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2 CHANDLER et al
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Excluded from the study were cases of any other single year of age age: 7.2, 95% CI: 6.1–8.2, median:
where the battery was not (n 5 19 226, 27.3%) (Fig 1). 6]), and mouth exposure (n 5 1297,
swallowed intact (n 5 47) and cases 1.8% [mean age: 5.2, 95% CI:
where the battery was in the mouth From 2010 to 2017, the rate of 3.7–6.7, median: 4]). Ear insertion
but did not result in chemical burns battery-related ED visits per was the only exposure route for
(n 5 36), resulting in a final sample 100 000 children increased which patients aged 6 to 17 years
of 2785 unweighted cases. significantly among both those aged predominated (n 5 1118, 64.3% of
<18 years (7.0–14.3, respectively; ear insertions), and this age group
Statistical Analysis P 5 .03) and #5 years (16.8–38.4, was 9.62 times (95% CI:
Data were analyzed by using Stata respectively; P 5 .03), followed by a 8.74–10.59) more likely to present
14.2 statistical software. National nonsignificant decrease among both with an ear insertion than patients
estimates were calculated using age groups from 2017 to 2019 aged #5 years.
CPSC-provided statistical weights. (14.3–8.7, P 5 .28, and 38.4–22.8,
The CPSC considers a national P 5 .27, respectively) (Fig 2). There Table 3 displays the characteristics
estimate to be unstable and was also a nonsignificant decrease of ingestion cases compared with all
potentially unreliable when: (a) the among both age groups from 2013 other exposure routes combined.
estimate is <1200, (b) the to 2015 (9.7–6.9, P 5 .31, and Patients in both the ingestion and
unweighted number of cases is <20, 25.7–17.4, P 5 .31, respectively). noningestion groups were
or (c) the coefficient of variation The rate among children aged 6 to predominately aged #5 years
exceeds 33%. Estimates not meeting 17 years remained relatively (n 5 53 800, 85.0%, and n 5 5418,
these stability requirements were unchanged during the study period 77.0%, respectively) and male
noted as such in results tables. Data and was the same in 2010 as in (n 5 36 003, 56.9%, and n 5 4328,
from the US Census Bureau were 2019 (2.0 per 100 000 children). 61.5%, respectively). There was no
used to calculate population-based change in the proportion of patients
Among all patients, 12.0% who were hospitalized when
rates.28 Statistical analyses included
(n 5 8410) were hospitalized comparing ingestion to noningestion
the calculation of relative risks with
(Table 2). Patients aged 6 to cases.
95% confidence intervals (CIs).
17 years were 1.65 times (95% CI:
Simple or piecewise linear regression
was performed, as appropriate, to
1.58–1.73) more likely to be Two-thirds (n 5 43 415, 68.6%) of
hospitalized than patients aged ingestion cases were confirmed
evaluate the statistical significance of
#5 years. Of cases where battery ingestions. Patients with confirmed
secular trends using a 5 0.05. This
type was described (n 5 48 642, battery ingestion were 1.98 times
study was determined exempt from
69.2% of cases), most involved BBs (95% CI: 1.87–2.08) more likely to
review by the institutional review
(n 5 41 175, 84.7%). Of cases where be hospitalized than those with
board at Children’s National Hospital.
