Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS

1. A formula for a cough syrup contains 1/8 5. The pediatric dose of cefadroxil is 30
gr of codeine phosphate per teaspoonful. How mg/kg/day. A child is receiving a daily dose of
many grams of codeine phosphate should be two teaspoonfuls of a pediatric cefadroxil
used in preparing 2 pints of the cough syrup? suspension based on the body weight. If the
a. 2.30 g child's weight is 18.3 lb, How many milligrams
b. 6.43 g of the drug is the child receiving in each dose?
c. 1.54 g a.250mg
d. 0.91 g b.120 mg
e. 1.03 c.375 mg
d. 300 mg
2. How many grams of KSCN should be e. 200 mg
used in compounding the following
prescription? 6. A physician prescribes tetracycline
Rx Potassium Thiocyanate suspension for a patient to be taken in doses
Aromatic elixir aa qs of two teaspoonfuls 4x a day for four days,
Make a solution to contain 0.2 g?tsp and then one teaspoonful 4x a day for two
Disp. 150 mL days. How many mL of the suspension should
Sig: 5 mL in water daily be dispensed to provide the quantity for the
a. 6 g prescribed dosage regimen?
b. 8 g a. 200 mL
c. 2.5 g b. 250 mL
d. 12.5 g c. 500mL
e. 7.25 d.120 mL
e. 300 mL
3. How many gr of dihydrocodeinone should
be used in compounding the following 7. If a potassium chloride elixir contains 40
prescription? milliequivalents of potassium ion in each 30
Rx Dihydrocodeinone gr 1/12 /tsp mL of elixir, how many mL will provide 15
Hydriodic acid syrup milliequivalents of potassium ion to the
Cherry syrup aa fl oz Iii patient?
Sig: Tsp every 2 hr for cough a. 10.25 mL
a. 6 b. 15.00 mL
b. 3 c. 11.25 mL
c. 12 d.25.00mL
d. 1.5 e. 10.75 mL
e. 4
8. What is the percentage of alcohol in the
4. A patient has been instructed to take 15 following precription?
mL of Vistarel® (hydroxyzine pamoate) oral Rx Chloroform spirit 50.0 mL (90% alcohol)
suspension every six hours four doses daily. Aromatic elixir 150.0 mL (21% alcohol)
How many days will two fluidounce bottles of Terpin hydrate elixir 300.0 mL
suspension last? (45% alcohol)
a. 10 Sig. 5 mL for cough
b. 5 a. 42.3 %
c.11 b.56.75%
d.6 c.18.2%
e.8 d. 38.7%
e.39.7%
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PHARMACEUTICAL CALCULATIONS

10. If 5 mL of a 20% w/v aqueous solution of b. 0.820 mg

furosemide is diluted to 10 mL, what will be c. 0.250 mg
the final strength of furosemide? d. 0.500 mg
a. 5 e. 0.725 mg
b. 10
c. 15 15. How many mL of Reglan injection
d. 30 (5mg/mL) should be given to a patient who is
e. 20 eight months old? The usual dose of
metoclopramide HCl is 10 mg.
11. How many milliliters of a 1:20 v/v solution a. 1.0 mL
of methyl salicylate in alcohol can be made b. 2.0 mL
from 100 mL of 2% v/v solution? c. 0.1 mL
a. 25 d. 0.2 mL
b.38 e. 0.01 mL
c.40
d.30 16. The usual dose of Tylenol® is 500 mg qid,
e.20 prn fever. If Tylenol® is to be prescribed for a
two-month old baby, how many mL of
12. A physicians order for an IV infusion for a Tylenol® drops (80 mg/mL) should be given
patient weighing 110 lbs calls for a 0.25 mEq as a single dose to this patient?
of KCl per kg of body weight to be added to a. 0.08 mL
500 mL of D5W. How many mL of a sterile b. 1.10 mL
solution containing 50 mEq of KCl per 10 mL c. 0.9 mL
should be used in preparing the infusion? d. 0.05 mL
a. 10.0 mL e. 0.8 mL
b. 1.0 mL
c. 1.5 mL 16. Rx
d. 2.5 mL Keflex® caps 500mg
e. 3.0 mL Sig; 1 cap bid, 7 days
If the pharmacist has only 250 mg capsules
13. A medication order for an IV infusion for a in the inventory, how many capsules should
patient weighing 143 lbs calls for a 0.25 mEq be given to the patient?
of ammonium chloride per kg body weight to a. 14
be added to 500 mL 5% dextrose injection. b. 7
How many mL of a sterile solution containing c. 21
100 mEq of ammonium chloride per 25 mL d. 28
should be used in preparing the infusion? e. 24
a. 6.2 mL
b. 4.1 mL 17. If two pints of a guaifenesin elixir is
c. 8.0 mL present in the inventory, how many 4-fluid
d. 9.8 mL ounces prescription can be filled?
e. 5.3 mL a. 12
b. 10
14. Prochlorperazine is prescribed for a child c. 5
whose date of birth is 05/21/2001. If the usual d. 8
adult dose is 5 mg, how many mg would be e. 6
administered to the child? The prescription is
dated 01/01/2005. 18. An IV flow rate is set at 48gtt/mL. The
a. 0.625 mg infusion set has a drop factor of 15gtt/mL.
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PHARMACEUTICAL CALCULATIONS

How many mL of IV fluid will be infused in 8 b. 6.2

hrs? c. 4.8
a. 1536 mL d. 12
b. 2395 mL e. 4.6
c. 1050 mL
d. 950 ml 24. How many apothecary ounces are present
in lbs iiss?
19. What is the percentage (w/w) of coal tar in a. 30
the finished product in when 10 g of coal tar is b. 42
mixed with 200 g of a 5% coal tar ointment? c. 16
a. 4 d. 9.5
b. 6.8 e. 22
c.9.5
d. 11.0 25. Zovirax® tablets, containing the antiviral
drug, acyclovir, are given in a dose of 80
20. A physician ordered: “Benadryl® 50 mg mg/kg for 5 days for treating chickenpox. If the
PO h.s. p.r.n.” If the available Benadryl® patient weighs 120 lbs, how many ounce(s) of
(diphenydramine HCl) elixir contains 2.5 mg acyclovir would the patient consume if he has
drug in each mL, how many teaspoons will be to take the full dose prescribed?
administered to the patient? a. 1.3
a. 4 b.0.73
b. 6 c. 16
c. 2 d. 9.5
d. 5 e. 3.5
e. 3
26. If a physician orders "Lanoxin® 0.25 mg
21. Fer-in-sol® drops contain 75 mg ferrous p.o. q.d.", how many mL of Lanoxin® (digoxin)
sulfate 0.60 mL of the solution. If a pharmacist elixir containing 50 mcg of digoxin per mL
dispensed 60 mL of the solution, how many should be used?
grams of ferrous sulfate were dispensed?'
a. 10 a. 15 mL
b. 7.5 b. 10 mL
c. 15 c. 8 mL
d. 20 d. 5 mL
e. 9 e. 3 mL

22. If a patient needs one teaspoonful of 27. A patient has been instructed to take
Amoxil® oral liquid 3x a day for seven days, Vistarel® (hydroxyzine pamoate) oral
how many fluidounces of medication should suspension every four hours for four doses
the pharmacist dispense? daily. How many days will a 6 -fluidounce
a. 12 bottle of the suspension last?
b. 8 a. 2
c. 6 b. 4.5
d. 3.5 c. 7
e. 7 d. 12
e. 6
23. How many liters of 2% w/v Iodine tincture
can be made from 78 g of iodine? 28. Rx
a. 3.9 Phenergan tablets 12.5 mg
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PHARMACEUTICAL CALCULATIONS

Dispense 14 tablets ointment, and 300 grams of white petrolatum

Sig; q hs (diluent)?
If the pharmacist dispensed 25 mg tablets of a. 2.3%
phenergan, how many tablets should the b. 4.5%
patient take at bedtime? c. 7.8%
d. 5.23%
a. 2 e. 2.3 %
b. 1
c. 1/2 33. If a pharmacist dispenses cephalexin 250
d. 1/4 mg capsules for the prescription below, what
e. 1/3 directions should be provided to the patient?
Rx
29. Rx Cephalexin capsules 500 mg
Atropine sulfate 0.2 mg Sig; 1 cap tid, 10 days
Sig; Administer IM a. 2 caps 3x a day for 10 days
If the available atropine vial reads gr 1/150 per b. 3 caps 2x a day for 5 days
mL, how many mL of the injection should be c. 2 caps 4x a day for 8 days
administered? d. 3 caps once a day for 15 days
a. 1.20 e. 2 caps 2x a day for 14 days
b. 0.75
c. 1.43 34. Spironolactone tablets are available in 25
d. 0.465 mg strength, but a drug orders comes for 150
e. 1.72 mg dose. How many tablets should be
dispensed to last for 5 days?
30. A medication order calls for Prostigmin® a. 6
0.25 mg IM. The only supply of Prostigmin® is b. 12
1:200 solutions. How many mL of this solution c. 20
would contain 0.25 mg? d. 30
a. 0.05 mL e. 25
b. 0.75
c. 1.43 35. Calculate the (w/w) of coal tar in the
d. 0.465 finished product when 8 grams of coal tar is
e.1.72 mixed with 120 grams of a 4% coal tar
ointment.
31. What is the percentage (w/w) of a.10
hydrocortisone in the finished product when b. 15
50 mg of hydrocortisone is mixed with 10 c. 20
grams of Cortril® ointment containing 1% d. 30
hydrocortisone? e. 25
a. 0.05 mL
b. 0.5 mL 36. If a 10 mL vial of insulin contains 200 units
c. 5 mL of insulin per milliliter, and a patient is required
d. 0.25 mL to receive 20 units twice daily, how many days
e. 0.005 mL will the product last the patient?
a. 20 days
32. What is the percentage of ZnO in an b. 30 days
ointment prepared by mixing 200 grams of an c. 35 days
8% ZnO ointment, 150 grams of a 12% ZnO d. 50 days
e. 45 days
 Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS

42. If Lactulose Syrup USP contains 10 g

37. A patients receives 30 mL of heparin lactulose in 15 mL of the syrup, how many mL
every hour. If there are 40 units in each would provide the equivalent of 1.33 g of
milliliter, how many units does the patient lactulose?
receive in 24 hours? a. 2
a.30, 200 b. 5
b.28, 000 c. 10
c. 12,440 d. 6
d. 21,880 e. 4
e. 14, 250
43. In the calibration of a medical dropper, 2
38. How many mL of a 1:500 v/v solution of mL of a pediatric drop solution was found to
methyl salicylate in alcohol can be made from give 48 drops. If it is desired to administer 0.3
100 mL of 5 % v/v solution? mL of the medication to a baby, approximately
a. 2 500 how many drops should be given?
b. 250 a. 1
c. 5000 b. 3
d. 1500 c. 5
e. 3500 d. 8
e. 2
39. Calculate the IV flow rate for 500 mL D5W
to run for 8 hours. The drop factor is 60 44. If an injectable solution contains 25 mcg of
gtt/mL. a drug substance in each 0.5 mL, how many
a. 70 gtts/min mL will be required to provide a patient with
b. 65 gtts/min 0.25 mg of the drug substance?
c. 63 gtts/min a. 15 mL
d. 54 gtts/min b. 10 mL
e. 72 gtts/min c. 5 mL
d. 1 mL
40. If a vial of gentamycin contains 80 mg of e. 20 mL
drug in 2 mL, how many mcg of the drug are
present in 0.02 mL 45. A certain elixir contains 0.325 g of the
a. 800 active ingredient per teaspoonful. At PhP
b. 350 15.35 per lb, what is the cost (PhP) of the
c.26 active ingredient needed to make one gallon
d. 655 of the elixir?
e. 260 a. 6.41
b. 8.32
41. Atenolol is available in strength of 50 mg. c. 24.06
If a prescription is written for 100 mg daily for d. 12.05
three weeks as directed, how many tablets e. 9.36
should be dispensed?
a. 20 46. If a 500 mL of ferric chloride solution
b. 42 weighs 650 g, what is its specific gravity?
c. 21 a. 1.3
d. 60 b. 0.7692
e.45 c. 1.45
d. 0.8451
e. 0.93
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PHARMACEUTICAL CALCULATIONS

47. What is the density of a metal, 10 mL of 53. If 500 mL of mineral oil is used to prepare
which weighs 5450 mg? a liter of mineral oil emulsion, how many
a. 1.106 grams of oil having a specific gravity of 0.87
b. 0.670 would be used in the preparation of 1 gallon of
c. 0.545 emulsion?
d. 10.5 a. 1780.1
e. 0.626 b. 1646.5
c. 245.30
d. 1100.4
48. Calculate the specific volume of a syrup if e. 1546.5
20 mL of it weighs 35 grams.
a. 1.75 54. If 200 mg of propylhexedrine, a liquid
b. 0.57 having a specific gravity of 0.85, are used in a
c. 1.86 single nasal inhaler, how many millimeters of
d. 0.72 drug would be used in the manufacturing of
e. 0.76 1000 inhalers?
a. 294
49. What is the specific volume of sulphuric b. 308
acid having a specific gravity of 1.826? c. 78
a. 0.548 d. 402
b. 1.800 e. 113
c. 0.431
d. 2.135 55. The inhalant dose of amyl nitrate is 0.25
e. 0.673 mL, express the dose in minims.
a. 3.50
50. What is the weight of 3.5 liters of alcohol b. 4.06
having a specific gravity of 0.835? c. 2.55
a. 4.19 g d. 0.88
b. 2922.5 e. 3.33
c. 2.92
d. 3102 g 56. Given a solution of potassium
e.454.3 permanganate prepared by dissolving twenty
0.2 g tablets in enough purified water to make
51. How many grams would 1 pint of HCl two liters of resulting solution, what is the
weigh (sp. gr. 1.16)? percentage strength of the solution?
a. 345 a. 2.0 %
b. 675 b. 4.0%
c. 549 c. 0.2 %
d. 980 d. 0.4%
e. 560 e. 20.0%

52. What is the volume (in millimeters) of 2 kg 57. In problem number 56, what is the ratio
of sulfuric acid with a specific gravity of 1.83? strength of KMnO4 solution?
a. 1093 a. 1:500
b. 2095 b. 1 :50
c. 1205 c. 1:250
d.1830 d. 1: 20
e.1003 e. 1:350
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d. 0.5 %
58. Express a patient's uric acid level of 6.0 e.0.05%
mg/dL in terms of mg%.
a. 12 64. If 600 mg of sodium chloride is dissolved
b. 6 in enough water to make three pints of NaCl
c.0.6 solution, what is its concentration in % w/v?
d. 60 a. 6%
e. 16 b. 4%
c. 0.04%
59. If a 10 mL serum ampule is determined to d. 0.6%
contain 9 mg of glucose, express the e. 40%
concentration of glucose as mg%.
a. 90 65. What is the concentration of 0.04% (w/v)
b. 9 NaCl solution in ratio strength?
c. 18 a. 1:2500
d. 6 b. 1:166.67
e. 0.9 c. 1:250
d. 1:400
60. What is the proof strength of a 40% e. 1: 225
alcohol?
a. 40 66. What is the % w/w concentration of a 10%
b. 60 w/v cough syrup having a specific gravity of
c. 75 1.120?
d. 80 a. 8.93%
e. 65 b. 11.20%
c. 12.50%
61. How many proof gallons does 20 wine d. 7.15%
gallons of a 15% v/v alcohol measure? e. 9.85%
a. 6
b. 12 67. If a commercially available insulin
c. 3 preparation contains 2 ppm of proinsulin, how
d.20 many grams of pro insulin would be contained
e. 4 in a 10 mL vial of insulin?
a. 0.00003
62. A glucometer shows that a patient's blood b. 0.004
serum contains 135mg% glucose. Express c. 0.0007
this value in % w/v. d. 0.0002
a. 0.135% e. 0.0006
b. 1.35%
c. 0.27% 68. Express the concentration of aromatic
d. 13.5% water in a ratio strength prepared by mixing 2
e. 3.15% mL of aromatic oil in 450 mL distilled water.
a. 1:200
63. The fluoride concentration in drinking b. 1:312
water is 0.5 ppm. Express this concentration c. 1: 227
in percent. d. 1:225
a. 0.005% e. 1: 335
b. 0.00005%
c. 5%
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70. Calculate the ratio strength of a sulfur b. 16

ointment which contains two oz. of sulfur in c. 12
thirty kilograms of ointment. d. 10
a. 1:1058 e. 15
b. 1: 2030
c. 1: 3065 76. A pharmaceutical manufacturer has 4500
d. 1: 1150 gallons of 95% (v/v) alcohol. How many proof
e. 1: 1008 gallons are represented by this quantity?
a. 8050
71. What is the percent strength of a 1:2000 b. 9250
potassium chloride solution? c. 1450
d. 8550
e. 8250

