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We realized and discovered that doctors were thinking about filling, not collagen regeneration.

That's why the name is neither. When doctors started using New-fill, they thought it was a filler,
and it would produce enormous complications. That is why many European doctors still think that
New-fill induces nodules and brain clogs. This is not true. It is not a filler. It cannot be used as a
filler. So, in 2004, the FDA approved polylactic acid with a particular indication, Lipoatrophy. This is
very strange. It's a very typical phenomenon of HIV patients. They don't have AIDS. It's just HIV.
We don't know why this fat compartment is used. The first to publish about this were the French.
On the left is stage one, Lipoatrophy. On the right side, you have stage two. Here are stages three
and stage four. As you can see, there is this strange Lipoatrophy. We don't know why it occurred
since it only occurs in HIV patients. French doctors started injecting polylactic to recover the
volume. So obviously, the results were fantastic with a great percentage of improvement. What is
most interesting is that they mixed the product in about 4 to 5 mL. So that is why Bartek told you
I'm going to talk about reconstitution because I think it's fascinating how we reconstitute this
product completely differently today. This is what they found. They wanted to measure how much
volume they would be able to recover. The circles show what happened immediately after the
injection of New-fill. The triangles show New-fill injection after 12 weeks. It shows what happened
after 12 weeks. You can see a thickness recovery and a change of measurements from the
baseline. In the triangle, you can see what happened after twelve weeks. So, after 24 weeks or half
a year, we see that the volume induced is much higher than that injected immediately. This means
that we synthesize new collagen in 3, 4, 5, and 6 months. Ok? The product does not fill us. We
are making the filler. This is probably the first time in the history of aesthetic medicine that we
realize that it is not the product, filler, silicone, or whatever is filled in. It is something that we
produce. So it's natural, and it's about regenerating our skin. So obviously, this continued later,
and of course, the product was used in HIV patients. We can perfectly measure the improvement
of the thickness of the skin. Right? So this product was injected into the fat layer, 3 or 4 mm
deep. But this measurement tells us what's been changing in the skin's surface.

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