SGPT (Serum Glutamic-Pyruvic Transaminase), ALT (Alanine Aminotransferase), Interpretations

1/21/23, 10:35 PM SGPT (Serum Glutamic-Pyruvic Transaminase), ALT (Alanine...
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SGPT (Serum Glutamic-Pyruvic Transaminase), ALT (Alanine

aminotransferase), Interpretations
Chemical pathology (https://labpedia.net/category/lab-tests/chemical-pathology/) Lab Tests (https://labpedia.net/category/lab-tests/)
SGPT (Serum Glutamic-Pyruvic Transaminase)

Sample for SGPT (ALT)
1. This is done on the serum of the patient.
2. The Blood sample can be taken at any time.
3. The fasting sample is not necessary.
4. Analyze the enzyme on the same day because the enzyme activity is lost at room temperature.
5. This enzyme is stable in whole blood for up to 12 to 24 hours; after that time, there is a gradual increase due to release from the RBCs.
6. The sample can be stored at 4 °C for 1 to 3 days (ALT is stable when refrigerated).
1. ALT, when freezed, shows deterioration.
Precautions For SGPT (ALT)

1. Avoid hemolysis because RBC contains increased ALT (SGPT) and AST (SGOT).
2. Drugs that may increase the SGPT value are acetaminophen, aminosalicylic acid, ampicillin, allopurinol, cephalosporin, chlorpropamide,
clofibrate, cloxacillin, codeine, indomethacin, INH, Methyldopa, methotrexate, nalidixic acid, quinidine, phenylbutazone, phenytoin, salicylates,
tetracycline, and propanol.
3. Ideally, perform the test as soon as possible or on the same day because the sample’s storage may not be satisfactory.
4. Previous I/M injection may increase the level.
Indications for SGPT

1. Diagnose liver diseases.
2. Monitor liver diseases after the treatment.
3. It differentiates jaundice from liver disease or hemolytic anemia.
Definition of ALT (SGPT):

1. This enzyme catalyzes the reversible transfer of amino groups between an amino acid, and α-keto acids are called aminotransferase or
transaminases.
2. One of the aminotransferases is Alanine aminotransferase (ALT), or the old name was glutamate-pyruvate transaminase (SGPT) which will
catalyze the reversible transfer of the amino group between an amino acid and α-keto acid where vitamin B6 (pyridoxal phosphate) is the co-
factor.
(https://www.labpedia.net/wp-content/uploads/2020/01/SGPT-biochemical-reaction.jpg)
SGPT (ALT) biochemical reaction
Distribution of SGPT (ALT):

1. ALT is an enzyme found predominantly in the liver.
2. It is distributed in many tissues, with a moderate amount in:
1. Kidneys.
2. A small amount in:
3. Heart, skeletal muscles.
3. A minimal amount may be found in the pancreas, spleen, lungs, and RBCs.
Variation of the ALT:

1. The day-to-day variation of the ALT is 10% to 30%, and there is diurnal variation.
2. ALT is 45% higher in the afternoon than in the early morning.
3. Until the age of 15, ALT is higher than the AST; after that, AST is higher than the ALT.
4. In a few people, this pattern may reverse after the age of 60.
5. Exercise is the major determinant for AST but less for ALT in men.
1. Strenuous exercise or bodybuilding increases AST 3-fold and a 50% increase in ALT.
2. The effect of the exercise is minimal in the women.
Distribution of SGPT (ALT) in the liver:

1. This enzyme is present in cytosolic forms in the liver. The majority of the SGPT is present in the cytoplasm of liver cells.
2. There is always a low level of this enzyme in the blood.
3. This is a liver-specific enzyme of the transferases.
Privacy - Terms
4. The liver hepatocytes contain 3 to 4 times more AST (SGOT) than the ALT (SGPT).
https://labpedia.net/sgpt-serum-glutamic-pyruvic-transaminase-alt-interpretations/ 1/55
5. This is also normally found in bile, CSF, and saliva.
6. It is not found in the urine unless there is a kidney lesion.
(https://www.labpedia.net/wp-content/uploads/2020/01/SGPT-liver-cell.jpg)
SGPT distribution in the liver cell
Liver cell injury:
1. Any damage to the liver cells, SGPT enzyme, is released, specifically from liver cell necrosis.
2. First cytosolic SGPT is released, and in the case of necrosis, then mitochondria SGPT is released into circulation.
(https://www.labpedia.net/wp-content/uploads/2020/01/SGPT-cell-injury1.jpg)
SGPT level depends upon the number of liver cells injured
(https://www.labpedia.net/wp-content/uploads/2020/01/SGPT-cell-injury-and-level.jpg)
SGPT level depends upon the number of cells injured
3. SGPT activity persists longer than the SGOT.

4. This enzyme is raised before there are clinical findings of jaundice.
5. In viral hepatitis, the SGPT/SGOT ratio is greater than 1.
6. Other than the viral cause, the SGPT/SGOT ratio is less than 1.
SGPT (ALT) biochemical reaction and variations in different conditions:

1. ALT catalyzes the reaction, and it is reversible.
2. Pyridoxal-5‘- phosphate (P-5-P) functions as coenzymes in the amino-transfer reaction.
1. The P-5-P is bound to the apoenzyme and serves as a true prosthetic group.
2. The P-5-P bound to the apoenzyme accepts the amino group from the first substrate, alanine, to form enzyme-bound pyridoxine-5-
phosphate, and the first reaction product is pyruvate.
3. This coenzyme increases the ALT activity by 20% in the normal serum.
4. Hemolysis increases both AST and ALT because of this enzyme activity in the RBCs compared to serum. This effect is more significant for
AST than ALT.
(https://www.labpedia.net/wp-content/uploads/2020/01/SGPT-reaction-details-1-1.jpg)
SGPT (ALT) reaction principle
SGPT 1.5 to 8 times (mild or nor elevation) more than the normal level seen in:
1. Early, late and subclinical hepatitis.
2. Chronic hepatitis.
3. Alcoholic hepatitis.
4. Alcoholic fatty liver.
5. Laennec’s cirrhosis.
6. Chemical hepatitis.
7. Passive congestion with centrilobular necrosis.
8. Rye’s syndrome.
9. Cholangitis.
10. Hemochromatosis.
11. Pancreatitis.
12. Granulomatous infections.
13. Neoplasia infiltration.
SGPT >8 to 10 times (3 to 10 times than the normal ) more than the normal value seen in:
1. Mostly in acute viral hepatitis.
2. Chronic active hepatitis.
3. Infectious mononucleosis.
SGPT >30 times (20 or more) more than the normal value is seen in:
1. Drug toxicity like acetaminophen in alcoholics and malnourished people.
2. Viral hepatitis.
SGPT level in various tissue as compared to serum:

Compared to serum (1 unit) in the heart is 450 times; the liver is 2850 times, the kidney is 1200 times, skeletal muscle is 300 times, the pancreas is
130, the spleen is 80 times, the lung is 45, and RBCs 7 times.
SGPT (ALT) levels in various tissues as compared to the serum (one unit) are:
Organs Times more as compared to the normal serum level
Liver 2850
Kidneys 1200
Heart 450
Skeletal muscle 300
Pancreas 130
Spleen 80
Lungs 45
RBCs 7
Serum 1
AST/ALT ratio:
1. The ALT is the cytoplasmic enzyme in the liver, while AST is both a cytoplasmic and mitochondrial enzyme with a wide distribution in various
other tissues.
1. AST/ALT ratio is typically <1, but infectious hepatitis becomes greater in the liver.
2. AST/ALT ratio is usually greater than 1 is seen in:
1. The patient with alcoholic liver disease (cirrhosis). AST is more sensitive to alcoholic liver disease.
2. Liver congestion.
3. Metastatic tumor of the liver.
3. AST/ALT ratio of less than 1 is seen in:
1. Acute hepatitis.
2. Viral hepatitis.
4. The ratio will be less accurate if the AST level is more than 10 times the normal.
Ratio of enzymes AST/ALT = <1 AST/ALT = >1
AST/ALT 1. Acute hepatitis 1. Alcoholic liver diseases (Cirrhosis)

2. Viral hepatitis with extensive 2. Alcoholic patient with acetaminophen,
hepatocellular necrosis causing extensive liver cell necrosis.
3. Infectious mononucleosis 3. Liver congestion
4. Metastatic tumor infiltration of the liver
5. Myocardial infarction
6. Rhabdomyolysis
7. Hemolytic anemia
Diagnostic application of the SGPT (ALT):

1. The best indicator for liver cell injury is when both SGPT and SGOT are raised.
1. Higher-level are found in hepatocellular disorders than the extrahepatic or intrahepatic obstructive lesions.
2. Levels of both enzymes may reach as high as 100 times. 20 to 50 times, the elevated level is frequently found.
2. Measuring aminotransferases weekly is useful in hepatitis or other hepatic injuries.
3. Because of the accurate measuring techniques, it can detect liver cell injury due to alcohol.
4. It is used as a screening test for diagnosing hepatitis due to hepatotropic viruses, especially the hepatitis C virus in blood donors.
5. 5 to 10 times the elevation of ALT and AST occurs in the liver’s metastatic carcinoma. AST (SGOT) level is higher than the ALT (SGPT). In the early
stages of malignant infiltration of the liver, these enzymes are normal.
6. ALT (SGPT) may be raised after intake of alcohol, delirium tremors, and after the administration of the drugs like opiates, salicylates, and
ampicillin.
NORMAL SGPT (ALT) level

Source 4
Age Male U/L Female U/L
Newborn 12 months 13 to 45 13 to 45
one to 60 years 10 to 40 7 to 35
60 to 90 years 13 to 40 10 to 28
>90 years 6 to 38 5 to 24
Source 2
Adult / child = 4 to 36 unit/L at 37 °C

Elderly = slightly higher than the adult
Infants = Maybe twice high as the adult
Another source
Men = 10 to 30 units /L (some labs normal is 10 to 40 U/L).