a. 0.5 77. The cost of 100 antacid tablets is PhP

b. 1.8 68.50. What should be the selling price per
c. 20 hundred tablets to yield a 40% gross profit on
d. 0.05 the selling price?
e. 2.25 a. 114
b. 210
72. Calculate the weight in grams of two pints c. 75
of syrup if its specific gravity is 0.975. d. 88
a. 970.26 g e. 107
b. 498.10 g
c. 922.35 g
d. 670.05 g 78. A bottle of (30's ) of analgesic tablet sold
e. 899. 45 g at PhP 75.00, thereby yielding a gross profit of
30% on the cost. What was the cost of the
73. If five gallons of lotion contains one pound bottle of tablets?
of talc, what is the percentage strength? a. 62.35
a. 2.4 % b. 57.70
b. 6.7% c.68.50
c. 8.3 % d. 52.00
d. 10.5 %
e. 3.6% 79. A prescription item costs a pharmacist
PhP 45.00. Upon mark up of 35% on the cost
74. What is the % w/v concentration of a plus a professional fee of PhP 30.00, what
solution made by mixing 35 g of main would be the price of the dispensed
ingredients in 500 g of vehicle (sp. gr. 1. prescription?
2000)? a. 85.50
a. 1.25% b. 92.25
b. 7.75% c. 78.50
c. 16.2% d. 90.75
d. 8.4 % e. 88.50
e. 8.3 %
80. How many chloramphenicol capsules,
75. How many proof gallons are contained in each 250 mg are needed to provide 25 mg per
8 wine gallons of 75% (v/v) alcohol? kg per day for 1 week for a person weighing
a. 20 175 lbs?
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a. 43 e. 80 mL
b.38
c. 65 86. How many 2-fluid ounce bottles of a cough
d. 56 syrup can be obtained from one gallon of the
e. 72 cough syrup?
a. 50
81. How many grams of sodium bicarbonate b. 45
(MW= 84g/mole) should be used in preparing c. 64
a liter of solution which is to contain 8 mEq of d. 27
sodium bicarbonate in each 10 mL? e. 56
a. 67.2 g
b. 57.1 g 87. From the following Ipecac Syrup, calculate
c. 73 g the amount of Ipecac needed to prepare
d. 90 g enough syrup to fill one hundred 15-mL
e. 52.4 g prescription bottles:

82. How many grams of KCl (MW=74.54 Ipecac fluidextract 70 mL

g/mole) should be used in making a liter of Glycerin 100 mL
solution containing 5 mEq of potassium per Syrup qs 1000 mL
mL? a. 100
a. 372.7 g b. 105
b. 186.35 g c. 90
c. 435 g d. 120
d. 74.54 g e. 80
e. 433.3 g
88. In what portion should 10% and 20% coal
83. Ether has a specific gravity of 0.72. How tar ointments be mixed to prepare a 5%
many milliliters will 60 grams measure? ointment?
a. 72 a. 3 parts/5parts
b. 43 b. 5 parts/3 parts
c. 83 c. 2 parts/ 6 parts
d. 96 d. 1 part/ 3 parts
e. 91 e. 5 parts/ 2 parts

84. What bis the % w/w of a 75% preparation ( 89. What is the percentage strength of a 1:
sp. gr. 1.085)? 10,000 potassium permanganate solution?
a. 78 a. 0.01%
b. 69 b. 1.10%
c. 81 c. 20%
d. 62 d. 0.5%
e. 74 e. 10.0%

85. The patient is to take 1 teaspoonful of 90. Calculate the ratio strength of a mixture
medication bid for 1 week. How many mL of prepared by mixing 2 oz of ZnO in one
the medication should the patient buy? kilogram white petrolatum.
a. 60 mL a. 1:500
b. 70 mL b. 1: 35.78
c. 120 mL c. 1: 18.62
d. 150 mL d. 1: 23.97
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e. 1:36.78 e.80

91. How many liters of a 95% sulfuric acid 96. A household measure of 1 wineglass is
having a specific gravity of 1.82 should be equivalent to:
used in preparing three liters of 10% sulfuric a. 2 fluidounces
acid? b. 4 fluidounces
a. 0.17 c. 8 fluid drams
b. 2.1 d. 4 fluid drams
c. 0.32 e. 8 fluidounces
d. 0.54
e. 0.22 97. How many teaspoonfuls would be
prescribed in each dose of an elixir if 6 fluid
92. What is the strength of sodium chloride ounces contained 36 doses?
solution obtained by evaporating 550 grams of a. 4
a 12% solution to a final weight of 150 grams? b. 2
c. 1
d. 5
a. 63% e. 3
b. 38%
c. 21% 98. If three pounds of a substance would be
d. 34% used in preparing 2000 tablets, how many
e. 57% milligrams are represented in each tablet?
a. 681
93. How many millilitres of a 50% w/v solution b. 725
should be mixed with 2175 mL of a 10% w/v c. 850
solution to make a 20% w/v solution? d. 1250
a. 800 mL e. 632
b.615 mL
c.415 mL 99. If the dose of the drug is 1/16 grains, how
d.725 mL many doses are contained in two drams?
e. 650 mL a. 2045
b. 1920
94. Calculate the number of mL of water c. 1560
needed to be added to a mixture of 700 mL of d. 980
55% v/v alcoholic solution and enough 20% e. 1430
v/v alcoholic solution to make 1000 mL if the
final solution is to be 40% alcoholic solution. 100. How many mEq of Na+ are in 200 mL
a. 75 mL NSS (MW= 58.5)?
b. 300 mL a. 15.4
c. 55 mL b. 30.8
d. 225 mL c. 58.5
e. 125 mL d. 9.0
e. 45.2
95. If a dose of 1/600 gr is prescribed, its
equivalent dose in microgram is: 101. A 500 mL infusion bottle contains 2.0
a. 10 mEq Calcium per mL. How much calcium (At.
b.100 Wt. Ca=40) in grams does it contain?
c.120 a. 10
d. 60 b. 40
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PHARMACEUTICAL CALCULATIONS

c.30 a. 7
d. 20 b. 14
e. 50 c. 15
d. 20
102. Given the following prescription: e. 12
Rx
V-Cillin® K 250 mg/tablet 106. Rx
Disp. # 28 Tagamet 300 mg
Sig: 1 tab q 6h until finished Sig : i bid, 15 days
How many days will the medication last? How many tablets should the patient
a. 5 buy to complete the medication?
b. 10 a. 30
c. 7 b. 45
d. 6 c. 15
e. 8 d. 50
e. 35
103. How many mg of the active ingredient is
present in this preparation? 107. Rx
Dimenhydrinate
Rx Pantothenic acid aa 30 mg
Neosynephrine® 2.5% Thiamne HCl 10 mg
10 mL Calcium carbonate 100 mg
Sig: I gtt os tid M ft. Cap DTD #12
a. 25 Sig: i cap qid for nausea
b. 250 How many mg of dimenhydrinate is needed to
c. 2.5 compound this prescription?
d. 0.25 a.1400
e. 2500 b.550
c.360
104. Rx d.405
Neosynephrine® 2.5% e. 300
10 mL
Sig: I gtt os tid 108. Pediaprofen® pediatric suspension
If the dropper to be used in the above contains 80 mg ibuprofen in 5 mL of
prescription is calibrated to deliver 20 gtts per suspension. While taking 2.5 mL of this
mL, how many doses are contained in the medication, the patient spilled 1 mL of the
preparation? suspension. How many milligrams of
a. 20 ibuprofen did the patient spill?
b. 50 a. 24.0
c. 300 b. 37.0
d. 200 c.30.0
e. 150 d.40.0
e.29.0
105. Rx
Corticosporin otic solution 109. The cost of an alcohol is P250.00 per
15 mL proof gallon. What is the cost of 10 wine
Sig: iv gtt ad qid gallons of alcohol marked “190 proof”?
If 1 mL. of the solution contains 15 gtts, how a. P4500.00
many days will the medication last? b. P4750.00
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c. P5000.00 e.0.20
d. P5250.00
e. P4250.00 114.What is the Sodium Chloride equivalent
(E) of Benzalkonium chloride?
110. A drum contains 60 proof gallons of 40% a. 0.19
alcohol. How much would 3 drums cost if the b. 0.18
alcohol is sold at P60.00 per wine gallon? c. 0.17
a.P14000.00 d. 0.16
b.P15000.00 e. 0.20
c.P14500.00
d.P13500.00 115. Convert 37˚Celsius to Farenheit
e.13000.00 a. 96.8
b. 86.9
111. A formula for an ointment requires 70g of c.98.6
an emulsifier blend consisting of Tween40 and d.69.8
Span20. If the required HLB is 11.6,how many
grams of each emulsifier should be used in 116. Convert 212˚F or farenheit to centigrade
preparing the ointment? HLB of Span20= 8.6, a.100
Tween 40=15.6 b.95
c.90
d.105
a. 23 g of Tween40 and 46.7 g of Span20 e.110
b. 17.5 g of Tween40 and 52.5 g of Span20
c. 30.0 of Tween40 and 40.0 g of Span20 117. What is the dose for a child whose body
d. 40.0 g of Tween40 and 30.0 g of Span20 surface area is 0.64m2 if the adult dose is
e. 33.0 g of Tween40 and 25.0 g of Span20 a. 208 mg
b. 120 mg
112. Rx c. 31 mg
Atropine 1%# d. 162 mg
Boric acid q.s. e. 140 mg
Purified water ad 50 mL
Make Isotonic solution 118. What is the cost of 15.0 kg of glycerine
Sodium chloride equivalent (E) (sp. Gr. =1.25) if it is sold at 175.00 per kg?
Atropine Sulfate =0.12 a. 4394.75
Boric Acid= 0.52 b.4943.75
How many grams of boric acid ahould c.4439.75
be used in compounding the prescription? d.4444.95
a. 1.33 g e.4344.75
b. 0.75 g
c. 0.13 g 119. A prescription calls for 1500 mL of D5W
d. 0.91 g to be administered over a 10 hour period
e. 0.80 g using a which delivers 15 drops/mL, what is
the rate in drops per minute?
113. What is the dissociation factor (1) of a. 12.50 drops/min
Benzalkonium chloride? b. 35 drops/min
a. 0.19 c. 40 drops/min
b.0.18 d. 42.5 drops/min
c. 0.17 e. 45 drops/min
d. 0.16
 Philippine Association of Colleges of Pharmacy PINK

