You are on page 1of 7

CLINICAL RESEARCH

Implant survival and biologic complications of implant fixed


complete dental prostheses: An up to 5-year retrospective
study
Konstantinos Chochlidakis, DDS, MS,a Carlo Ercoli, DDS, MBA,b Erna Einarsdottir, DDS, MS,c
Davide Romeo, DDS, PhD,d Panos Papaspyridakos, DDS, MS, PhD,e Abdul Basir Barmak, MD, MSc, EdD,f and
Alexandra Tsigarida, DDS, MSg

Implant-supported fixed pros- ABSTRACT


theses have been a successful Statement of problem. Limited information is available on the association between prosthesis-
treatment for completely associated risk factors and biologic complications for patients with implant fixed complete dental
edentulous patients1-3 and prostheses (IFCDPs).
have been used in conjunction
Purpose. The purpose of this retrospective study was to assess the implant survival and biologic
with delayed or immediate complications of IFCDPs up to 5 years of follow-up.
loading protocols.4,5 Longitu-
dinal studies and systematic Material and methods. Patients who had received IFCDPs between August 1, 2009 and August 1,
2014 were identified through an electronic health record review. Those who consented to
reviews have reported high
participate in the study attended a single-visit study appointment. Clinical and radiographic
implant survival rates for examinations, intraoral photographs, and peri-implant hard and soft tissues parameters were
IFCDPs.5,6 Predictably, though, assessed. Only prostheses which could be removed during the study visit were included.
with the increased adoption of Associations between biologic complications and prosthetic factors, such as time with prosthesis
these prostheses by dentists in place, prosthesis material, number of implants, cantilever length, and type of prosthesis
and their use in a variety of retention, were assessed.
clinical situations, complica- Results. A total of 37 participants (mean ±standard deviation age 62.35 ±10.39 years) with 43
tions have also arisen.5,6 While IFCDPs were included. None of the implants had failed, leading to an implant survival of 100%
complications can be broadly at 5.1 ±2.21 years. Ten of the prostheses were metal-ceramic (Group MC) and 33 were metal-
divided into mechanical and acrylic resin (Group MR). Minor complications were more frequent than major ones. Considering
biologic,3,6-10 the available evi- minor complications, peri-implant mucositis was found in 53% of the implant sites, more often
in the maxilla (P=.001). The most common major biologic complication was peri-implantitis,
dence on the associations be- which affected 4.0% of the implants, more often in the mandible (P=.025). Peri-implant soft
tween prosthesis-related tissue hypertrophy was present 2.79 times more often (95% CI: 1.35 e 5.76, P<.003) around
factors and biologic complica- implants supporting metal-acrylic resin prostheses than metal-ceramic ones, with the former
tions is somewhat type also showing significantly more plaque accumulation (P<.003).
scarce.2,5-7,11-17 Conclusions. Biologic complications such as soft tissue hypertrophy and plaque accumulation were
According to the consensus more often associated with metal-acrylic resin prostheses. Peri-implant mucositis occurred more
report of the 2017 World often under maxillary IFCDPs, while peri-implantitis appeared more common around mandibular
Workshop on the classification implants. (J Prosthet Dent 2021;-:---)

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
a
Associate Professor, Program Director, Department of Prosthodontics, Eastman Institute for Oral Health, University of Rochester, Rochester, NY.
b
Professor, Prosthodontics and Periodontics, Chair, Department of Prosthodontics, Eastman Institute for Oral Health, University of Rochester, Rochester, NY.
c
Assistant Professor, University of Iceland, Reykjavik, Iceland.
d
Resident, Department of Prosthodontics, Eastman Institute for Oral Health, University of Rochester, Rochester, NY; and Adjunct Assistant Professor, Advanced Oral Surgery
Unit, Vita Salute University, San Raffaele Hospital, Milan, Italy.
e
Associate Professor, Department of Prosthodontics, Tufts School of Dental Medicine, Boston, Mass; and Visiting Associate Professor, Eastman Institute for Oral Health,
University of Rochester, Rochester, NY.
f
Assistant Professor, Eastman Institute for Oral Health, University of Rochester, Rochester, NY.
g
Associate Professor, Program Director, Department of Periodontics, Eastman Institute for Oral Health, University of Rochester, Rochester, NY.

