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ORIGINAL ARTICLE

Pattern of maxillary and mandibular


proximal enamel thickness at the contact area
of the permanent dentition from first molar
to first molar
Rachel Sarig,a Alexander D. Vardimon,b Celine Sussan,c Lea Benny,d Ofer Sarne,d Israel Hershkovitz,e
and Nir Shpackf
Tel Aviv, Israel

Introduction: Proximal enamel thickness (PET) at the mesial and distal contact areas of the complete permanent
dentition has not been previously reported. Anatomic investigation of PET is essential for interproximal reduction
treatment. Our objectives were to measure the PETs of the complete maxillary and mandibular dentitions at the
contact areas, to compare the PETs of adjacent teeth, and to evaluate the vertical position of each contact area.
Methods: We evaluated 720 extracted teeth; of these, 109 intact teeth were selected. The mesial and distal con-
tact areas were demarcated, and each tooth was embedded in transparent epoxy resin. Blocks were prepared so
that the 2 demarcated contact areas were exposed, and 6 measurements were taken and statistically analyzed.
Results: Both jaws showed the same PET pattern characterized by 5 features: PET increased progressively
from incisor (0.63 mm) to first molar (1.48 mm). Per tooth, mesial and distal PET did not differ. Total maxillary
(26.86 mm) and mandibular (24.52 mm) PETs were similar. Paired PETs at the interproximal interface were
similar, with the exception of the lateral incisor-canine interfaces. From incisor to first molar, the contact area
becomes located farther gingivally. Conclusions: The existing guideline of maximal 0.5-mm interproximal
reduction per 2 adjacent teeth should be kept in the anterior region and could be increased to 1 mm in the
posterior region, when an equal amount is removed. (Am J Orthod Dentofacial Orthop 2015;147:435-44)

D
From Tel Aviv University, Tel Aviv, Israel.
a
Lecturer, Department of Orthodontics, the Maurice and Gabriela Goldschleger ental crowding is a common characteristic of
School of Dental Medicine; Dan David Center for Human Evolution and Bio- malocclusion, defined as a discrepancy between
history, the Steinhardt Museum of Natural History and National Research Center.
b
Professor, Department of Orthodontics, the Maurice and Gabriela Goldschleger tooth size and arch length.1 Although crowding
School of Dental Medicine. may occur in the anterior or posterior region of each
c
Formerly, resident, Department of Orthodontics, the Maurice and Gabriela Gold- arch, adults are most likely to have crowding in the
schleger School of Dental Medicine.
d
Instructor, Department of Orthodontics, the Maurice and Gabriela Goldschleger mandibular anterior region.2 Late anterior crowding is
School of Dental Medicine. considered to be a normal physiologic phenomenon in
e
Professsor, Department of Anatomy and Anthropology, the Sackler Faculty of which a developmental reduction in arch length causes
Medicine; Dan David Center for Human Evolution and Biohistory, the Steinhardt
Museum of Natural History and National Research Center. increased crowding.3
f
Chair, Department of Orthodontics, the Maurice and Gabriela Goldschleger As oral esthetic demands become more exacting,
School of Dental Medicine. resolving dental crowding has become a common
Rachel Sarig and Alexander D. Vardimon are joint first authors and contributed
equally to this work. complaint, especially among adult patients. Furthermore,
All authors have completed and submitted the ICMJE Form for Disclosure of Po- this condition makes it difficult to maintain oral hygiene
tential Conflicts of interest and none were reported. and gingival health.4 Also, it may compromise the
Based on a thesis submitted by Celine Sussan in partial fulfillment of the require-
ments for a master in orthodontics degree at Tel Aviv University. esthetics and functionality of prosthetic rehabilitation.
Partially supported by a research grant from Align Technology, San Jose, Calif. In orthodontics, the patient-driven trend demanding
Address correspondence to: Rachel Sarig, Department of Orthodontics, the faster treatment, with minor interventions, has margin-
Maurice and Gabriela Goldschleger School of Dental Medicine, Department of
Anatomy and Anthropology, Sackler School of Medicine, Faculty of Medicine, alized extraction-based therapy to use in only severe
Tel Aviv University, Tel Aviv 69978, Israel; e-mail, sarigrac@post.tau.ac.il. malocclusions. The technique of removing tooth mate-
Submitted, March 2014; revised and accepted, November 2014. rial by reducing the thickness of interproximal enamel
0889-5406/$36.00
Copyright Ó 2015 by the American Association of Orthodontists. has come into use when the amount of space required
http://dx.doi.org/10.1016/j.ajodo.2014.11.026 to resolve an orthodontic problem is not extreme. This
435
436 Sarig et al