Women = 9 to 25 units /L (Some labs normal is 10 to 28 U/L).
Children are two times of adult’s value.
In children, it is raised because of bone activity, which is normal for children.
The adult level is achieved by 6 months of age.
Males are slightly higher than females.
The increased SGPT (ALT) level is seen in:

1. Viral hepatitis. There is a markedly increased level.
2. Drug-induced hepatitis.
3. Chronic hepatitis.
5. Intrahepatic cholestasis.
6. Cholecystitis.
7. Active cirrhosis.
8. Metastatic tumors of the liver.
9. Obstructive jaundice.
10. Alcoholic cirrhosis.
11. The mild increase is seen in :
1. Myosotis.
2. Pancreatitis.
3. Myocardial infarction.
4. Shock.
12. Alcohol-acetaminophen syndrome.
13. A significant increase in level has been in acute liver diseases.
1. A moderately increased level is seen in chronic liver diseases and muscle trauma.
2. A mildly increased level is seen in myositis, Myocardial infarction, and infectious mononucleosis.
Acute Viral hepatitis SGPT (ALT) Pattern:

1. This rises before the appearance of jaundice.
2. The peak level occurs between 7 to 12 days of jaundice.
3. Then there is a gradual decrease in the level.
4. Normal level after 3 to 4 weeks of the onset of jaundice.
5. AST/ALT ratio, which is normally <1, becomes greater > than 1.
(https://labpedia.net/wp-content/uploads/2020/01/SGPT-curve-Viral-heptI-1-1.jpg)
SGPT level in Viral hepatitis
Table showing the increase of SGPT in various conditions:
Clinical Condition The Rise In SGPT Level With Reference To The Normal
Value
Viral hepatitis and liver diseases may reach 100 times
Infectious hepatitis ALT > AST
Toxic hepatitis Extremely high level
Infectious mononucleosis 20 times
Intrahepatic cholestasis maybe raised
Extrahepatic cholestasis Very high level
Cirrhosis 4 to 5 times or higher
Metastatic carcinoma 5 to 10 times
Acute myocardial infarction within normal limits or a very mild increase
Progressive muscular dystrophy May reach 8 times
Dermatomyositis May reach 8 times
Critical value:
>9000 U/L seen in Alcohol-acetaminophen syndrome.

This level can distinguish it from alcoholic or viral hepatitis.
Comparison of AST/ALT
1. AST (SGOT) is always raised in acute myocardial infarction, where ALT (SGPT) will be normal unless there is damage to the liver.
2. ALT (SGPT) is more raised in acute hepatobiliary obstruction than AST (SGOT).
3. ALT (SGPT) is more specific than AST (SGOT) for liver cell injury.
4. The AST/ALT ratio is higher in alcoholic liver diseases.
5. AST (SGOT) is more sensitive to alcoholic liver cell injury.
The main feature of SGPT (ALT) and SGOT (AST):

Clinical parameters SGPT (ALT) SGOT (AST)
Normal range 5 to 35 IU/L 10 to 40 IU/L
Half-life in blood 35 to 57 hours (3 to 5 days) 12 to 22 hours
Distribution in the body 1. Main is the liver 1. It is more in the heart than liver
2. Low concentration in other tissues 2. It is present in skeletal muscles, brain,
and kidneys
Location in the liver cells It is present in the cytoplasm only It is present in cytoplasm and mitochondria
Change with acute inflammatory conditions It is extremely sensitive It is moderately sensitive
The rise in metastatic or primary neoplasm It is moderate or no change It is markedly increased
In cirrhosis It is a mild to moderate increase It is moderately increase
In acute myocardial infarction It is a mild to moderate increase It is markedly increase
Question 1: What is the half-life of SGPT?

Show answer
Question 2: What is the best indicator of liver cell injury, SGOT or SGPT?
Show answer
Question 3: Is there any role of RBCs hemolysis in the level of SGPT.
Show answer
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Comments
Raja Mondal Reply

 July 21, 2020
MY SGPT is 88 U/L and SGOT is 63. What kind of prevention should taken by me . I am just 24
Dr. Riaz Reply

 July 21, 2020
You should have a complete Liver function test and viral hepatitis profile. Keep on checking SGPT and SGOT at least every three months.
jahangeer Khan Reply

 August 13, 2020
My son’s test report is SGPT (ALT) 90 plaease tell me how to treat it and what medicine to use
Dr. Riaz Reply

 August 13, 2020
Dear
This SGPT is raised. Please advise complete liver function test with viral profile HBV, HCV. Then best is to consult some good hepatologist or physician.
Tarun Reply
 August 26, 2020
My SGOT IS 51
SGPT IS 72
What to do
Dr. Riaz Reply

 August 26, 2020
You should have a complete liver function test and hepatitis profile (HBV, and HCV). If these are abnormal then consult the physician.
Lenard Concepcion Reply

 September 6, 2020
Good day,
my sgpt is 56 U/L
my sgot is 59 U/L
I’m 34 y/o male. had muscle pain a few days ago due to my new squat exercise routine before taking this test. Is my muscle pain connected with my
sgpt sgot levels? should i be worried? thank you
Dr. Riaz Reply

Dear SGOT/SGPT are raised. You should have total bilirubin, direct and indirect, alkaline phosphatase, and gamma GT level. If these are raised then please
consult physician for further work-up.
Samidha Reply
My SGPT 79 & SGOT 48 & GGTP 75
Please suggest
Dr. Riaz Reply

Please advise liver function tests including viral profile and ultrasound abdomen. Consult some good physicians.
Samidha Reply
My SGPT 79 SGOT 48 GGTP 75
Please suggest
Dr. Riaz Reply

Please advise liver function tests and ultrasound of the abdomen. Consult some good physicians.
Ratan roy Reply

 October 17, 2020
My bilirubin 15.5 and sgpt 250 what should I do?
Dr. Riaz Reply

 October 17, 2020
Bilirubin is too high. Please advise the complete liver function test, ultrasound abdomen, and consult a good physician.
il jahan Reply
November 6, 2020
y alt sgpt is 10 U/l
it normal
Riaz Reply
vember 7, 2020
e it is normal.
Shreya gupta Reply

 October 21, 2020
Hi i am 24 year old female i have SGOT 52and SGPT 81.5 what should i do. Else every thing in my liver and blood profile is normal.
Dr. Riaz Reply

 October 21, 2020
Please check your hepatitis viral profile. Please rule out any medication. Even aspirin can disturb the LFT.
Mitesh m Darji Reply

 November 10, 2020
i m covid patient and my SGPT is 101. and CRP lavel is 0.6 so please suggest what to do
Mitesh m Darji Reply

hi
i m covid patient and my sgpt is 101
Dr. Riaz Reply

Please advise complete liver function tests to find any other abnormal values. You definitely need treatment for the Covid. Now, a day’s most doctors are
prescribing steroids. Please consult some good physicians.
havar Reply
December 11, 2021
y sgpt is 110 in liver function test rest is in normal range what it say
Fardosh Reply
Hi my mum 54 years old and her SGPT 52 is it normal.
Dr. Riaz Reply

It is the upper limit. Please advise the complete liver function test.
Rajat Bajaj Reply

My sgot is 33 and SGPT 72, is it serious ?
age 32 M
tested in fever 100 F
Dr. Riaz Reply

SGOT is normal, but SGPT is mildly raised which may be due to some medicine like Aspirin. Please repeat after 2 weeks.
Mary Reply
My lft result
Liver Function Test. Normal
Bilirubin -Total. : 0.5 mg/dl. 1. 0
Bilirubin – Direct. : 0.2 mg/dl upto 0.4
Bilirubin Indirect. : 0.3 mg/dl 0.2-0.6
SGOT/AST;Aspartate Aminotransferas
: 29 U/L Males : upto 35 U\L
Females : upto 31 U\L
SGPT/ALT;Alanine Aminotransferase
: 34 U/L Males : upto 45 U\L
Femaless : upto 34 U\L
Alkaline Phosphatas. : 78 IU/L
Adults : 18 – 115
Upto 12 yrs : 54 – 369
Total Protein. : 6.4 gm/dL
6 .4 – 8.3 g/dl
Albumin Serum. 3.7 gm/dL
3.5 – 5.5
Globulins. : 2.7 gm/dL 1.8 – 3.4
A/G Ratio. : 1.4:1 2:1
Technology used : Automated procedure On EM 200
I am 51 years
Some values are in boundary
What it indicate
Need more test?
Dr. Riaz Reply

Mostly your tests are in the normal range. I don’t think so. If you have any symptoms then consult a physician and do the tests which he/she thinks are
needed.
Liton Saha Reply

 December 21, 2020
MY SGPT is 28 U/L and (HBV) DNA is Undetected. What kind of prevention should taken by me . I am just 35
Dr. Riaz Reply

Vaccination for HBV infection is available. I will suggest you get vaccinated.
Akhlaq Ahmed Reply

Hi Dr. Riaz, I am diabetic patient and a stone in my gallbladder with no pain, four months ago SGPT result was 44 U/L , recent test result SGPT is 66 U/L.
my age is 41.
Dr. Riaz Reply

I will suggest to control diabetes and get operated on for gall stones. I will suggest consulting the surgeon because gall stones may give rise to a mild
increase in liver enzymes.
Prabhat kumar singh Reply