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120. 250 mg of Amoxicillin is added to 500 mL 125. How many grains of potassium
of D5W and the rate of administration is 125 permanganate should be dissolve din 1.5
mg per hour, what will be the rate of flow in pints of water to make 7.5% (w/v) solution?
drops per minute if the infusion set delivers 15 a.818.9
drops/min? b. 818.6
a. 12.50 drops/min c. 820.7
b. 13.00 drops/min d. 808.7
c. 13.50 drops/min e. 881.1
d. 14.00 drops/min
e.14.50 drops/min 126. How much NaCl should be used in
compounding the prescription?
121. What is the daily dose of Amoxicillin for a.0. 330 g
the last 2 days? b.0. 320 g
a. 1250 mg c. 0.325 g
b. 500 mg d. 0.335 g
c, 750 mg e. 0.352 g
d. 1000 mg
e. 950 mg 127. A pharmacist adds 20 nmL of Calcium
Chloride Injection labeled 4 mEq/ mL to a 500
122. If the dropper calibrates 20 drops/mL, mL bottle of D5W injection. What is the
how many drops should be administered? concentration of calcium chloride expressed
as mg/mL in the final mixture? (CaCl.H20
MW=147)
a. 4 drops a. 12.13
b. 8 drops b. 13.12
c. 6 drops c.11.23
d. 5 drops d.11.31
e. 7 drops e.13.11

123. How many pints of high alcoholic elixir is 128. A person is to receive 4 mEq of sodium
required to prepare the same amount of elixir? chloride per kg body weight. If the person
a. 5.9 weighs 165 lbs., how many mL of Normal
b.3.4 Saline Solution should be administered?
c.7.2 (NaCl MW= 58.5 g/mole)
d.4.7 a.1900 mL
e. 6.4 b.1800 mL
c. 2000 mL
124. What is the percentage (w/v) of dectrose d.1950 mL
in a mixture of 6000 mL of 5% (w/v) dextrose e. 1750 mL
solution and 750 mL of 50% (w/v) dextrose
solution? 129. A physician prescribes 10 million units of
a. 1.0% Benzyl Penicillin Na daily for 1 week. If 1 ug of
b. 10.0% Benzyl Penicillin Na equals 1.6 unit, how
c. 1.5% many tablets each containing 500 mg will
d. 15.0% provide the benzyl penicillin Na for the
e. 10.1% prescribed dosage regimen?
a. 17.5 tablets
b. 12.5 tablets
c. 15 tablets
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d. 10 tablets c. 10.1
e. 14 tablets d. 6.6
e. 6.9
130. A physician prescribed 225 U of insulin to
be added to 250 mL of D5W in treating a 135. How many 96.0% of sulfuric acid having
patient with severe diabetic acidosis. How a specific gravity of 1.54 is required to make
much U-100 insulin should be used? 500 mL of diluted sulfuric acid (10.0% w/v)?
a. 0.225 mL a. 27.8 mL
b. 2.25 mL b. 26.4 mL
c. 22.5 mL c. 23.6 mL
d. 225.0 mL d. 28.3 mL
e. 25.2 mL e. 24.6 mL

131. The dissociation constant of Salicylic 136. Mr. Juan Dela Cruz adds 125 mL of
Acid is 6.30x10(-5) at 25°C. Calculate the pka Strong Iodine Solution USP (7.5 % w/v) to a
value. liter of Sterile Water for Irrigation. What is the
a. 4.89 percent (w/v) of Iodine?
b.5.35 a. 0.90 %
c. 4.76 b. 0.83 %
d. 4.20 c. 0.94%
e. 4.30 d. 0.75%
e. 0.99%
132. What is the pH of a buffer solution
prepared with 0.5 M Sodium Benzoate and 137. How many proof gallons are contained in
0.05 M Benzoic Acid is 6.4x 10(-7) at 25°C? 10 wine gallons of a 75.0% (v/v) alcohol?
a. 12
b. 5
a. 8.56 c. 10
b. 7.19 d. 15
c. 10.24 e. 18
d. 9.26
e. 8.00 138. A prescription calls for 325 mg of Aspirin.
After weighing this amount, the pharmacist
133. How many mL of Hydrochloric Acid USP decided to check by weighing again. Now he
(37% w/w; sp. gr.= 1.8) are needed to prepare finds he has only 315 mg. What is the
150 mL of dilute Hydrochloric Acid (10.0% percentage?
w/v)? a. 3.10 %
a. 22.5 mL b. 3.11 %
b. 34.3 mL c. 3.06 %
c. 42.1 mL d. 3.08 %
d. 27.4 mL e. 3.00 %
e. 25.2 mL
139. What is the dose for A 38.5 lb child if the
average adult dose of a drug is 125 mg?
134. What is the HLB of a mixture of 30.0% of a. 3.21 mg
Tween80 and 70.0% of Span80? HLB of b. 32.1 mg
Span80=4.3; Tween 80=15.0 c. 0.32 mg
a. 7.5 d. 321.0 mg
b. 8.7 e. 30.21 mg
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a. 1.138
140. What is the dose for a ten-month old b. 8.31
baby if the average adult dose is 250 mg? c. 0.381
a. 16.55 mg d. 0.831
b. 12.12 mg e. 0.038
c. 18.77 mg
d. 16.67 mg 146. Franco Ravales has been instructed to
e. 17. 11 mg take 15 mL of Cloxacillin oral suspension
every other hour for four doses daily. How
141. A Tetracycline Syrup is preserved with many days will two 12-fluidounce bottles of
0.08% (w/v) of methylparaben 0.02% (w/v) of the suspension last?
Propylparaben and 0.10 %(w/v) of Sodium a. 12 days
Metabisultfite. Express these concentrations b. 13 days
in ratio strengths. c. 10 days
a. 1:1000, 1: 5000, 1:1250 d. 15 days
b. 1:1250, 1:5000, 1:1000 e. 14 days
c. 1:5000, 1: 2000, 1: 2500
d. 1: 1250, 1: 5000, 1: 1250 147. Baby De la Vega weighing 25 lbs. is to
e. 1: 1750, 1: 1000, 1: 1500 receive 4 mg of Phenytoin per kg body weight
daily as an anticonvulsant, How many
142. If 198g of sodium chloride are dissolved pediatric phenytoin suspension should
in 1000 mL of water, what is the % strength containing 30 mg /5 mL should the child
(w/w) of the solution? receive?
a.16.5 % a. 7.6 mL
b. 11.5 % b. 6.6 mL
c. 15.6 % c. 5.6 mL
d. 15.5 % d. 1.6 mL
e. 6.5% e. 8.6 mL

143. If 120 g of Chloroform measures 150 mL, 148. How many grams of white wax shoukld
what is its specific volume? be added to 250g of a 25% Zinc Oxide
a. 2.25 Ointment to make 5% ointment?
b. 1.50 a. 100 g
c. 1.25 b. 500 g
d. 0.95 c. 1000 g
e. 1.5 d. 1250 g
e. 10000g
144. Five pints of Benzene weighs 2. 79 kg.
Compute its specific gravity. 149. An intravenous solution containing 100
a. 3.180 mg of a drug substance in each 250 mL is to
b. 2.180 be administered at the rate of 150 mcg of drug
c. 1. 180 per minute. How many mL of the solution
d. 0.180 would have been given in an hour?
e. 2.020 a. 2.25 mL
b. 6.0 mL
145. A glass plummet weighs 16.60 in the air, c. 3.75 mL
13.65 when immersed in water and 11.20 g d. 9.10 ml
when immersed in mineral oil. What is the e. 3.25 mL
specific gravity of mineral oil?
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150. A vial of tobramycin sulfate contains 100 d. 3.45

