BIOMOLECULES

MULTIPLE CHOICE QUESTIONS

1. Compound ‘A’ (molecular formula C3H8O) is treated with

acidified potassium dichromate to form a product ‘B’
(molecular formula C3H6O). ‘B’ forms a shining silver
mirror on warming with ammoniacal silver nitrate. ’B’
when treated with an aqueous solution of
H2NCONHNH2.HCl and sodium acetate gives a product
‘C’. Identify the structure of ‘C’.
(a) CH3CH2CH=NNHCONH2 (b) CH3C=NNHCONH2
CH3

(c) CH3C=NCONHNH2 (d)CH3CH2CH=NCONHNH2

CH3

Sol. (a)

2. The drug used to cure tubercutosis is

(a) quinine (b) piperazinc
(c) sulphanilamide (d) para-amino salicyclic acid
Sol. (d)
para-Aminosalicyclic acid is used to cure tuberculosis.

3. Which of the following is not true for reserpine?

(a) Reserpine is a tranquilizer.
(b) Reserpine is a non-alkaloid.

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 (c) Reserpine is also known as serpasil.
(d) Reserpine is obtained from the plant Raowolfia
serpentine.
Sol. (b) Reserpine is an alkaloid.

4. Which of the following may be used as antipyretic as well

as analgesic?
(a) Aspirin (b) Chloroform
(c) Alkaloid codein (d) Morphine
Sol. (a)

5. Kwashiorkar is caused by the deficiency of

(a) vitamins (b) hormones
(c) amino acids (d) essential amino acids
Sol. (d)
Essential amino acids are not synthesized by human body.
These have to be supplied from outside in the diet.
The lack of these amino acids causes kwashiorkor.

6. Thymine is held by two hydrogen bonds with the base

(a) guanine (b) cytosine
(c) adenine (d) thymine
Sol. (c)
DNA contains adenine (A), guanine (G), cytosine (C),
thymine (T) bases. But these is uracil (U) in place of
thymine in case of RNA.
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 The pair of complimentary bases are,
A—T; A—U and G—C

7. Which one of the following statements is not correct?

(a) The phenomenon of mutarotatinreferes to the change in
specific rotation of either of the two anomers in solution
with time and attains a constant equilibrium value.
(b) Specific rotation of -D glucose is +18.7º.
(c) Ring structures of sugars can be broken by periodic
acid.
(d) -D glucose in water attains a constant specific rotation
of 112.2º.
Sol. (d)
The constant specific rotation in water with either -D-
glucose or -D-glucose attain is +52.7º.

8. Which one of the following statements is not correct?

(a) Proteins are polyamides formed from amino acids.
(b) Except glycine, all other amino acids show optical
activity.
(c) Natural proteins are made up of L-isomers of amino
acids.
(d) —NH2 and –COOH groups are attached to different
carbon atoms in amino acids.
Sol. (d)

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 In amino acids, —NH2 and —COOH groups are attached to
the same carbon atom.

9. Which one of the following statements is not correct?

(a) The breaking down of large molecules into smaller ones
by organisms is called catabolism.
(b) Catabolic reactions are usually accompanied by the
absorption of energy.
(c) The process of synthesizing a large molecule from
simpler molecules by organisms is known as anabolism.
(d) Anabolic reactions cannot take place without energy.
Sol. (b)
Catabolic reactions are usually accompanied by the release
of energy.

10. What is the number of asymmetric carbon atoms present in

-D-glucopyranose molecule?
(a) Two (b) Three
(c) Four (d) Five
Sol. (d)
CH2OH
H * O H
H
* OH H *
HO OH
* *
H OH

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 The assymmetric C–atom of (D) glucopyranose have been
shown by (*).

11. A sample of (D)–lactic acid was found to have an optical

purity of 72%. How much (L)–isomer is present in the
sample?
(a) 28% (b) 50%
(c) 56% (d) 14%
Sol. (d)
Sample have optically pure (D)–lactic acid as 72%, thus
28% is racemic lactic acid. 28% racemic mixture will
contain 14% (L)–lactic acid.

12. Identify the unknown products (A) and (B) in the given
reaction:
H / 
Glucose + 3 C6H5NH–NH2  Osazone + (A) + (B) +
2H2O
(a) C6H5NH2 and NH3 (b) C6H5NH2 and NH2OH
(c) C6H5NH—NHOH and NH3 (d) NH2OH and H2O
Sol. (a)
H / 
Glucose + 3 C6H5NH–NH2  Osazone + C6H5NH2 +
NH3 + 2H2O
(A) (B)

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13. Diabetes is detected by testing urine of the patient with
(a) Brady’s reagent (b) Nessler’s reagent
(c) Fenton’s reagent (d) Benedict’s solution
Sol. Diabetes is due to disfunctioning of pancreas, which stops
releasing insulin. Due to this sugar is not metabolized and
thus, it is passed in the urine. Benedict’s test can detect the
presence of sugar in the urine.
 (d)

14. The commonest disaccharide has the molecular formula

(a) C10H18O9 (b) C10H20O10
(c) C11H22O11 (d) C12H22O11
Sol. The most common disaccharide is sucrose, whose
molecular formula is C12H22O11.
 (d)

15. Consider following reagents,

(I) Br2 water (II) Tollen’s reagent and (III) Fehling’s
solution. Which reagent(s) can be used to make distinction
between an aldose and a ketose?
(a) (I), (II) and (III) (b) (II) and (III)
(c) (I) only (d) (II) only
Sol. Br2 water oxidises aldose to corresponding acid and it get
decolourised. Ketoses are not oxidised by Br2 water.
 (c)

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 O

16. This structure of glycine (amino acid) is H NCH CO (zwitter 3 2

ion.
Select the correct statement of the following.
(a) Glycine, as well as other amino acids are amphoteric.

