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BACKGROUND
INTRODUCTION
In 1950, Sengstaken and Blakemore developed and described
Managing patients with acute gastrointestinal bleeding from the use of a double-balloon device to control variceal hemor-
gastroesophageal varices can be one of the most challenging rhage.9,10 Since that time, the Sengstaken-Blakemore tube (Video
scenarios in emergency medicine. These patients often have 41.1) has become the most widely known balloon tamponade
advanced liver disease and can arrive at the emergency depart- device. The Sengstaken-Blakemore tube has an esophageal
ment (ED) with massive hematemesis, airway compromise, and a gastric balloon, along with a gastric aspiration port that
hemodynamic instability, critical anemia, thrombocytopenia, allows continuous suction of stomach contents (Fig. 41.2). In
and coagulopathy. Gastroesophageal varices are the fourth most 1968, Edlich and colleagues, from the University of Minnesota,
common cause of upper gastrointestinal bleeding (UGIB) modified the Sengstaken-Blakemore tube by adding an esopha-
and account for almost 12% of cases (Fig. 41.1).1 In patients geal aspiration port and increasing the capacity of the gastric
with cirrhosis, varices account for up to 80% of cases of balloon.11
UGIB.2,3 In patients with established gastric or esophageal Currently, three balloon tamponade devices are commercially
varices, the annual incidence of acute hemorrhage ranges from available: the Linton-Nachlas, the Sengstaken-Blakemore, and
4% to 15%.2,4 the Minnesota tubes. In contrast to the Sengstaken-Blakemore
Over the past 3 decades, advances in resuscitation, critical and Minnesota tubes, the Linton-Nachlas tube is a single-
care, pharmacology, and endoscopy have significantly reduced balloon device that consists of a gastric balloon and two ports
the mortality rate associated with acute variceal bleeding. In (esophageal and gastric) for aspiration and lavage. Because
fact, mortality rates in patients with acute variceal bleeding placement of these tubes remains a relatively rare procedure,
currently range from 15% to 20%.1,5–7 Despite advances in most hospitals stock only one type of device. Regardless of
management, up to 20% of patients with acute variceal bleeding the type of device, success rates for the control of hemorrhage
fail standard therapy.8 Rescue therapies for this group of patients with balloon tamponade tubes range from 60% to 90%.12
Review Box 41.1 Balloon tamponade of gastroesophageal varices: indications, contraindications, complications, and equipment.
852
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CHAPTER 41 Balloon Tamponade of Gastroesophageal Varices 853
A B
Gastric balloon
Distal Endoscopy by a gastroenterologist remains the “gold
inflation port Depth
markers suction standard” for the diagnosis and treatment of acute variceal
Gastric holes hemorrhage.2 Sclerotherapy and band ligation are the two
aspiration port
endoscopic techniques used to control bleeding esophageal or
gastric varices. Endoscopic band ligation has been shown to
Esophageal balloon
Esophageal be superior to sclerotherapy in initially controlling hemorrhage
inflation port Gastric balloon
balloon and improving survival.19 In fact, endoscopic band ligation is
(≤ 45 mm Hg air) (200–250 mL air) considered the treatment of choice for esophageal varices.2,19,20
Figure 41.2 The Sengstaken-Blakemore (SB) tube. Note that this Balloon tamponade is indicated in unstable patients with
tube does not have esophageal aspiration ports; a nasogastric tube massive hemorrhage in whom endoscopy either cannot be
must be attached to the SB tube to allow esophageal suctioning (see performed or is unsuccessful in controlling the bleeding. Balloon
text for details.) tamponade is also indicated when consultant physicians are
unavailable and pharmacologic therapy with vasoactive agents
has failed to stop the bleeding. In cases in which consultants
are unavailable, balloon tamponade can be used to stabilize a
INDICATIONS patient for transfer to another institution with the resources
to continue care.
The general management of unstable patients with acute variceal It is important to recognize that balloon tamponade is only
bleeding is described in detail elsewhere. In brief, initial a temporizing measure. Even though success rates in controlling
resuscitation should focus on early endotracheal intubation; the initial hemorrhage are high, up to 50% of patients rebleed
circulatory resuscitation, including blood transfusion and when the device is deflated.21 Although rebleeding rates can
administration of vasoactive agents and antibiotics; and, most be reduced with the concomitant use of vasoactive agents,
importantly, early endoscopy. Vasoactive agents should be given arrangements must be made for more definitive control of
as soon as possible in cases of confirmed or suspected variceal varices in patients with a balloon tamponade device in place.
