The growth hormone secretagogue receptor (GHS-R), also known as the ghrelin receptor, is a G protein-coupled receptor located primarily in the hypothalamus, specifically the ventromedial nucleus and arcuate nucleus of the brain. GHS-Rs are also expressed in other brain areas like the ventral tegmental area, hippocampus, and substantia nigra, as well as peripherally in the liver, skeletal muscle, and heart. GHS-Rs bind to ghrelin and regulate energy homeostasis and body weight.
The growth hormone secretagogue receptor (GHS-R), also known as the ghrelin receptor, is a G protein-coupled receptor located primarily in the hypothalamus, specifically the ventromedial nucleus and arcuate nucleus of the brain. GHS-Rs are also expressed in other brain areas like the ventral tegmental area, hippocampus, and substantia nigra, as well as peripherally in the liver, skeletal muscle, and heart. GHS-Rs bind to ghrelin and regulate energy homeostasis and body weight.
The growth hormone secretagogue receptor (GHS-R), also known as the ghrelin receptor, is a G protein-coupled receptor located primarily in the hypothalamus, specifically the ventromedial nucleus and arcuate nucleus of the brain. GHS-Rs are also expressed in other brain areas like the ventral tegmental area, hippocampus, and substantia nigra, as well as peripherally in the liver, skeletal muscle, and heart. GHS-Rs bind to ghrelin and regulate energy homeostasis and body weight.
Growth hormone secretagogue receptor(GHS-R), also known as ghrelin receptor, is a G protein-
coupled receptor that binds growth hormone secretagogues (GHSs), such as ghrelin, the "hunger hormone".(Pradhan, 2013) The role of GHS-R is thought to be in regulating energy homeostasis and body weight. In the brain, they are most highly expressed in the hypothalamus, specifically the ventromedial nucleus and arcuate nucleus. GSH-Rs are also expressed in other areas of the brain, including the ventral tegmental area, hippocampus, and substantia nigra.(Andrews, 2011) Outside the central nervous system, too, GSH-Rs are also found in the liver, in skeletal muscle, and even in the heart.(Yin, 2014)