THE JOURNAL OF PROSTHETIC DENTISTRY 1


2 Volume - Issue -

Table 1. Inclusion and exclusion criteria


Clinical Implications Inclusion Criteria Exclusion Criteria
Patients treated at the Eastman Patients treated at different dental
Even though high implant survival rates have been Institute for Oral Health practice locations
reported with IFCDPs, biologic complications are Age 18 years at the day of Age < 18 years old at the day of
implant placement implant placement
unfortunately quite frequent. Clinicians and patients
Dental implants with rough Smooth (machined) surface dental
should be aware of the increased prevalence of surface implants
maxillary arch peri-implant mucositis, soft tissue Completely edentulous patients Completely dentate or partially
hypertrophy, and plaque accumulation under with IFCDPs in at least one jaw edentulous patients
metal-acrylic resin prostheses and design the Definitive prosthesis under Definitive prosthesis under functional
functional loading for at least loading for less than 1 year
intaglio surface to allow adequate access for plaque 1 year
removal measures, especially for metal-acrylic resin
IFCDPs.

hypothesis was that biologic complications would not be


associated with the selected prosthetic risk factors.
of periodontal and peri-implant diseases and conditions,
healthy peri-implant tissues are characterized by the
MATERIAL AND METHODS
absence of erythema, bleeding on probing, swelling, and
suppuration.18 Peri-implant mucositis is then considered The protocol for patients receiving treatment at the
present when peri-implant soft tissues bleed on gentle Eastman Institute for Oral Health (EIOH), University of
probing while erythema, swelling, and/or suppuration Rochester, has included motivation and instruction on
may also be present.18 Peri-implantitis is instead defined the importance of self-performed plaque removal from
as the presence of bleeding and/or suppuration on gentle their initial visit, throughout their treatment, and at the
probing, probing depths of 6 mm, and bone levels 3 time of prosthesis delivery. They are encouraged to enroll
mm apical to the most coronal portion of the intra- in an annual maintenance program, where the IFCDP is
osseous part of the implant.18 removed and ultrasonically cleaned and stains removed,
A 4-year retrospective study on 378 implants sup- after which a dental hygienist removes plaque and cal-
porting 72 IFCDPs reported a prevalence of 56.9% for culus from the implants and/or the abutments. Oral
peri-implant mucositis and 14.3% for peri-implantitis.19 hygiene motivation is reinforced at these periodic
In another study, biologic complications affecting the maintenance appointments.
implants were, in decreasing order of prevalence, soft The University of Rochester Research Subject Review
tissue recession (7.7% annual rate), inflammation (7.4% Board (RSRB) committee approved the protocol for this
annual rate), peri-implant mucositis (6.3% annual rate), retrospective study (RSRB #58008). The electronic health
and peri-implantitis (2.0% annual rate).20 records (EHR) of all patients who had received an IFCDP
Since peri-implant mucositis and peri-implantitis are between August 1, 2009 and August 1, 2014 at EIOH
defined as biofilm-mediated diseases,18 it is important to were reviewed according to the inclusion and exclusion
provide the patient with adequate access for plaque criteria (Table 1). Patients were informed about the ob-
removal. Therefore, prosthetic-related factors such as jectives of the study, and those who agreed to participate
cantilever length, type of prosthesis material, prosthesis signed a written informed consent form in accordance
dimensions, and design of the intaglio surface may affect with the Declaration of Helsinki.
plaque accumulation and the ability of the patient to The study participants attended a single research visit
carry out plaque removal and may indirectly influence the appointment in which a comprehensive examination of
prevalence of biologic complications around implants the soft and hard tissue was completed by 2 calibrated
supporting IFCDPs.20-27 In addition, from a diagnostic examiners (E.E., K.C.). The examination consisted of
standpoint, the identification of peri-implant mucositis dental and medical history review, intraoral photographs,
and peri-implantitis requires unimpeded access to the and radiographic and clinical examination. During this
implant site, especially for peri-implant probing; often, visit, information was recorded for both prosthetic and
this may not be achievable, especially for bulky pros- biologic complications. The prosthetic findings have been
theses, unless the prosthesis is removed. previously reported.21
The primary aim of this retrospective study was to Peri-implant parameters were assessed by 2 calibrated
assess implant survival and the prevalence of biologic clinicians (A.T., E.E.). These consisted of the presence or
complications for participants treated with IFCDPs after absence of peri-implant suppuration and/or fistula;
an up to 5-year observation period. The secondary aim of modified plaque index (mPLI) and modified sulcus
this study was to identify prosthesis-related factors bleeding index (mSBI) at 6 peri-implant sites (dis-
associated with biologic complications. The null tobuccal, buccal, mesiobuccal, distolingual, lingual, and