the battery’s intended use was suspected ingestions. Where battery
described (n 5 25 880, 36.8% of type was described for ingestion
RESULTS cases), the most frequently were (n 5 43 937, 69.4%) and
There were 70 322 battery-related watches (n 5 7696, 29.7%) and noningestion (n 5 4705, 66.8%)
ED visits among children aged <18 toys/games (n 5 7458, 28.8%), cases, BBs were most frequent
years from 2010 to 2019, for an followed by hearing aids (n 5 2679, (n 5 37 109, 84.5%, and n 5 4066,
annual average of 7032 per year, or 10.4%), remote controls (n 5 2524, 86.4%, respectively). Among all
9.5 visits per 100 000 children 9.8%), flashlights (n 5 1653, 6.4%), cases, BB ingestions were 2.1 times
(Table 1). The ED visit rate was and all other product types (95% CI: 1.92–2.30) more likely to
highest among children aged #5 (n 5 3870, 14.9%). result in hospitalization than
years compared with children aged cylindrical battery ingestions. The
6 to 17 years (24.5 and 2.2 per Exposure Routes
likelihood of BBs being the ingested
100 000, respectively [mean age: Among all patients, ingestions were battery type was about the same
3.2 years, 95% CI: 2.93–3.42, the most frequent exposure route (n among patients aged #5 years
median: 2 years]). Most patients 5 63 281, 90.0% [mean age: 3.0, compared with patients aged 6 to
(n 5 59 218, 84.2%) were aged 95% CI: 2.8–3.2; median: 2]), 17 years (relative risk: 1.03; 95% CI:
#5 years and more than half followed by nasal insertion 1.02–1.04).
(n 5 40 311, 57.4%) were male. (n 5 4006, 5.7% [mean age: 3.5,
One-year-olds had the greatest 95% CI: 3.1–3.9, median: 3]), ear When the trend in ED visits for
number of battery-related ED visits insertion (n 5 1738, 2.5% [mean battery ingestions alone is
Estimated
Characteristic Actual Sample National Estimate (%)a 95% CI Rate per 100 000 Children National Estimate (%) Rate per 100 000 Children
Total 2785 70 322 (100.0) 51 275–89 369 9.5 65 788 (100.0) 4.6
Age, y
#5 2322 59 218 (84.2) 42 657–75 779 24.5 51 618 (78.5) 10.8
6–17 463 11 104 (15.8) 8080–14 127 2.2 14 170 (21.5) 1.5
Sex
Male 1633 40 331 (57.4) 29 200–51 462 10.7 39 517 (60.2) 5.4
Female 1152 29 991 (42.7) 21 641–38 341 8.3 26 156 (39.8) 3.8
a
Column percentages may not sum to 100.0% due to rounding.
considered, there was a significant both children aged <18 years and The significant increase in battery-
increase among both children aged children aged #5 years in the rates related ED visits among children
<18 years (5.6–13.5, respectively; of overall battery ingestions (8.6–6.1, aged <18 years observed from 2010
P 5 .02) and children aged #5 years P 5 .29, and 22.9–15.8, P 5 .19, to 2017 appears to have been
(12.6–36.4, respectively; P 5 .02) respectively) and BB ingestions alone primarily driven by a 2.3-fold
from 2010 to 2017, followed by a (5.6–3.8, P 5 .08, and 14.4–9.4, increase in the rate among the #5-
nonsignificant decrease among both P 5 .09, respectively). year-old age group between the 2
age groups from 2017 to 2019 study periods. Although a
(13.5–8.2, P 5 .303, and 36.4–21.9, nonsignificant decrease in rates was
DISCUSSION
P 5 .296, respectively). For BB observed from 2013 to 2015, the
ingestions alone, the ED visit rate per The battery-related ED visit rate per
reason for this is unknown.
100 000 children increased 100 000 children has continued to
rise in the last decade and was 2.1
significantly from 2010 to 2017, both In alignment with Sharpe et al,12
among children aged <18 years times higher during 2010 to 2019
ingestions were the most common
(2.6–7.1, respectively; P 5 .02) and compared with 1990 to 2009 (9.5
exposure route, with children aged
children aged #5 years (6.1–19.3, and 4.6 per year, respectively).12
#5 years accounting for 85%
respectively; P 5 .03), followed by a There was an average of 1 battery-
(n 5 53 800) of ingestion cases.
nonstatistically significant decrease related ED visit every 1.25 hours
Previous research has similarly
among both groups from 2017 to among children aged <18 years
found that a smaller proportion of
2019. Similar to the overall trend, during 2010 to 2019 compared with
battery ingestion cases involve older
there was, again, a nonsignificant 1 battery-related ED visit every 2.66
children, although those cases tend
decrease from 2013 to 2015 among hours during 1990 to 2009.12
to have less severe outcomes.5,11,12
This may be partly due to younger
children having a smaller esophagus
and thus being predisposed to
esophageal foreign body impaction.
