DNA MILD-MODERATE HOSPITALIZED, HIGH FLOW

Alpha OUTPATIENT OXYGEN OR NIPPV

B.1.1.7 ARDS THERAPY
Bamvlanivimab + Estesevimab IL - 1 Dexamethasone
Beta LRTI symptoms
Casirivimab + Imdevimar
IL - 6
B.1.351 - COUGH IL - Tocilizumab
- DYSPNEA
Sotrovimar
Gamma Pulmonary Embolism Remdesivir Baricitinib
P.1 Delta is showing resistance
Delta Myocarditis HOSPITALIZED, NO Combo treatments HFNC (100% FIO2, 50-60 L/MIN)
BIPAP (100% FIO2, PEEP, PS)
B.1.617.2 Pericarditis OXYGEN THERAPY
R0 = 2-3 R0 = 5-9 Remdesevir + Dexamethasone
Epsilon Remdesivir Remdesevir + Baricitinib (if steroids CI)
B.1.427
B.1.429 URTI Symptoms (M/C) Only for high risk of HOSPITALIZED, MECHANICAL
progression VENTILATION/ECMO
- HEADACHE
- RUNNY NOSE Dexamethasone
- SORE THROAT
HOSPITALIZED, IL - 1
IL - 6 Tocilizumab (WITHIN 24HRS
Viral load: 1000x with delta vs. alpha - ANOSMIA OXYGEN THERAPY IL - OF ADMIT)
L/C
Transmissibility: 64% more transmissible - AGEUSIA Remdesivir (only)
Severity: 2 - 2.5x hospitalization rate IL - 1 for those with Ards net ventilation
TV: 6 - 8 CC/KG OF PBW
Prevalence: > 50 y/o & comorbidities Fever IL - 6 O2 requirements PLATEAU PRESSURE < 30CM H2O

< 50 y/o + unvaccinated IL - PEEP > 5CM H2O

Dexamethasone (only) E.C.M.O.
when combo isn’t possible
Hearing impairment
Remdesivir + Dexamethasone
PREVENTION
ACE - 2 RECEPTOR AFFINITY Nasal Cannula
1 - 6 L/MIN
Vaccination Risk of
FURIN CLEAVAGE Re-infection
VIRAL REPLICATION Tissue Nonrebreather moderate reduction in
if previously
efficacy against infection
ESCAPE FROM ANTIBODIES + T-CELLS? G.I. upset Gangrene (but better than unvaccinated) had covid
don’t i have
CYTOKINE
STORM ANTICOAGULATION high efficacy against natural
??? Long Covid Symptoms??? L.M.W.H.
hospitalization/death
(higher than unvaccinated)
immunity
against it?

Covid Symptoms > Weeks FONDAPARINUX NPI’s should be

re-instituted

The Delta Variant: Current Evidence and Literature -

COVID-19 | SARS-CoV-2 | Vaccine Efficacy