THE JOURNAL OF PROSTHETIC DENTISTRY Chochlidakis et al


- 2021 3

Table 2. Prosthesis-related factors Table 3. Descriptive overview of participants, location, and material of
Prosthesis Related Factors IFCDPs
Factor Type Characteristics Number
IFCDP material Metal-resin/metal-ceramic Participants 37
IFCDP retention Screw-retained/cement-retained Female/male 24/13
IFCDP location Maxilla/mandible Maxilla/mandible 23/20
Cantilever extension Yes/no, left/right Metal-resin/metal-ceramic 33/10
Time with IFCDP in place Months Screw-retained (SR)/cement-retained (CR) 37/6
Presence of bruxism Yes/no Implant level/abutment level 12/31
Nightguard use Yes/no Number of implants 244
Implant connection Internal/external Implants axial/implants distally tilted 231/13
Implant location Anterior/posterior Implants SR IFCDPs/implants CR IFCDP 207/37
Immediately loaded implants/conventionally loaded implants 72/172
Anterior implants/posterior implants 120/124
Mean time with implants in place 5.1 years
mesiolingual); and the probing depths (PDs) (Probe UNC
Mean time with prostheses in place 3.7 years
15; Hu Friedy) recorded to the nearest millimeter at the
same 6 sites around the implant.27,28 In order to perform
accurate measurements of the peri-implant parameters,
These were assessed in the present study, providing data
especially PDs, only IFCDPs which could be removed
for 244 implant sites. Descriptive statistics are reported in
were included in the analysis.
Table 3.
The radiographic examination included periapical ra-
The total number of biologic complications was 324
diographs of each implant and the assessment of the
(311 minor and 13 major) and, at the prosthesis level, all
proximal crestal bone levels. Crestal bone levels were
had complications. At the implant level, however, 58 of
compared with the radiographs made at the delivery
244 implants were free of complications (Table 4).
appointment of the definitive prosthesis. The use of a
Descriptive statistics for minor complications are pre-
standardized radiographic device was not possible
sented in Table 5. Only 13 of 43 IFCDPs (30.2%) were
because of the retrospective nature of the study. A
free of soft tissue inflammation. The most common mi-
diagnosis of peri-implantitis was made when the clinical
nor complication was peri-implant mucositis, observed in
and radiographic examination showed hard and soft
172 of 244 implants (70.5%), followed by peri-implant
tissue findings that were consistent with current diag-
hypertrophy in 109 of 244 implants (44.7%).
nostic criteria.18
Of the selected participant- and prosthesis-related
Biologic complications were divided into minor and
factors, only jaw location was a significant predictor for
major.20 Minor complications included inflammation
the counts of peri-implant mucositis (Beta=0.560, stan-
under the prosthesis, peri-implant mucositis, and hy-
dard error [SE] =0.163, P=.001). The rate ratio for peri-
pertrophy or hyperplasia of the soft tissue, while peri-
implant mucositis sites for the maxilla was 1.75 (95%
implantitis and implant failures were considered major
confidence interval [CI]: 1.27e2.14) times as compared
complications.20
with the mandible (114 maxillary versus 58 mandibular
Descriptive statistics (counts and percentages) were
implants). In addition, material type and time from implant
used to report the biologic complication rates. The
in place were found to be significant predictors for the
Poisson regression analysis was used to evaluate the ef-
counts of peri-implant hypertrophy (Beta=1.028,
fect of selected prosthesis-related factors (Table 2) on the
SE =0.370, P=.006). The rate ratio of implant for peri-
number of minor and major biologic complications. All
implant hypertrophy in MR IFCDPs was 2.79 (95% CI:
computations were carried out with a statistical software
1.35 e 5.76) times as compared with MC IFCDPs (Table 6).
program (IBM SPSS Statistics, v25; IBM Corp) (a=.05).
Descriptive statistics for major complications are pre-
sented in Table 5. None of the 244 implants were lost
RESULTS
during the observation period, leading to 100% implant
A total of 37 individuals (mean ±standard deviation age survival rate at 5.1 ±2.21 years. However, 13 major com-
62.35 ±10.39 years) agreed to participate. Twenty-four plications were recorded. All these were peri-implantitis
women (mean ±standard deviation age 64.54 ±8.57 events and were observed in 5 anterior and 8 posterior
years) and 13 men (mean ±standard deviation age 58.3 implants in 6 IFCDPs. Jaw location was found to be the
±12.47 years) received a total of 271 moderately rough- only significant predictor for the counts of peri-implantitis
surface dental implants and 48 prostheses (24 maxillary (Beta=-1.75, SE =0.785, P=.025) as the rate ratio for peri-
and 24 mandibular).21 Of the 48 prostheses, only 43 implantitis sites for mandibular implants was 5.79 (95%
could be removed during the research visit, enabling CI: 1.24 e 27.02) times compared with that of maxillary
direct measurements for the peri-implant parameter. implants (2 maxillary versus 11 mandibular implants).

