Name……………………………………………………………………….…….

Roll No………………M/E

DEPARTMENT OF PHARMACY PRACTICE

FACULTY OF PHARMACY, UNIVERSITY OF SINDH JAMSHORO
Third Prof. Pharm-D Second Semester Improver/Failure(Morning/Evening) Examination 2021
Pharmacy Practice VB (Clinical Pharmacy) Course # Pharm 622
Time: 40 minutes. Date: 4/12/2021 Max. Marks: 40
Q.No.01 Instructions: 1. Attempt all questions. 2. Read every question very carefully and
ENCIRCLE the appropriate answer very clearly. UNATTEMPTED Questions/ Overwritten
answers will carry no mark. 3. Use blue or black point pen only. ……………………………..
1. Which of the following is not sign and symptoms of ulcerative colitis?
a) Diarrhea b) Abdominal pain c) Abdominal mass d) None of these
2. Which of the following is not the fundamental Principal of Evidence based medicine?
a) Considering benefits/risks b) Patient expectation c) Patient convenience d) All of these
3. In which type of liver injury there will be more than two fold rise in ALT levels;
a) Hepatocellular b) Chlolestatic c) Mixed d)All of these
4. Which drug is responsible for disruption of calcium homeostasis and liver cell membrane injury?
a) Diclofenac b) Lovastatin c) Frusemide d) Nitrofurantoin
5. According to the WHO in Grade 3 hepatotoxicity, liver enzyme levels are increased up to ?
a)2 times b)2.5 times c)5-10 times d) None of these
6. Which of the following drug is not associated with drug induced hemolytic anemia?
a) Amikacin b)Acyclovir c) Phenobarbital d) Both a and b
7. The dose of propranolol in portal hypertension is?
a) 25 mg OD b) 50mg OD c) 30mg BID d) None of these
8. Which of the following drug causes reduction in renal blood flow and chronic structural changes in the
kidney ?
a) Cisplatin b) Amphotericin c) Tacrolimus d) None of these
9. Which of the following types of drug is/are responsible for renal artery obstruction and severe
hypertension?
a) Immunosuppressant b) Aminoglycosides c) Opioids d) Statins
10. The indexing services are the example of which type of literature?
a) Primary b) Tertiary c) Secondary d) All of these
11. Which one of the following is common place to evaluate the Pharmacokinetic studies in clinical
literature?
a) Phase 3 b) Phase 1 c) Phase 2 d) Both b and c
12. Bone marrow transplants works best in people under ;
a) 20 years b) 30 years c) 40 years d) 50 years
13. Which of the following is the main barrier in online pharmaceutical services?
a) Lack of time b) Lack of skills c) Lack of knowledge d) All of these
14. Which of the following can cause of megaloblastic anemia?
a) Vitamin B2 b) Vitamin B6 c) Vitamin B9 d) None of these
15. Which of the following disease is/are associated with excessive Glomerular damage and excessive loss
of protein in urine?
a)Interstitial nephritis b)Acute tubular necrosis c)Nephrotic syndrome d) All of these
16. Which of the following conjugates is involve in the metabolism of Acetaminophen ?
a)Sulfate conjugates b) Glutathione conjugates c)Glucuronide conjugates d)All of these
17. Which of the following are sign and symptoms of Valproic acid toxicity?
a)Edema b)Jaundice c) Weight gain d) None of these
18. The mortality rate associated with carbamazepine hepatic toxicity is;
a)20% b) 30% c)35% d) 25%
19. Which of the followings are the risk factors for liver injury?
a)Type 2 diabetes b)Genetics c)Autoimmune disorder d)All of these
20. Which of the followings drugs can cause of rhabdomyolysis ?
a)Statins b)ACE inhibitor c)ARB inhibitor d) All of these
Name……………………………………………………………………….…….Roll No………………M/E