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"Neurotransmitter Transporters in Health and
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an Open Access Journal by MDPI
Neurotransmitter Transporters in Health and Disease
Guest Editors:
Dr. Sonja Sucic
sonja.sucic@meduniwien.ac.at
Dr. Lynette C. Daws
daws@uthscsa.edu
Dr. Ameya Sanjay Kasture
ameya_kasture@univie.ac.at
Dr. Shreyas Bhat
shreyas.bhat@umontreal.ca
Deadline for manuscript
submissions:
31 October 2022
mdpi.com/si/76790
IMPACT
FACTOR
6.600
Message from the Guest Editors
Dear Colleagues,
Neurotransmitter transporters (NTTs) belong to the
superfamily of solute carrier (SLC) membrane transporters.
These versatile proteins play a central role in controlling
neurotransmission, by mediating the rapid reuptake of
neurotransmitters from the synaptic cle into neuronal
and glial cells. Over the last decade, ample reports in the
literature have directly linked genetic mutations in NTTs to
diseases including Parkinson´s/dystonia, ataxia, epilepsy,
mental and intellectual disability, and disorders of the
auditory, visual, and muscular systems. Some of these NTT
disease variants trigger folding and trafficking defects,
whereas others alter transporter structure, impairing the
binding, and/or translocation of endogenous substrates. In
this Special Issue, we place particular emphasis on the
molecular basis of NTTs in disease, from the atomic level
to studies in animal models, and recent discoveries
shedding light on novel targets that may incite the
development of effective therapeutic strategies.
Dr. Sonja Sucic
Dr. Lyn Daws
Guest Editors
Dr. Ameya Sanjay Kasture
Dr. Shreyas Bhat
Co-Guest Editors
Special
Issue