Aldehyde & Ketone : 8/

Reaction with N3H

Mechanism & Application

REACTION ON ALDEHYDE & KETONE

Substrate : Reagent :

Product :

Mechanism : pKa of N3H is 4.8

Summary :

Ph
O + N3 H
Me

O
+ N3H

Dr. Pallab Sarkar M.Sc , Ph.D

Aldehyde & Ketone : 8/

REACTION ON ACID DERIVATIVES

Schmidt Reaction

Substrate : Reagent :

Product :

Mechanism : Reaction intermediate :

Primary product :

Final product :

Summary :

Cartius Reaction

Substrate : Reagent :

Product :

Mechanism : Reaction intermediate :

Primary product :

Final product :

Summary :

Dr. Pallab Sarkar M.Sc , Ph.D

Aldehyde & Ketone : 8/

Hoffmann Bromamide Degredation Reaction

Substrate : Reagent :

Product :

Mechanism : Reaction intermediate :

Primary product :

Final product :

Summary :

Lossen Rearrangement

Substrate : Reagent :

Product :

Dr. Pallab Sarkar M.Sc , Ph.D

Aldehyde & Ketone : 8/

Mechanism :
Reaction intermediate :

Primary product :

Final product :

Summary :

Dr. Pallab Sarkar M.Sc , Ph.D