is commonly referred to as “interproximal reduction.” interproximal reduction for the intact dentition should
The principle of interproximal reduction is to partially follow 3 guidelines: leaving a thin layer of enamel,
reduce the enamel layer and consequently the mesiodis- removing more enamel from teeth with greater PET,
tal tooth size without affecting the dentin. This tech- and performing selective reduction at the 2 contact
nique was first described by Ballard5 in 1944 and was areas between paired adjacent teeth. “Selective
primarily dedicated to the treatment of mild or moderate reduction” refers to greater reduction at the contact
crowding. It is based on the natural phenomenon of area with greater PET. However, these guidelines cannot
physiologic interproximal wear and allows the fitting be implemented precisely because of lack of data.
of the dental units to the arches. The major advantage To make up for these deficiencies, the objectives of
of interproximal reduction is that a precise amount of this study were to map the PET of the complete maxillary
space is created to unravel the crowding, as opposed and mandibular dentitions at the contact areas, to
to tooth extraction, which often results in more space compare the PET of 2 adjacent contact areas (ie, the
than required to resolve the dental crowding. distal contact area of the anterior tooth and the mesial
Incomplete enamel removal raises 2 major questions: contact area of the adjacent posterior tooth), and to
what is the minimal enamel layer necessary after inter- evaluate each contact area in relation to the vertical
proximal reduction to protect the dentin layer, and dimension of the crown. Four null hypotheses were
how much enamel thickness is available in different postulated in this study: (1) the PETs are similar per
dental units? Regarding the former, in a long-term arch between teeth and between sides (mesial vs distal),
study, 10 years after interproximal reduction to the (2) maxillary and mandibular PETs share a similar
mandibular incisors, the treated teeth demonstrated no pattern, (3) adjacent contact areas of paired teeth have
increases in sensitivity or in the distance between the the same amount of PET, and (4) the contact area is
roots.6 However, there are no reports comparing the located in all teeth at the same distance from the cemen-
sensitivity of varying thicknesses of residual layers of toenamel junction or the occlusal plane.
enamel after interproximal reduction. There are, howev-
er, 4 indirect indicators that suggest that even a thin
layer of enamel can provide adequate protection of the MATERIAL AND METHODS
underlying tissues: (1) the enamel thickness adjacent We obtained 720 extracted permanent teeth from the
to the cementoenamel junction of the labial crown sur- Department of Maxillofacial Surgery at Tel Aviv Univer-
face of the maxillary anterior teeth is normally about sity in Israel. Upon examination using a Toolmakers
13 mm7,8; (2) occlusal attrition is frequently associated microscope (Mitutoyo, Tokyo, Japan), we excluded 611
with exposure of the dentin layer with no evidence of because of peripheral preparations, proximal restora-
sensitivity; (3) dentinal reaction to enamel reduction is tions, or extensive proximal loss (ie, interproximal wear
characterized by occluded dentinal tubules; and (4) facet spread buccolingually to the edges of the proximal
additional dentinal reaction is in the form of buildup wall), or impaired proximal walls during extraction
of secondary dentin.9 (proximal wall scratched or damaged). Therefore, 109
Interproximal reduction was developed further by (59 maxillary, 50 mandibular) intact teeth were included
Sheridan.10 Several studies have reported on proximal in the study (Fig 1); 48 (44%) of these teeth were derived
enamel thickness (PET) on posterior11-14 and anterior from male subjects and 61 (56%) from female subjects.
dentitions.7,15-17 Macha et al11 and Fernandes et al12 All were of white ethnicity. The mean age of the subjects
suggested a strong right-left symmetry for the same was 34.3 6 10.3 years, with a range from 12 to 59 years.
contralateral teeth, but their analyses were based only The teeth, which were stored in 8% formaldehyde
on the maxillary first and second premolars. Right-left (Bio Lab, Jerusalem, Israel), were rinsed in water (3 hours)
symmetry from incisors to premolars was also found and dehydrated in ascending ethanol concentrations
by Vellini-Ferreira et al.18 Stroud et al15 suggested, (40%, 70%, 95%, and 100%) every 2 hours, and then
based on bitewing measurements, that PET increases to- placed in Xylen (Bio Lab) for an additional 2 hours.
ward the distal aspect in the mandibular posterior denti- Each tooth was then classified according to type, jaw,
tion except for the second premolar, with no sex and side, and the mesial and distal contact areas were
dimorphism. demarcated with red and blue markers, respectively.
Currently, orthodontic interproximal reduction is The identification of the contact area was based on dif-
limited to 0.5 mm per interproximal region, about ferential brightness of the enamel during wear. That is,
0.25 mm from each of the 2 teeth.4,5,10 The technique is the proximal facet in the contact area may appear as a
based on removing enamel from the proximal wall polished surface or a bright plain area,19 according to
starting at the contact area. The principle of orthodontic the method described by Sarig et al.20