Chochlidakis et al THE JOURNAL OF PROSTHETIC DENTISTRY


4 Volume - Issue -

Table 4. Summary of minor, major, and total complications


No. of Prostheses No. of Prostheses Total No. of Complications Mean No. of Complications Mean No. of Complications
Complications with Complications Free of Complications (% of Total) per Affected Prostheses per Total Prostheses
Minor complications 43 0 311 (95.99) 7.23 (311/43) 7.23 (311/43)
Major complications 6 37 13 (4.01) 2.17 (13/6) 0.30 (13/43)

Table 5. Details of minor and major biological complications


Complication Total No. of Prostheses, Implants No. of Prostheses with Complications No. of Complications Complication (%)
Minor complications 43 prostheses 43 311 96.0
Peri-implant mucositis 244 implants 40 172 53.1
Hypertrophy/hyperplasia of soft tissue 244 implants 26 109 33.6
Inflammation under the prosthesis 43 prostheses 30 30 9.3
Major complications 43 prostheses 6 13 4.0
Peri-implantitis 244 implants 6 13 4.0
Implant failure 244 implants 0 0 0
Total 43 prostheses 43 324 100

Table 6. Overview of biological complications; comparison between groups


Group Metal-Resin (MR)
Complication Total No of Prostheses, Implants No. of Prostheses with Complications No. of Complications Complication (%)
Minor complications 33 prostheses 33 254 95.5
Peri-implant mucositis 182 implants 33 135 50.7
Hypertrophy/hyperplasia of soft tissue 182 implants 23 96 36.1
Inflammation under the prosthesis 33 prostheses 23 23 8.6
Major complications 33 prostheses 5 12 4.5
Peri-implantitis 182 implants 5 12 4.5
Implant failure 182 implants 0 0 0
TOTAL 33 prostheses 33 266 100

Group Metal-Ceramic (MC)


Complication Total No of Prostheses, Implants No. of prostheses with complications No. of complications Complication (%)
Minor complications 10 prostheses 10 57 98.3
Peri-implant mucositis 62 implants 10 37 63.8
Hypertrophy/hyperplasia of soft tissue 62 implants 3 13 22.4
Inflammation under the prosthesis 10 prostheses 7 7 12.1
Major complications 10 prostheses 1 1 1.7
Peri-implantitis 62 implants 1 1 1.7
Implant failure 62 implants 0 0 0
Total 10 prostheses 10 58 100

Descriptive statistics for peri-implant parameters are prosthetic risk factors. Although no implants were lost,
presented in Table 7. No statistically significant associa- the survival rate was 100%, similar to that of other
tion between any of the 3 peri-implant indices (PD, BoP, studies.11-17 However, biologic complications were
and mPLI) except for mPLI, which was associated with common, with no prosthesis being complication-free.
MR ISFCDs (P<.003). MR IFCDPs showed significantly A finding that was similar to previously reported
more plaque accumulation than MC IFCDPs in dis- data2,11,15-17,20 and underscores that emphasis should
tobuccal sites (P=.003), as well as buccal sites (P=.005). be placed not only on implant survival but also on the
overall prevalence of complications. Of the minor com-
plications, peri-implant mucositis was prevalent and
DISCUSSION
more often found than previously reported in a system-
The null hypothesis of this retrospective study was atic review.22 This increased prevalence of peri-implant
rejected, as peri-implant mucositis, peri-implant hyper- mucositis could be partially explained by the methodol-
trophy, and peri-implantitis were associated with ogy used in this study, as all IFCDPs were removed

