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    Malik Usama Qamar
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    © All Rights Reserved
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    21 views18 pages

    Waqar 203 (Toxicology)

    Uploaded by

    Malik Usama Qamar

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
    Flag for inappropriate content
    of 18
    moa History of teviicnloyyt Bee Certicidas L ahunrn ‘Te Aet 9, Rani _3- Branchos ob Fouicole : Meee Scote ol, Toul coloay b= Cases of Tonicit i 6- Latenc Perrod =e Me (- Phytotouicty ob Resticdors qe Plots 8 Mining of, Pesticides, ((aitive._auaoueae ___ eae Aucte.qo-dsm)) Pract cals Di] fox estimales of tenic eCRel. in Be Celossifietion ok Insecttciday on OATS ‘h) oe AlPed a. lott farts = is “Toutcolo The werd tevieole | gagole words Toulon means Roisoucus _ substance Wwito which orhew Wosds wer Q “toGQas meawing study. | Toriccle§y deal with the study of odiene of chamia substances ou the llving oAgauisms | |due te their enPosurk. La Tewleolefs is a Lietd ch science thok VretPs us 44 Fundsrstand the harms eftecls tak chemleRs, | substances or SttuoRiew, can have en Restle, animals, & the envideonmer® - jell [Aarow Poisons wore davetebed by ancewk Restless ta J | | Modai_ Nulers - (Rose 4228 so 2 Eberr Paryaus (\soo &£) oldest documercR (Geol couttaing lo Poe} om Ahe anatom4, £ lWypioleyy Fevdeo ley y |mediciveQ & Porsonous aacifs ye Aslved from 7 oR oa History of Tonicalogy of Ahe world f mang ors shu la we | & tasetmeck aserded me d aan Diosconidy (uo ~40 0 A.) lohuce Bhysdion Lassified Poisons for nerw. waste the mateiR ‘ et volumes) decimentivg even bee medicinal - Qlarcts he encourtercd while travelli ing with the Amey nilerory, . >| es Swiss Phgcician Paracelsus (1493 - (S40) tre Afaxnd- fathor ok Toni esleyy — He caid Ail substances ort Poison thoAL ts nore which ig net a Poison. the aged ISfereuchia << é zm Poisow frcm a rome dy. 1 eh z as _& Catherine Medici (1519-158) She often wed ; Roig oni es a Relitical acl desig WO Asie she | feerimeted with Poisons on Ake Sick £ Rock Ae | | __ doveteR mort advavced Persons. ne Ty 15th century ww ital Cesah £ lucerrig sors | a Tassassmxted mane olf *Aerr Poittend Avals by Reisen worth ergerre , co Pek £ PhosRherus- 14 Malbiew Orfila (187-1853) Orfila is Acqerded O35 ok modem Fovicolofy because of big © Sr dencad coutribtion Te this subject He lable a Systemoctic comelation betweon the chemles » [bioleJicn Rrokerties of Rorsous. He _ kemong traded | ects ek Pcisons ob “SRecific organs, % analyeiy _ entesals eraals fon P Ration. Ua Name. Sat ory) Faas ee te f si ee __ Tn rath _Cectuny VST See [chemical worfare (\415) by the middle tale? chemi Mod bean daveloded te be wed hg The _militorg or vseatons. Agents such 05 chlorine, | chiorneticrtn, Rhasgere 1 musteord Jos werk oth ; used in ehemico worfard, (Humans & dats wor fitted al 52 |Genhord Schroder (1q03-18%0) Accidatally devela fe tewie newe Herts Sori, Tabum, Soman, 4. Gyele saat while alleg?ting fo devete? new insecticide}. eae o wi e lassult these Foule qosey wart utilized briny ldo, Wer at ba the Narvs, tle is sometimes entlod father of the pen | ze ae g3{Paul_Hamenn Mullec ODT -1939 a | DOT wor secoquirned od nsecticids ~ by the Susiss_ | Scientist Pork Hamann Culler, whe was aw ded ee TRYQ nobel Yaire Aw wWwpioleYy £ Medicine. @ | 09T we banned ta (ate suties en : | seventies lagaliag o 3 ee Poisous Se ‘OAS for Aha daxtancliox of uedon inable: S : sms (uel on Rlads © ott xd Rextic\ dos. j Rit tke Pexttctdar ore classiGed according [te the cate 9° © OG Farid sms OFLo | whtelr RRS Font. re aed ae 2 fee) Ret oRRauisms [ A) Dsecttcidoss Wed fo lil on conan) 2) Rodoutici defy Used to colrel And | a) Acaytados ve Used to courtrel mites on tals fanitn a) tctdoxry Wed +e ackel binds jo gercrdads. Used te | c)Nematicidar, Wed to 11) Fungicidose Used te B) Bactentcider + ured Ao eee soss “ubed fo | lil gwatl £ slugs ; covlrel nematodes e corrtro) Plawk disease Ai volves 1 15 wih Verlous oualyica Teclont 2 Cini cod Jonicalo yy ¥ Deals ort Rrcuertioy MM trssitme4 em Sure Rarsoning Code pForonsic TonicoloA ys deals vvith dhe ewalyls oh asaiee gubdtances which iwwolve various metheds Te Teale the Poisonous sulpstan ces 4e aid the \eqak osoch of iced Tertiolo XY - = phe SRecialized brand of a) Veterinary ‘teuicolo44 : FPHawtcategy wvics deals wit dhe shay , dtegnests — t Ansettment off veottous Conte camPounds Lasse al ja the animal cinydom: ZA p-3)| Food touico lod, Food tonicelogists donk sit the p [BRR Possible Aclelerious efedls off chemtals 34 peed Sor umex consumition (esidua level Deals | wrt ane. Ww Qs en humau 9 a Poisons » Any gubctances the cahes deletorraud « We eee onganisms« i ; Te study ek Peay See the uw = = ee au Pr mibeataass asle tw cout anthinye _| ~ Tynseets Rests ia ahe Leld of eHatcultwrr , Fonsi, £ Cablic healt Toxic chemisls $0 for or the main defense eqaiest | best attactes- cee AR a number es etter wrtrcl mead, wa | Imone of them matt Ww thaik effeacy , sResd, shelly Ig cost of aPeanNions sorte chemicat serdinel messing :| [Fecilitelos the davetetmenk ek NEWLA , Ynovetiwe Te mead selecive dings therntien to tron ae | “feilmets- Terminologies 1) Py Tarr Poisons that onrginate Crom wlologenl Process, [Patsoncus substarce @redteed by o Wine @rgantey, houch Os 4 Rat, animal of micdro- organism cuuneise "7 [ehytetexins, Lostovius, Bactarotorins L My rotoxins « a ial 2) Towico sis © The disense state Ahad avults Aro alos wre to a Reson: ay Kenobicticr A AGA uae aca [ha is Ane beds ov va Quiny onfaniems- Kenes~ strawcge, bios- life) a with fie biolegiend humans 9 Peyticide exPosure ments exticded th eA on the bedy. _5| Do ev the tata amour ok Aenicad “Hfer animal Y called dose- SEL Dose \¢ dole ndov RoR = Conceritredion CroPerties eb Fontan - Timing G Karajnaucy oh eoturd ~ ErRos rer Datlusoys Be a ug E Lengit of Ty Low? - RS et ) Didosare Te omot -b fovcoudt Ror ea Planes weight OS called dogo Qe pil. Rex OUsey The dssyrco ok; nssfonges deRends 2 , dsxe & tke oagadicm: 3 ’ Period TexamPle a smart amourt of emnouia tan cande threat or eye inition edie comPounrds Oecwrds imme diately or Sor after _enPosure (short {atency) Often involves a high ePosure Marge dosejover a short often. Aevasible after enlosurt stels. Cau be minor oh severe. for Hanger amoads can be serious oh even fatal: x Vast Peri Keute Han ts soturnted comPounds . = Comfounds iwi 5 | Period most chemicals have Tee begy duclive effects. double bands, rOocurs over Hme en levg [after enPosurt (long [at (Komal doses} over a lot effects org Awverdible- Man Chrowic effeds ers for many chemicals, fo fasted for cance of oh adtac- |” p dhe aPhearnce of Aisenes “enue leat enfosuve \s cathad the. latent ome chronic etfecls cored by chemics Saal eancer, Wane v wy lon \pher Tees. Cancthy Was seen ACR emery eS oS a a wonlenht 5 ust entoourr NS a cancet > Ari OT Rerefons Haars is VOY oe labor k Tee latency Period of a oe ill A eo effect dleQnosie 88) Beiog SKi for 9 Pye th = a" Q _Riytoteni cay my Te the dente of Ake — ubsle rack eL@ele an cs a OMses of; Phy totonics faker ty allliod dinactly to tee Pad | | | dun, adverse _envirenmertad conditions. ~{A_ Matera} ated Wats t Shot dust or valor drifts trom the al x Lerch Te aA sensitive cape ; - Use. ok Tnsecticide yu (orge amour — = [Residues accumulate in ths get) on Pe Pla. i » Pesticide Toni city aRReo4 A aes wet “agen ‘ & ter of damage mo ie bowie of led CRP, Mersin on eddie Aka Plouts 45 osu “ely a Resficde +. lads the orn shasaste law’ should be YoY at tan oktimum. avoid | ing Modes ertraomels ct, sunny covdttions- PARY ww He moming Tf Roscible. 