hemorrhage. Vasoactive medications reduce portal pressure
and have been shown to decrease or stop variceal bleeding.13–18
Somatostatin and its synthetic analogue octreotide decrease CONTRAINDICATIONS
release of the vasodilator hormone glucagon, thereby indirectly
resulting in splanchnic vasoconstriction and reduced portal Because gastroesophageal balloon tamponade devices are
blood flow. Vasopressin and its synthetic analogue terlipressin typically placed as a final attempt to control hemorrhage and
are direct vasoconstrictors and can be given systemically or prevent imminent death, contraindications to the device are
locally during angiography. These two medications, however, few. They are limited primarily to conditions that predispose
can cause significant coronary, cerebral, and splanchnic ischemia patients to esophageal rupture with balloon inflation and include
and are typically used in patients who fail somatostatin or a history of esophageal stricture and recent esophageal or gastric
octreotide therapy. surgery.
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854 SECTION VII Gastrointestinal Procedures
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CHAPTER 41 Balloon Tamponade of Gastroesophageal Varices 855
1 2
Tube
clamp
Plastic
Deflate plug
Test the esophageal and gastric balloons for air leaks, by sub- Fully deflate the esophageal and gastric balloons. Clamp the
merging under water during inflation. If time permits, record inflation ports with a tube clamp, or insert the plastic plugs
pressures during gastric balloon inflation (see text for details). supplied with the tube into the tube lumen. Lubricate the tube
and balloons with water-soluble jelly.
3 4
SB tube
Silk sutures
NG tube 3 cm
Deflated
esophageal
balloon
Construct a makeshift esophageal aspiration port by securing a Pass the tube orally (preferred) or nasally, to at least the 50-cm
standard NG tube to the SB tube with silk sutures. The distal tip mark, or to the maximum depth allowed by the tube.
of the NG tube should be 3 cm proximal to the esophageal
balloon.
5 6 Inflate 50 mL of air
Gastric inflation
port
Suction
After the tube is fully inserted, apply continuous suction to the Inflate the gastric balloon with 50 mL of air and obtain a chest
gastric and esophageal aspiration ports. radiograph to confirm the position of the gastric balloon below
the diaphragm.
Figure 41.3 Balloon tamponade of gastroesophageal varices with the Sengstaken-Blakemore (SB)
tube. NG, Nasogastric.
Continued
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856 SECTION VII Gastrointestinal Procedures
7 Manometer
8
Gastric
port
Y-tube
connector
Connect a manometer to the gastric inflation port via the Y-tube. When the gastric balloon is fully inflated, clamp the gastric inflation
Inflate the gastric balloon to the recommended total volume in port. Note that bare metal hemostats should not be used, as they
100-mL increments. Compare pressure at each 100-mL increment may damage the tube. Cover the clamping surfaces with cut pieces
to values obtained during testing. High pressures suggest the of red rubber tubing or tape (arrow).
gastric balloon has migrated into the esophagus. (See text for
details).
9 10
Esophageal suction
(via attached NG tube)
Upward
traction
Gastric suction
(via gastric port)
Slowly pull back the device until resistance is encountered. Apply After traction is applied, continuously suction the gastric
continuous traction to the tube. (See text and Fig. 41.6). aspiration port and the attached NG tube which is in the
esophagus. If blood is obtained from either source, then
esophageal balloon inflation is required.
11 Bulb 12
Recommended
inflator maximum 45 mm Hg
Esophageal
port
Y-tube
Inflate the esophageal balloon using the same configuration as in Once hemostasis is achieved, clamp the esophageal inflation
step 7. In general, do not inflate the balloon > 45 mm Hg (see text). port to prevent air leaks.
The use of a bulb inflator is helpful for this step.
Mucosal ulceration from direct pressure of the balloons decrease the pressure in the esophageal balloon by approximately
can occur within just a few hours after tube placement. Accord- 5 mm Hg every 3 hours until a pressure of 25 mm Hg is
ingly, examine the tube, nares, mouth, tongue, and lips fre- reached. Regardless of the pressure, periodically deflate the
quently, and monitor esophageal balloon pressure periodically. esophageal balloon for several minutes every 5 to 6 hours to
Once the bleeding has been controlled for several hours, decrease the incidence of mucosal ischemia and necrosis. Once
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CHAPTER 41 Balloon Tamponade of Gastroesophageal Varices 857
A
Hanging
IV pole
Traction
Sengstaken-
Blakemore tube
B
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858 SECTION VII Gastrointestinal Procedures
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CHAPTER 41 Balloon Tamponade of Gastroesophageal Varices 858.e1
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