Furthermore, parents and caregivers
may be unaware that a young child
has ingested a battery until
significant and often life-threatening
symptoms develop. In the current
study, battery-related ED visits were
more frequent among 1-year-olds
than any other single year of age,
and the mean patient age between
the 2 study periods decreased from
FIGURE 1 3.9 years to 3.2 years,12 indicating
Estimated number of battery-related ED visits among children aged <18 years by age, United States, that children presenting at EDs may
2010–2019. be getting younger.
4 CHANDLER et al
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being significantly worse for
ingestions of $20 mm lithium-
powered BBs and children aged <4
years.15 Further, 12.6% of children
aged <6 years who ingested a $20
mm BB suffered a major effect such as
tracheoesophageal fistula, esophageal
perforation, fistulization into major
vessels, esophageal strictures,
spondylodiscitis, or vocal cord
paralysis.15 A mechanism for improved
reporting directly by medical
professionals who manage these cases
FIGURE 2
Annual rate of battery-related ED visits among children aged <18 years old by age group and year, may allow for more detailed reporting
United States, 2010–2019. and understanding of BB ingestion
treatment and outcomes. One example
is the recently developed GIRC app
Where battery type was known, BBs regarding outcomes after patient (Google Play and App Store, www.
accounted for similar proportions of discharge from the ED, the rise in globalirc.org), a free, Health Insurance
ingestions among children aged <18 the proportion of battery-related Portability and Accountability Act-
years for both study periods (84.5% hospitalizations between the compliant smartphone application for
during 2010–2019 and 83.8% 1990–2009 and 2010–2019 study clinicians to anonymously report
during 1990–2009).12 The significant periods may indicate that injuries pertinent injury details, including up to
increase in BB ingestions among are increasing in severity. Other 3 photographs of the BB or other
children aged <18 years found by reports have confirmed increasing object removed, symptom severity,
Sharpe et al12 also continued during incidence of injury severity and removal techniques, complications,
the first 8 years of the current study death after BB ingestions that has treatment provided, and clinical
period, driven by increases among the paralleled the introduction and outcomes, to a centralized, global
#5-year-old age group. This increase increased use of larger ($20 mm database.32
may reflect an increase in BB- diameter), 3-voltage lithium BBs in
powered products in the home, the home.10,15,25,30,31 Litovitz et al When intended battery use was
leading to increased exposure.8,16,29 reported a 6.7-fold increase in the described, toys/games, watches, and
proportion of BB ingestions hearing aids predominated;
Although the NEISS does not resulting in major or fatal outcomes however, the proportion of batteries
provide detailed information from 1985 to 2009, with outcomes intended for watches increased from
TABLE 2 Disposition, Battery Exposure Route, and Battery Type Involved Among Children <18 Years of Age Presenting to US Emergency Departments
for Battery-Related Exposures, Comparing 2010–2019 and 1990–2009
% National Estimatea National Estimate
Actual Sample National Estimate Estimated 95% CI Percentage Point Change
Characteristic 2010–2019 2010–2019 2010–2019 2010–2019 1990–200912 1990–200912 to 2010–2019
Dispositionb
Not hospitalized 2394 61 911 45 113–78 710 88.0 92.6 4.6
Hospitalized 391 8410 5725–11 095 12.0 7.3 4.7
Exposure route
Ingestion 2482 63 281 45 916–80 646 90.0 76.6 13.4
Nasal insertion 185 4006 2741–5272 5.7 10.2 4.5
Ear insertion 82 1738 1078–2398 2.5 5.7 3.2
Mouth exposure 36 1297 453–2141 1.8 7.5 5.7
Battery typec
Button 1714 41 175 27 864–54 486 84.7 83.8 0.9
Cylindrical 283 7467 5340–9594 15.4 16.2 0.8
a
Column percentages may not sum to 100.0% due to rounding.
b
For comparison purposes, “admitted” and “transferred to another hospital” disposition categories reported by Sharpe et al were grouped in the current study as “hospitalized,”
and “treated and released,” and “other” were grouped as “not hospitalized.”
c
Battery type could not be determined for 30.8% (n 5 21 680) of estimated cases in the current study and 35.2% (n 5 23 133) of estimated cases in Sharpe et al.
