1.

)NCBI:NCBI is now a leading source for public biomedical databases, software

tools for analyzing molecular and genomic data, and research in computational
biology
2.)DDBJ:The DNA Data Bank of Japan is a biological database that collects DNA
sequences.
3.)UniProt:The Universal Protein Resource (UniProt) is a comprehensive resource for
protein sequence and annotation data.
4.)ChEMBL:ChEMBL is a manually curated database of bioactive molecules with drug-
like properties. It brings together chemical, bioactivity and genomic data to aid
the translation of genomic information into effective new drugs.
5.)Treefam:TreeFam (Tree families database) is a database of phylogenetic trees of
animal genes. It is a curated resource that aims to provide reliable information
about ortholog and paralog assignments, as well as an evolutionary history of
various gene families. TreeFam is also an ortholog database.
6.)BLAST:BLAST is an algorithm and program for comparing primary biological
sequence information, such as the amino-acid sequences of proteins or the
nucleotides of DNA and/or RNA sequences.
7.)CLUSTAL OMEGA:Clustal Omega is a multiple sequence alignment program for
aligning three or more sequences together in a computationally efficient and
accurate manner.
8.)PDB:The Protein Data Bank is a database for the three-dimensional structural
data of large biological molecules, such as proteins and nucleic acids.
9.)CATH:The CATH database provides hierarchical classification of protein domains
based on their folding patterns.
10.)SCOP:The Structural Classification of Proteins database is a largely manual
classification of protein structural domains based on similarities of their
structures and amino acid sequences.
11.)EXPASY:Expasy is an online bioinformatics resource operated by the SIB Swiss
Institute of Bioinformatics. It is an extensible and integrative portal which
provides access to over 160 databases and software tools and supports a range of
life science and clinical research areas, from genomics, proteomics and structural
biology, to evolution and phylogeny, systems biology and medical chemistry
12.)ERRAT:ERRAT is a program for verifying protein structures determined by
crystallography
13.)GALAXY:Galaxy is an open source, web-based platform for accessible,
reproducible, and transparent computational biomedical research. It allows users
without programming experience to easily specify parameters and run individual
tools as well as larger workflows
14.)PUBMED:PubMed is a free resource supporting the search and retrieval of
biomedical and life sciences literature with the aim of improving health–both
globally and personally, contains citations and abstracts of biomedical literature.
15.)KEGG:KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of
databases dealing with genomes, biological pathways, diseases, drugs, and chemical
substances. KEGG is utilized for bioinformatics research and education, including
data analysis in genomics, metagenomics, metabolomics and other omics studies,
modeling and simulation in systems biology, and translational research in drug
development.
16.)PROSITE:PROSITE is a protein database. It consists of entries describing the
protein families, domains and functional sites as well as amino acid patterns and
profiles in them.
17.)GENBANK:The GenBank sequence database is an open access, annotated collection
of all publicly available nucleotide sequences and their protein translations. It
is a comprehensive source of stable automatic annotation of individual genomes, and
of the synteny and orthology relationships between them.
18.)ENSEMBL:Ensembl is a bioinformatics project to organize biological information
around the sequences of large genomes.
19.)INTERPRO:InterPro is a database of protein families, domains and functional
sites in which identifiable features found in known proteins can be applied to new
protein sequences in order to functionally characterise them.
20.)STRING DATABASE:STRING is a database of known and predicted protein-protein
interactions.
21.)TrEMBL:TrEMBL is a computer-annotated protein sequence database supplementing
the SWISS-PROT Protein Sequence Data Bank.
22.)EMBOSS:EMBOSS is "The European Molecular Biology Open Software Suite". EMBOSS
is a free Open Source software analysis package specially developed for the needs
of the molecular biology
23.)MUSCLE:MUSCLE stands for MUltiple Sequence Comparison by Log- Expectation.
MUSCLE is claimed to achieve both better average accuracy and better speed than
ClustalW2 or T-Coffee
24.)JPRED:JPred is a Protein Secondary Structure Prediction server and has been in
operation since approximately 1998. JPred incorporates the Jnet algorithm in order
to make more accurate predictions.
25.)PIR:The Protein Information Resource (PIR) is an integrated public resource of
protein informatics that supports genomic and proteomic research and scientific
discovery.