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Sarig et al 437

Fig 1. The 109 teeth used in the study divided by type and jaw. Central incisor, I1; lateral incisor, I2;
canine, C; first premolar, P1; second premolar, P2; first molar, M1.

Fig 2. Schematic drawing illustrating the sectioning process. A, Block before sectioning. The block
was bisected parallel but 2 mm away from the contact area plane, producing 2 unequal portions. B,
The portion including the 2 demarcated contact areas was then trimmed to the point where the mesial
contact area (red) was exposed (red arrows, exposed surface). C, Trimming was continued until the
distal contact area (blue) was also exposed, and the exposed surface was then polished (red arrows,
exposed surface).

Each tooth was positioned vertically in a 20-mL vial enamel on a plane where the 2 contact areas were present,
with the long axis parallel to the long axis of the vial using the sectioning was carried out in 2 steps (Fig 2). First, us-
molding paste at the bottom of the vial. Subsequently, ing an apparatus for microstructural analysis (Isomet low
each tooth was embedded in transparent epoxy resin speed saw; Buehler, Lake Bluff, Ill), each tooth was bi-
(Polysciences, Warrington, Pa). After curing, the block sected parallel to but 2 mm away from the contact area
was sectioned. Since the purpose was to measure the plane, producing 2 unequal portions (Fig 2, A and B).