 January 6, 2021
TEST NAME TECHNOLOGY VALUE UNITS NORMAL RANGE
ALKALINE PHOSPHATASE PHOTOMETRY 74.6 U/L 45 – 129
BILIRUBIN – TOTAL PHOTOMETRY 0.79 mg/dl 0.3-1.2
BILIRUBIN -DIRECT PHOTOMETRY 0.25 mg/dl < 0.3
BILIRUBIN (INDIRECT) CALCULATED 0.55 mg/dl 0-0.9
ASPARTATE AMINOTRANSFERASE (SGOT ) PHOTOMETRY 128.73 U/l < 35
ALANINE TRANSAMINASE (SGPT) PHOTOMETRY 90.6 U/l < 45
GAMMA GLUTAMYL TRANSFERASE (GGT) PHOTOMETRY 17.5 U/l < 55
PROTEIN – TOTAL PHOTOMETRY 9.05 gm/dl 5.7-8.2
ALBUMIN – SERUM PHOTOMETRY 5.2 gm/dl 3.2-4.8
SERUM GLOBULIN PHOTOMETRY 3.85 gm/dL 2.5-3.4
SERUM ALB/GLOBULIN RATIO CALCULATED 1.35 Ratio 0.9 – 2
Please correlate with clinical conditions
Please sugges me what I have to do…..
Is this a indication of liver cerosis
Dr. Riaz Reply

 January 6, 2021
Most tests are normal except for SGOT and SGPT. Please rule out alcohol intake and pain killers.
Shashvat dubey Reply

 January 8, 2021
Hi Sir,
My SGOT – 62.88
SGPT – 132.41
Serum bilirubin – 0.41
Direct – 0.19
Indirect – 0.22
Serum protein – 6.94
Serum Alkaline phosphatase :- 68.86
Albumin – 4.78
Globulin – 2.16
A/G ratio – 2.21
My age 32 .
Is their any thing serious ?
Dr. Riaz Reply

 January 8, 2021
Your SGOT/SGPT is raised, showing liver cell necrosis. Please rule out alcohol and pain killer therapy.
paresh Reply
 January 11, 2021
my SGPT is 84 is it to much high ?
Dr. Riaz Reply

 January 11, 2021
I can say this is raised. You should do a complete liver function test. I will suggest repeating your test after 2 to 3 months.
Sayanika Reply
 January 29, 2021
My sister’s SGOT is 31.5 and SGPT is 39.6. Other parameters in liver function test is normal. She is 23 yrs old. Is it serious?
Isha Reply
 January 29, 2021
My sisters SGOT is 31.5 and SGPT is 39.6. Other parameters in liver function test is normal. She is 23 yrs old. Is it serious?
Dr. Riaz Reply

 January 29, 2021
These levels are in the normal range; I don’t think is serious. If you are very conscious, repeat liver function tests (LFT) after 2 to 3 months.
BHIZHI Reply
 February 5, 2021
hi! my SGPT US 61.45
IM 31 YEARS OLD.
Dr. Riaz Reply

SGPT is slightly raised. You should have done a complete liver function test (LFT).
Sukanya Y Reply
Sir,
BILIRUBIN-TOTAL 0.30 mg/dL 0.20 – 1.20 Diazonium salt
BILIRUBIN-DIRECT 0.10 mg/dL 0.0-0.3 Spectrophotometric
BILIRUBIN-INDIRECT 0.20 mg/dL 0.0-1.10 Direct measure
ALKALINE PHOSPHATASE 99.00 U/L 38-126 PNP
AST/SGOT 29.0 U/L 17-59 UV with P-5-P
ALT/SGPT 15.0 U/L <35.0 UV with P-5-P
AST:ALT RATIO 1.93 Ratio Upto 1.3 Calculated
PROTEIN, TOTAL 6.80 g/dL 6.3-8.2 Biuret
ALBUMIN 4.10 g/dL 3.5 – 5.0 Bromocresol Green
GLOBULIN 2.70 g/dL 2.0-3.5 Calculated
A/G RATIO 1.52 0.8-1.2 Calculated
AST/ALT ratio and A/G ratio are not normal as per the above. Kindly analyse and advise.
Dr. Riaz Reply

Your LFT values are normal. I may not give importance to calculated values unless the values were abnormal.
ANAND UNNIKRISHNAN Reply

FBS 93
HDL 52
LDL 129
VLDL 21
BILIRUBIN 105
SGOT 80
SGPT 92
Kindly analyse and advise
Dr. Riaz Reply

FBS, HDL, VLDL are in the normal range. LDL can be decreased more. Your Liver function tests are abnormal. You must consult a hepatologist.
ove Reply
May 17, 2021
gpt- 47
got- 85
atio- 1.5
lirubin- 0.4
Riaz Reply
ay 18, 2021
r SGPT and SGOT are mildly raised. Please get detailed liver function tests and viral hepatitis profile (HBV, HCV). I hope you are not taking painkillers or alco
ny other drugs?
KAMRAN FAROOQ BHAT Reply

My sgot is 51
Sgpt 61
Billirubin 1.8
Blood sugar level 87
TSH 7.5
Ultra sound shows mild fatty liver.
What is your advice?
I feel fatigue
Dr. Riaz Reply

Your SGOT and SGPT are slightly above the normal value. But your TSH (If it is mU/L) level is too high, indicating hypothyroidism. Hypothyroidism can lead
to feelings of fatigue. Please read the following link and have a complete workup of thyroid functions.
https://www.labpedia.net/thyroid-part-2-thyroid-stimulating-hormone-tsh-thyrotropin/ (https://www.labpedia.net/thyroid-part-2-thyroid-stimulating-
hormone-tsh-thyrotropin/)
JP Reply
 March 1, 2021
SGPT – 102
SGOT – 6
Please advise
JP Reply
 March 1, 2021
SGPT – 102
SGOT – 6
Please advise
Dr. Riaz Reply

 March 1, 2021
SGPT represents a problem in the liver, and SGOT should also need to be raised. This is an unusual picture. I will advise repeating complete liver function
tests and viral hepatitis markers as well.
Mir Marri Reply

 March 4, 2021
Dr sb i have got my test reports. My sgpt is 139 & Hbv pcr is 892. How is the result dr sb. Waiting for ur kind answer.
Dr. Riaz Reply

 March 4, 2021
SGPT 139 is increased. HBV PCR value needs their normal range. It would be best if you had a physician consultation for the treatment.
Hema Malini Reply

 March 7, 2021
TEST NAME TECHNOLOGY VALUE UNITS NORMAL RANGE
ALKALINE PHOSPHATASE PHOTOMETRY 61.8 U/L 45 – 129
BILIRUBIN – TOTAL PHOTOMETRY 0.78 mg/dl 0.3-1.2
BILIRUBIN -DIRECT PHOTOMETRY 0.24 mg/dl < 0.3
BILIRUBIN (INDIRECT) CALCULATED 0.54 mg/dl 0-0.9
GAMMA GLUTAMYL TRANSFERASE (GGT) PHOTOMETRY 19.1 U/l < 38
ASPARTATE AMINOTRANSFERASE (SGOT ) PHOTOMETRY 34.4 U/l < 31
ALANINE TRANSAMINASE (SGPT) PHOTOMETRY 44.4 U/l < 34
PROTEIN – TOTAL PHOTOMETRY 7.1 gm/dl 5.7-8.2
ALBUMIN – SERUM PHOTOMETRY 4.2 gm/dl 3.2-4.8
SERUM ALB/GLOBULIN RATIO CALCULATED 1.45 Ratio 0.9 – 2
SERUM GLOBULIN PHOTOMETRY 2.9 gm/dL 2.5-3.4
Please correlate with clinical conditions.
Method :
ALKP – MODIFIED IFCC METHOD
BILT – VANADATE OXIDATION
BILD – VANADATE OXIDATION
BILI – DERIVED FROM SERUM TOTAL AND DIRECT BILIRUBIN VALUES
GGT – MODIFIED IFCC METHOD
SGOT – IFCC* WITHOUT PYRIDOXAL PHOSPHATE ACTIVATION
SGPT – IFCC* WITHOUT PYRIDOXAL PHOSPHATE ACTIVATION
PROT – BIURET METHOD
SALB – ALBUMIN BCG¹METHOD (COLORIMETRIC ASSAY ENDPOINT)
A/GR – DERIVED FROM SERUM ALBUMIN AND PROTEIN VALUES
SEGB – DERIVED FROM SERUM ALBUMIN AND PROTEIN VALUES
Hi Dr. Riaz, Am i suffering from anything serious? Please advice. Thanks
Dr. Riaz Reply

 March 7, 2021
Only your SGOT and SGPT are mildly raised. Rest all tests are normal. I will advise eat more fruits and repeat only these two tests after 2 to 3 months.
Hema Malini Reply

 March 7, 2021
Does low uric acid in plasma or serum, an indication of any kidney disorder?
Dr. Riaz Reply

 March 8, 2021
You have not told how low is the blood uric acid level. Please read the following link, and this may be helpful for you.
https://www.labpedia.net/uric-acid-level-blood-uric-acid/ (https://www.labpedia.net/uric-acid-level-blood-uric-acid/)
Narendra Shekhar Reply

 March 22, 2021
Sgpt -132
Sgot – 98
Alkaline phosphate -242
Bilirubin – 2.1
Dr. Riaz Reply

 March 22, 2021
Your LFT is abnormal and needs a consultation by the physicians.
maria rahman Reply

 March 24, 2021
my sgpt (alt)is 60u/l and sgot (als) is 28 is it normal?
Maria Rhman Reply

 March 24, 2021
my age is 18 my sgpt(alt)is 60u/l and sgot(ast)is 28 is it risky?
Dr. Riaz Reply

 March 24, 2021
SGPT is slightly raised, but SGOT is normal. Please repeat both tests after one month. Take more fruits during this period. Avoid aspirin.
bon Reply
 March 31, 2021
Sgot is 33.9 and SGPT is 46.2
Dr. Riaz Reply

 March 31, 2021
SGOT looks normal and SGPT slightly above normal. My suggestion is to repeat the LFT (SGPT) after one month.
Sagar patil Reply

