This document discusses four conditions: Chronic Neutrophilic Leukemia (CNL), Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Leukemoid Reaction secondary to unknown infection. CNL, AML, and CML present with similar non-specific symptoms like malaise, weakness, and fever. The conditions can be distinguished based on factors like the patient's age and gender, specific abnormalities in blood cell counts and differentials, and presence or absence of certain cell types and features on microscopy.
This document discusses four conditions: Chronic Neutrophilic Leukemia (CNL), Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Leukemoid Reaction secondary to unknown infection. CNL, AML, and CML present with similar non-specific symptoms like malaise, weakness, and fever. The conditions can be distinguished based on factors like the patient's age and gender, specific abnormalities in blood cell counts and differentials, and presence or absence of certain cell types and features on microscopy.
This document discusses four conditions: Chronic Neutrophilic Leukemia (CNL), Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Leukemoid Reaction secondary to unknown infection. CNL, AML, and CML present with similar non-specific symptoms like malaise, weakness, and fever. The conditions can be distinguished based on factors like the patient's age and gender, specific abnormalities in blood cell counts and differentials, and presence or absence of certain cell types and features on microscopy.
Leukemia (CNL) Signs and Symptoms of Patient Malaise + + + + Weakness + + + + Fever - + + + Anorexia - + + + Weight Loss + + + + Risk Factors Age > 67 years old Increases with 65-75 years old Any age age Gender Both male and Male Male Both male and female female CBC Results Anemia Mild Anemia Normocytic, Normocytic, Normocytic, normochromic anemia normochromic normochromic anemia anemia WBC count Inc. High, normal, or Inc. Dec. (near normal) low Platelet Count Normal or slightly Dec. Inc. Dec. decreased Differential count Neutrophil bands w/ Hypo >80% + + + Segmentation Chronic mature neutrophilia Lymphocytes - Dec. - normal Eosinophils normal Eosinophilia eosinophilia normal Basophils Normal Normal Basophilia normal Neutrophils + - - + - Toxic granulation Monocytes - - - + - Large Vacuoles Erythrocyte Sedimentation elevated elevated elevated elevated Rate