Activity 6: Protein

I. Answer each of the following for the amino acid shown:

A. name, three-letter, and one-letter abbreviations

Phenylalanine , Phe or F
B. polar or non polar
- Non polar
C. has a neutral, acidic, or basic R group
- basic R group

Interaction with water as hydrophobic or hydrophilic

A. name, three-letter, and one-letter abbreviations
Serine, Ser, S
B. Polar or Non polar
- polar
C.hasaNeutral, acidic, or basic R group
- basic R group
Interaction with water as hydrophobic or hydrophilic
- Hydrophilic

II.Draw on paper (and attach here), using Fischer projections, each amino acid as it would
appear at pH 7.

II.
III. Draw on paper (and attach here) the structural form of the amino acid
alanine that predominates in solution at each of the following pH values.

IV. Draw the structures of the following proteins using PepDraw and attach your work here.

A. GLYCINE, PHENYLALANINE, AND THREONINE

B. LYSINE, ALANINE, AND ISOLEUCINE

 C. TYROSINE, SERINE, AND METHIONINE

D. VALINE, THREONINE, PROLINE, HISTIDINE

VI. Identify the amino acid backbone in the polypeptide whose structure is shown here by placing a
circle around each amino acid and write the primary structure of this polypeptide.

1.
2.

3.Glucopyranose (B-D-Glucose)

4.
 V. Give the IUPAC name of the following proteins.

A.

B. Alanyl-α-glutamylglycyllysine
C.

D.
 VI. Explain why each of the following pairs are complementary proteins:

a. corn and peas

- Corn and peas are both high in protein. Corn lacks the amino acids tryptophan and
lysine, which are found in peas. Peas, on the other hand, lack methionine, which
corn offers. As a result, corn and peas form a complementary protein source.

b. rice and soy

- A complete protein is created by combining beans (soy) and grains (rice). Both soy
and rice are deficient in certain critical amino acids. However, when eaten together,
each adds what the other lacks to produce a complete protein.
c. almonds and peanuts
- Peanuts supply the necessary amino acid lysine, which almonds do not. Almonds
contain the necessary amino acids methionine and cysteine, which peanuts do not.
As a result, almonds and peanuts provide a complementary protein source.

VII. Proteins perform so many important roles for many organisms. In higher organisms like
humans, one of the many important roles of proteins is the delivery of oxygen throughout the
body. List two important transport proteins and describe their significance in the body.

Channel Protein

These proteins are distinguished by their ability to access both the intracellular and extracellular
spaces at the same time. Typically, channels or pores are engineered to allow only one type of substance
to pass through.The passage of polar and charged chemicals through a channel protein helps them to
circumvent the hydrophobic core of the plasma membrane, which would otherwise impede or prohibit
their entry into the cell. A channel protein generates a tunnel that allows a specific chemical to penetrate
the membrane (down its concentration gradient). Carrier proteins are transport proteins that are only
open to one side of the membrane at once.Membrane carrier proteins are crucial transmembrane
polypeptide molecules that allow charged and polar molecules and ions to flow through cell membrane
lipid bilayers.

Submitted by:
Aradillos Ma.Belinda
Brinquis Cesyl