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438 Sarig et al

Second, the portion including the 2 demarcated contact


areas was then trimmed (Single Wheel Orthodontic Model
Trimmers; Wehmer, Lombard, Ill) up to the point where
both the mesial and distal contact areas were part of
the exposed surface (Fig 2, C). The exposed surface was
then polished (Ecomet, variable speed grinder-polisher;
Buehler) using P320 and P120 waterproof abrasive paper
(WS flex 18-G; Hermes Schliefmittel, Hamburg,
Germany). Six measurements were made on each tooth
with the Toolmakers microscope with a closed camera
and a monitor (Koyo Electronics Industries, Tokyo Japan)
at 10-times magnification. The measurements included
the following (Fig 3).
1. Mesial proximal enamel thickness (PETM), the
distance from the midmesial contact area to the
dentinoenamel junction (measured on a line
parallel to the long axis of the tooth passing through
the contact area).
2. Distal proximal enamel thickness (PETD), the
distance from the middistal contact area to the
dentinoenamel junction (measured on a line parallel
to the long axis of the tooth passing through the
contact area).
3. Mesial contact area to occlusal plane (CAM-OP), the
distance from the midmesial contact area to the
occlusal highest point on the mesial side (measured
on a line parallel to the long axis of the tooth pass-
ing through the contact area).
4. Mesial contact area to the cementoenamel junction
(CAM-CEJ), the distance from the midmesial contact
area to the mesial cementoenamel junction
(measured on a line parallel to the long axis of the
tooth passing through the contact area).
5. Distal contact area to occlusal plane (CAD-OP), the
distance from the middistal contact area to the
occlusal highest point on the distal side (measured Fig 3. A, Longitudinal cross section of a molar through
the mesial (red arrow) and distal (blue arrow) contact
on a line parallel to the long axis of the tooth pass-
areas. B, Schematic illustration of the 6 measurements:
ing through the contact area). proximal enamel thickness mesial (PETM), proximal
6. Distal contact area to cementoenamel junction enamel thickness distal (PETD), contact area (CA) to
(CAD-CEJ), the distance from the middistal contact occlusal plane (OP) on the mesial (CAM-OP) and distal
area to the distal cementoenamel junction (CAD-OP) sides, CA to cementoenamel junction (CEJ)
(measured on a line parallel to the long axis of the on the mesial (CAM-CEJ) and distal (CAD-CEJ) sides.
tooth passing through the contact area).
intratester and intertester tests were 0.93 and 0.91,
Statistical analysis respectively. Statistical analysis was carried out with
The intraclass correlation coefficient was calculated SPSS software (version 18.0; SPSS, Chicago, Ill). Data
to determine the intratester and intertester reliabilities analysis was carried out using t test analysis and 1-
of the measurements (repeated measurements of 10 way analysis of variance with post hoc analysis (Tukey
teeth). Intratester reliability was assessed by 1 investi- B). The level of significance was set at P \0.05. No
gator (C.S.), and intertester reliability involved 2 testers significant difference was found between the sexes
(C.S., R.S.). The testers were unaware of each other's re- regarding PET (the lowest nonsignificant P value was
sults. The intraclass correlation coefficient values for the in the maxillary canine, P 5 0.329, on the distal side);

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Sarig et al 439

Table. Proximal enamel thickness (PET) in the mesial (PETM ) and distal (PETD ) sides according to tooth type and jaw
Comparison of tooth types

Tooth PETM (mm) PETD (mm) PETM vs PETD (P value) PETM (Tukey B) PETD (Tukey B)
Maxilla
I1 0.81 6 0.06 0.81 6 0.27 0.998 I1, I2, s M1, P1, I1, I2, C s P1, P2, M1
C, P1 s P2 P #0.01
P #0.01
I2 0.76 6 0.14 0.86 6 0.28 0.206
C 1.10 6 0.21 1.11 6 0.26 0.747
P1 1.13 6 0.15 1.25 6 0.37 0.593
P2 1.41 6 0.27 1.36 6 0.30 0.652
M1 1.35 6 0.29 1.48 6 0.17 0.137
Mandible
I1 and I2 0.64 6 0.19 0.60 6 0.18 0.581 I1, I2 s C s P1, P2 I1, I2 s C, P1, P2, M1
P1 s M1 P #0.01
P #0.01
C 0.97 6 0.21 1.30 6 0.61 0.133
P1 1.16 6 0.13 1.05 6 0.24 0.227
P2 1.23 6 0.10 1.30 6 0.20 0.305
M1 1.37 6 0.12 1.40 6 0.20 0.720

I1, Central incisor; I2, lateral incisor; C, canine; P1, first premolar; P2, second premolar; M1, first molar.

