Cytogenetics Practice Test 2 Pre-Finals

Total points 52/52

Good day guys! this is a practice test for Cytogenetics to test your knowledge for the
upcoming 

Pre-Finals  exam. Please be advised that this test may or may not reflect  on the 

Pre-Finals  exam. Also, this is not compulsory and it only serves as a brain exercise,
however, I am hopeful that this will help you remember the basic concepts on
Cytogenetics. Kindly answer as honest as possible. Good luck!

Email *

dsa@gmail.com

0 of 0 points

Name (Optional)

qwerry

Introduction to Chromosomal Genetic 42 of 42 points

Read the questions carefully and please answer as honestly as you can, good luck!
 Identify the chromosomal abnormality:
* 1/1

Terminal Deletion

Inversion

Trisomy

Triploid

Interstitial Deletion

  In DNA sequencing which nucleotide do the following colors stand for:  

*

Adenine Thymine Guanine Cytosine Score

black 1/1

green 1/1

red 1/1

blue 1/1
Identify the chromosomal abnormality: * 1/1

Inversion

Trisomy

Triploid

Terminal Deletion

Interstitial Deletion

Genome maps had previously been completed for the following *1/1
individuals
EXCEPT:

Yang Huanming

Dan Stoicescu

Alfred Sturtevant

Craig Venter
  Triploidy may be due to:  
* 1/1

usually a postmeiotic event: most likely due to failure of an early mitotic cleavage
division in the zygote.

the union of 2 haploid gametes.

the union of 2 diploid gametes.

the failure in gametogenesis of one of the meiotic divisions giving rise to a 2N

gamete.

Gain or loss of one or a few chromosomes is known as

* 1/1

diploidy

triploidy

euploidy

aneuploidy

  Exact multiples of the haploid set of chromosomes is known as:    

* 1/1

diploidy

euploidy

triploidy

aneuploidy

Partial Hydatidiform Mole, being a Triploidy, is a result of the following:

* 1/1

the fertilization of a diploid egg by a sperm

gametogenesis of one of the meiotic divisions giving rise to a 2N gamete

fertilization of a 2N gamete by a haploid gamete from the other parent

the fertilization of a haploid egg by two sperm

Any two humans chosen at random would have approximately this *1/1
nucleotide
differences

3 billion

3 thousand

3 million

3 hundred

This genetic variation arises from chemical tags that attach to DNA and *1/1
affect
how it gets read

nucleotide diversity

epigenetics

copy number variation

An individual with two cell lines that differ only by a single chromosome *1/1
is
called a:

Mosaic

Heterogenic

Genius

Aneuploid

  Liveborn autosomal trisonomies include the following chromosomes *1/1

EXCEPT:  

21

18

13

16
  It refers to the two breaks occuring on the same side of the centromere *1/1
(i.e. in
the same arm).   

paracentric

metacentric

pericentric

acrocentric

  Which statement is CORRECT about Composite & Personal *1/1

sequencing?  

Composite sequence is haploid, while personal sequence is diploid

Composite sequence is diploid, while personal sequence is haploid

Both Composite and personal sequences are haploid

Both Composite and personal sequences are diploid

Give the gender of this person: * 1/1

Male

Female

Cannot be determined

Other:

When copy number variation is included, human to human genetic *1/1

variation is
estimated to be at least:

5%

0.005%

0.05%

0.5%
  Give the groupings of the following Autosomes: (Choices may be used more *
than once)  

Group A Group B Group C Group D Group E Score

Chromosome
1/1
18

Chromosome
1/1
9

Chromosome
1/1
3

Chromosome
1/1
5

Chromosome
1/1
15

Structural Chromosomal Abnormalities: (Choices may be used more than

once)
*

Balanced Unbalanced Score

deletion 1/1

translocation 1/1

inversion 1/1

duplication 1/1

Only about ___of the genome codes for proteins

* 1/1

0.5%

1.5%

5%

3%
Which of the following statements is NOT CORRECT regarding *1/1
Aneuploidy?