mg of drug in 2 mL of injection, how many e. 4.7
milliliters of the injection should be
administered to obtain? 155. A liniment contains 12% (v/v) of methyl
a. 0.006 mL salicylate. How many milliliters of the liniment
b. 0.04 mL can be made from two pints of methyl
c. 0. 03 mL salicylate?
d. 0.004 mL a. 140.50 mL
e. 4.0 mL b. 170. 28 mL
c. 65.08 mL
151. A drug substance has been shown to be d. 189.21 mL
embryotoxic in rats at the dose of 30 e. 200.00 mL
mg/kg/day. Express the dose on the basis of
mcg/lb/day. 156. Express three mg of active ingredients in
a. 13620 two mL of solutions as ratio strength.
b.8760 a. 1:667
c. 11245 b. 1:458
d. 14900 c. 1:920
e. 14325 d. 1:700
e. 1:554
152. If one fluid dram of a cough syrup
contains 15 grains of sodium citarate, how 157. What is the % concentration of
many milligrams are contained in 5 mL? cholesterol in a patient's blood serum if the
a. 320 mg cholesterol level is determined to be 280 mg
b. 1025 mg %?
c.972 mg a. 0.43%
d. 675 mg b. 0.65%
e. 873 mg c. 0.28%
d. 0.51%
153. A physician advises an adult patient to e. 0.34%
take a children's aspirin tablet (81 mg of
aspirin per tab) daily as a precaution against 158. How many mL of 1:300 (w/v) stocks
heart attack,. Instead, the patient decides to solution should be used to make five liters of a
cut 5-grain aspirin tablet into dosage units. 1:2000 (w/v) solution?
How many doses could be obtained from each a. 758
5-grain tablet? b. 890
a. 4 c. 623
b.6 d. 920
c. 8 e. 854
d. 10
e. 7 159. A topical solution contains 35% (w/w) of
erythromycin. Express the concentration of
154. Two (2) lbs of a fungicidal ointment erythromycin in terms of milligrams per
contains 12.00 g of undecylenic acid. milliliter (mg/mL).
Calculate the percentage (w/w) of the a. 225
undecylenic acid in the ointment. b. 500
a. 6.8 c. 350
b. 2.0 d. 400
c. 1.32 e. 375
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d. 1.95
160. Hepatitis B Virus Vaccine Inactivated is e. 76
inactivated with 1:4000 (w/v) of formalin.
Express this as percentage strength. 165. How many milliliters of an injection
a. 0.25 containing 25 mg of gentamicin in each 2 mL
b. 0.025 should be used in filling a medication order
c. 0.04 calling for 3.5 mg gentamicin to be
d. 0.004 administered intramuscularly?
e. 0.4 a. 0.40
b. 0.50
161. The usual IM dose of kanamycin sulfate c. 0.28
is the equivalent of 7.5 mg kanamycin per kg d. 0.65
of body weight. How many milliliters of e.0. 34
kanamycin sulfate injection containing the
equivalent of 250 mg kanamycin per mL 166. If a dosage table for prefabricated drug
should be given to a person weighing 170 lb? product indicates the dose for a patient
a. 4.1 weighing 120 pounds to be 0.5 mg/kg of body
b. 0.9 weight, taken three times a day for 10 days,
c. 2.3 how many 20-mg tablets of the product
d. 3.4 should be dispensed?
e. 3.6 a. 41.25
b. 5.25
162. The adult dose of a liquid medication is c. 0.28
0.15 mL per kg of body weight to be d. 48.85
administered as a single dose. How many e. 39.65
teaspoonfuls should be administered to a
person weighing 225 lb? 167. If two pints of guaifenasin elixir is present
a. 3 in the inventory, how many 4-fluid ounce
b. 5 prescription can be filled?
c. 2 a. 6
d. 1 b. 8
e. 4 c. 10
d. 4
163. How many grams of fluorouracil will a e. 12
160-lb patient receive in six (6) successive
days at a dosage rate of 12 mg/kg/day? 168. If Efudex cream contains 5% fluorouracil,
a. 5.24 calculate the percentage (w/w) of fluorouracil
b. 6.10 in the prescription?
c. 2.35 Fluorouracil 20g
d. 1.95 Efudex cream 60 g
e. 5.45 White Petrolatum ad 300g
Sig. Apply as directed
164. The loading dose of chloramphenicol in a. 7.67%
neonates is 20 mg/kg of body weight. If b. 9.20%
neonates weighed 7 lbs, what is the loading c. 10.20%
dose? d. 5.56%
a. 73 e. 6.58%
b. 64
c. 2.35
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169. A pediatric product is formulated to a. 550, 200 U

contain 150 mg of erythromycin ethylsuccinate b. 326, 000 U
in each dropperful (2.5 mL) of the product. c. 600, 300 U
How many grams of erythromycin d. 417,000 U
ethylsuccinate would be required to prepare e. 250,000 U
400 bottles each containing 50 mL of the
preparation? 174. If 10 mcg of ergocalciferol represents
a.750 g 500 units of vitamin D, how many 1.25-mg
b. 1150 g ergocalciferol capsules will provide a dose of
c. 1000 g 300,000 units vit D
d. 1200 g a. 3.2
e. 675 g b. 5.9
c. 6.7
170. A nasal inhaler contains 200 mg of d. 4.8
propylhexedrine and 12.0 mg of menthol. How e. 7.2
many g of propylhexedrine would be used in
preparing 200 inhalers?; 175. In what proportion should 10% and 2%
a.300 coal tar ointment be mixed to prepare 5%
b. 400 ointment?
c. 600 a. 3:5
d. 800 b. 4:5
e. 500 c. 5:2
d. 2:6
171. In what proportion should 95% alcohol e. 3:4
mixed with 30% alcohol to make 70 %
alcohol? 176. Using a vial containing 200,000 units of
a. 40 :25 penicillin G potassium , how many milliliters of
b. 25: 40 solvent should be added to the dry powder in
c. 30: 45 preparing in a solution having a concentration
d. 45:30 of 10,000 units per mL?
e. 15: 35 a.15
b. 38
c. 20
172. Corticotropin injection is available in a d. 32
concentration of 40 units per mL. How many e. 25
mL of the injection should be administered to
provide 0.5 unit per kg for a child weighing 70 177. A disinfectant concentrate for surgical
lbs. instruments contains 8% (w/v) of a quaternary
a. 0.4 mL ammonium compound. What is the
b. 2.5 mL percentage strength of a solution resulting
c. 0.8 mL from the addition of 60 mL of the concentrate
d. 1.1 mL to 2 liters of water?
e. 0.6 mL a. 0.02%
b. 0.5%
173. A physician prescribes 60 mL of c. 0.35%
phenoxymethyl penicillin for oral suspension d. 0.1%
containing 5,000,000 units. How many e. 0.25%
penicillin units will be represented in each
teaspoonful dose of the prepared suspension?
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178. A physician advises an adult patient to c. 12.6 gr

take Amoxicillin Oral Suspension (250 mg/ 5 d. 14.6 gr
mL) in doses of 2 teaspoonfuls 4x a day for 4 e. 13. 6 gr
days, and then 1 teaspoonful 4x a day for 2
days . How many milliliters of suspension 183. How many gallons of 20% (v/v) would be
should be dispensed to provide the quantity equivalent to 30 proof gallons?
for the prescribed dosage regimen? a. 50 gallons
a. 250 mL b. 65 gallons
b. 300 mL c. 75 gallons
c. 150 mL d. 60 gallons
d. 200 mL e. 70 gallons
e. 275 mL
184. If 15 g of sodium borate are dissolved in
179. A pediatrician prescribed 25 mg Ascorbic 100 mL of water, what is the percentage
acid to be given orally to Baby Cruz twice a strength (w/w) of the solution?
day. How many milliliters of Ascorbic acid a. 1.5%
drops containing 46 grains/ 15 mL container b.15.0%
should be used to provide for this dose? c. 3.0%
a. 0.25 mL d. 13.0 %
b. 0.40 mL e. 1.3%
c. 0.35 mL
d. 0. 45 mL 185. If a syrup containing 65% (w/v) of sugar
e. 0.50 mL is evaporated to 85% of its volume, what
percent (w/v) of sugar will it contain?
180. A physician ordered an iso-alcoholic elixir a. 90%
containing 40% alcohol, to be prepared from b. 85%
low alcoholic elixir (10% alcohol) and high c. 80%
alcoholic elixir (78% alcohol). How many fluid d. 76%
ounces of low alcoholic elixir is needed to e. 72%
prepare 5 liters of iso-alcoholic extract.
a. 90.40 186. How many mL of a 1:400 (w/v) stock
b. 74.60 solution should e used to make 5 liters of a
c. 94. 50 1:2000 (w/v) solution?
d. 78.70 a. 750 mL
e. 94.60 b. 800 mL
c. 1000 mL
181. If the dose Diazepam is 150 ug , how d. 1250 mL
many doses are contained in 0.120 g? e. 1125 mL
a. 500 doses
b. 750 doses 187. A topical cream contains 0.2% (w/w) of
c. 900 doses Nitrofurazone. How many grams of
d. 800 doses Nitrofurazone are there in one pound of the
e, 850 doses cream?
182. If 1000 mL of an IV fluid contains 2g of a. 2.0 g
an added antibiotics, how many grains of the b. 0.91 g
antibiotic were administered to a patient who c. 0.82 g
received 1 pint of the fluid? d. 0.2 g
a. 10.6 gr e. 1.0 g
b. 11.6 gr
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188. Hepatitis B virus vaccine inactivated is 193. A bottle of Aspirin tablets is sold for
inactivated with 1:5000 (w/v) of formalin. P230.00, thereby yielding a gross profit of
Express this ratio strength in percentage 25% on the cost. What was the cost of the
strength. bottle of Aspirin tablets?
a. 2.0% a. P150.00
b.0.2% b. P196.00
c. 0.02% c. P184.00
d. 0.002% d. P172.00
e. 20.0 % e. P190.00
189. How many mL of a 1:5000 solution of
phenol can be made from 125 mL of a 0.5% 194. What should the percentage markup on
(w/v) solution? the cost of an item to be to yield a 22.75%
a. 3125 mL gross profit on the selling price?
b. 5 mL a. 28.75%
c. 80 mL b. 31.55 %
d. 1050 mL c. 32. 25%
e. 500 mL d. 29.45%
e. 28.60%
190. A solution contains 500 mg of Amoxicillin
per 120 mL and has a dose of 10 drops .If the 195. The list price of Diphenhydramine syrup
dispensing dropper calibrates 20 drops/mL, is P450.00, less 15% .What is the net cost of
how many mg of Amoxicillin are contained in the syrup?
each dose? a. P382.50
a. 2.1 mg b. P377.25
b. 2.2 mg c. P365.00
c. 2.75 mg d. P390. 00
d. 2.0 mg e. P 372.00
e. 2.4 mg
196. If 2 fluidounces of glycerin weigh 1140
191. If the cost of 100 tablets of Paracetamolis grains , what is its specific gravity?
P270.00 and the pharmacist applies a 33 1/3 a. 1.252
% mark up on cost, what would be the selling b. 1.327
price? c. 1.227
a. P150.00 d.1.229
b. P196.00 e. 1.427
c. P184.00
d. P172.00 198. If 250 units of an antibiotic weigh 1 mg,
e. P190.00 how many units are in 25 mg?