Estimated Estimated
Characteristic Actual Sample National Estimate (%) 95% CI Actual Sample National Estimate (%) 95% CI
Total 2482 63 281 (100.0) 45 916–80 646 303 7041 (100.0) 4947–9134
Age, y
#5 2082 53 800 (85.0) 38 530–69 070 240 5418 (77.0) 3775–7061
6–17 400 9481 (15.0) 6919–12 043 63 1623 (23.0) 890–2355
Sex
Male 1438 36 003 (56.9) 25 696–46310 195 4328 (61.5) 3005–5651
Female 1044 27 278 (43.1) 19 717–34 840 108 2713 (38.5) 1657–3768
Disposition
Not hospitalized 2132 55 724 (88.0) 40 435–71 014 262 6187 (88.0) 4247–8128
Hospitalized 350 7557 (12.0) 4998–10 115 41 854a (12.0) 472–1235
Battery typeb
Button 1532 37 109 (84.5) 24 759–49 459 182 4066 (86.4) 2725–5408
Cylindrical 261 6828 (15.5) 4787–8868 22 639a (13.6) 140–1139
a
National estimate is potentially unstable because the national estimate is <1200 or the coefficient of variation is >33%.
b
Battery type could not be determined for 30.6% (n 5 19 345) of estimated ingestion cases and 33.2% (n 5 2335) of estimated cases with other exposure routes.
13.7% during 1990 to 200912 to formed by the American Academy of signed into law. This new law will
29.7% during 2010 to 2019. The Pediatrics and American Broncho- require the CPSC to develop
leading products identified during Esophagological Association as a child-resistant testing standards for
both study periods align with multidisciplinary effort of BB packaging and BB-powered device
previous analyses of calls to poison representatives from relevant battery compartments, and that
centers for the management of organizations in industry, BB-powered devices include labeling
battery exposures in the United government, poison control, clinical clearly identifying ingestion risk and
States and Australia.713 Litovitz et al medicine, and public health to develop, instructing consumers to keep such
reported that, in 61.8% of calls to coordinate, and implement strategies products out of reach of young
the National Battery Ingestion to reduce the incidence of BB injuries children.30
Hotline in the US, children had in children.10 Although the National
obtained the battery themselves Button Battery Task Force also BB manufacturers have also
directly from the product.13 supports education of parents and introduced features to prevent
caregivers, they recognized that ingestions, including child-resistant
Although the decreases in rates of education alone is not enough and packaging and hazard warning
overall battery- and BB-related ED have advocated for voluntary labels.14 In 2020, Duracell released a
visits from 2017 to 2019 did not standards addressing product design BB option with a nontoxic bitter
reach statistical significance, they and packaging.17 Standards such as coating to try to discourage
may signal the beginning of a UL60065 and UL4200A require that ingestions; however, use of
downward trend attributable to lithium battery compartments require bitterants has not prevented
multisectoral prevention initiatives 2 or more independent movements or ingestion of other hazards, so the
in recent years. Prevention efforts the use of a tool to open them. In efficacy of this approach with BBs
initially focused only on preventing 2017, the CPSC updated ASTM has yet to be established.34–36 Other
exposure to BBs and educating F963–17 to require that BB-powered industry efforts are targeted toward
parents and other caregivers about toys intended for children aged <14 reducing injury severity in the event
the hazards BBs present. For years include warning labels and of BB ingestion. For example,
example, in 2011, Safe Kids instructions to inform consumers of Landsdowne Laboratories has
Worldwide and Energizer partnered BB risks. Although these standards are designed an innovative technology
to launch the “Battery Controlled” an improvement, they have yet to be (ChildLok), which aims to reduce
campaign, which used media and expanded to include all BB-containing liquefactive tissue necrosis when a
community outreach to spread household items commonly associated BB becomes lodged in the
public awareness of the risks of BB with child exposure. In August 2022, esophagus.37 If proven effective,
ingestion.33 In 2012, the National “Reese’s Law” was passed by the US such safety technologies should
Button Battery Task Force was Congress with bipartisan support and immediately be widely adopted by
6 CHANDLER et al
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battery manufacturers. resulted in an ED visit and, thus, critical for informing a public health
likely underestimates the actual response, including evaluation of the
Another issue is safe disposal of number of battery-related exposures effectiveness of current safety
BBs. BBs no longer powering a among children given it does not standards and public education
device may still have enough include patients treated in non-ED efforts.