therefore, the teeth of both sexes were used in all statis- the molars. Posteriorly, only the first premolar exhibited
tical analyses. significantly reduced enamel compared with the first
molar (P\0.01). On the distal contact area, a significant
difference in PET was found between the incisors and
RESULTS the canines, premolars, and first molars (Table).
Categorizing the contact area of the maxillary denti- In relation to both jaws, only the incisor group
tion according to PET greater than or less than 1 mm, we showed a significant difference between the jaws, pre-
found that the central and lateral incisors demonstrated senting greater PET in the maxilla.
PETs of less than 1 mm on both the mesial and distal con- The interproximal interface of neighboring teeth
tact areas, and that the canine, the first and second pre- comprises 2 opposing proximal walls of the 2 adjacent
molars, and the first molar had PET greater than 1 mm on teeth, ie, the distal proximal wall of the anterior tooth
both the mesial and distal contact areas. The mesial PETs and the mesial proximal wall of the posterior tooth. In
for the canine and the first premolar were significantly the maxilla, the sum of the 2 PETs ranged from
less than those of the second premolar (P \0.01). PET 1.57 mm between the central and lateral incisors to
of the second premolar did not statistically differ from 2.71 mm between the second premolar and the first
that of the first molar. Additionally, the second premolar molar. In the mandible, the sum ranged from 1.23 mm
had the greatest PET (1.41 6 0.27 mm) at the mesial con- between the right and left lateral incisors to 2.67 mm be-
tact area (Table). As for the distal side, PETs of the lateral tween first premolar and the first molar. A difference be-
incisor and the canine differed significantly from those of tween paired adjacent PETs was found only between the
the first and second premolars and the first molar lateral incisor and the canine for both the maxillary arch
(P \0.01) (Table). (P 5 0.039) and the mandibular arch (P\0.001). In both
Dividing the mandibular dentition as above, we cases, the mesial PET of the canine was significantly
found that the lateral incisor on both the mesial and greater than the distal PET of the lateral incisor (Fig 4).
distal contact areas and the canine on the mesial side For the vertical positions of the contact areas, the
demonstrated PETs less than 1 mm. All other teeth greatest distances of CA-OP were on the distal side of
(canine on the distal side, first and second premolars the canine in the maxillary (4.5 mm) and mandibular
and first molar on the mesial and distal contact areas) (3 mm) arches. The smallest CA-OP values were found
showed PETs greater than 1 mm. At the mesial contact on the mesial side of the maxillary first premolar
area, the PET of each tooth type differed from the (2 mm) and the mesial side of the mandibular lateral
others, resulting in 4 significantly different groups: in- incisor (1.5 mm). The distances of CA-CEJ were the
cisors, canines, premolars, and first molars. A gradual greatest on the mesial side of the central incisors in
increase in mesial PET was seen from the incisors to the maxillary (5.2 mm) and mandibular (6.2 mm) arches,

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440 Sarig et al

A
Maxilla
3.5

proximal enamel thickness (mm)


2.5
*
2

1.5 Distal tooth


Mesial tooth
1

0.5

0
I1-I2 I2-C C-P1 P1-P2 P2-M1
*p<0.05 paired adjacent teeth

B Mandible
3.5
proximal enamel thickness (mm)

2.5

2 *
Distal tooth
1.5
Mesial tooth
1

0.5

0
I1-I2 I2-C C-P1 P1-P2 P2-M1
paired adjacent teeth
*p<0.05

Fig 4. Comparison of PETs of adjacent paired teeth: A, maxillary dental arch; B, mandibular dental arch.

and the lowest were on the distal sides of the first premo- the study sample was based on our study and previous
lar in the maxillary (3.4 mm) and mandibular (3.4 mm) studies that found no sexual dimorphism in PET.17,23,24
arches (Fig 5). Generally, the contact area was located The PETs of the anterior teeth in both jaws differed
closer to the cementoenamel junction in the posterior significantly from the rest of the teeth. This diversity by
than in the anterior dentition (Fig 5). type of tooth occurred on both the mesial and distal sides.
Thus, the null hypothesis that PET in all teeth is uniform
DISCUSSION was rejected. On the other hand, this study confirmed the
Although the age range of the sample was 12 to null hypothesis that mesial and distal PETs for an individ-
59 years, there was a lack of influence of age on enamel ual tooth were similar. This does not agree with previous
thickness, since enamel formation of the permanent studies.11,12,15 However, this might be explained by the
dentition up to the first molar is completed by the age differences in the methodologies used. In our study, the
of 3.0 to 3.3 years.21 However, reductions in enamel enamel thickness was measured directly histologically at
thickness take place especially after the age of 50.22 the mesial and distal contact areas, whereas Macha
For this reason, 95% of the teeth in our sample were et al11 and Fernandes et al12 investigated only the greatest
below this age limit (mean age, 34.3 6 10.3 years). thickness of enamel, and Stroud et al15 investigated this
Moreover, teeth with severe proximal wear were radiographically.
excluded from the study; since normal wear was taken Maxillary incisors and canines were found to have
into account, this suggests that our data were skewed significantly thinner enamel than premolars and molars.
to the thin range of PET. The merging of both sexes in In the mandible, only the incisors had significantly