192. The cost of 100 tablets of Maalox Plus is a. 6258

P360.00. What should be the selling price per b. 6255
hundred tablets to yield a 40% gross profit on c. 6250
the selling price? d. 6350
a.P 540.00 e. 6245
b. P600.00
c. P720.00 199. What is the the dose of a drug for a child
d. P480.00 who weighs 28 lbs. if the average adult dose
e. P500.00 is 100 mg?
a. 18.6 mg
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PHARMACEUTICAL CALCULATIONS

b. 17.6 mg 205. How many milligrams of

c. 18.8 mg brompheniramine maleate would be contained
d. 17.8 mg in a 120- milliliter bottle, if a cough preparation
e. 18.2 mg contains 5 milligrams of the same ingredient in
each 5 millimeter dose?
200. What is the dose of drug for a 6-year old a. 12
child if the average adult dose is 100 mg? b. 120
a. 1/2 g c. 1.2
b. 1/2 gr d. 60
c. 1/2 mg e. 0.12
d. 1/2 ug
e. 1 gr 206. How much will the company pay for 3
and a half gallons of certain liquid preparation
201. If 325 pounds of a chemical cost PhP if 25 gallons of it cost PhP 14, 575?
525, what will be the cost 125 pounds? a. PhP 20,000.00
a. PhP 202 b. PhP 2,400.50
b. PhP 300 c. PhP 2004.50
c. PhP 221 d. PhP 2040. 50
d. PhP 312 e. PhP2450.00
e. PhP 225
207. How many grams of coloring reagent A
202. A drug formula for 750 capsules contains will a pharmaceutical fir, purchase if it intends
5.75 grams diazepam. How many grams of to make 150 gallons of syrup using the
diazepam should be used in preparing 475 formula that indicates that 75 gallons of syrup
capsules? contains 15 grams of coloring reagent A?
a. 2.52 a.50
b. 3.01 b.100
c. 3.75 c.65
d. 4.02 d. 150
e. 3.64 e. 5

203. If 100 tablets contain a total 25 grams of 208. If 50 tablets claims to contain 2.5 grams
paracetamol, how many tablets can be formed of an active ingredient, how much will 725
from 126 grams of paracetamol? tablets contain?
a. 525 a. 38.50 g
b.603 b. 37.25 g
c. 500 c. 36.00 g
d. 504 d. 36.25 g
e. 595 e. 39.00 g

204. If 40 kilograms of Green Soap was 209. A metered dose inhaler, which is
bought at PhP 2550, how much will 15 kg sufficient for 200 inhalations contains 125
cost? milligrams of metaproterenol sulfate, How
a. PhP 952.65 many milligrams of active ingredient would be
b. PhP 925.56 administered in each inhalation?
c. PhP 926.65 a. 0.825
d. PhP 956.25 b. 0.750
e. PhP 965.25 c. 0.600
d.0.625
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e. 0.525 a. 750
b. 75
210. How many minims would provide 20 c. 0.75
grains of ipecac if the available ipecac syrup d. 7.5
claims to contain 42 grains? e. 0.075
a. 0.476
b. 3.81 215. If an injectable solution contains 40 ug of
c. 480.25 a drug substance in each mL, how many
d.60.00 millilitres will be required to provide 0.25 mg of
e.228.57 the substance?
a. 5
211. A multivitamin preparation contains 1000 b. 4.5
units of Vitamin A per milliliter of solution. How c. 6.25
many units of vitamin A would be d. 6
administered to a patient given 3 drops of the e. 5.75
solution from a dropper calibrated to deliver
25 drops per millilitre of solution? 216. If a cough syrup contains 5 mg of
a. 240 U brompheniramine maleate in each 10 mL, how
b.120 U many milliliters of the agent will be contained
c. 100 U in a 250 mL container of the syrup?
d. 25 U a. 500 mL
e.125 U b. 125 mL
c, 0.2 mL
212. How many units of penicillin will 0.75 d. 250 mL
milliliters contain if it is from a prepared e. 100 mL
solution containing 5 million units of penicillin
per 5 milliliters? 217. If a potassium elixir contains 45 mEq of
a. 125,000 U potassium ion in each 15 mL of elixir, how
b. 200,000 U many milliliters will provide 30 mEq of
c. 1,000,000 U potassium ion?
d. 750,000 U a. 10 mL
e. 800,000 U b. 15 mL
c. 20 mL
213. A drug preparation contains the d. 30 mL
equivalent of 0.5 milligram of fluoride ion in e. 90 mL
each millilitre. How many milligrams of fluoride
ions would be provided by a dropper which 218. If a syringe contains 15 mg of medication
delivers 0.8 mL? in each 20 mL of solution, how many
a. 0.4 milligrams of medication would be
b. 4 administered when 8 mL of solution are
c. 40 injected?
d. 0.04 a. 11 mg
e. 0.004 b. 10 mg.
c. 6 mg
214. An inhalational aerosol contains 450 mg d. 8 mg
of metaproterenol sulphate which is sufficient e. 12 mg
for 600 inhalations. How many micrograms of
metaproterenol sulphate would be contained
in each inhalation?
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219. How many grams of dextrose are 224. How many grams of a chemical will
required to prepare 4,000 mL of a 5% w/v remain in a 2.0 oz bottle after 15 grams are
solution? removed?
a. 2000g a. 824 grams
b. 8 g b. 836 grams
c. 200 g c. 857 grams
d.125 g d. 875 grams
e. 20 g e. 860 grams

220. A medication order calls for 1000 mL of a 225. If a drug costs P 125.00 per ounce, what
dextrose intravenous infusion to be is the cost of 120 grains?
administered over a 12 hr. Period. Using an a. PhP 34.50
intravenous administration set that delivers 10 b. PhP 34.00
drops/mL, how many drops per minute should c. PhP 34.75
be delivered to the patient? d. PhP 34.80
a. 12 e. PhP 34.30
b.11
c. 15 226. A formula of cough syrup contains 1/8
d. 14 grains of codeine phosphate per teaspoonsul
e. 9 (5 mL). How many grams of codeine
phosphate should be used in preparing 1 pint
221. The usual dose of chlorambucil is 150 of the cough syrup?
ug/kg of body weight per day. How many a. 0.0769 g
milligrams should be administered to a patient b. 0. 759 g
weighing 122 lbs.? c. 0. 769 g
a. 10.5 d. 7. 590 g
b. 11.2 e. 0.0759 g
c. 6.25
d. 7.74 227. A drug substance has been shown to be
e. 8.32 embryotoxic in rats at doses of 50 mg/kg/day.
Express the dose on the basis of micrograms
222. If a low-strength aspirin tablet contains per pound per day.
81 mg of aspirin per tablet, how many tablets a. 22727.27 ug/lb/day
may be prepared from 0.5 kg of aspirin? b. 22772.27 ug/lb/day
a. 6272 c. 21727.77 ug/lb/day
b. 6 d. 21722.77 ug/lb/day
c. 6172 e. 22227.72 ug/lb/day
d. 6000
e. 65 228. Tetracycline has been shown to form
calcium complex in bone-forming tissue in
223. How many fluid-ounce bottle may be infants given oral tetracycline in doses of
filled from 5 gallons of cough syrup? 0.011g/lb of body weight every 6 hrs. Express
a. 310 bottles the dose in terms of milligram per kg of bosy
b. 320 bottles weight.
c. 315 bottles a. 23.4 mg/kg
d. 225 bottles b. 24.2 mg/kg
e. 300 bottles c. 24.3 mg/kg
d. 243.0 mg/kg
e. 242.0 mg/kg
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obtain the required amount of

