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ALLERGY SCREEN**
ALLERGY PANELS*
Dust Panel
Food Panel
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Animal Panel
Mold Panel
Grass Panel
Weed Panel
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Note
· In vitro allergy tests are a valuable tool for the clinician to diagnose allergy, treat and predict disease
development.
· Allergy panels / Allergen specific IgE includes only common causative allergens and does not include all
possible allergens.
· In cases of food allergy, specific IgE antibodies may be undetectable inspite of a convincing clinical
history because these antibodies may be directed towards allergens that are revealed or altered during
industrial food processing, cooking or digestion and therefore do not exist in the original food for which
the patient is tested.
· Normal IgE levels do not necessarily exclude the possibility of allergy because certain allergies can be
non-IgE mediated.
· Very low levels of allergen specific IgE antibodies should be evaluated with caution when Total IgE
values exceed 100 kUA/L
· All results should be interpreted in relation to the individual case history.
Comments
Genetic factors in development of Allergic disease
------------------------------------------------------------
| Family history of allergic disease | Percentage risk |
|------------------------------------------|-----------------|
| No family member allergic | 5-15 |
|------------------------------------------|-----------------|
| One sibling allergic | 25-35 |
|------------------------------------------|-----------------|
| One parent allergic | 20-40 |
|------------------------------------------|-----------------|
| Both parents allergic | 40-60 |
|------------------------------------------|-----------------|
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Immunoglobulin E (IgE): The most important trigger molecule for allergic information. The level of IgE is low
during the first year of life, gradually increases with age and reaches adult levels after 10 years. As IgE is a
mediator of allergic response, quantitative measurement can provide useful information for differential
diagnosis of atopic and non-atopic disease. Patients with atopic diseases like Allergic asthma, Allergic rhinitis &
Atopic dermatitis have moderately levated IgE levels
Increased Levels - Atopic/Non-atopic allergy, Hyper IgE syndrome, Parasitic infections, IgE Myeloma,
Pulmonary Aspergillosis, Immunodeficiency states & Autoimmune diseases
Uses
· Evaluation of children with strong family history of allergies and early clinical signs of disease
· Evaluation of children and adults suspected of having allergic respiratory disease to establish the
diagnosis and define the allergens
· To confirm clinical expression of sensitivity to foods in patients with Anaphylactic sensitivity or
with Asthma, Angioedema or Cutaneous disease
· To evaluate sensitivity to insect venom allergens particularly as an aid in defining venom
specificity in those cases in which skin tests are equivocal
· To confirm the presence of IgE antibodies to certain occupational allergens
Allergy Panels: are reported as qualitative values for the broad identification of commonly associated
allergens
Allergen Specific IgE Interpretation
-----------------------------------------------------------
| QUANTITATIVE RESULT| LEVEL OF ALLERGEN | SYMPTOM RELATION |
| IN kUA/L | SPECIFIC ANTIBODY | |
|--------------------|-------------------|------------------|
| <0.10 | Undetectable | Unlikely |
|--------------------|-------------------|------------------|
| 0.10-0.50 | Very low | Uncommon |
|--------------------|-------------------|------------------|
| 0.50-2.00 | Low | Low |
|--------------------|-------------------|------------------|
| 2.00-15.00 | Moderate | Common |
|--------------------|-------------------|------------------|
| 15.00-50.00 | High | High |
|--------------------|-------------------|------------------|
| 50.00-100.00 | Very High | Very High |
|--------------------|-------------------|------------------|
| >100.00 | Very High | Very High |
-----------------------------------------------------------
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IMPORTANT INSTRUCTIONS
ŸTest results released pertain to the specimen submitted .ŸAll test results are dependent on the quality of the sample received by the Laboratory .
ŸLaboratory investigations are only a tool to facilitate in arriving at a diagnosis and should be clinically correlated by the Referring
Physician.ŸSample repeats are accepted on request of Referring Physician within 7 days post reporting.ŸReport delivery may be delayed due to
unforeseen circumstances. Inconvenience is regretted .ŸCertain tests may require further testing at additional cost for derivation of exact value .
Kindly submit request within 72 hours post reporting.ŸTest results may show interlaboratory variations .ŸThe Courts/Forum at Delhi shall have
exclusive jurisdiction in all disputes /claims concerning the test(s) & or results of test(s).ŸTest results are not valid for medico legal purposes .
ŸContact customer care Tel No. +91-11-39885050 for all queries related to test results.
(#) Sample drawn from outside source.
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