 March 31, 2021
Hello sir
My wifes sgpt 34 and sgot is 42.she is 7 months preganant.. Also she is taki g aspirin as per doctors advice..is thia range is normal?
Also the d dimer is 841..
Dr. Riaz Reply

 April 1, 2021
These values are normal. Because the aspirin may increase SGOT, when she stops aspirin, I hope SGOT will also be below 40. Give her more fruits that may
help her.
agar Reply
April 1, 2021
What about d dimer sir..
Riaz Reply
ril 1, 2021
se see the following link for D-dimer.
s://www.labpedia.net/d-dimer-test-fragment-d-dimer/ (https://www.labpedia.net/d-dimer-test-fragment-d-dimer/)
raj
mber 1, 2022
ctor
Years Male Affected with Jaundice and Taken the below test report on 23rd October and met a General Doctor . He advised to take Liv 52 Tablet for 15 days(
in a day) . I am not facing any Pain apart from lighter body tired. Kindly suggest me what to do next sir?
port taken on 23.10.22 :
FUNCTION TEST with GGT
M G G T 210.5 U/L
M SGOT 900 U/L
M SGPT 1549 U/L
M BILIRUBIN TOTAL :6.71 mg/dl
M BILIRUBIN DIRECT: 5.23 mg/dl SERUM BILIRUBIN INDIRECT : 1.48 mg/dl
M ( Hepatitis B ) Non reactive 0.36
M ANTI HCV (C VIRUS) Nonreactive (0.09)
ggest Doctor ,Can I continue the Liv 52 tablet another one week?
az
mber 1, 2022
Liver function tests are abnormal. It is good that HBV and HCV are negative. To see the effect of the drug you are taking, please repeat LFT after two weeks. If
roved, you can continue the medications as your physician advises.
agar patil Reply

April 1, 2021
What about d dimer sir?
Jay Reply
 April 12, 2021
my SGPT is 87.77 and my SGOT is 92.47 what should i do? thank u
Dr. Riaz Reply

 April 12, 2021
Your LFT is abnormal; you need further workup like complete LFT with gamma-GT. Ultrasound of abdomen. If you are using alcohol, first quit and recheck
LFT after one month.
If no improvement, then consult a hepatologist or gastroenterologist.
RAHUL YADAV Reply

 April 15, 2021
Sir my LFT test is
SPGT LEVEL 199
SOGT LEVEL 65
BILUBRIN LEVEL 0.80
IS IT IN DANGEROUS LEVEL
Dr. Riaz Reply

 April 15, 2021
Your liver function tests (LFT) are abnormal. No doubt, bilirubin is normal. This needs to rule out liver cell necrosis like alcohol intake, viral hepatitis, and
some drug use.
It would be best if you had thorough work up to find the cause of abnormal LFT.
Robin kumar Reply

 April 16, 2021
HDL / LDL Cholesterol Ratio
Value: 0.50 ratio
Normal Range:-ratio – -ratio
SGOT/AST
Value: 54.00 U/L
Normal Range:0U/L – 50U/L
SGPT/ALT
Value: 92.20 U/L
GGTP (Gamma GT)

Value: 71.00 U/L
SGOT/SGPT Ratio
Value: 0.59 ratio
Normal Range:0.7ratio – 1.4ratio
Proteins, Serum
Value: 7.26 g/dL
Normal Range:6.6g/dL – 8.3g/dL
Albumin, Serum
Value: 4.65 g/dL
Normal Range:3.5g/dL – 5.2g/dL
A/G Ratio
Value: 1.78 ratio
Normal Range:1.2ratio – 2.2ratio
Bilirubin Total, Serum

Value: 1.07 mg/dL
Normal Range:0.3mg/dL – 1.2mg/dL
Bilirubin Direct, Serum

Value: 0.20 mg/dL
Bilirubin- Indirect, serum

Value: 0.87 mg/dL
Alkaline Phosphatase, Serum
Value: 109.00 U/L
please suggest. Is it critical?
Dr. Riaz Reply

 April 16, 2021
Your SGOT, SGPT. and Gamma GT is raised. It would help if you had further workup to rule out any disease of the liver. Please consult the physician for
further workup.
George Reply
 April 30, 2021
Hi I’m George ALT/SGPT 14.08 U/L 14.08 ukat/L, please help me understand my findings. Thank you and Godbless
Dr. Riaz Reply

 April 30, 2021
SGPT 14.08 U/L is in the normal range, and no need to worry.
George Reply
 May 1, 2021
Thank you so much Dr. Riaz
You ease my worries. Thank you for helping me.
More power and Godbless
nasir Reply
 May 8, 2021
im 35 year old my last week report about sgpt leve is 77
and bilirubin leve is 0.37
every week i did my test and some time result shown sgpt level 80 then 60 then 65 then 35 then 55 then 89 then 77 and bilirubin leve is always normal.
whats i do is this thing is dangerous or not
Dr. Riaz Reply

 May 8, 2021
SGPT level fluctuations mean that some minor injury in the liver, the causes may be viral hepatitis C, alcohol intake, some pain killer medications. You
have to rule out these possibilities.
nasir Reply
 May 9, 2021
Thanks for the replay dear , few month ago i was sick and i used antibiotics medicines for 20days, after that is issue is rise ( increase of sgpt) i don’t use
alcohol..
i used using the Estar tablet 10mg twice in a week, is this tablet is harmful in high SGPT or not please answer on this,,, and today on 5//9/2021 i repeat
my sgpt test that was 61 befor is that was 77 in last week,,, i try to control this on proper diets,, actually im food lover and i like to eat fish and meals
but now a days im on diet,, is this problem can be handle on diet or i need to visit doctor
thanks again for your replay to my message Doctor
Dr. Riaz Reply

 May 9, 2021
Your LFT is definitely abnormal. I will suggest consulting some hepatologist or gastroenterologist.
nasir Reply
 May 10, 2021
Thanks
yes i have ulcer problem from last 7 year …i just want to know that ,can i use Estar tablet 10mg , because if i dont use this tablet then i feel bad
Dr. Riaz Reply

 May 10, 2021
I think you can use Estar. For more details, see this link.
https://www.webmd.com/drugs/2/drug-10716/estar-topical/details#:~:text=This%20medication%20is%20used%20on,the%20growth%20of%20skin%20cells
(https://www.webmd.com/drugs/2/drug-10716/estar-
topical/details#:~:text=This%20medication%20is%20used%20on,the%20growth%20of%20skin%20cells).
nasir Reply
 May 10, 2021
I will see the link sir .. and thanks for your help I will remember you in my prayers
Natassa Reply
 May 19, 2021
SGPT/ALT is 9 and SGOT/AST is 11. The SGPT/ALT is very low. What does it mean? I am 50.
Dr. Riaz Reply

 May 19, 2021
I will say that these tests are normal and no need to worry.
chaminda Reply
 May 19, 2021
my SGOT 36.0 U/L AND SGPT 42.6 U/L Please advice
Dr. Riaz Reply

 May 19, 2021
SGOT is normal, and SGPT is boerder-line. Please take more fruits and repeat the liver function test after one month and then let me know the result.
Avinash Reply
 May 22, 2021
Sgot 43
Sgpt 50
Should I worry?
Age 25
Dr. Riaz Reply

 May 22, 2021
Your SGOT/SGPT are mildly raised. You need to worry and find the cause like viral hepatitis, and some drugs may increase. Better consult a physician to
find the cause.
M Singh Reply
 May 30, 2021
Sgot 47
Sgpt 88
S Bilurubin total 1.0
ALP 170
RFT all normal values
Blood sugar 70
Should I worry?
Age 36
Was taking 2-3 drinks daily from last 20-25 days
Dr. Riaz Reply

 May 31, 2021
I think your SGOT/SGPT is raised due to alcohol intake. I will suggest stopping alcohol for at least 2 to 3 months till these enzymes are normal. Then you can
take off and on alcohol but not regularly. Otherwise, you will develop cirrhosis of the liver, which ultimately leads to liver failure.
rivaldo Reply
 June 12, 2021
Dear Dr. Diaz
I wonder why AST is specifically more elevated in case of periportal necrosis in Preeclampsia ?
Best, regards
Rivaldo
Dr. Riaz Reply

 June 12, 2021
You may see hypertension, proteinuria, oliguria, pulmonary edema, thrombocytopenia, and elevated transaminase level in preeclampsia. I think these are
the complications of preeclampsia.
Maria Reply
 July 5, 2021
my sister’s sgpt test’ report says that she has 186 U/L. is it too much? what we can do for her? she is only 9 years old.
Dr. Riaz Reply

 July 14, 2021
What is SGOT, total bilirubin and alkaline phosphatse? Please also ask for viral markers (HBV. HCV).
Yuvaraj Reply
 July 28, 2021
BLOOD – SUGAR(F)- 85 msg/dl
BLOOD – SUGAR(PP) at 1 1/1hrs – 95 msg/dl
LIVER PROFILE:
BILIRUBIN(TOTAL) – 1.1 mg/dl
BILIRUBIN(DIRECT)- 0.4 mg/dl
BILIRUBIN(INDIRECT)- 0.7 mg/dl
SGOT- 93 IU/L
SGPT – 91 IU/L
SERUM ALK PHOSPHATASE
IFCC – 88 U/L
PROTEIN
(Serum/BCP) : 7.5 g/dl
ALBUMIN : 4.9 g/dl
GLOBULINS : 2.6
A/G RATIO : 1.8
(Serum/ Arsenazo III)
Dr. Riaz Reply