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Sarig et al 441

Fig 5. The vertical position of the contact area was defined by the distances of contact area to cemen-
toenamel junction (CAM-CEJ, CAD-CEJ) and contact area to the occlusal plane (CAM-OP, CAD-OP) for
each tooth in A, the maxillary dental arch; and B, the mandibular dental arch. m, Mesial; d, distal.

thinner contact area enamel than did the rest of the arch. interproximal enamel thicknesses, 68.27% and 95.45%
In both jaws, no differences were found between the of PET measurements lie within 1 or 2 SDs from the
molar and the premolar groups. Only between the maxil- mean, respectively (3 sigma rule). Therefore, without an
lary and mandibular incisors was a significant interarch individualized enamel thickness analysis, the limit of
difference in PET found. interproximal reduction should be planned based on
The study confirmed the null hypothesis that the PETs the equation of mean PET of 62 SD. Consequently, if
of adjacent teeth are essentially equal, with the exception equal amounts of enamel are removed from adjacent
of the lateral incisor-canine interface in both arches. This teeth in the anterior region of both dental arches, it is rec-
suggests that when planning interproximal reduction, it ommended that a maximum of 0.5 mm of interproximal
is safe to apply a technique to remove an equal amount reduction be performed. In the posterior region (canine
of enamel from the adjacent proximal walls of both teeth. to first molar), 1 mm of proximal enamel can be removed.
In the lateral incisor-canine interfaces of both arches, Our findings do not support the null hypothesis that
more enamel can be removed from the mesial proximal the vertical distances between the contact areas to the
surface of the canine, since it is significantly greater cementoenamel junction or to the occlusal plane in all
than the distal PET of the lateral incisor. teeth are identical. We found that a progressive migra-
A further aspect to consider is the maximal amount tion of the contact areas in an apical direction from
of interproximal reduction between adjacent teeth anterior to posterior occurred. That is, the contact areas
that can be performed. Given a normal distribution of were closer to the incisal edge in the anterior teeth and

