescription
Previous/Next pad, since you can access all the prescriptions for a given generic
Prescription quickly with the Next and Previous Prescription buttons.
VI - 15
medical conditions in the patient record. If a contraindication
is found, the program notifies you with a drug/contraindica-
tion warning. You must then click either Cancel, which
cancels the prescription, or OK to override the warning and
continue the processing. There may be more than one drug/
contraindication warning, in which case the notifications
appear in succession.
VI - 16
Chapter VII. Utilizing Information: Reports
and Utilities
There are several reports and utilities in Clinical Pharmacology that
allow you to do things you normally don’t have time to do. This
chapter describes these features in detail, so once you are familiar
with them you can put them to use in your everyday practice.
A. Patient Profile
The patient records system in Clinical Pharmacology is useful for
recordkeeping, but that’s not the best reason to input patient data.
Once you have generated a patient record, you can create a custom
profile including any or all of the reports listed below. To do this,
click the Profile button on the Patients window to bring up a
Profile dialog box. The checked items will be included in the profile. When
you have customized the request, click OK and the program will
generate the profile and place it in the Report screen. From here
you may review the profile, then print it or save it to disk (see
Report in Section C of Chapter IV).
VII - 1
Helpful hint:
Because the mini-monographs contain the classifications of the
drugs, they will be included in the Interactions Report. However,
any description of the interaction will of course have to come from
the Interactions screen of the other drug, and thus may be viewed
as “incomplete.” One approach you may consider is to list the
component drugs of combination preparations separately (they
often have individual full monographs, with “complete” interac-
tions information) in the patient record, especially if you are not
using the prescription generation utilities.
3. Costs Report
This report helps you estimate the total cost of a patient’s drug
VII - 2
regimen by compiling the Total Cost of Therapy information from
the Costs field of the monographs. Since there is no costs informa-
tion on the mini-monographs, these drugs are not included.
The report lists each drug and the pertinent costs information for
each. Often there will be figures given for several common dosages.
5. Drugs/Contraindications Warning
This report lists all appropriate drugs/contraindications warnings,
with descriptions, for this patient. (These are the same warnings
that appear automatically when you process prescriptions for the
drugs in question.) It works by checking a compiled list of the
standardized terms in the Contraindications/Precautions fields of
the monographs against the list of medical conditions defined for
VII - 3
the patient in the Medical Conditions field of the Patients window.
When the program identifies a warning, it locates appropriate
paragraph in the Contraindications window and includes that
description in the report. Because there is no Contraindications
field on the mini-monographs, these drugs are not included.
Helpful hint:
This report is most functional when care has been taken to include
conditions from the Contraindications Index, as well as the
Indications Index, in the Medical Conditions field. Don’t limit
your entry of medical conditions to the ones you are treating
pharmacologically. Remember to include smoking and alcohol
consumption as well.
Because this report requires so much data from the patient record,
there is no non-patient-specific version; you must generate it from
the Patients window.
6. Drugs/Allergies Warning
This report lists all appropriate drugs/allergies warnings for this
patient. (These are the same warnings that appear automatically
when you process prescriptions for the drugs in question.) It works
by checking a compiled list of the standardized terms in the
Classification fields of the monographs against the list of allergies
defined for the patient in Allergies field of the Patients window.
Mini-monographs do contain the classification information, so the
program will catch allergy warnings for these drugs too.
Because this report requires so much data from the patient record,
there is no non-patient-specific version; you must generate it from
the Patients window.
When you are done, click the Product Identification Utility button
again, and the program will search for the first dosage form that
matches the description. If it finds a match, you will go to the
monograph featuring the photo of the dosage form. The specific
form in the Product Identification field will be highlighted, and
the pertinent photo will be displayed. Hopefully the photo will
enable you to identify the dosage form. If not, you can then use the
Product Identification Utility button, which now appears in the
Monographs window, to locate the next match.
Keep in mind that the Quiz utility is a question generator and that
there are no stored “question banks.” You must therefore save the
questions to disk, or print them, in order to preserve and modify
them, since each time you generate a new quiz it replaces the
previous one.
VII - 6
The Quiz screen is found on the Index level. Clicking on the Quiz
button brings up the Quiz window, where you define many things
about the way the questions are created and answered.
Quiz
1. Quiz Options
Subjects
The first set of options defines the pharmacological subjects for the
questions. You can select one or more of Indications,
Contraindications, Interactions, and Adverse Reactions as you like.
# of questions
Next, tell the program how many questions you’d like by typing in
a number from 1 to 100.
# of multiple-choice options
You can generate questions with 4 or 5 answers apiece; the pro-
gram generates 4-answer questions a little faster.
VII - 7
Drugs as answers, or both to indicate your wish. The Drugs as
questions option generates questions about twice as fast as Drugs
as answers.
2. Quiz Topics
Click Topics to go to the Classification Index in data-entry mode.
You can click on any item above the solid line to go to that part of
the index; hit the up arrow key to return to the top of the index.
