- Deficit de carnitina => hipoglicemie

- Vit B si PDH -> in decarbox. Piruvatului

- Icter -> Bt > 2 mg/dL
- Tabel icter
- Ag carcinoembrionar normal 20-40 ng/ml
- Aldehida acetica eliminata de aldehid dehidrogenaza mitocondriala
- Rezultat fals poz. La glucozurie dat. Aportului crescut de vit. C
- Cilindri la renal
- Osmolaritate urina normala >500 mOsm/kg; Na urinar < 40 mEq/l; excretie fractionala a Na<1
- Isuf. Ren. Cr. Compensata: creatinina serica 1,5-3 mg/dL; decompensata >3 mg/dL
- Scheme curs diabet
- Glucoza creste -> SRO creste -> PARP activata -> GAPDH scade -> creste fluxul in calea poliolica,
AGE cresc, PKC creste (-> creste NF-kB), creste fluxul in calea hezoaminelor (=> UDP-GLcNAc)
- Cetoacidoza diabetica det. Rez. Fals crescute ale amilazei serice; acidoza lactica det. Valori fals
scazute ale ALT
- Raport de Ritis = AST/ALT = GOT/GPT = 1,3 (normal)
- IMA: CK tot, CK-MB, transaminaze, LDH, Mb, troponine cardiace I si C
- CK-MB*100/CKtot > 5% => IMA
- Alti factori de risc cardiovasc.: acid uric seric (>4mg/dL), homocisteina serica (>10 µmoli/L)
- Biomarkeri boala cardiovasc: DANIH: dislipidemie, agregare plachete, necroza, inflamatie,
hemodinamici
- Markeri trombocitari: P selectina, CD40L, R. GpIIa/IIIb
- Markeri tumorali: Ag carcinoembrionar (CEA), CA125, α-feto prot., Ag specific prostatic (PSA), CA
19.9