 July 29, 2021
I don’t know your age. All your parameters are normal except SGOT/SGPT, Which indicates liver cell injury. I hope you are not taking alcohol. Would you
please check your viral hepatitis profile (HBV, HCV)?
uvaraj Reply
July 29, 2021
6 age sir
uvaraj Reply
July 29, 2021
y age 36, I consume alcohol daily, What should I do Sir ?
Uvaraj Reply
 July 29, 2021
BLOOD – SUGAR(F)- 85 msg/dl
BLOOD – SUGAR(PP) at 1 1/1hrs – 95 msg/dl
LIVER PROFILE:
BILIRUBIN(TOTAL) – 1.1 mg/dl
BILIRUBIN(DIRECT)- 0.4 mg/dl
BILIRUBIN(INDIRECT)- 0.7 mg/dl
SGOT- 93 IU/L
SGPT – 91 IU/L
SERUM ALK PHOSPHATASE
IFCC – 88 U/L
PROTEIN
(Serum/BCP ) : 7.5 g/dl
ALBUMIN : 4.9 g/dl
GLOBULINS : 2.6
A/G RATIO : 1.8
(Serum/ Arsenazo III)
Pratiksha Kumari Reply

 July 31, 2021
I’m 26 female and my SGPT is 43.4 rest everything is normal
Also creatinine serum is 0.86

Do I need to worry and wha further tests should be done?
Dr. Riaz Reply

 July 31, 2021
I don’t think you need to worry. Just repeat SGPT after 2 to 3 months.
Rahul Reply
 August 7, 2021
Sgpt-1200 u/ml
Sgot-400 u/ml
Billirubin is 4.2
My age is 49 .. What to do?
Dr. Riaz Reply

 August 7, 2021
Your liver function tests are abnormal, and you must have clinical jaundice. You should check your viral profile like HBV, HCV, and HAV.
Rahul Reply
 August 7, 2021
Doctor, sgpt and sgot is in u/lit
Sia Reply
 August 11, 2021
my sgpt is 31u/l and i’m a 20 yr old female . is it high?
Dr. Riaz Reply

 August 11, 2021
What about SGOT?. But this is in the normal range.
Sia Reply
 August 11, 2021
MY DR. JUST ASKED ME TO GET THAT SGPT TEST DONE ALONG WITH THYRIOD. WHEN MY SGPT RESULTS WERE OUT THEY SAID IN FEMALES IT HAS
TO BE 21U/L AND BELOW AND ACCORDINGLY MY LEVELS ARE HIGH. PRETTY CONFUSED AS MY REPORT INDICATES NORMAL WHERE AS DR. SAYS
ITS NOT, AND THEN THEY ASKED ME TO DO FIBRO SCAN SAYING I MIGHT HAVE A FATTY LIVER AND AFTER DOING THAT MY RESULT WAS NORMAL.
Deepti Reply
 August 21, 2021
My SGOT is 47 and SGPT is 16. I am 22 years old female. I have lost my appetite and doesn’t feel hungry at all.
Dr. Riaz Reply

 August 21, 2021
SGOT is the upper limit of normal. I will advise you to repeat the complete liver function test and ESR after at least 1 to 2 months. Meanwhile, avoid aspirin
intake. Are you taking any other medications?
asroor Reply
May 20, 2022
r my LFT(6 para) test is
erum bilirubin is 6.5 total
erum bilirubin is 4.5 direct
erum bilirubin is 2.0 indirect
gpt(AlT) is 1957
lkaline phosphate is 259
amma GT is 44
r it can be normal my niece age is 18 years
Riaz Reply
ay 20, 2022
se liver function tests are abnormal, indicating hepatitis. Have you done viral profiles like HBV and HCV? She needs consultation to find the cause of jaundic
GDS Reply
Hello Sir,
I am GDS, 45, Male. My SGOT is 40, SGPT is 55, GGTP is 80. Cholesterol Total Serum is 239, Glucose Fasting is 154. I do not take alcohol. What is the cause
and what to prevent. Please guide.
JS Reply
Hello Sir,
I am JS, 42, Female. My SGOT is 35, SGPT is 73, GGTP is 57. Cholesterol Total Serum is 176, Glucose Fasting is 111. I do not take alcohol. What is the cause
JS Reply
Hello Sir,
I am JS, 42, Female. My SGOT is 35, SGPT is 73, GGTP is 57. Cholesterol Total Serum is 176, Glucose Fasting is 111. I do not take alcohol. What is the cause
Dr. Riaz Reply

Your SGPT is raised, which indicates liver cell injury.
Fasting glucose level is in the normal range. Cholesterol is also not high.
You need a thorough workup for the liver. I hope you are not taking any painkillers?
GDS Reply
Hello Sir,
I am GDS, 45, Male. My SGOT is 40, SGPT is 55, GGTP is 80. Cholesterol Total Serum is 239, Glucose Fasting is 154. I do not take alcohol. What is the cause
and what to prevent. Please guide me.
Regards
Dr. Riaz Reply

Your fasting glucose favor diabetes mellitus, so you should rule out diabetes mellitus. Please check fasting glucose level at least three times, and if still, it is
more than 126 mg/dL, then it is diabetes mellitus.
Your cholesterol level is raised.
It would be best if you had a physical checkup to rule out Diabetes mellitus.
Also, it would be best if you had diet control for cholesterol.
NILESH BHASKAR NAIK Reply

Hi DOCTOR, I RECENTLY DID MY LFT AND RESULTS ARE SGOT 56.4, SGPT 54.7, DIRECT AND INDIRECT BILLIRUBIN SKIGHTLY INCREASED,
I HAVE GILBERT’S SYNDROME ALSO I DID MY SONOGRAPHY, EVERYTHING WAS NORMAL. EXCEPT SLUDGE IN GALL BLADDER, WHAT SHOULD I DO?
Dr. Riaz Reply

This is a benign condition and there is no specific treatment. Gilbert’s syndrome is a life-long disorder.
You have to avoid some of the drugs. here are a few of those.
1. Gemfibrozil, for lowering cholesterol.
2. Statins, also used for reducing cholesterol, when taken with gemfibrozil.
Please see this links:
https://labpedia.net/gilberts-syndrome-diagnosis/ (https://labpedia.net/gilberts-syndrome-diagnosis/)
Jugitasharma Reply
Sir I am 28 years old female my SGPT IS 49
Alkaline phosphate is 102, GGTP is 15 are my reports normal sir??
Dr. Riaz Reply

These values are normal except for SGPT, which is the normal upper range. You can repeat SGPT, SGOT after 2 to 3 months.
Sobia Reply
My sgpt is 165 I am 34 years old
Dr. Riaz Reply

Your SGPT is raised, indicating liver cell injury. Would you mind letting me know complete liver function tests and Ultrasound abdomen report?
Sussie Reply
Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.
VSG: 22 mm/hr
Liver Profile:
Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L
Sussie Reply
Liver Profile:
Globulin: 2.8 gr/dl
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L
Sussie Reply
Globulin: 2.8 gr/dl
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L
Dr. Riaz Reply

Your tests are normal, except GGT and SGPT are normal upper range. This may be due to pain killer intake or any other medicines. I will suggest you,
please repeat after 2 to 3 months only GGT, SGOT, and SGPT.
Sussie Reply

Globulin: 2.8 gr/dl
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L
Rashmi Reply
 October 5, 2021
My CBC report:
Platelete count is 89000
Lymphocytes 51%
MCH 25.88%
LFT test Reports

Only SGPT is raised upto 38 IU/L all other Reports are normal… Plz suggest what to do next
Dr. Riaz Reply

 October 5, 2021
Platelets are low; lymphocytes are more than the normal range. SGPT and MCH is normal. This patient needs workup. Why are platelets low?
Ankit Kumar Reply

 October 21, 2021
My LFT report:- Impression (Grade 1 fatty liver)
SGOT:- 35 IU/L
SGPT:- 71IU/L
Bilirubin Total:- 2.6 mg/dl
Bilirubin Direct:- 1.3 mg/dl
Bilirubin indirect:- 1.3mg/dl
In every test, I have noticed my bilirubin level has been elevated what is the reason behind it. I have consulted a few doctors but they have not been
able to find the reason behind it.
Dr. Riaz Reply

 October 22, 2021
Your case fits into Dubin-johnson syndrome, but your SGPT level does not favor it.
https://labpedia.net/dubin-johnson-syndrome-diagnosis/ (https://labpedia.net/dubin-johnson-syndrome-diagnosis/)
See above link.
I hope you are not a drinker. Bilirubin above 2 mg/dL will show yellowness of the eyes. Would you please check your hemoglobin, viral hepatitis profile,
and urine examination?
Then let me know the results.
Manish Reply
 October 29, 2021
My complete report as follows
LIVER & KIDNEY PANEL, SERUM
(Reflectance Photometry,Direct ISE)
Bilirubin Total 0.60 mg/dL 0.30 – 1.20
Bilirubin Direct 0.11 mg/dL <0.30
Bilirubin Indirect 0.49 mg/dL <1.10
AST (SGOT) 37 U/L <50
ALT (SGPT) 80 U/L <50
GGTP 71 U/L <55
Alkaline Phosphatase (ALP) 108 U/L 30 – 120
Total Protein 6.73 g/dL 6.40 – 8.30
Albumin 4.20 g/dL 3.50 – 5.20
A : G Ratio 1.66 0.90 – 2.00
Urea 21.73 mg/dL 17.00 – 43.00
Creatinine 0.82 mg/dL 0.67 – 1.17
Uric Acid 7.43 mg/dL 3.50 – 7.20
Calcium, Total 8.89 mg/dL 8.80 – 10.60
Phosphorus 3.48 mg/dL 2.40 – 4.40
Sodium 138.70 mEq/L 136.00 – 146.00
Potassium 4.11 mEq/L 3.50 – 5.10
Chloride 104.14 mEq/L 101.00 – 109.00
These test has done on morning and last night I had alcohol… does it may refect in test
Kindly tell me what to do
Dr. Riaz Reply