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442 Sarig et al

closer to the proximal midcrown in the posterior teeth. Three strategies should be considered when planning
This finding is consistent with our previous study.25 interproximal reduction to correct an arch length defi-
The location of the contact area is associated with the ciency: (1) anterior interproximal reduction (incisor re-
location of interdental crestal bone,26 periodontal gion), (2) posterior interproximal reduction (canine,
breakdown of the interproximal gingival col,27 inter- premolars, first molar), (3) full interproximal reduction
dental black triangles,28 and malaligned teeth.29 (both anterior and posterior regions).
The vertical position of the contact area provides a Anterior interproximal reduction should be consid-
guideline for interproximal reduction procedures. This ered for oversized incisors (especially maxillary central
should be performed at the contact area to accomplish incisors or mandibular lateral incisors). Anterior inter-
interproximal clearance between 2 adjacent teeth. proximal reduction should be taken into account in
Accordingly, it should be carried out on the occlusal third the case of left-right incisors' size asymmetry,
of the proximal walls of anterior teeth and midcoronally triangle-shaped incisors (shovel shaped), and black tri-
on posterior teeth, ideally at a vertical distance of 5 mm angles. According to this study, maximal space gains
from the base of the contact area to the alveolar crestal of 3.24 mm in the maxillay arch and 2.48 mm in the
height.30 Furthermore, it has been suggested that mandibular arch are available when 50% of the enamel
enlarging the 2 contact areas by interproximal reduction, thickness is preserved. Our findings demonstrate that
creating a flat proximal surface, might reduce the relapse the greatest contact areas to cementoenamel distance
potential compared with a pointed interproximal inter- are on the mesial side of the central incisors in both
face, which is prone to produce overlapped teeth. the maxillary (5.2 mm) and mandibular (6.2 mm) arches.
Such a regimen is particularly recommended for anterior This suggests that performing anterior interproximal
teeth.31 reduction to further displace the contact area gingivally
The null hypothesis regarding the maxillary vs may prevent or counteract black triangles.
mandibular PET relationship is supported by our find- Posterior interproximal reduction should be consid-
ings. Both jaws showed the same pattern of PET, with ered if anterior proportions are normal and no triangular
minor deviations. This similarity is related to 4 character- teeth or black triangles are present. Posterior interprox-
istics. First, the PET of anterior teeth was not found to imal reduction is applicable for mild, moderate, and
exceed 1 mm, and that of posterior teeth was between severe crowding, especially with proximal restorations.
1.10 and 1.48 mm. Consequently, PET increased pro- According to our study, maximal space gains of
gressively along the dental arch from the central incisor 10.19 mm in the maxillay arch and 9.78 mm in the
to the first molar in both arches. mandibular arch are available when 50% of the enamel
Second, the sums of mean enamel thicknesses of the thickness is preserved.
maxillary and mandibular hemiarches (from the mesial Using both anterior and posterior interproximal re-
side of the central incisor to the distal side of the first ductions should be considered for patients with moder-
molar) were not found to be significantly different ate and severe arch length deficiency when anterior
(13.43 mm in the maxilla, 12.26 mm in the mandible). interproximal reduction is favorable but is not sufficient
This suggests that when performing interproximal to unravel the crowding. According to our study,
reduction of 50% in each hemiarch, a space almost equal maximal total space gains of 13.43 mm in the maxillay
to the extraction of 1 premolar becomes available. arch and 12.26 mm in the mandibular arch are available
Third, the adjacent enamel surfaces comprising a when 50% of the enamel thickness is preserved.
contact area were found to be similar, with the exception Although it is beyond the scope of this study, enamel
of the lateral incisor-canine interproximal interface, reduction should be considered in the context of its
where the distal PET of the lateral incisor was signifi- impact on sensitivity and tooth morphology. Zachrisson
cantly less than the mesial PET of the canine. et al6 demonstrated that 10 years after interproximal
Fourth, the vertical location of the contact area was reduction in mandibular anterior teeth, no sensitivity
found to be more occlusal in the anterior teeth and was found in 59 of 61 patients, and there was no in-
farther gingivally in the posterior teeth. crease in caries susceptibility.32 However, temporary
The PET similarity in these 4 characteristics suggests sensitivity might appear immediately after interproximal
that when no Bolton discrepancy is present, the same reduction and should be treated with fluoride varnish,
amount of interproximal enamel should be removed in fluoride mouth rinse, and fluoride gel.33,34
a patient with an Angle Class I relationship. However, a Morphologic changes after interproximal reduction
patient with a Bolton discrepancy, an Angle Class II are related to changes in tooth size and shape of the
malocclusion, or an Angle Class III malocclusion might proximal contact area. Diminished tooth size due to
require dissimilar amounts of interproximal reduction. interproximal reduction is beneficial in attempting to

April 2015  Vol 147  Issue 4 American Journal of Orthodontics and Dentofacial Orthopedics
Sarig et al 443