229. The dimensions of nicotine transdermal chlorpheniramine maleate with an error not
patch system are 4.7 cm by 4.8 cm. Express greater than 4%.
these dimensions in corresponding inches,. a. Weigh ½ of dilution, or 50 mg, which
a. 1.85 in x 1.89 in contains 25 mg of chlorpheniramine maleate
b. 1.84 in x 1.87 in b. Weigh ½ of dilution, or 100 mg, which
c. 1.84 in x 1.89 in contains 50 mg of chlorpheniramine maleate
d. 1. 84 in x 1.85 in c. Weigh ½ of dilution, or 50 mg, which
e. 1.85 in x 1.87 in contains 50 mg of chlorpheniramine maleate
d. Weigh ½ of dilution, or 100 mg, which
230. A pharmacist attempted to weigh 120 mg contains 25 mg of chlorpheniramine maleate
of codeine sulphate on a balance beam with a e. Weigh ½ of dilution, or 150 mg, which
sensitivity requirement of 6 mg. Calculate the contains 50 mg of chlorpheniramine maleate
maximum potential error in terms of
percentage. 234. A prescription calls for 0.2 mL of clove
a. 4.5 % oil. Using a 25-mL graduated vessel calibrated
b. 4.0 % in units of 5.0 mL, how much would you obtain
c. 5.2 % the required amount of clove oil using the
d. 2.5 % aliquot method and alcohol as diluents?
e. 5.0 % a. Weigh 1/5 of dilution, or 2 mL, which
contains 0.2 mL of clove oil
231. Using a graduated cylinder, a pharmacist b. Weigh 1/20 of dilution, or 2 mL, which
measured 30 mL of a liquid. On subsequent contains 0.2 mL of clove oil
examination, using a narrow-gauge burette, it c. Weigh 1/10 of dilution, or 4 mL, which
was determined that the pharmacist had contains 0.2 mL of clove oil
actually measured 32 mL. What was the d. Weigh 1/10 of dilution, or 2 mL, which
percentage of error in the original contains 0.2 mL of clove oil
measurement? e. Weigh 1/5 of dilution, or 2 mL, which
a.6.7% contains 0.4 mL of clove oil
b. 7.0%
c, 5.2% 235. A pharmaceutical formula calls for 0.4
d. 6.5 % mL of the surfactant polysorbate 80. Using
e. 5.9% water as the diluent and a 25 mL graduated
vessel calibrated in 1 mL units, how could you
232. A torsion prescription balance has a obtain the desired quantity of polysorbate 80
sensitivity requirement of 6.5 mg. How would by the aliquot method using water as the
15 mg of a drug be weighed with an accuracy diluents?
of 5%, using aliquot method and lactose as a. Measure 1/10 of the dilution, or 4 mL, which
the diluent? contains 0.4 mL of polysorbate 80
a. 132 mg b. Measure 1/10 of the dilution, or 2 mL, which
b. 131 mg contains 0.5 mL of polysorbate 80
c. 130 mg c. Measure 1/5 of the dilution, or 2 mL, which
d. 131.5 mg contains 0.4 mL of polysorbate 80
e. 129 mg d. Measure 1/10 of the dilution, or 2 mL, which
contains 0.4 mL of polysorbate 80
233. A prescription calls for 50 mg of e. Measure 1/10 of the dilution, or 5 mL, which
chlorpheniramine maleate. Using a contains 0.4 mL of polysorbate 80
prescription balance with a sensitivity
requirement of 4 mg, explain how you would
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236. The biotechnology-derived product d. 0.0035% w/v

Neupogen contains 300 ug of filgrastin in the e. 0.30% w/v
product.
a. 0.04% 241. How many liters of a 2% w/v iodine
b. 0.40% tincture can be made from 123 g of iodine?
c. 0.03% a. 6.20 L
d. 0.35% b. 6.15 L
e. 0.30% c. 6.25 L
d. 6.22 L
237. If an injection contains 0.5% w/v of e. 6.18 L
diltiazem HCl, calculate the number of
milligrams of the drug product in 25 mL of 242. A biotechnology-derived product contains
injection. 300 ug of filgrastim in each millilitre of
a. 125.0 mg injection. Calculate the concentration of
b. 124.5 mg filgrastim in the product.
c. 125.5 mg a.0.03%
d. 123.0 mg b. 0.05%
e. 124.0 mg c. 3%
d. 3.5%
238. How many grams of potassium e. 3.2%
permanganate should be used in
compounding the following prescription? 243. If an injection contains 0.5% w/v of
Rx Potassium permanganate 0.02% diltiazem hydrochloride, calculate the number
Purified Water ad 250 mL of milligrams of the drug in 25 mL of injection.
a. 0.04% w/v a. 125 g
b. 0.40% w/v b. 12.5 mg
c. 0.03% w/v c. 125 mg
d. 0.35% w/v d. 1.25 mg
e. 0.30% w/v e. 12.5 g

239. A pharmacist adds 10 mL of a 20% w/v 244. How many grams of Potassium
solution of potassium iodise to 500 mL of permanganate should be used in
D5W for parenteral infusion. What is the compounding the following prescription?
percentage strength of potassium iodide in the Rx
infusion solution. Potassium Permanganate 0.02% w/v
a. 0.49% w/v Purified water ad 250 mL
b. 0.40% w/v a. 0.005 g
c. 0.03% w/v b. 0.05 g
d. 0.39% w/v c. 0.05 g
e. 0.30% w/v d. 50.0g
e. 5.0 g
240. Rx Allopurinol 200 ug tablets 12 tablets
Lidocaine HCl 1g 245. A pharmacist adds 10 mL of a 20% w/v
Glycerine qs ad 100 mL solution of potassium iodide to 500 mL of
Calculate the percent strength of allopurinol in D5W for parenteral infusion. What is the
the prescription. percentage strength of the potassium iodide in
a. 0.0043% w/v the infusion solution?
b. 0.0024% w/v a.3.9%
c. 0.0365% w/v b. 39%
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c. 4.0% suppositories each weighing 2 g and

d. 0.0039% containing ¼ % of procaine hydrochloride?
e. 0.39% a. 600 mg
b. 725 mg
246. Rx c. 500 mg
Misoprostol 200 ug tablets 12 tablets d. 635 mg
Lidocaine HCl 1g e. 435 mg
Glycerin qs ad 100 mL
Calculate the percent strength of misoprostol 251. One kilogram is equivalent to:
in the prescription. a. 1000 mg
a. 0.0024% b. 2.4 lb
b. 24.0% c. 1000 g
c. 0.024% d. 15.432 g
d. 2.4%
e. 0.24% 252. Mr. Lao is to receive a 260 mcg of drug 4
times a day for 14 days. How many 1/250
247. How many liters of a 2% w/v iodine grain tablets must be dispensed?
tincture can be made from 123 g of iodine? a. 58
a. 6.15 L b. 66
b. 32.5 mL c. 46
c. 3.25 L d. 56
d. 61.5 L
e. 6.15 mL 253. 2332 is equivalent to :
a. MCCCXXXII
248. Rx b. MMCCCXXXII
Gentamicin (40 mg/mL) injection 2mL c. MCMCCXXXII
Gentamicin(0.3%) ophth. Sol’n 5mL d. MMCCXXXII
Calculate the percent concentration of
gentamicin in this fortified ophthalmic solution. 254. The standard temperature for specific
a. 13.6% gravity determination based on USP
b. 22.4% requirement (except in alcohol) is:
c. 1.36% a. 20˚C
d. 16.36% b. 15.56˚C
e. 0.136% c. 4˚C
d. 25˚ C
249. How many milliliters of liquefied phenol
should be used in compounding the following 255. A cough syrup is labeled as containing
prescription? 20% alcohol by volume,. Which of the
Rx Liquefied phenol 2.5% following statement are true?
Calamine lotion ad 240 mL a. The proof strength of this product is 40
a. 5.4 mL b. each 100 mL of syrup contains exactly 20
b. 6 mL mL alcohol USP
c. 5.4 L c. each 100 mL of syrup contains exactly 40%
d. 4.2 L alcohol, USP
e. 54 mL d. None of these