You can also scroll or use Find in order to locate the topic or topics
that interest you. Click once on any classification to add it to the
topics list; click on any item already in the list to remove it. You
may add as many topics as you like; then click the Quiz button to
return these topics to the Quiz screen, at which point you will be
Quiz prompted to click OK in order to generate the questions.
If answers are not displayed, then until the program quits they are
stored in memory so that you can take the quiz interactively. If
Multiple responses was not checked, then you have one try per
question. Simply click on answer you think is right, and the
program will give you feedback with “Correct” or “Incorrect”
followed by answer. The last paragraph of answer is always the
description of the indication, contraindication, interaction, or
adverse reaction in the question. If requested, the description of the
drug about which the question is asked appears first. If you
guessed incorrectly, the letter of answer you chose becomes an “X”
so you can review your responses later.
VII - 8
If Multiple responses is in effect, then you are awarded points
based on how early you guess correctly. For 4-option questions,
100, 66, 33, and 0 points are awarded for correct responses on the
first, second, third, and fourth try, respectively; for 5-option
questions, 100, 75, 50, 25, and 0 points are awarded. If you guess
incorrectly, the letter of answer you chose becomes an “X” and you
can’t choose that response again.
You can see your score at any time during the quiz by clicking the
Quiz button. Your score will be displayed in the Quiz window.
You have the option to start a new quiz or save the current one.
Quiz Click OK or the close box to return to the present quiz.
From the Program Map on the Index level, navigate to the Logical
Search screen. The screen holds the last search request executed; in
order to start over, click New Request. Now, build the request,
starting with the first item.
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1. Building a Search Request
Each item consists of four elements: an index in which the standard-
ized term is located; “contains” or “does not contain”; the standardized
term to be searched for; and a concatenator joining this item to the
next. These elements are represented by the four comboboxs
grouped together in the lower right of the screen.
As you build a search request, you work on one item at a time. This
“active” item is underlined in the Search Request field. At any
point in building a request, you can click on any item, whether
complete or incomplete, to make it active. The contents of the
comboboxes and sets of “radio-style” buttons below the Search
Request field reflect the elements in active item. An empty element
is represented by an asterisk (*) in the Search Request field with an
arrow to the left of the corresponding combobox or button set.
After clicking New Request, there is one empty item in the search
request (“* * * *”). Since it is active item, it is underlined. You use
the comboboxes and radio buttons to fill the elements of active
item. In our example, we are looking for drugs where the Indica-
tions field contains the term “Ωhypertension” and the
Contraindications field does not contain the term “Ωpregnancy.”
Let’s consider each element in turn as we build the first item:
“Indications contains ‘Ωhypertension’ and.”
Index
The Item Index button (first combobox) contains the names of the
eight indexes that can be included in the search request. These
indexes correspond to the list-based fields in each monograph. To
search for drugs indicated for hypertension, choose “Indications”
with the button. This 1) defines “Indications” as the first element in
active item and 2) puts the contents of the Indications Index into
the Search Index field on the left of the screen.
Standardized term
This element defines actual term to be searched for in appropriate
field of the drug monographs. You choose the term from the
corresponding index, which is already loaded into the Search Index
field. You can scroll, type-search, or use Find to locate the term of
interest, then click it to choose that term. Choose “Ωhypertension”
from the Search Index field.
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Concatenator
The Concatenator buttons are “and,” “or,” and “end.” These
represent the options for linking this item of the request to the next.
If this is the last item, and the request is complete, then “end” is
appropriate choice.
Helpful hint:
After the program performs a concatenation operation, it discards
the original two lists. Any later concatenation operation is thus
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performed using the new list. So if in our example there were a
third item, the concatenation operation would be performed on this
new list and the list from the third item’s criterion. This is the linear
flow of the search. If you wish, you can use the Compare Results
button (see below) to customize the flow of your search.
Navigating
Below the first line of the results window is an alphabetical list of
all the drugs that satisfy the search request. You can click on any
drug name to navigate to its monograph.
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Try executing a new search while the Search #1 screen of the
Results window is visible. The results are placed on the Search #2
screen of the Results window. On the Options screen, you can
perform a specified logical operation between the lists of drugs in
the two search screens. Between these two screens, the options are
#1 and #2 (“and”), #1 or #2 (“or”), #1 or #2 but not both (“exclu-
sive or”), #1 but not #2 (“not”), and #2 but not #1. When all three
search screens are filled, you may pick which two screens to
combine. Click Compare Results to execute the operation, the
results of which are placed in the Combined screen of the Results
window.
If you are familiar with mathematical logic, you can see one
advantage of this approach: it allows you to break away from the
linear execution of the complex search request. In mathematical
terms, it allows you to do parenthetical grouping, as in “A and (B
or C),” which evaluates differently from the linear “(A and B)
or C.”
Reporting
Click Create Report on the Options screen of the Results window
to compile a report containing all the searches in the Search Results
window. The report is placed on the Report screen, from which you
can print it or save it to disk.
F. Table Utility
One of the primary goals of Clinical Pharmacology is to utilize the
information it contains in valuable ways. The Table Utility allows
you to tabulate and analyze the data you have entered about your
patients in order to help you identify trends in your practice.
