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P re f a c e
A Com preh en s i ve V i ew of
N o n i n v a s i v e Ve n t i l a t i o n
Noninvasive ventilation (NIV), often referred to inter- states in which long-term NIV is used: obesity
changeably as noninvasive positive pressure venti- hypoventilation (Kaw and Kaminska), spinal cord
lation, is the focus of the current issue. One of the injury (Daoud and colleagues), Duchenne
earliest uses of the modern day NIV machines dates muscular dystrophy (MacKintosh and colleagues),
to the 1940s when a group from Columbia Univer- COPD (Orr and colleagues), amyotrophic lateral
sity at Bellevue Hospital devised an “automatic sclerosis (Cooksey and Sergew), Neuralgic Amyo-
respirator” to provide intermittent positive pressure trophy (Farr and colleagues), and common uses of
ventilation using a facemask for patients with acute NIV in the pediatric population (Shi and col-
respiratory failure.1 NIV was used during the polio leagues). Over time, various modes and settings
epidemic and was especially important for those have been developed to improve synchrony and
with disabilities and chronic respiratory failure to portability. These devices and modes are dis-
be able to live independently in community-based cussed (Singh and Cao) as well as the long-term
living centers.2 However, in the decades that fol- follow up of NIV (Choi and colleagues). The use
lowed, invasive ventilation become the mainstay of NIV in the perioperative period (Dupuy-McCau-
for the management of acute respiratory failure ley and Selim) and in the postacute phase, such as
while NIV fell out of favor. During the 1980s and in long-term rehabilitation centers (Brown), is also
1990s, NIV came back into focus as convincing ev- discussed. NIV can be titrated in a sleep lab for
idence was published to support the use of NIV for optimal results when feasible and if outpatient ti-
the hospital-based treatment of acute exacerba- trations fail. Given the versatile patient population
tions of chronic obstructive pulmonary disease with vastly differing requirements, a thoughtfully
(COPD) and acute pulmonary edema.3 NIV using designed and tailored sleep lab (Fiala and Cole-
a nasal mask (instead of a full facemask) was man) provides more optimal and personalized
first reported in 1987 by Ellis and colleagues4 in 5 results.
patients with neuromuscular weakness, which pro- Our collection of articles provides a comprehen-
vided more data and options for the use of long- sive review of the most pertinent issues in the use
term home NIV. and management of NIV. We chose well-regarded
Over the years, the indications for NIV have experts in each topic, and we are immensely
expanded to include various disease states. In proud and grateful for their contributions. We are
this issue, the authors discuss the key disease honored to have been a part of a series that will
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