PMID- 19503978

OWN - NLM
STAT- MEDLINE
DCOM- 20090827
LR - 20220310
IS - 1806-4841 (Electronic)
IS - 0365-0596 (Linking)
VI - 84
IP - 2
DP - 2009 Mar-Apr
TI - Autoimmune bullous dermatoses.
PG - 111-24
LID - S0365-05962009000200003 [pii]
AB - Autoimmune bullous dermatoses are diseases in which blisters and vesicles are
the
primary and fundamental types of skin lesion. Their classification is based
on
the location of the blister: intraepidermal and subepidermal. Patients
produce
autoantibodies against self-specific structures of the skin detectable by
immunofluorescence techniques, immunoblotting and ELISA. Recent advances in
molecular and cellular biology have brought to knowledge these self-antigens,
against which patients are sensitized, and which are found in epidermis or in
the
dermo-epidermal junction. These are low incidence, but high morbidity
diseases
that may be fatal. The aim of this article is to review and describe the
progress
of four autoimmune vesiculobullous disorders: endemic pemphigus foliaceous
(wild
fire), pemphigus vulgaris, bullous pemphigoid and dermatitis herpetiformis.
FAU - Cunha, Paulo R
AU - Cunha PR
AD - Faculdade de Medicina de Jundiaí, Brasil. drpaulocunha@bol.com.br
FAU - Barraviera, Silvia Regina C S
AU - Barraviera SR
LA - eng
LA - por
PT - Journal Article
PT - Review
PL - Spain
TA - An Bras Dermatol
JT - Anais brasileiros de dermatologia
JID - 0067662
RN - 0 (Autoantibodies)
RN - 0 (Autoantigens)
SB - IM
MH - Autoantibodies/immunology
MH - Autoantigens/immunology
MH - Autoimmune Diseases/*immunology/*pathology/therapy
MH - Dermatitis Herpetiformis/immunology/pathology/therapy
MH - Enzyme-Linked Immunosorbent Assay
MH - Fluorescent Antibody Technique
MH - Humans
MH - Immunoblotting
MH - Pemphigoid, Bullous/immunology/pathology/therapy
MH - Pemphigus/immunology/pathology/therapy
MH - Skin Diseases, Vesiculobullous/*immunology/*pathology/therapy
RF - 74
EDAT- 2009/06/09 09:00
MHDA- 2009/08/28 09:00
CRDT- 2009/06/09 09:00
PHST- 2008/12/19 00:00 [received]
PHST- 2008/12/19 00:00 [accepted]
PHST- 2009/06/09 09:00 [entrez]
PHST- 2009/06/09 09:00 [pubmed]
PHST- 2009/08/28 09:00 [medline]
AID - S0365-05962009000200003 [pii]
AID - 10.1590/s0365-05962009000200003 [doi]
PST - ppublish
SO - An Bras Dermatol. 2009 Mar-Apr;84(2):111-24. doi:
10.1590/s0365-05962009000200003.