LEC3 P2

-Intial community:

a)colonization:

1-attachment by weak bond

2-then by strong bond ‘’dextran’’

b)growth:

1-formation of monolayer
2-verticle arrangement
3-then radiating from tooth surface

-Primary invaders are: pioneers

-Secondary invaders are: sterpt. Mutans

-Intermediate community:

1-sterpt mutans from ABUNDANT dextran, levan and

acids which attracts more microorganisms and cause the
positive and negative interaction effect which is:
a)Veillonela will flourish ‘’+ve interaction’’

b)pioneers will disappear ‘’-ve interaction’’

2-organization of microorganisms as:

a) the deepest layers has anaerobes
b) middle facultative anaerobes
c)outermost aerobes

-mature community = climax stage

- in mature community each filament is surrounded by
cocci ‘’ corn cobs appearance’’

-succession: change of habitats due to change of

environment
-autogenic: caused by the microorganism itself
-allogenic: caused by the host
-microbial succession is a dynamic process
-Resting pH: the pH of dental plaque after stoppage of
carbs intake from 8 to 12 hours
-critical pH: the pH of dental plaque under which
demineralization happens
-DMF index: which is used to differentiate between the
patients with high caries incidence and low ones
(decayed, missed, filled)
-in Stephane’s he did not the experiment only on
glucose he also did it on fructose…etc
-GR. Rapid fall of pH:
a)rabid diffuse of carbs in plaque
b)rabid action of microorganism on carbs to produce
acids
-GR. Slow return of pH:
a)diffusion limiting property (delay exist of acids and
delay entering of buffer)
b)breakdown of residual carbs absorbed even against
conc. Gradient
c)breakdown of intracellular polysaccharide
(amylopectin)
-enamel hypoplasia and hypocalcification affect the rate
of progression of caries but don’t initiate caries
-GR. Mongolism has less caries incidence
because they have high flow of saliva with its buffering
effect
-GR. Caries is a dynamic process
due to alternating periods of mineralization and
demineralization