Whereas the Patient Profile is concerned with one patient, Table is
concerned with a subset of your patients which you define.
The Table Utility tabulates the data you have entered in the
Patients and Drug Utilization files in your “DB” directory. These
files, which contain data from the corresponding window within
the program, are tabulated independently for simplicity. Thus there
are two screens–Patients Table and Drug Utilization Table–in the
Table window. When you access the Table Utility from either the
Table Patients or Drug Utilization windows, you will get the screen for
VII - 13
that window. From the Patient Records Index, clicking the Table
button brings up a dialog for you to select which screen you would
like. Since the majority of our example pertains to Drug Utilization,
The first step in creating a table is to define a “key field” which you
will use to select and sort the records to comprise the rows of the
table. In the example, we are studying gentamicin, so “Drug” will
be our key field. Using the Key Field combobox (the combobox in
the upper left of the screen), choose “Drug” from the list of fields in
the Drug Utilization window. When you do this, the program
compiles an alphabetical list of all the entries in the Drug field.
The Report button creates a report of the sorted items and places it
on the Report screen on the Index level. This can be useful when
your goal is, for example, to create a list of your most-frequently
prescribed medications. In this case you have reached an endpoint
just by selecting and sorting the records. Usually, though, you will
want to create a table by including some related data from the
selected records.
Define the columns for your table by choosing fields with the
Column Field combobox (the lower-left combobox). The sorted
items from the key field are represented as “Sorted [name of key
field]” at the top of the list. Usually, you will place this item in the
leftmost column, although it can go anywhere. When you choose a
field, its name appears in the box to the right of the button, and you
simply “drag and drop” the field into the column of your choice in
the table template at the bottom of the screen. You can also rear-
range existing columns within the template by dragging them. You
can eliminate a field from the table by dragging it to the Column
Field combobox.
When you drop the “Sorted” item into the table template, the Show
Table and Export Table buttons become enabled (indicative of the
fact that you cannot build a table until you have selected and sorted
items from the key field). Note that at the same time, the Key Field
combobox is disabled. This happens because only one set of records
can be sorted at once. To choose another key field, simply drag the
“Sorted” item to the Column Field combobox.
When the columns are defined and arranged, click Show Table.
Shortly you will see the table, filled in with data from your data-
base records. You can adjust the column separators to change the
width of the columns by dragging them; this can improve the
visibility of the data. You can view the entire contents of any cell in
a popup window by right-clicking on the cell.
Click Export Table to write the table, delimited by tabs and returns,
to a text file which can be opened with a spreadsheet program.
Note that any return characters within the data are replaced with
“◊” (ASCII 215).
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Index
Adverse Reactions
Additive Adverse Reactions Report
non-patient-specific IV-9
patient-specific VII-2
Field V-3
Index IV-9
Window V-4
Allergies
Adding VI-3
Modifying VI-5
Alphabetical Index III-2, IV-5
Arrows
Before standardized terms I-4
Backing Up
Backup Database button III-7
Backup database upon quitting option III-6
Balloon Help IV-4, V-9
Brand names V-1
Bullets
Before standardized terms I-4
Buttons
As objects I-3
Description
Field V-2
Disable save to disk option III-6
Discontinued Products
Index IV-8
Dosage
Window V-3
Drug Indications/Medical Conditions Match VII-3
Drug Interactions
Field V-3
Index IV-8
Report
non-patient-specific IV-9
patient-specific VII-2
Window V-3
Drug Utilization
In prescription processing VI-16
Window VI-8
Drug/Allergy Warnings
In patient profile VII-4
In prescription processing VI-16
Drug/Contraindication Warnings
In patient profile VII-4
In prescription processing VI-16
Renal impairment recommendations VI-16
Fields
As objects I-3
Finding
On Index level IV-1
On Monographs level V-6
Results window IV-2, V-8
Show Find on entry to Index level option III-6
Importing
Patient records IV-11
Index level IV-1
Returning to V-9
Indications
Field V-2
Index IV-8
Installation II-1
Intravenous Admixtures
Report
using admixtures tables IV-8, VII-5
using utility VII-5
Intravenous Products
Index IV-7
Introduction I-1
New Drugs
Index IV-6
Mini-monographs IV-6
Nutritional Products
Index IV-6
Mini-monographs IV-6
Objects
In object-oriented environment I-2
OBRA
Field V-4
Outcome
In Drug utilization VI-10
Overview
Index IV-11
Window V-5
Record number
Modifying VI-5
Record-locking VI-1, VI-5
References
Index IV-13
Locating in monographs IV-13
Registration II-2
Report
Saving to disk IV-13
Screen IV-12
Require password for access to Configure screen opt III-5
Require user code option III-3, III-5
Revision date V-5
Screens
As objects I-3
Show splash screen at startup option III-6
Showing more text V-2, V-6
Showing pictures V-6
Squares
Before standardized terms I-4
Standardized terms I-4
Highlighting and requesting more information I-4, IV-3
System requirements II-1