More than one pair of chromosomes are usually involved

More common cause are the nondisjunctional errors resulting in aneuploidy.

Here, there is one extra chromosome or one missing chromosome per cell.

Nondisjunction errors may occur in either meiosis or mitosis.

  This method of detection identifies the landmarks of DNA.  

* 1/1

genome sequencing

genome mapping

  The only viable monosomy is    

* 1/1

(45,Y)

(45,X)

(46,Y)

(46,X)
Classify the Type of RESCUE MECHANISM applied in each case, to reinstate the *
chromosome pair.

Biparental uniparental uniparental Biparental

Score
heterodisomy isodisomy heterodisomy isodisomy

B 1/1

C 1/1

D 1/1

A 1/1

  7q31.2 indicates that the location is on:   

* 1/1

chromosome 2, arm 1, band 3, sub-band q, and sub-sub-band 7

sub-sub-band 7, sub-band 3, band 1, q arm, and chromosome 2

chromosome 7, q arm, band 31, sub-band 2

chromosome 7, q arm, band 3, sub-band 1, and sub-sub-band 2

Copy number variation results from the following EXCEPT: * 1/1

deletions,

duplications

SNPs

inversions,

The haploid human genome contains between _________human protein- *1/1

coding
genes.

20,000 - 21,000

20,000-25,000

23,000 – 28,000

17,000 -20,000

  A trisomy of this chromosome is the most commonly detected trisomy *1/1

in
spontaneous abortus tissue  

18

16

13

21
   Identify the chromosomal abnormality:   
* 1/1

Inversion

Terminal Deletion

Triploid

Interstitial Deletion

Trisomy

  The following statements are TRUE of Complete Mole:   

* 1/1

caused by a single sperm combining with an egg which has lost its DNA.

caused by two sperms combining with an egg which has lost its DNA.

caused by a single sperm combining with 2 eggs that have joined their DNA.

1st & 2nd choices only

2nd & 3rd choices only

All of the above

Introduction to Banding-Genetic variation 5 of 5 points

Read the questions carefully and please answer as honestly as you can, good luck!

R bands refer to the following:

* 1/1

previously positive G-bands

light G-band becomes darker band

pre-treating the chromosome in hot alkaline solution

it is the reverse pattern of the G-negative bands

1st 3 choices only

last 3 choices only

all of the above

This type of DNA sequencing studies the diploid, representing both sets *1/1
of chromosomes.

Mapping

Personal

Composite

Genetic variation among individual humans occurs on the following *1/1

 scales:

single nucleotide polymorphisms

copy number variation

Epigenetics

1st 2 choices only

All of the above

 The gene-rich regions in the chromosomes are usually located in this *1/1
area:

Adenine- Thymine areas

Cytosine-Guanine areas

Adenine-Uracil areas

3-hydrogen bonds areas

1st & 3rd choices ony

2nd & 4th choices only

All of the above

The vast majority of the human genome size codes for proteins.
* 1/1

FALSE

TRUE

IT DEPENDS ON THE CHROMOSOME NUMBER

Introduction to Chromosomes Abnormality Part 1 5 of 5 points

Read the questions carefully and please answer as honestly as you can, good luck!

The condition called "Partial hydatidiform mole" is an example of _____

* 1/1

Diploidy

Triploidy

Tetraploidy
 Rearrangements may be _______ , if all the chromosomal material is *1/1
present and functional but simply arranged in a different conformation.

balanced

unbalanced

Describe the following:

*

Exact multiples Gain or loss of

of the haploid set one or a few Score
of chromosomes chromosomes

euploidy 1/1

aneuploidy 1/1

The only liveborn monosomy is ____.

* 1/1

chromosome X

trisomy 21

Trisomy 16

tetraploid

This form was created inside of Liceo de Cagayan University.

 Forms