 October 29, 2021
Definitely, alcohol will affect SGOt/SGPT and GGT levels. Your cholesterol level is also normal upper limit (borderline case). You have not mentioned the
HDL.
LDL and VLDL are atherogenic and predispose to heart diseases. I will suggest quitting alcohol, and it will damage the liver.
anish Reply
October 30, 2021
est Name Results Units Bio. Ref. Interval
PID SCREEN, SERUM
pectrophotometry)
holesterol, Total 216.83 mg/dL <200.00
riglycerides 137.73 mg/dL 40.00
DL Cholesterol, Calculated 147.17 mg/dL <100.00
LDL Cholesterol,Calculated 27.55 mg/dL <30.00
on-HDL Cholesterol 175 mg/dL <130
Manish Reply
 October 29, 2021
In addition
LIPID SCREEN, SERUM
(Spectrophotometry)
Cholesterol, Total 216.83 mg/dL <200.00
Triglycerides 137.73 mg/dL 40.00
LDL Cholesterol, Calculated 147.17 mg/dL <100.00
VLDL Cholesterol,Calculated 27.55 mg/dL <30.00
Non-HDL Cholesterol 175 mg/dL <130
Manish Reply
 October 30, 2021
Test Name Results Units Bio. Ref. Interval
LIPID SCREEN, SERUM
(Spectrophotometry)
Cholesterol, Total 216.83 mg/dL <200.00
Triglycerides 137.73 mg/dL 40.00
LDL Cholesterol, Calculated 147.17 mg/dL <100.00
VLDL Cholesterol,Calculated 27.55 mg/dL <30.00
Non-HDL Cholesterol 175 mg/dL <130
Nawaz Shah Reply

My sisters SGPT level is 2080 and 0-35 is recommended in report. How bad it is??
Bilirubin 2.6
RBC count 5.35
Any suggestions
Dr. Riaz Reply

SGPT level and bilirubin are raised. There is liver cell injury. Would you please advise liver functions test and viral hepatitis profiles?
Himanshu Reply
Sgpt 46
Direct bilirubin 0.6
Others normal
Should I worry or continue eating everything?
I’m not alcoholic.
I have gastritis for 2 weeks also
Dr. Riaz Reply

Bilirubin level is normal. For gastritis, you need treatment. At least avoid spices.
Himanshu Reply
Can gastritis be cured without medicines by dietary changes sir?
John Reply
Hi doc my sgpt is 287 but other than that all my test are normal
My doc ask me to undergo liver ultrasound and these is what it says:
The liver is normal in size with a span of 13.7cm. Its border is smootu but there is marke increase in the parenchymal echogenicity and the
intrahepatic veins not visible. There is no focal lesion nor calcification
The common bile duct and intrahepatic ducts are not dilated
John Reply
Hi doc, my sgpt level is 287, so my doctor said to undergo liver ultra sound and this is my ultra sound says
The liver is normal in size with a span of 13.7cm. Its border is smootu but there is marke increase in the parenchymal echogenicity and the
intrahepatic veins not visible. There is no focal lesion nor calcification
The common bile duct and intrahepatic ducts are not dilated
And another thing doc, i read in the internet that they need 5ml of blood for sgpt test
The clinic i went only got 1ml of my blood
Dr. Riaz Reply

SGPT is raised, you need a complete liver function test including gamma GT. 5 mL blood is ideal, but someone may get enough serum from one mL. Your
SGPT indicates liver cell injury.
John Reply
Thank u doc, another thing doc
All my test are normal, only my sgpt is high
Thanks again doc.
Taxia Reply
Is SGPT 56, SGOT 29 normal? Took flagyl and librax for some days.
THank you in advance (man)
Dr. Riaz Reply

SGPT is raised (abnormal), but SGOT is in the normal range. SGPT indicates liver cell injury. When SGPT is raised, there should be a mild increase in the
SGOT, which is not in your case. Better check both parameters after one month.
Mehedi hasan Reply

My name is Mehedi hasan. My test result from LABAID
HBsAg=Positive sample OD >10000 Cut-Off OD 1.0
Bilirubin=1.1 mg/dl
ALT(SGPT)=51 U/L
AST(SGOT)= 32 U/L
HBeAg= Negative
Anti-HCV= Negative
Anti-HBe= Positive sample OD 400 Cut-Off OD 100
Dr. Riaz Reply

These findings of HBsAg and HBeAg indicate chronicity. Your SGPT is mildly raised, but SGOT is normal. I will suggest keeping an eye on liver function tests
or getting the treatment for the hepatitis B virus.
Emarshana Reply
Usually both ast and alt are high in hepatic metastasis?
Dr. Riaz Reply

In metastatic, infiltrate of carcinoma depends upon the involvement of the liver area. There may be raised AST/ALT and alkaline phosphatase levels.
Anil Kumar Reply

Sgot – 43 and Sgpt – 48 my age is 36 I need to consult doctor.
Anil Kumar Telluri Reply

Sgot – 43 and Sgpt – 48 my age is 36. Could I need to consult doctor.
Dr. Riaz Reply

You need to repeat complete liver function tests after 2 to 3 months, and then let me know the results.
O pk Reply
Bilirubin(total) – 0.59 mg/dl
Bilirubin(direct) – 0.15 mg/dl
Bilirubin (indirect) – 0.44 mg/dl
Sgot -52 iu/l
Sgpt – 135 iu/l
Alkaline phosphatase – 168 u/l
Total protein – 7.6 gm/dl
Albumin – 5.5 gm/dl
Globulin – 3.1 gm/dl
A/G ratio – 1.5
Ggt – 34 iu/l
Age – 22 , No smoke and drinking.
Pain in upper abdomen liver side
Emergency?
Dr. Riaz Reply

Your SGOT and SGPT are raised, indicating liver cell injury. Would you please rule out any use of drugs? Also, check your viral profile (HBV, HCV).
pk Reply
December 2, 2021
o drug
Vishal Thakur Reply

Liver Function Test (LFT)
Serum Bilirubin, (Total)
Method: Diazo
1.06 mg/dl 0.2-1.2
Serum Bilirubin, (Direct)
Method: Diazo
0.34 mg/dl 0.0 – 0.5
Serum Bilirubin, (Indirect)
Method: Calculated
0.72 mg/dl 0.0 – 0.8
Aspartate Aminotransferase (AST/SGOT)
Method: IFCC
40.85 U/L 5 – 34
Alanine Aminotransferase (ALT/SGPT)
Method: IFCC
68.00 U/L 0 – 55
Alkaline Phosphatase (ALP)
Method: IFCC AMP Buffer
96.00 U/L 43 – 115
Gamma Glutamyl Transferase (GGT)
Method: IFCC
38.5 U/L 12-64
Serum Total Protein
Method: Biuret
8.22 g/dl 6.6 – 8.3
Serum Albumin
Method: Bromo Cresol Green(BCG)
5.01 g/dl 3.5 – 5.2
Serum Globulin
Method: Calculated
3.21 gm/dl 3.0 – 4.2
Albumin/Globulin Ratio
Method: Calculated
1.56 Ratio 1.2 – 2.5
SGOT/SGPT Ratio
Method: Calculated
0.60 Ratio 0.7 – 1.4
My age is 23. Is there anything need to worry.
Dr. Riaz Reply

Your SGOT and SGPT are mildly raised. Please repeat SGPT/SGOT after 2 to 3 months. Also, check your HBV and HCV status. I hope you are not taking any
medicines?.
ishal Thakur Reply

December 5, 2021
5 days ago i met with a road accident then i took a pain killer otherwise no medicines. For past 2 weeks i am doing only lunch and dinner and skipping
reakfast. can this may be the reason?
Vishal Thakur Reply

15 days ago i met with a road accident then i took a pain killer otherwise no medicines. For past 2 weeks i am doing only lunch and dinner and
skipping breakfast. can this may be the reason?
challa pavan Reply

hi…sir 5 day before sgpt test 45iu/l sgot 31iu/l but now today sgpt 576.8 sgot 509u/L I hv jaundice what happen sir….plz suggest
Dr. Riaz Reply

It means your liver function tests are abnormal. Would you please advise viral markers (HBV, HCV, and HAV)?
Bhavar Reply
My sgpt is 110 in liver function test rest is in normal range what it say
Dr. Riaz Reply

Raised SGPT indicates liver cell injury. It needs a thorough workup to find the cause.
ASHWANI Reply
MY SGOT IS 331 OR SGPT IS 171 PLS SOME ADVISE
Dr. Riaz Reply

SGOT/SGPT raised level indicates liver cell injury. You should have viral markers and have ultrasound abdomen. Please keep on checking the liver function
tests every three months at least.
vineet Reply
SGOT-39
SGPT-66
Drinks occassionally. Is it high? I have gilberts syndrome and little bit high cholestrol
Age-30
Dr. Riaz Reply

SGPT is raised, and it indicates liver cell injury. Can you check your gamma GT level? If it is raised, then avoid alcohol.
vineet Reply
Ultrasound abdomen is normal
Anurag Gautam Reply

Hello Doctor,
I went through with the routine checkup and Below are my reports.
Please advise.
HbA1c 5.7
LDL CHOLESTEROL – DIRECT 173
TOTAL CHOLESTEROL 239
HDL CHOLESTEROL – DIRECT 37
LDL / HDL RATIO 4.7
TC/ HDL CHOLESTEROL RATIO 6.5
BILIRUBIN – TOTAL 1.49
ASPARTATE AMINOTRANSFERASE (SGOT ) 207.9
ALANINE TRANSAMINASE (SGPT) 395.76
Dr. Riaz Reply

Your reports are not good. It looks you are not living a healthy life. Your HDL is low, good cholesterol, while LDL is high, which is bad cholesterol. Liver
enzymes are raised. Please consult a physician to find the cause of these abnormalities.
Ella Mae Reply

Hi Doc! My SGPT is 358.1 and alkaline is 135.7 Before My test , Im having really bad abdominal pain in the center . What to do ?
Dr. Riaz Reply