THE JOURNAL OF PROSTHETIC DENTISTRY Chochlidakis et al


- 2021 5

before peri-implant measurements were recorded, unlike Table 7. Details of implants with probing depth higher than 5 mm and
in previous studies.11,15-17,20,22 Removing the prostheses positive evidence for plaque accumulation (mPLI) and bleeding on
was done to ensure that access to the implant site was probing (BoP)
Maxilla Mandible
not impeded by the prosthesis, potentially skewing the
Anterior/ Posterior/ Anterior/ Posterior/
peri-implant measurements. The authors are unaware of Peri-implant Indices Total (%) Total (%) Total (%) Total (%)
a previous study that evaluated peri-implant indices PD>5 mm 11/120 (9.2) 4/124 (3.2) 2/120 (1.7) 5/124 (4.0)
directly at 6 sites around each implant after the removal mPLI positive 40/120 (33.3) 57/124 (46.0) 38/120 (31.7) 34/124 (27.4)
of the IFCDPs. BoP positive 51/120 (42.5) 61/124 (49.2) 33/120 (27.5) 28/124 (22.6)
Strong evidence from animal and human experi-
mental studies indicates that plaque is the etiological
factor for peri-implant mucositis.7,20,22,23 In the present
study, peri-implant mucositis was more often found with the latter showing significantly more plaque accu-
under the maxillary prosthesis, consistent with a micro- mulation (P<.003). In addition, peri-implant hypertrophy
biological and immunological study on patients with was 2.79 (95% CI: 1.35 e 5.76) and more often present for
complete-arch fixed implant prostheses.29 In maxillary MR IFCDPs, presumably because of the generally larger
arches, the prosthesis may be designed with tissue con- dimensions of MR prostheses, which may have partially
tact to avoid or minimize phonetic problems, to hide the hindered effective self-performed plaque removal. This
prosthesis-tissue junction, and to avoid saliva visibly finding is consistent with the findings of previous articles
protruding in the peri-implant areas. While it is impor- showing that inability to perform plaque removal was
tant to design the intaglio surface of the maxillary pros- associated with biologic complications.36 In addition,
thesis to minimize these relevant patient concerns, the acrylic resin materials degrade and have increased plaque
design should not hinder plaque removal by the patient. accumulation.20
An appropriate design should have prosthesis contact Peri-implantitis is a biofilm mediated process which is
with the soft tissue similar to that of a modified ridge lap characterized by tissue inflammation and bone loss. In
pontic design, specifically by designing prosthesis contact the present study, the prevalence of peri-implantitis was
with the soft tissue toward the buccal aspect of the 5.80% (13/224) at the implant level, which is lower than
prosthesis yet maintaining a flat or convex intaglio design previously reported.20,22,23,37 A meta-analysis of previous
toward the palatal side that allows unimpeded plaque studies reported that the mean prevalence of 5-year
removal measures.20,30-32 In the present study, the implant-level peri-implantitis was 9.25%.22 This meta-
prosthetic design was not always consistent with these analysis showed that peri-implant diseases were preva-
guidelines, because different residents and dental labo- lent and the prevalence of peri-implantitis increased over
ratory technicians were involved in the fabrication of the time.22 In the present study, jaw location was found as
IFCDPs. It is therefore likely that less than ideal pros- the only significant predictor for the counts of peri-
thesis design led to an increased prevalence of peri- implantitis (Beta=-1.75, SE =0.785, P=.025). The rate
implant mucositis. In addition, periodic maintenance ratio for peri-implantitis in the mandible was 5.79 (95%
and supportive periodontal therapy is important to CI: 1.24 e 27.02) times that of the maxilla (95% CI: 0.03 e
minimize biofilm-mediated complications.30-35 While 0.80) (11 mandibular versus 2 maxillary implants). This
regular hygiene and recall protocols were in place, finding was consistent with the findings of previous
compliance with maintenance appointments and self- studies reporting that the prevalence of peri-implantitis
performed plaque removal in this study cohort was less was greater for mandibular implants and for
than ideal. Indeed, few patients attended their mainte- IFCDPs38,39 but not with those of other studies where the
nance visits as scheduled. This relative lack of compliance prevalence of peri-implantitis was greater in the maxillary
likely exposed the study cohort to an increased preva- arches.40,41 A possible explanation for the greater prev-
lence of biologic complications such as peri-implant alence of peri-implantitis in the mandible, is related to
mucositis. While this lack of compliance can affect and the potentially smaller width of the keratinized mucosa
skew the results for biologic complications, the authors present in mandibular edentulous arches.18 While the
believe that the overall results are descriptive of the evidence for the importance of peri-implant keratinized
effectiveness rather than the efficacy of the reported mucosa for peri-implant health is equivocal,18 an
prosthetic intervention, because this patient cohort was adequate band of keratinized mucosa has been reported
treated under real world conditions rather than in strict to facilitate comfortable, self-performed measures of
and ideal controlled conditions related to self-performed plaque removal, thereby decreasing the presence of a
plaque removal and compliance with periodic biofilm.42-44 However, in the present study, the width of
maintenance. peri-implant mucosa was not assessed, so a definitive
The plaque accumulation (mPLI) index values were conclusion about the greater prevalence of peri-
significantly different between MC and MR prostheses, implantitis for mandibular implants cannot be drawn.