250. How many milligrams of procaine 256. The body surface area can be
hydrochloride should be used in preparing 120 determined by using a chart called:
a. nomogram
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b. hologram total of 12,600 mg of aspirin, how many days

c. nanogram has he been taking this medication?
d. monogram a. 2 weeks
b. 21 days
257. Lomotil is a drug used to treat patients c. 12 days
suffering from diarrhea. In a certain study, 5% d. 2 ½ weeks
of 300 people showed no positive results
while being treated with lomotil. How many
people did not show positive results? 263. A child with a body surface area of 1.07
a. 150 m2 is to be given 2.5 mg of Valium® for every
b. 10 m2 of body surface. How many mg of Valium
c. 5 should be administered?
d. 15 a. 2675
b. 2
258. It is frequently used to measure or c. 4.04
evaluate alcohols of given quantities and d. 2.675
strengths:
a. proof spirit 264. Cimetidine is a drug that can produce
b. proof gallon side effects such as dizziness and a rash. The
c. wine gallon number of people who experience these side
d. proof strength effects is about 1% of all thise who take the
drug. If 1500 people take cimetidine, how
259. A solution with a concentration of 1:400 many persons are expected to experience the
is the same as: side effects?
a. 0.25% a. 150
b. 0.05% b. 15
c. 4% c. 1.5
d. ½% d. 100

260. What is the weight of 0.06L of oil whose 265. Dr. A. Cruz orders aminophylline
density is 0.9624 g/mL? suppositories, gr. Viiss stat and non rep. How
a. 5.770 g much drug should each suppository contain?
b. 57.74 g a. 7 grains
c. 6.0 g b. 7 ½ grains
d. 0.557 g c. 7 grams
d. 7 ½ grams
261.. Last November 13, 2004 , Dra. Nunez
delivered triplets at Delgado Memorial 266. Dra. J. Villapana orders
Hospital. The babies weighed 2 kg, and 3.01 Diphenhydramine 50 mg. How many capsules
kg. What was the sum weight of the triplets in should be given if the dose on hand is 0.025 g
kilogram? in each capsules?
a. 7.11 a. do not dispense
b. 7110 b. 1 ½
c.2105 c. 1
d.711 d. 2

262. Prof. Julienn Constantino has been 267. A prescription calls for a dose of 3 tsp of
taking 0.6 g of aspirin daily. If he has taken a medicine to be administered qid, 15 minutes
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before meals and at bedtime. How many days a. mg %

will a 350 mL bottle of the medicine last? b. parts per million
a. It will last for 6 days c. range
b. It will last for 6 days but there is not enough d. mg/mL
for 7 days
c. It will last for 5 days, but there is not enough 274. Concentrations of weak solutions are
for 6 days usually expressed in terms of:
d. It will last for 7 days, but there is not a. percentage strength
enough for 8 days b. units
c. Mcg
268. The potency of these compounds is d. ratio strength
expressed based on their activity, except:
a. antibiotics 275. 0.03 milligrans equals how many grams?
b. endocrine products a. 0.000003 g
c.electrolytes b. 30 g
d. biological c. 0.00003 g
d. 0.03 g
269. Willem receives daily medication doses
of 0.5 mg at breakfast, 0.5 mg & 0.25 mg at 276. How much of a substance is needed to
lunch, and 0.75 mg at dinner. How many prepare 1000 mL of a 1:10, 000 solution?
grams does Willemm consume each day? a. 0.1 g
a. 2 b. 10 g
b. 0.002 c. 0.01 g
c. 1.75 d. 1 g
d. 0.000175
277. Mr. Estrada, a patient with glaucoma
270. Triturations are dilutions of potent asked your help in interpreting the signs in his
medicinal substances with a concentration of: prescription “Timolol 0.25% 1 gtt, BID OU.”
a. 100% You will tell him to place 1 drop in:
b. 1:100 a. both eyes
c. 1:1 b. left eye
d. 1:10 c. right eye
d. both ears
271. Concentration expressed in ppm means:
a. parts per mole 278. The ratio 1: 5000 when expressed in
b. parts per milligram percentage strength is:
c.parts per million a. 0.0002%
d. parts per millilitre b. 2 %
c. 0.02%
272. It is used in solving problems that involve d. 0.2%
mixing solutions of different percentage
preparations: 279. A patient is to receive 0.26 mg of a drug
a. allegations 4 times a day for 14 days. Hoe many 1 /250
b. triturations grain tablets must be dispensed?
c. dilutions a.58
d. allegations b. 66
c. 46
273. Quanitity of trace impurities in chemical d. 56
samples is expressed in terms of
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280. The quanitity or amount administered to d. 44.4

or taken by the patient for the intended
medicinal effect: 287. A dose of 10 mg is prescribed for your
a. dosage regimen patient. You have the medication with a dose
b. dosage form strength of 4 mg/mL. How much medication
c. dosage range should you give to your patient?
d. dose a. 0.00025
b. 2500
281. The pharmacist prepares a 200 mcg c. 2.5 mL
dose of the anti-hypertensive drug, Clonidine d. 25 mL
(Catapres®). If each tablet equals 0.1 mg, the
pharmacist should give the patient:
a. ½ tablet
b. 2 tablets 288. You are asked to give a dose of 200 mg.
c. 5 tablets The available capsules are labelled 40 mg.
d. 2 ½ tablets How many capsules should be dispensed?
a. 5 caps
282. How many milligrams are there in 3/8 b. 1 cap
grains? c. 8 caps
a. 24.38 d. 2 caps
b. 23
c. 23.38 289. The prescribed reference dose for
d. 24 Cefaclor (Ceclor®) is 40 mg/kg. If your patient
weighs 11 kg, what dose should you give?
283. The part of the prescription which directs a. 0.0436 g
the patient on what to do: b. 2000g
a. signa c. 3.63 mg
b. subscription d. 440 mg
c. inscription
d. superscription 290. A child weighs 36 lb. What is her weight
in kilograms?
284. A STAT order is considered: a. 16. 36
a. follow- up orders b. 79.2
b as required c. 0.06
c. emergency drug d. 7.92
d. emergency order
291. Cefixime (Zinnat®) is prescribed for a 6.3
285. The dispensing direction to the kg infant. The reference dose for Zinnat is 8
pharmacist is: mg/kg. You have Cefixime 100 mg/ 5 mL.
a. inscription Calculate the number of mL/dose for the
b. subscription infant.
c. superscription a. 5.6
d. transcription b. 2.54
c. 2.56
286. If mercury freezes at -40 centigrade, d. 6.5
What is its freezing point on Farenheit scale?
a. 40 292. How much atropine do you give a patient
b. -40 who weighs 144 kg if the order reads 0.3 mg
c. 4.4 for every 100 lbs?
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a. 8.3 mg tablets in stock. How many tablets should

b. 83 mg he receive?
c. 0.75 mg a. 0.5 tab
d. 7.5 mg b. 1 tab
c. 1.5 tab
293. You are to give penicillin 450, 000 U. The d. 2 tabs
bottle of penicillin is labelled 300, 000 U/mL.
How many mL will you dispense? 298. Dr. Gonzales prescribes Augmentin®
a. 0.8 mL 0.875 g po q 12h for Ms Y. Kurdi. You have
b. 1.5 mL Augmentin® 875 mg in stock. How many
c. 0.4 mL tablets shoud you dispense?
d. 2.5 mL

294. Jillian is a 8 yr old and weighs 67.5

lbs. The prescribed dose of erythromycin a. 0.5 tablet
stearate is 20 mg/kg per dose QID. You b. 1 tablets
have erythromycin stearate 200 mg/5 mL c. 2 tablets
in stock. Calculate the number of d. 3 tablets
teaspoons of erythromycin/ dose for
Jillian. 299. Arrange the ff decimal number in
a. 4 tsp/ dose descending order according to size (1) 3.33
b. ¾ tsp per dose (2) 3.0330 (3) 3.333 (4) 0.0033
c. 3 tsp/ dose a. 4,2,1,3
d. 1 tsp per dose b. 4,1,2,3
c. 1,3,4,2
295. JM, a 16- Yr old boy weighs 45 kg d. 1, 3,2,4
and is to receive an initial insulin dose for
hyperglycemia and ketonuria. The 300. An injection of 0.004 g of Valium® has
prescription reads “regular insulin 0.1 U/kg been prescribed for a patient suffering from
SQ QID”. How many units of regular muscle spasm. An ampule of Valium®
insulin will JM receive in each dose? labelled 5 mg/mL is in hand. How many mL
a. 9.8 U/dose will be injected?
b. 18 U/dose a. 0.8 mL
c. 45 U/dose b. 30 mL
d. 4.5 U/dose c. 0,2 mL
d. 1.25 mL
296. You have received the following
prescription: “DRUG X 150 mg PO BID”.
What does the prescription order mean?
a. Administer Drug X 150 mg by mouth
twice a day
b. Administer Drug X 150 mg by mouth
every other day
c. Administer Drug X 75 mg twice a day
d. Administer Drug X twice a day for a total
150 mg in a 24 hr period

297. The Physician precscribes Diltiazem

HCl 60 mg for Mr. Herras. You have 30 mg