Your SGPT is raised while alkaline phosphatase is in a normal range. I will suggest complete liver function tests and viral markers. You have not mentioned
the age.
Chintu Reply
 January 3, 2022
Sir my sgot-22.7,sgpt-38, alkaline phospa te-58,total protein-7.83, total cholesterol-199,ldl-141,hdl-53, triglycerides-118, please advise
Dr. Riaz Reply

 January 3, 2022
You have not mentioned your age. Your lipid profile looks good. Only cholesterol is the upper limit.
Jeremy Reply
 January 4, 2022
39 year old male
SGOT-31U/L
SGPT-30 U/L
ALP- 97 IU/L
Albumin- 4.6 GM/ DL
Total Protein – 7.4 G/DL
Do you see any concerns?
Thank you
Jeremy Reply
 January 4, 2022
39 year old Male
SGOT-31U/L
SGPT-30 U/L
ALP- 97 IU/L
Albumin- 4.6 GM/ DL
Total Protein – 7.4 G/DL
Do you see any concerns?
Dr. Riaz Reply

 January 4, 2022
Congratulations, your LFT is normal.
pam Reply
 January 12, 2022
MY AST (SGOT) is 58
MY ALT (SGPT) is 115
I am 63 year old female
Dr. Riaz Reply

 January 12, 2022
Your liver functions are abnormal. What about total bilirubin?. I will suggest doing complete liver function tests. I hope you are not taking alcohol?. Your
enzymes indicate liver cell injury. It needs full workup and consultation with the physician.
Sarfraz khan Reply

 January 21, 2022
My sgpt is 124 sgot 165 and ggt 65
Is it serious sir ?
Dr. Riaz Reply

 January 21, 2022
Both enzymes are raised. Not good for your health. Please consult some gastroenterologist and have complete work up. Health is wealth.
Mr. Bhushan Reply

Hi Dr. Riaz,
I drink 3 times a week heavy (270ml in one sitting) from last 10 years. I have been reading on LFT and so did the test.
My SGOT is 38 (0<30) and SGPT is 95 (0<45) rest stuff are all under normal range.
Can you please advice me further diagnosis.
PS: I am healthy and fit and heavily cut on my drink from last few weeks (sitting once in a week 180-240 ml)
Dr. Riaz Reply

Raised SGPT level indicates liver cell injury. SGOT is not specific for liver cell injury as compared to SGPT. I suggest that you quit the alcohol and repeat the
liver function test after 3 months. Otherwise, you may develop liver cirrhosis.
Sayan ghosh Reply

Hii sir
My bilirubin total 1.42
Sgot 65.14
Sgpt 76.48
I am 21 y old
Dr. Riaz Reply

Your SGOT and SGPT are raised, indicating liver cell injury. I hope you are not taking alcohol?. If not then go for hepatic viral profile.
Biswarup Reply
Hi Doctor
6 months back I have done full body check up and I have found my Sgpt -150 ,sgot-72 then I did test for hepatitis B&C and it also came negative and
then I farther proceed with ultrasound and it came as grade 2 fatty liver and size of the liver was 17.2 .
By that time I was 30 ,hight 164 cm and weight 81 kg.
I controlled my food habits and did regular exercise and now it is showing after 6 months sgpt-72,sgot-48 and other parameters are ok.
How long it will take to come back to normal or any thing to concern and do I need to go for fibro scan
Dr. Riaz Reply

If liver cells are insulted by alcohol or anything else, it will take at least 3 months to regenerate. Also, try to take more fruits. In your case, it is 6 months,
and still, SGPT is raised, indicating liver cell injury. If it remains elevated, then consult a gastroenterologist (or hepatologist).
Biswarup Reply
Forgot to mention my weight is 62 now
Muhammad Imran Reply

My daughter is 2.5 years old today she felt pain in stomach when I done her sgpt it’s too high 450 now what I please guide me
Which doctor I need to consult .
Dr. Riaz Reply

You should have complete liver function tests (LFT) and an ultrasound abdomen. After workup, consult a pediatrician.
gyen Brefo Reply

September 28, 2022
ello dr I’m 35 my lft
bilirubin (total ) 9
bilirubin conjugated 1
Alkaline phosphatase 79
g-Glutamyl transferase 35
Alt. (Gpt). 122
ASt (Got). 55
total protein. 75
AlBUMIN. 43
ease comment
Riaz Reply
ptember 28, 2022
you sure the Total bilirubin is 9? Your SGOt/SGPT is raised, which favors liver cell damage. First, clarify the total bilirubin level. Please also check the viral
atitis profile (HBV, HCV).
n Brefo
mber 29, 2022
ease the range is 3.42 – 20.5 umol/l after the text the doctor advise is to stop alcohol and I have been taking livolin forte for three since the test
az
mber 29, 2022
Nikesh Reply
hi Dr Riaz,
Could you please comment on this.
Test Name Results Biological Reference

Interval Units Specimen Test Method
SGOT (AST) 32.15 < 35 U/L Serum IFCC without P5P
SGPT (ALT) 53.58 H < 45 U/L Serum IFCC without P5P
Gamma GT (GGT) 39.00 < 55 U/L Serum Enzymatic,Colorimetric
Assay
Uric Acid 7.95 H 3.5 – 7.2 mg/dL Serum Enzymatic Colorimetric
Method
Dr. Riaz Reply

In your lab tests, SGPT is slightly raised, and uric acid is also. You need to repeat SGPT/SGOT and uric acid after at least 1 to 3 months. If still raised, you will
need medicine for uric acid and a detailed workup for liver function.
ikesh Reply
February 25, 2022
hank you Doc. Appreciate so much
Saleem Reply
My wife is 37 weeks and 2 days pregnant. She had severe itching problem but now it’s resolved. LFT level on 14.02.2022 SGPT 226 ,SGOT 149, ALP 188
,GT 44 all others are in normal range. Fasting bile acid test (4.5 umol/l) with in normal range. no symptom of jiaundice. no other symptoms. HAV IgM
non reactive, HAV IGg reactive, anti HEV IGg and IgM non reactive, HbsAg non reactive and anti Hcv non reactive. PT 10 sec., APTT, 25 sec.,.INR 0.91.
Abdominal ultrasound showed liver has mildly increased echogenicity. After some dietry change and taking hepa merz syrup for 10 days. Repeat LFT
on 24.02.2022, the SGPT 77, SGOT 36 and ALP 176 all other are in normal range. Up till now, according to USG, dilivery is normal. I already consulted
two gynecologists, one,s advice is normal dilivery and other in favor of inducing dilivery at 38 week due risk of baby stillbirth. With these elevated
liver enzyme, can we go for normal dilivery or should induce dilivery at 38 weeks. Suggest some advice.
Dr. Riaz Reply

A gynecologist will give a better answer. Your lab reports say that she has hepatitis A infection and is in recovery. Hepatitis E infection is dangerous in
pregnancy, but that test is negative. I will suggest That you consult the third gynecologist and see what she says.
aleem Reply
February 24, 2022
hank you sir for your quick response. On the basis of these level of elevated enzyme, can we diagonse inertahepatic cholestasis or Acute fatty liver disease?
Riaz Reply
bruary 24, 2022
se see this link; this may be of help.
s://labpedia.net/alkaline-phosphatase-level-alp/ (https://labpedia.net/alkaline-phosphatase-level-alp/)
, you can see this link for acute fatty liver in pregnancy.
s://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538964/ (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538964/)
Loess Reply
Bonsoir Dr Riaz s’il vous plait j’ai besoin de explications :
Asat/got <40ul/L
Alat/gpt <37ul/L
ALTL 5.5u /L
ASTL 11.7u/L
Crej2 65.7umol/L
Urée 0,5-7,5mmol/L
Créatinine 40-120umol/L
Dr. Riaz Reply

GOT/GPT is normal, indicating liver function. Urea/Creatinine gives information about kidney function, which is also in the normal range.
Dr. Riaz Reply

Votre SGPT/SGOT, l’urée et la créatinine sont dans la plage normale. Ces tests parlent des fonctions hépatiques et rénales
Vj Reply
 March 2, 2022
SGPT 77
SGOT 30
Currently taking Isotretinoin. Is the mild increase in SGPT caused by Isoretinoin?
Vj Reply
 March 2, 2022
SGOT 30
SGPT 77
Currently taking Isotretinoin. Is the mild increase caused by Isotretinoin?
Dr. Riaz Reply

 March 2, 2022
This medicine is causing damage to your liver that leads to an increase in SGPT level. You can stop this medicine and repeat SGPT/SGOT after 1 to 2 months.
Charles Reply
 March 8, 2022
My test result shows SGPT(ALT) 115 IU/L
ALKALINE PHOSPHATASE 44.5 IU/L
GAMMA GT 51 IU/L
Please help interpret
Dr. Riaz Reply

 March 8, 2022
SGPT is raised, and Gamma GT is a very mild increase. It indicates liver cell injury. This may be due to some drugs, alcohol, or viral hepatitis. It would be
good to check your liver function tests (LFT) and hepatic viral profile.
ash Reply
 April 29, 2022
Why should you not use hemolyzed serum for ALT determination?
Dr. Riaz Reply

 April 29, 2022
Because RBCs are also the source of ALT.
Randy Baylon Reply

 May 18, 2022
I am 43 years old Male my
SGPT is 43
SGOT 23
Kindly advise if there is something to worry about? thank you very much…
Dr. Riaz Reply

 May 18, 2022
SGPT is the normal upper limit, and SGOT is normal. I will suggest repeating the test after one month and taking more fruits. At this stage no need to worry.
andy Reply
May 19, 2022
hank you very much Dr. Riyaz… more power to you…
Riaz Reply
ay 19, 2022
nks.
Mushtaq Reply
 May 20, 2022
Hello Dr. Sb,
I am 42 years and my SGPT is 154 . what does it indicate?
Dr. Riaz Reply