replace a lateral incisor with a canine,35 but disadvanta- 3. Little RM, Wallen TR, Riedel RA. Stability and relapse of mandib-
geous for already slender teeth such as mandibular inci- ular anterior alignment—first premolar extraction cases treated
by traditional edgewise borthodontics. Am J Orthod 1981;80:
sors.17 Changing the contact point to a contact area
349-64.
between 2 adjacent teeth is beneficial in reducing black 4. El-Mangoury NH, Gaafar SM, Mostafa YA. Mandibular anterior
triangles,30 especially maxillary central incisors.36 Thus, crowding and periodontal disease. Angle Orthod 1987;57:33-8.
interproximal reduction may be apt in addressing ortho- 5. Ballard ML. Asymmetry in tooth size, a factor in the etiology, diag-
dontic issues for patients with triangle-shaped teeth.36 nosis, and treatment of malocclusion. Angle Orthod 1944;14:
67-9.
It has also been reported that root proximity causes
6. Zachrisson BU, Nyøygaard L, Mobarak K. Dental health assessed
an improvement in the interdental papilla.37,38 Root more than 10 years after interproximal enamel reduction of
proximity can occur after interproximal reduction, and mandibular anterior teeth. Am J Orthod Dentofacial Orthop
authors investigating any detrimental effects of this 2007;131:162-9.
did not conclude that this was the case.6 Interproximal 7. Gillings B, Buonocore M. An investigation of enamel thickness in
human lower incisor teeth. J Dent Res 1961;40:105-18.
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CONCLUSIONS Mesiodistal width and proximal enamel thickness of maxillary first
bicuspids. Braz Oral Res 2010;24:58-63.
PET is characterized by the following.
12. Fernandes SA, Vellini-Ferreira F, Scavone-Junior H, Ferreira RI.
1. Similar PET patterns between the 2 dental arches. Crown dimensions and proximal enamel thickness of mandibular
second bicuspids. Braz Oral Res 2011;25:324-30.
2. PETs of anterior teeth did not exceed 1 mm, and
13. Fillion D. Apport de la sculpture amelaire interproximale a
those of posterior teeth was between 1.1 and l’orthodontie de l’adulte. Rev Ortho Dento Faciale 1993;27:
1.5 mm. 189-214.
3. The sums of mean enamel thicknesses from the right 14. Crain G, Sheridan JJ. Susceptibility to caries and periodontal dis-
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15. Stroud JL, English J, Buschang PH. Enamel thickness of posterior
the first molar were 26.86 mm in the maxilla and
dentition: its implications for nonextraction treatment. Angle Or-
24.52 mm in the mandible. thod 1998;68:141-6.
4. The 2 PETs of intra-arch paired adjacent teeth are 16. Tuverson DL. Anterior interocclusal relations: part 1. Am J Orthod
similar, with the exception of the lateral incisor- 1980;78:361-70.
canine interproximal interface in both arches, where 17. Hall NE, Lindauer SJ, T€ ufeki E, Shroff B. Predictors of variation in
mandibular incisor enamel thickness. J Am Dent Assoc 2007;138:
the distal PET of the lateral incisor is significantly
809-15.
less than the mesial PET of the canine. 18. Vellini-Ferreira F, Cotrim-Ferreira FA, Ribeiro JA, Ferreira-
5. The vertical location of the contact area is more Santos RI. Mapping of proximal enamel thickness in permanent
occlusal in the anterior teeth and farther gingivally teeth. Braz J Oral Sci 2012;11:481-5.
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among prehistoric Tennessee Indians: implications for masticatory
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ACKNOWLEDGMENTS 20. Sarig R, Hershkovitz I, Shvalb N, Sella-Tunis T, May H,
Vardimon AD. Proximal attrition facets: morphometric, demo-
graphic, and aging characteristics. Eur J Oral Sci 2014;122:271-8.
We thank the following for their significant contribu- 21. Reid DJ, Dean MC. Variation in modern human enamel formation
tions: Ilana Gelernter, Department of Statistics; Ana times. J Hum Evol 2006;50:329-46.
Bahar, Department of Anatomy and Anthropology; 22. Atsu SS, Aka PS, Kucukesmen HC, Kilicarslan MA, Atakan C. Age-
and Michael Blum and Moshe Davidovitch, Department related changes in tooth enamel as measured by electron micro-
of Orthodontics, all at Tel Aviv University. scopy: implications for porcelain laminate veneers. J Prosthet
Dent 2005;94:336-41.
23. Schwartz GT, Dean MC. Sexual dimorphism in modern human per-
manent teeth. Am J Phys Anthropol 2005;128:312-7.
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