Chochlidakis et al THE JOURNAL OF PROSTHETIC DENTISTRY


6 Volume - Issue -

Analysis of the peri-implant indices (PD, BoP, mPLI) while the most common major biologic complica-
and crestal bone remodeling showed no significant dif- tion was peri-implantitis (4.0% complication rate).
ference between either axially or distally tilted implants 4. Maxillary implants were more often surrounded by
or anterior and posterior implants.45,46 This is consistent tissues affected by hypertrophy and peri-implant
with a systematic review that reported no differences in mucositis, while peri-implantitis was more often
clinical performance between implants that were placed found associated with mandibular implants.
in an axial position relative to the residual alveolar ridge 5. Metal-acrylic resin prostheses were more often
when compared with implants that were intentionally associated with tissue hypertrophy and plaque
tilted toward the distal aspect of edentulous jaws.45,47 accumulation than metal-ceramic prostheses.
That all IFCDPs were removed before the soft tissues
parameters were assessed and recorded was a strength of REFERENCES
the present study. While mean peri-implant indices and 1. Douglass CW, Shih A, Ostry L. Will there be a need for complete dentures in
measurements such as probing depths and bleeding on the United States in 2020? J Prosthet Dent 2002;87:5-8.
2. Papaspyridakos P, Bordin TB, Kim YJ, El-Rafie K, Pagni SE, Natto ZS, et al.
probing may not necessarily correlate with mean bone Technical complications and prosthesis survival rates with implant-supported
loss,48,49 assessing them correctly at the implant level in fixed complete dental prostheses: A retrospective study with 1- to 12-year
follow-up. J Prosthodont 2020;29:3-11.
such a way that adequate diagnosis can be formulated for 3. Zarb GA, Schmitt A. The edentulous predicament. I: A prospective study of
each implant is important.18 While patients with IFCDPs the effectiveness of implant-supported fixed prostheses. J Am Dent Assoc
1996;127:59-65.
should be enrolled in a maintenance protocol and peri- 4. Esposito M, Grusovin MG, Maghaireh H, Worthington HV. Interventions for
odically attend dental appointments, the ability to replacing missing teeth: different times for loading dental implants. Cochrane
Database Syst Rev 2013;3:1-96.
perform a comprehensive evaluation correctly, including 5. Papaspyridakos P, Mokti M, Chen CJ, Benic GI, Gallucci GO,
the assessment of soft tissue parameters (probing depths, Chronopoulos V. Implant and prosthodontic survival rates with implant fixed
complete dental prostheses in the edentulous mandible after at least 5 years:
bleeding, suppuration, swelling), can be affected by the a systematic review. Clin Implant Dent Relat Res 2014;16:705-17.
dimensions and retrievability of the prostheses. The 6. Pjetursson BE, Asgeirsson AG, Zwahlen M, Sailer I. Improvements in
implant dentistry over the last decade: Comparison of survival and compli-
presence of a nonremovable prosthesis, especially if cation rates in older and newer publications. Int J Oral Maxillofac Implants
relatively bulky, may significantly hinder the clinical 2014;29(Suppl):308-24.
7. Heitz-Mayfield LJ, Needleman I, Salvi GE, Pjetursson BE. Consensus state-
assessment of the peri-implant soft tissues during ments and clinical recommendations for prevention and management of
maintenance appointments. Additional protocols aimed biologic and technical implant complications. Int J Oral Maxillofac Implants
2014;29(Suppl):346-50.
at reducing plaque accumulation, including antiseptic 8. Papaspyridakos P, Chen CJ, Chuang SK, Weber HP, Gallucci GO.
mouth rinses, use of ultrasonic devices, short interval A systematic review of biologic and technical complications with fixed
implant rehabilitations for edentulous patients. Int J Oral Maxillofac Implants
follow-up appointments as previously described in the 2012;27:102-10.
literature may also reduce the prevalence of biologic 9. Zarb GA, Schmitt A. The longitudinal clinical effectiveness of osseointegrated
complications.18,50 dental implants: the Toronto study. Part III: Problems and complications
encountered. J Prosthet Dent 1990;64:185-94.
Limitations of the present retrospective study may 10. Zarb GA, Schmitt A. The longitudinal clinical effectiveness of osseointegrated
dental implants: the Toronto Study. Part II: The prosthetic results. J Prosthet
include inaccurate reporting from the residents’ chart Dent 1990;64:53-61.
notes throughout the observational period as well as no 11. Papaspyridakos P, Bordin TB, Natto ZS, El-Rafie K, Pagni SE,
Chochlidakis K, et al. Complications and survival rates of 55 metal-ceramic
standardized and strict maintenance protocol for all the implant-supported fixed complete-arch prostheses: A cohort study with
included participants. Another limitation was that only mean 5-year follow-up. J Prosthet Dent 2019;122:441-9.
12. Jemt T, Nilsson M, Olsson M, Stenport VF. Associations between early
37 out of the 88 potential eligible patients contacted implant failure, patient age, and patient mortality: A 15-year follow-up study
agreed to participate in the study. The patients who did on 2,566 patients treated with implant-supported prostheses in the eden-
tulous jaw. Int J Prosthodont 2017;30:189-97.
not agree to participate in the study may have possibly 13. Jemt T. Implant survival in the edentulous jaw: 30 years of experience.
experienced fewer biologic complications than those who Part I: A retro-prospective multivariate regression analysis of overall
implant failure in 4,585 consecutively treated arches. Int J Prosthodont
participated in the study. 2018;31:425-35.
14. Jemt T. Implant survival in the edentulous jaw: 30 years of experience. Part II:
A retro-prospective multivariate regression analysis related to treated arch
CONCLUSIONS and implant surface roughness. Int J Prosthodont 2018;31:531-9.
15. Maló P, de Araújo Nobre M, Lopes A, Ferro A, Botto J. The all-on-4 treat-
Based on the findings of this retrospective study, the ment concept for the rehabilitation of the completely edentulous mandible: A
following conclusions were drawn: longitudinal study with 10 to 18 years of follow-up. Clin Implant Dent
Related Res 2019;21:565-77.
16. Maló P, de Araújo Nobre M, Lopes A, Ferro A, Nunes M. The all-on-4
1. IFCDPs presented with 100% implant survival rates concept for full-arch rehabilitation of the edentulous maxillae: A longitudinal
at 5.1 ±2.21 years, irrespective of the type of pros- study with 5-13 years of follow-up. Clin Implant Dent Related Res 2019;21:
538-49.
thesis material. 17. Papaspyridakos P, Bordin TB, Natto ZS, Kim YJ, El-Rafie K, Tsigarida A, et al.
2. The prevalence of complications, especially minor Double full-arch fixed implant-supported prostheses: Outcomes and com-
plications after a mean follow-up of 5 years. J Prosthodont 2019;28:387-97.
ones, was common and affected all prostheses and a 18. Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM,
large portion of the supporting implants. et al. Peri-implant diseases and conditions: Consensus report of workgroup 4
of the 2017 World Workshop on the Classification of Periodontal and Peri-
3. The most common minor biologic complication was Implant Diseases and Conditions. J Clin Periodontol 2018;45(Suppl 20):
peri-implant mucositis (53.1% complication rate), S286-91.

