Tulips:

RYZ EUVIAN FERRY

NIKAEL PATUN-OG
ZEDRIK YSAAK RAMENTO
BREN ALDRIN BIANZON

RHINITIS
AARON RHENZIE JOPIA

First contact with Subsequent contact

allergen with allergen

The allergen is taken up by The specific IgE antibodies on the surface

antigen-presenting cells, which of sensitized mast cells attach to an
then deliver it to immature T allergen, and when they cross-link, the
helper cells mast cell is activated

Mast cells release both already-existing and

Interleukins are produced by newly-formed mediators as a result of
the differentiation of T helper degranulation:
cells into TH2 cells
histamines
leukotrienes
prostaglandins

Interleukins and T2 cells

encourage B cells to produce IgE
antibodies against the allergen Early phase reactions: Late phase reactions:
sneeze blockage
itch hyperactivity
run hyposmia
Specific IgE antibodies bind to blockage
mast cell receptors, "sensitizing"
the mast cell to the allergen