(b) The acidic functional group in amino acids is NH . 3

(c) The basic functional group in amino acids is CO . 2

(d) All the statements are correct.

Sol. Glycine and all other amino acids are amphoteric because
of the presence of NH2 and CO2H group both. The amino

acid exists and zwitterion and acidic group is NH while 3

basic group isCO . 2

 (d)

17. The dipeptide, Gly.Ala has structure

O O
 
(a) H NCH CNHCHCO
3 2 2 (b) H NCH CNHCHCO
3 2 2

CH3 CH3
O O
 
(c) O CCHNHCCH NH
2 2 3 (d) O CCH NHCCHNH
2 2 3

CH3 CH3

Sol. By convention, the amino acid with the free amino group
(Nterminus) is written at the left end and the one with the
unreacted carboxyl group (Cterminus) at the right end.
O

Thus, the structure of Gly.Alais H NCH CNHCHCO .
3 2 2

CH3

 (a)

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18. The two forms of Dglucopyranose are
(a) epimers (b) anomers
(c) enantiomers (d) geometrical isomers
Sol. The D(+)glucopyranose
and D(+)glucopyranose
differ in their configuration at
CH2OH CH2OH

first chiral carbon atom. Such H

O
H H
H
O
OH
H

diastereomers are called HO

OH H
OH HO
OH H
H

anomers. H OH
D(+)glucopyranose
H OH
D(+)glucopyranose

 (b)

+ +
NH3 (y) NH3
(z)
19. Acidic order of is
COOH
(x)

(a) (z) > (y) > (x) (b) (y) > (x) > (z)
(c) (x) > (y) > (z) (d) (x) > (z) > (y)
Sol. Since, carboxylic acids are more acidic than ammonium
ions, most acidic would be x. CO2H group exerts a greater
I on aminium group than on aminium group. Thus, y
is more acidic than z.
 (c)

20. Which pair of compounds gives Tollen’s test?

(a) Glucose & Fructose (b) Sucrose & Glucose
(c) Hexanal&Acetophenone (d) Fructose & Sucrose

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Sol. Glucose being an aldehyde gives Tollen’s test while
fructose, which is an hydroxy ketone, tautomerizes to
glucose in basic medium. Hence, it would also give
Tollen’s test.
 (a)

21. Schweitzer's reagent used for dissolving cellulose in the

manufacture of artificial silk is
(a) CuSO .5H O
4 2 (b) CuI
(c) [Cu (NH ) ]SO
3 4 4 (d) Cu(CH COO) .Cu(OH)
3 2 2

Sol. (c)
Cu (NH ) SO isschweitzer’s reagent used for manufacture of
3 4 4

artificial silk.

22. Which one of the following statements is true for protein

synthesis (translation)
(a) Amino acid are directly recognized by m-RNA
(b) The third base of the codon is less specific
(c) Only one codon codes for an amino acid
(d) Every t-RNA molecule has more than one amino acid
attachment site.
Sol. (a)
In the process oftranslation amino acids are directly
recognized by m-RNA.

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23. Which of the following pentoses will be optically active
CHO CHO CHO
| | |
HCOH HCOH HCOH
| | |
HOCH HCOH HCOH
| | |
HCOH HOCH HCOH
| | |
CH 2 OH CH 2 OH CH 2 OH
I II III

(a) All (b) II and III

(c) I (d) II
Sol. A

INTEGER TYPE QUESTIONS

24. A compound of mol. wt. 180 is acetylated to give a
compound of mol. wt. 390. The number of amino groups in
the initial compound is
Sol. Difference in mass of compound = 390 – 180 = 210
wt. of CH CO – group is = 43
3

210
Therefore no. of  NH 2 group =  4.88  5 .
43

25. Starting with three different amino acid molecules, how

many different tripeptide molecules are formed
Sol. (6)
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 Six type of tripeptide molecules are formed.

26. Subunits present in haemoglobin are

Sol. (4)
Four sub units are present in haemoglobin.

27. The number of atoms in the cyclic structure of D-fructose is

Sol. (5)

28. The number of essential amino acids in man is

Sol. (10)
The amino acids which can’t be synthesised by human
body so they are essential to take from diet. They are 10 in
number.

29. In fructose, the possible optical isomers are

Sol. (8)
Fructose has three chiral centres and hence 23 = 8 optical
isomers are possible.

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30. pH in stomach is approximately
Sol. (2)
In stomach medium is strongly acidic. Hence, pH  2 .

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