THE JOURNAL OF PROSTHETIC DENTISTRY Chochlidakis et al


- 2021 7

19. Cercadillo-Ibarguren I, Sánchez-Torres A, Figueiredo R, Schwarz F, Gay- prostheses who are receiving long-term nursing care. Gerodontology
Escoda C, Valmaseda-Castellón E. Immediately loaded implant-supported 2009;26:245-9.
full-arches: Peri-implant status after 1-9 years in a private practice. J Dent 36. Serino G, Strom C. Peri-implantitis in partially edentulous patients:
2017;67:72-6. association with inadequate plaque control. Clin Oral Implants Res 2009;20:
20. Papaspyridakos P, Barizan Bordin T, Kim YJ, DeFuria C, Pagni SE, 169-74.
Chochlidakis K, et al. Implant survival rates and biologic complications with 37. Papaspyridakos P, Chen CJ, Singh M, Weber HP, Gallucci GO. Success
implant-supported fixed complete dental prostheses: A retrospective study criteria in implant dentistry: A systematic review. J Dent Res 2012;91:242-8.
with up to 12-year follow-up. Clin Oral Implants Res 2018;29:881-93. 38. Dalago HR, Schuldt Filho G, Rodrigues MA, Renvert S, Bianchini MA. Risk
21. Chochlidakis K, Einarsdottir E, Tsigarida A, Papaspyridakos P, Romeo D, indicators for Peri-implantitis. A cross-sectional study with 916 implants. Clin
Barmak AB, et al. Survival rates and prosthetic complications of implant fixed Oral Implants Res 2017;28:144-50.
complete dental prostheses: An up to 5-year retrospective study. J Prosthet 39. Cavalli N, Corbella S, Taschieri S, Francetti L. Prevalence of peri-implant
Dent 2020;124:539-46. mucositis and peri-implantitis in patients treated with a combination of axial
22. Lee CT, Huang YW, Zhu L, Weltman R. Prevalences of peri-implantitis and and tilted implants supporting a complete fixed denture. Scientific World
peri-implant mucositis: systematic review and meta-analysis. J Dent 2017;62: Journal 2015;2015:1-8.
1-12. 40. Koldsland OC, Scheie AA, Aass AM. The association between selected risk
23. Francetti L, Cavalli N, Taschieri S, Corbella S. Ten years follow-up retro- indicators and severity of peri-implantitis using mixed model analyses. J Clin
spective study on implant survival rates and prevalence of peri-implantitis in Periodontol 2011;38:285-92.
implant-supported full-arch rehabilitations. Clin Oral Implants Res 2019;30: 41. Konstantinidis IK, Kotsakis GA, Gerdes S, Walter MH. Cross-sectional study
252-60. on the prevalence and risk indicators of peri-implant diseases. Eur J Oral
Implantol 2015;8:75-88.
24. Friberg B, Jemt T. Rehabilitation of edentulous mandibles by means of
42. Souza AB, Tormena M, Matarazzo F, Araújo MG. The influence of peri-
osseointegrated implants: a 5-year follow-up study on one or two-stage
implant keratinized mucosa on brushing discomfort and peri-implant tissue
surgery, number of implants, implant surfaces, and age at surgery. Clin
health. Clin Oral Implants Res 2016;27:650-5.
Implant Dent Relat Res 2015;17:413-24.
43. Perussolo J, Souza AB, Matarazzo F, Oliveira RP, Araújo MG. Influence of the
25. Mori G, Oda Y, Sakamoto K, Ito T, Yajima Y. Clinical evaluation of full-arch
keratinized mucosa on the stability of peri-implant tissues and brushing
screw-retained implant-supported fixed prostheses and full-arch telescopic-
discomfort: A 4-year follow-up study. Clin Oral Implants Res 2018;29:
retained implant-supported fixed prostheses: A 5-12 year follow-up retro-
1177-85.
spective study. Clin Oral Implants Res 2019;30:197-205.
44. Schrott AR, Jimenez M, Hwang JW, Fiorellini J, Weber HP. Five-year eval-
26. Riemann M, Wachtel H, Beuer F, Bolz W, Schuh P, Niedermaier R, et al.
uation of the influence of keratinized mucosa on peri-implant soft-tissue
Biologic and technical complications of implant-supported immediately
health and stability around implants supporting full-arch mandibular fixed
loaded fixed full-arch prostheses: An evaluation of up to 6 years. Int J Oral