residual charge to cause injury when health care settings. Battery type,
lodged inside the body, yet current intended use, and exposure routes CONCLUSIONS
packaging does not clearly define were ascertained using the NEISS Using a nationally representative
safe disposal after removal from a narratives, which are often limited sample, this study found that
device. A recent study involving and inconsistent in level of detail, previously reported significant
wrapping BBs bidirectionally in which could lead to misclassification increases in battery-related ED visits
common household tapes found no in the current study. In addition, among children aged <18 years in
further drop in voltage, no change in specific battery size and chemical the United States during 1990 to
esophageal tissue pH, and no visible composition are typically not noted 2009 continued through 2017, after
tissue injury in esophageal tissue in the NEISS narratives, limiting the which there was a nonsignificant
models, suggesting a safer disposal identification of specific battery decrease until 2019. Ingestion was
solution. However, the authors types. Unfortunately, the NEISS does the most common route of exposure
caution that taped BBs should still not provide information on and children aged #5 years had the
be removed emergently if treatment details, complications, or highest ED visit rate. Unfortunately,
swallowed. longer-term outcomes. despite all existing injury prevention
Finally, novel clinical mitigation efforts, battery-related ED visits
Finally, data on battery exposure are remain too frequent. Regulatory
strategies for reducing the rate of not available, so population estimates
injury pre- and post-removal have efforts and adoption of safer BB
were used to calculate rates. As a designs by industry to reduce or
been developed for esophageal BB result, it is unknown whether changes
impactions and incorporated into eliminate ingestion injuries in
in rates are attributable to increased children are critically needed.
the National Capital Poison Center
exposure, increased severity, changes in
Button Battery Ingestion Triage and
health-seeking behaviors of parents and
Treatment Guideline.14,15,18,38
caregivers, or changes in treatment ABBREVIATIONS
Although not a substitute for
protocols for battery-related ingestions
emergent BB removal from the BB: button battery
resulting from increased education and
esophagus, these strategies can be CI: confidence interval
awareness-raising efforts.
considered to help slow the rate of CPSC: US Consumer Product
injury during emergency Despite these limitations, the major Safety Commission
transportation. strength of the NEISS is that it is the ED: emergency department
only nationally representative FBI: foreign body ingestion
LIMITATIONS sample of battery-related injuries NEISS: National Electronic Injury
This study has several limitations. treated in US EDs. As such, the Surveillance System
The study sample is limited to NEISS allows for the evaluation of
battery-related exposures that incident trends over time, which is
in a leadership position on the National Button Battery Task Force; and serves on the medical advisory board of the Global Injury Research Collaborative,
which is a US Internal Revenue Service-designated, 501(c)(3) nonprofit organization. The other authors have indicated they have no potential conflicts of
interest relevant to this article to disclose.
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American Association of Poison Control 3. Heim SW, Maughan KL. Foreign bod- 5. Orsagh-Yentis D, McAdams RJ, Roberts
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8 CHANDLER et al
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