1. Corticosteroid hormone produced by adrenal cortex is ?

A. Glucocorticoids
B. Mineralocorticoids
C. Adrenal androgens
D. All of the above

2. Which of the following is produced by adrenal cortex ?

A. Dehydroepiandrosterone
B. Aldosterone
C. Cortisol
D. All of the above

3. Which of the following is located outermost in adrenal gland ?

A. Zona glomerulosa
B. Zona fasciculata
C. Zona reticularis
D. Adrenal medulla

4. Which of the following statements is true ?

A. Mineralocorticoid synthesis occurs in zona glomerulosa
B. Glucocorticoid synthesis occurs in zona fasciculata
C. Adrenal androgen synthesis occurs in zona reticularis
D. All of the above

5. Action of mineralocorticoids include all except ?

A. Immune responses
B. Blood pressure
C. Vascular volume
D. Electrolytes

6. Basic substrate for steroidogenesis is ?

A. Triglycerides
B. Cholesterol
C. Amino acids
D. Polysaccharides

7. Physiologically active form of cortisol is ?

A. Free cortisol
B. Protein-bound cortisol
C. Cortisol metabolites
D. All of the above

8. Steroid inactivation occurs in ?

A. Liver
B. Lung
C. Kidney
D. All of the above

9. he plasma level of ACTH peak ?

A. Just prior to waking up
 B. Just after waking up
C. Before sleeping
D. After meals

10. Normal pulsatile, circadian pattern of ACTH release is regulated

by ?
A. Corticotropin-releasing hormone
B. Free plasma cortisol concentration
C. Sleep-wake cycle
D. All of the above

11. Cushing’s disease refers to ?

A. Adrenal cortisol-secreting tumor
B. Exogenous ACTH tumor
C. ACTH-producing pituitary tumor
D. All of the above

12. Cushing’s syndrome refers to ?

A. Exogenous ACTH tumor
B. Adrenal tumor
C. Pituitary ACTH-secreting tumor
D. All of the above

13. Which of the following can cause ‘Ectopic ACTH syndrome’ ?

A. Oat cell bronchogenic carcinoma
B. Carcinoid tumors of thymus, pancreas, ovary
C. Medullary carcinoma of thyroid
D. All of the above

14. Which of the following is the commonest feature of ‘Cushing’s

syndrome’ ?
A. Centripetal obesity
B. Hypertension
C. Hirsutism
D. Proximal myopathy

15. Most common cause of Cushing’s syndrome is ?

A. Iatrogenic administration of steroids
B. Adrenal macronodular hyperplasia
C. Adrenal micronodular dysplasia
D. Adrenal neoplasia

16. Increased production of aldosterone occurs in secondary

aldosteronism in response to ?
A. Activation of sympathetic system
B. Activation of parasympathetic system
C. Activation of renin-angiotensin system
D. All of the above
17. Adrenals is a frequent site for which of the following chronic
granulomatous diseases ?
A. Tuberculosis
B. Histoplasmosis
C. Coccidioidomycosis
D. All of the above

18. Which of the following is the most frequent presentation in adrenal

insufficiency ?
A. Weakness
B. Pigmentation of mucous membranes
C. Salt craving
D. Diarrhea

19. What proportion of total glucocorticoid dose should be given in

morning in the treatment of adrenal
insufficiency ?
A. One third
B. One half
C. Two third
D. Three fourth
20. Which of the following favors a diagnosis of primary adrenocortical
insufficiency ?
A. Dehydration
B. Hyponatremia
C. Hyperkalemia
D. All of the above