prostheses. Clin Oral Implants Res 2009;20:1170-7.
Maxillofac Implants 2019;34:1482-92.
45. Lin WS, Eckert SE. Clinical performance of intentionally tilted implants
27. Heitz-Mayfield LJ, Aaboe M, Araujo M, Carrión JB, Cavalcanti R, Cionca N,
versus axially positioned implants: A systematic review. Clin Oral Implants
et al. Group 4 ITI Consensus Report: Risks and biologic complications
Res 2018;29(Suppl 16):78-105.
associated with implant dentistry. Clin Oral Implants Res 2018;29(Suppl 16):
46. Francetti L, Corbella S, Taschieri S, Cavalli N, Del Fabbro M. Medium- and
351-8.
long-term complications in full-arch rehabilitations supported by upright and
28. Mombelli A, Lang NP. Clinical parameters for the evaluation of dental tilted implants. Clin Implant Dent Relat Res 2015;17:758-64.
implants. Periodontol 2000 1994;4:81-6. 47. Acocella A, Ercoli C, Geminiani A, Feng C, Billi M, Acocella G, et al. Clinical
29. Ata-Ali J, Flichy-Fernández AJ, Alegre-Domingo T, Ata-Ali F, Palacio J, evaluation of immediate loading of electroeroded screw-retained titanium
Peñarrocha-Diago M. Clinical, microbiological, and immunological aspects of fixed prostheses supported by tilted implant: a multicenter retrospective
healthy versus peri-implantitis tissue in full arch reconstruction patients: a study. Clin Implant Dent Relat Res 2012;14(Suppl 1):e98-108.
prospective cross-sectional study. BMC Oral Health 2015;15:1-10. 48. Doornewaard R, Jacquet W, Cosyn J, De Bruyn H. How do peri-implant
30. Kanao M, Nakamoto T, Kajiwara N, Kondo Y, Masaki C, Hosokawa R. biologic parameters correspond with implant survival and peri-implantitis? A
Comparison of plaque accumulation and soft-tissue blood flow with the use critical review. Clin Oral Implants Res 2018;29:100-23.
of full-arch implant-supported fixed prostheses with mucosal surfaces of 49. Coli P, Christiaens V, Sennerby L, Bruyn HD. Reliability of periodontal
different materials: a randomized clinical study. Clin Oral Implants Res diagnostic tools for monitoring peri-implant health and disease. Periodontol
2013;24:1137-43. 2000 2017;73:203-17.
31. Abi Nader S, Eimar H, Momani M, Shang K, Daniel NG, Tamimi F. Plaque 50. Bidra AS, Daubert DM, Garcia LT, Kosinski TF, Nenn CA, Olsen JA, et al.
accumulation beneath maxillary all-on-4 implant-supported prostheses. Clin Clinical practice guidelines for recall and maintenance of patients with
Implant Dent Relat Res 2015;17:932-7. tooth-borne and implant-borne dental restorations. J Prosthodont
32. De Bruyn H, Bouvry P, Collaert B, De Clercq C, Persson GR, Cosyn J. Long- 2016;25(Suppl 1):S32-40.
term clinical, microbiological, and radiographic outcomes of Brånemark™
implants installed in augmented maxillary bone for fixed full-arch rehabili-
tation. Clin Implant Dent Relat Res 2013;15:73-82. Corresponding author:
33. Maeda T, Mukaibo T, Masaki C, Thongpoung S, Tsuka S, Tamura A, et al. Dr Konstantinos Chochlidakis
Efficacy of electric-powered cleaning instruments in edentulous patients with Department of Prosthodontics
implant-supported full-arch fixed prostheses: a crossover design. Int J Eastman Institute for Oral Health, University of Rochester
Implant Dent 2019;5:1-8. 625 Elmwood Ave
34. Schuldt Filho G, Dalago HR, Oliveira de Souza JG, Stanley K, Jovanovic S, Rochester, NY 14620
Bianchini MA. Prevalence of peri-implantitis in patients with implant- Email: kchochlidakis@urmc.rochester.edu
supported fixed prostheses. Quintessence Int 2014;45:861-8.
35. Isaksson R, Becktor JP, Brown A, Laurizohn C, Isaksson S. Oral health and Copyright © 2020 by the Editorial Council for The Journal of Prosthetic Dentistry.
oral implant status in edentulous patients with implant-supported dental https://doi.org/10.1016/j.prosdent.2020.12.011

Chochlidakis et al THE JOURNAL OF PROSTHETIC DENTISTRY

You might also like