PHARMACEUTICAL CALCULATIONS B. 67.

2 units per 24 hours

C. 66.3 units per 24 hours
1. A 15-g tube of Triamcinolone acetonide 0.025% is D. 68.5 units per 24 hours
prescribed for one of your patients. How much E. 69.1 units per 24 hours
triamcinolone acetonide is present in the preparation?
A. 3.75 g 7. A capsule contains the following amounts of medicinal
B. 3.75 mg agents: 0.025 g, 15 mg, 0.0003 g, 2 mg, and 125 mg.
C. 3.5 g Determine the total weight of the medicinal agents in the
D. 0.375 g capsule.
E. 0.025 mg A. 167.3 g
B. 15.025 g
2. A prefilled syringe contains 2 mg of active drug in 5 ml C. 325 mg
of solution. How many micrograms of drug is D. 15.025 mg
administered by injecting 0.5 ml of the solution? E. 167.3 mg
A. 0.2 mcg
B. 400 mcg 8. A medication order indicates 1.5g of an antibiotic to be
C. 0.4 mcg added to 1000 ml of D5W. How many mL of a 250mg/3
D. 200 mcg mL injection should be added to the D5W to prepare this
E. 215 mcg medication order?
A. 12 mL
3. Determine the weight in grams of 3 fl oz of a liquid, B. 15 mL
with a specific gravity of 0.94. C. 18 mL
A. 83.39 g D. 20 mL
B. 95 g E. 22 mL
C. 9.4 g
D. 30 g 9. If the pediatric dose for an antibiotic is “7 mg/kg q 12
E. 15 g h”, what is the daily dose in mg for a child weighing 47
lb?
4. If the given dose for a given drug is 550 mcg per A. 299 mg per day
kilogram of the body weight, how many milligrams should B. 459 mg per day
be given to a patient weighing 60 lbs.? C. 377 mg per day
A. 15 mg D. 257 mg per day
B. 25 mg E. 302 mg per day
C. 20 mg
D. 10 mg 10. As a pharmacist what strength tablet and quantity
E. 30 mg would you recommend for an initial dose of 2000 mg of
divalproex sodium, if the drug comes in 250 ng and 500
5. Calculate the pediatric dose for a drug with an adult mg strength tablets?
dose of 120 mg for a child who is 5 years old, 40 inches A. Five 250 mg tablets, as initial dose
high, and weighs 35 lb. Use Young’s Rule. B. Four 500 mg tablets, as initial dose
A. 25.24 mg C. Two 1000 mg tablet as initial dose
B. 35.29 mg D. Two 500 mg tablets as initial dose
C. 27.13 mg E. Seven 250 mg tablets as initial dose
D. 28.15 mg
E. None of these 11. If a patient is found cut to have a serum cholesterol
level of 210 mg/dL, what is the equivalent express
6. A hospital medication order calls for isophane insulin in in mmol/L
suspension to be administered to a 145 lb patient on the A. 2.77 mmol/L
basis of 1 unit/kg per 24 hours. How many units of B. 5.43 mmol/L
isophane insulin suspension should be administered C. 210 mmo/L
safely for this patient? D. D. 5.21 mmol/L
A. 65.9 units per 24 hours E. 5.21 mmol/ L
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 17. Tafluprost ophthalmic solution contains 0.0015% w/v
12. Norgestrel and Ethynyl estradiol tablets are available active ingredient, available as 0.3 mL preservative-free
containing 0.5 mg on norgestrel and 50 mcg of ethynyl pouches intended for single use to be instilled into the
estradiol. How many grams of each ingredient would be affected eye. Calculate the number of single use pouches
used in making 50000 tablets? that could be made from 1 g of the drug.
A. 2.5 g Norgestrel; 2.5 g ethynyl estradiol A. 222222 pouches
B. 30 g norgestrel; 9.5 ethynyl estradiol B. 500000 pouches
C. 25 g norgestrel; 2.5 ethynyl estradiol C. 150870 pouches
D. 55 g norgestrel; 205 g ethynyl estradiol D. 2500 pouches
E. 25 g norgestrel; 3.5g ethynyl estradiol E. 224558 pouches

