HH5.

3 (SKIN) HUMAN HISTOLOGY BMLS 2

SKIN

 The outer covering of the body

 The largest organ-system
 Integumentary System
 A set of organs and structures that forms the external
covering of the whole body
 Guards the underlying muscles, bone, ligaments
(Hypodermis)
 The first line of defense against pathogenic
microorganism as the presence of normal flora of our

EPIDERMIS/APPENDAGES

skin
 A sense organ
 Skin cells are more epithelium

COMPOSITION
 Epidermis - epithelium (stratified squamous epithelium,
keratinized)
 Dermis - connective tissue (dense irregular connective
tissue)
 Hypodermis - connective tissue (adipocytes and \
irregular connective tissue)

- Above is the composition of the cross section of the skin.

 Epidermis is made up of 5 layers:
1. Stratum corneum
2. Stratum lucidum
3. Stratum granulosum
4. Stratum spinosum
5. Stratum basale
- Stratum spinosum and stratum basale are considered as
stratum germinativum, here are cells are still active in
mitosis
 The dermis is composed of 2 layer or regions;
1. Papillary region
2. Reticular region
 Hypodermis;
1. Adipose tissue
2. Areolar connective tissue
HH5.3 (SKIN) HUMAN HISTOLOGY BMLS 2