2- Dew ally Pestiddey under conditions whit nL will not Praomale gy: pee 3- Weltalle Powder ro woually safer Te Plats > dhan aro emulsifiable coucevetactes becosie 7 al Powders do not cwrtalu emulsifiers © solvects- | | p | Contireons eRitefion iu tke she Tanks 1¢ Ge : | MeCess To Rasver® sPraoq materials from seg | out, aaPicially wellable Poudars. 4 sig cteale michat mo} peutt tn Plant ted oes act occur from we of either Tb Ais materia Q alone - (Sotto fa label 56 Almost all Geragat foamuladions of Reshddes att couse thytotondety if aPPlied at \ess tine the _ Accommended distance pelwerm the aerosol no2% [when tiso oA mohe than two tyes © — chomicals ar2 Mined than the following Res of Phenomertou of2 Possible I () Additive Arsforse + When two Pshiads or t mik & the cumulative efGet is eral Ae | the eft ck individual efQet tha this | #5 called Additive rcslorse. aa, &9 Bae et (®) —. cumnulective efed | @) Sfnergisme wheu tive Pesticides ona min |g he cumulatwe eft is opener. Aiea fie ef GK of lndividual efCed called Smorgqism . &) @® e S Gs) — cumulative efed 1 (a) Axtogorisom, wher ioe Rextiddes v2 _ mit q wa cumulative ef@et ig los j fia ehfet ok indisiduod seein : sotto ia (60) — Assignment No. Procheal -4 Dose Estimaten oly Tonic effects Letiad Dose The lowest dose tht cae3 death wn ane animal dariwe the Rerucd of Tobseruation. LDs. +: The amouk of tenia La can ert Soy oh the Texted Poludation unrdeh a defined et ok enlerimer Rak couditten, Where ARR Rerulatior is qeraAtalt homog enoous Hedain \cthad dose (MLD) Eafuivelest Yo the fEDSo. £ cou be ured {uher chan cally a Smaller the LOsc, mone Towle tha cham Gey Grater the LDso, tess fowic the chemlea Q _ ‘Lethal time Qt) v The lowest Aime ak Wit coeds death tn any animal duying the Rericd © abgegvatlow V(LTsovthe Aime runsind Fe \all Se Cheat PoPuletiou ok test oaniirels a certain dote oh cored edracttou ae so). 233 2 E:G rsihiou ake Lwsocteh | Aust tert of Ake sled animals euPeced ecified Period of ee No Classification of insecttcides on the basis of Towerty On the basis of Aoi , ahe iseckttsda 3 have beer classified le the follows Yreut’s: (grou? 1- Prack non-Fertic comPourds having LDso oveh 1S,co0 mg/g like waled , AlyceUre, \ans line etc: GirouP 1 - Slightly Tonite comPourk having LOse rom Se00 te (5,50c0 mA§lley. 5 Metkexdehlor -Geee , Konattane — Bove , Pipeneny| - butexide -\\\Soc.- bes (qrcuP I1t- He doint Fonic comPouuds having Los. from c0 ta “Seoe m4 /ic§: Seven - Seo-loo » Malarthiou-iMoo, sulfur - 3009, _ Sabadola - (000 - ————————————————————— Assignment No Practical ts 2 Classificetion Of Insecticides P Based on chemical % ~ / ano cholatne & SS Assignment No Non oY as teO, sesh Perse ys ‘) Contact Poisons (Torougt ei) » Rese \njecticidas orn coPable of qaiawy ent ag © {ato tha insect body Wrevyy gdinpcks & wee Jrachag or through Abs cticle itself see OdT /Te Wjadk Poisons arelies dindlg on the, bods, of tasects tu the ferme oly string on dant Pantie! sof. gusneed ine Ane body wat £ coune 4a! 2) Stomach Poisons (Treugu mouth) “The insecdtades allied on Aha leares L thes Parts of Plants whew \nsects ingested Aug ako mouth £ rgach inte Ahn aqutve syslem “© Ae msecks which wollt ewe dootth: ok \ngeet- Eq- calcium arsenate, lend alse er ~~ =Gfomach Poisons should be Ralafable enough net *o agket Ake \nseets ~ (au +Re insects An lialy = Havin no PWytotomiaty — Stagad uniformly ove Kha Pla surface. 3) Fumigauts CTircvgn stinacles ; The ee Bade aR a off Poisonous Fumes Ard cabled Limigants — The ouicants ta ARE Zoam ok Reisonous vokours OL Fame eter Ito the Virals, the Qoisons fume sarert Aha Process oly Asstinatton f came doatr of insects - (use in any figuh envine nme fon atleast _\-3 dos) Ss E-4- Cyanide , carbou monoxide che. / Assignment No aos Prckerties obj an idoad insedicidas or ae be £ available in the manteed under dif be nal cuniisiis 2. Tk should be tonic £ (call the Gat rsahunsd to be contrciled 3- Tt sheutd vet be Phy totert te +2 croPs qo TA should not be Torte To now tegel

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