13. If a quart of liquid weighs 805 g, determine the 18. Rimantadine HCl is available as a 50 mg/ 5 mL syrup. If
liquid’s specific gravity. the recommended dose is 100 mg POBID x 5 days, how
A. 0.17 many mL should be dispensed to complete the therapy?
B. 0.85 A. 50 mL
C. 0.95 B. 100 mL
D. 0.57 C. 150 mL
E. 0.63 D. 200 mL
E. 250 mL
14. Express 1:4000 as percent strength
A. 0.25% 19. A patient being treated with Interferon alfa 2b for
B. 2.5% malignant melanoma is on a maintenance dose of
C. 0.025% 10,000,000 units/m2 SC 3 times per week for 48 weeks. If
D. 25% this is supplied as multidose pen, with 6 doses
E. 0.0025% each, which of the following should be used by the
patient with BSA 2.08 m2
15. Convert 32oC to Fahrenheit 22.5 million IU/ 1.5 mL
A. 89.6oF 37.5 million IU/ 1.5 mL
B. 74oF 75 million IU/ 1.5 mL?
C. 2oF A. 22.5 million IU/ 1.5 mL
D. 77.7oF B. 37.5 million IU/ 1.5 mL
E. 98.6oF C. 75 million IU/ 1.5 mL
D. Any of these
16. A patient comes to the pharmacy with the following E. None of these
prescription:
Rx 20. A patient has been prescribed 20 mEq of potassium
Nitroglycerin 0.3 mg SLrep. prn q 5 min up to 3 min; chloride. How may mEq of KCl would provide this
Use at the first sign of angina; Seek medical attention if prescribed quantity?
no relief A. 1500 mg
Interpret the directions to the patient. B. 1490 mg
A. Take one tablet by mouth every 5 minutes as needed, C. 1380 mg
may repeat 3 times D. 1270 mg
B. Place one tablet under the tongue, repeat every 5 E. 1100 mg
minutes as needed up to 3 times
C. Place one tablet subcutaneously as needed, repeat 21. Determine the concentration of normal saline
every 5 mins for up to 3 times solution in mmol/L.
D. Dissolve one tablet in water and take every 5 minutes A. 153.9 mmol/L
as needed up to 3 times B. 175.2 mmol/L
E. Place one tablet under the tongue, repeat every 5 C. 146.7 mmol/L
minutes every day as needed. D. 124.3 mmol/L
E. 77.2 mmol/L

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22. If a liter of intravenous fluid contains 10% dextrose
and 40 mEq of Na (as NaCl), calculate the percent
strength of sodium chloride in the solution. (𝑀𝑊𝑁𝑎𝐶𝑙 =
58.5)
A. 0.4 % NaCl
B. 0.10 % NaCl
C. 0.3 % NaCl
D. 0.7 % NaCl
E. 0.2 % NaCl

23. A solution contains 330 mg of K+ (MW=39) ions per

1000 mL. How many milliosmoles are represented in the
solution?
A. 8.5 mOsmol
B. 7.2 mOsmol
C. 3.4 mOsmol
D. 4.2 mOsmol
E. 2.1 mOsmol

24. A pediatric patient received 100 mL of an infusion at

10 drops per minute with an administration set that
delivered 60 drops per mL. Determine the duration of the
infusion in minutes.
A. 12 hours
B. 10 hours
C. 6 hours
D. 60 hours

25. An intravenous infusion contains 5 mg of zoledronic

acid 100 mL . If this is to be administered in 20 minutes,
how many mg of zoledronic acid and milliliters of infusion
must be administered per minute? If a drip set that
delivers 15 drops per mL is used, how many drops per
minute must be infused?
A. 0.25 mg/min; 5 mL/min; 75 drops/min
B. 0.5 mg/min; 10 mL/min; 75 drops/min
C. 0.75 mg/min; 5 mL/min; 55 drops/min
D. 0.45 mg/min; 7 mL/min; 65 drops/min
E. 0.55 mg/min; 8 mL/min; 77 drops/min

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