 May 20, 2022
SGPT is raised, indicating liver cell injury. This is not good for health. Please advise complete liver function test and viral markers (HBV, HCV). It would be
better to consult a physician.
Masroor Reply
 May 20, 2022
Sir my LFT(6 para) test is
Serum bilirubin is 6.5 total
Serum bilirubin is 4.5 direct
Serum bilirubin is 2.0 indirect
Sgpt(AlT) is 1957
Alkaline phosphate is 259
Gamma GT is 44
Sir it can be normal my niece age is 18 years
Sanjay Reply
 June 5, 2022
Hello Dr. Riaz ,
Below are my details is there a issue in liver and is it concerning ?
BILIRUBIN – TOTAL 0.6 mg/dl

BILIRUBIN -DIRECT 0.2 mg/dl
BILIRUBIN (INDIRECT) 0.4 mg/dl
ASPARTATE AMINOTRANSFERASE (SGOT ) 42 U/l
ALANINE TRANSAMINASE (SGPT) 90 U/l
ALKALINE PHOSPHATASE 76 U/L
GAMMA GLUTAMYL TRANSFERASE (GGT) 60 U/l
PROTEIN – TOTAL 7.1 gm/dl
ALBUMIN – SERUM 4.9 gm/dl
SERUM GLOBULIN 2.2 gm/dL
SERUM ALB/GLOBULIN RATIO 2.23
Sanjay Reply
 June 5, 2022
My age is 34
Dr. Riaz Reply

 June 5, 2022
SGPT and GGT are raised, indicating liver cell injury. I hope you are not taking any form of alcohol or pain killer?. You need to consult a physician.
Sanjay Reply
 June 5, 2022
My age is 34
Maris Reply
 June 8, 2022
I am 39 years old Female
My SGOT is 213.4 I am currently taking medications and supplements for my liver. After 2 weeks I took another lab exam for my SGOT and SGPT.
Right now my SGOT is 37.2 but my SGPT is high 54.4
Dr. Riaz Reply

 June 8, 2022
What was the SGPT the first time that you have not mentioned it? if you repeat the test after two weeks, SGPT may become normal by then?.
Sumi Reply
 June 11, 2022
Age-36
Female
SGPT -75
USG report normal
How can I decrease the SGPT level?
Is it serious?
Please suggest some foods help to reduce SGPT.
walking can help?
Sumi Reply
 June 11, 2022
I’m 36 years old female
SGPT 75
What I can do to decrease the sgpt?
Please suggest some foods help to reduce SGPT.
Can Walking help?
I took montelukast and levocetirizine every day.
Sumi Reply
 June 11, 2022
I’m 36 years old female
SGPT 75
USG report is normal
What I can do to decrease the sgpt?
Please suggest some food help to decrease the SGPT.
Can Walking help?
I took montelukast and levocetirizine every day.
Dr. Riaz Reply

 June 11, 2022
This SGPT may be due to medication. If you can afford it, stop this medication for one month and recheck the SGPT. As regards fruits, you can try
grapefruit.
Harman Reply
 June 14, 2022
Sir my age is 22. I do not consume alcohol
Total bilirubin=3.9
Direct bilirubin = 0.5
SGOT = 106
SGPT = 406
ALP P = 139
I consulted a doctor he advised that it is viral hepatitis with low virulence, no medication is needed. It will get good automatically. Do i need to worry
Dr. Riaz Reply

 June 14, 2022
Please get a viral hepatitis profile (HBV, HCV, HAV). No doubt there is an insult to the liver.
Dr. Riaz Reply

 June 14, 2022
Please advise viral hepatitis profile (HBV, HCV, HAV). Your LFT shows insult to the liver.
AK Reply
 June 14, 2022
Hi
My mother’s Sgot is 16 and Sgot is 6.30, though the values are within the normal range but the Sgot/Sgot ratio is 2.54. Is it a cause of concern? Please
advise
Dr. Riaz Reply

 June 14, 2022
When SGOT and SGPT are normal, then no need to see the ratio.
GJ Reply
 June 28, 2022
Sir, my SGPT – 98, SGOT- 70 All the other values in my liver function test are in normal range. Platelet count is 328 and fasting Glucose is 92. My Lipid
profile is also in normal range. Please advice next step
Dr. Riaz Reply

 June 28, 2022
Your SGOT/SGPT is raised, indicating liver cell injury. It would help if you had worked up, and I hope you are non-alcoholic. Please check your hepatitis
viral profile.
Abhinav Reply
 July 15, 2022
sir my mother is 42 and her LFT profile is
SGOT – 36 U/l
SGPT-43 U/l
ALKALINE PHOSPHATASE -81U/L
PROTEIN – TOTAL 7.30 g/dl
ALBUMIN – SERUM -4.2 g/dl
SERUM GLOBULIN -3.10 g/dL
and Lipid profile is –
Total cholesterol-192 mg/dl
Triglyceride- 169 mg/dl
HDL- 50 mg/dl
VLDL- 33.8 mg/dl
LDL- 108.2
Non-Hdl-142
LDL/HDL RATIO- 2.16 %
TOTAL/HDL RATIO – 3.84
please advice is there any thing to worry?
Dr. Riaz Reply

 July 15, 2022
There is no worry about these results only if you can control her cholesterol, triglycerides, and LDL. While HDL is good. Please manage the fat intake and
advise exercise.
Amar Reply
 July 16, 2022
Hi.
I did test 2 weeks ago for my job alplication. My sgpt is 51, and sgot 38.
So i need to get some medicine and retake the test. And now my sgpt is 34 and sgot same 38.
Can you please explain what happened to me 2 weeks ago? Im so curious
Thanks
Dr. Riaz Reply

 July 16, 2022
SGPT mild raise may be due to intake of pain killers even. So that might be due to some drugs effect. After a few days liver becomes normal.
Anna Reply
 August 1, 2022
Hi, I am 40 year old female. I have SGPT(ALT) 62.5 and SGOT (AST) 29.2. What should I do? How to lower down my SGPT?…Please advise…Thank you!
Loise Reply
 August 1, 2022
Hi, I am 40 year old female. I have SGPT(ALT) 62.5 and SGOT (AST) 29.2. What should I do? How to lower down my SGPT?…Please advise…Thank you!
Dr. Riaz Reply

 August 1, 2022
Raised SGPT indicates liver cell injury. Please check your viral profile (HBV, HCV, HAV). Are you taking any medicine or alcohol?
Grapefruit is considered good for the liver.
AARIKA Reply
 August 2, 2022
BILIRUBIN, TOTAL 1.01
BILIRUBIN CONJUGATED (DIRECT) 0.36
BILIRUBIN (INDIRECT) 0.65
ALANINE AMINOTRANSFERASE(ALT/SGPT) 63
ASPARTATE AMINOTRANSFERASE(AST/SGOT) 44
ALKALINE PHOSPHATASE 72
PROTEIN, TOTAL 7
ALBUMIN 4.6
A/G RATIO 1.92
Is this normal?
AARIKA Reply
 August 2, 2022
My age is 29, Do I need to worry?
Dr. Riaz Reply

 August 2, 2022
Your SGPT/SGOT level is mildly raised, indicating liver cell injury. It would be best if you found the cause of liver cell injury. Please check your viral hepatic
profile in case of non-alcoholics.
D.priyadarshani Reply
 August 5, 2022
Doctor, my husband’s LFT report as follows. Total protein 7.1g/dl
Albumin 4.5 g/dl
Globulin 2.6
Albumin globulin ratio 1.73
Bilirubin total 1.06
AST/SGOT 20.2
ALT/ SGPT 27.6
GGT 70.3
He is 40 years old and over weight. now he follows a diet plan. His ggt level seems to be higher than the reference range. Is this a big issue? Please
advise.
Dr. Riaz Reply

 August 5, 2022
GGT is not too high. It is an indicator of alcohol intake. I hope he is a non-smoker and non-alcoholic. You can repeat GGT after 1 to 2 months. Let him
reduce his weight. If possible, ask him to take more fruits.
.priyadarshani Reply
August 5, 2022
o doctor. He is non alcoholic and non smoker. But he has blood sugar, pressure and cholesterol. Take medications for that. All values are within reference
nge. Thank you for your advice.
Sandeep kaur Reply

 August 13, 2022
My father age 51 and sgot 115,,sgpt 104.
Dr. Riaz Reply

 August 13, 2022
SGOt and SGPT are raised, indicating liver cell injury. Please consult a physician to find out the cause of liver cell damage.
Duhanthi Reply
 August 23, 2022
Albumin 4.8 g/dl
Globulin 2.8
AST/SGOT 22.2
ALT/ SGPT 25
GGT 70.3 U/L
He is 40 years old,non alcoholic and over weight. Take medication for diabetes, pressure and cholesterol. All the report are normal now and he follows
a diet plan. Still His ggt level seems to be higher than the reference range. Is this a big issue? Please advise.
Duhanthi Reply
 August 23, 2022
Albumin 4.8 g/dl
Globulin 2.8
AST/SGOT 22.2
ALT/ SGPT 25
GGT 80.3 U/L
He is 40 years old,non alcoholic and over weight. Take medication for diabetes, pressure and cholesterol. All the report are normal now and he follows
a diet plan. Still His ggt level seems to be higher than the reference range. Is this a big issue? Please advise.
Dr. Riaz Reply

 August 23, 2022
GGT is a very sensitive test. This may be due to medications (drugs). Sometime medication like statin may increase GGT. I think to keep an eye on Liver
function tests.
Sintu Kumar Samanta Reply

My age is 40. I have done a complete liver function test. My SGOT is 38.60 and SGPT is 80.60. Rest parameters are in the normal range. My SGPT was
found normal 5 months back. In the meantime, I have taken some medicines for issues of osteoarthritis. Please advise
Dr. Riaz Reply

SGPT is raised, which might be due to medication for osteoarthritis. You need exercise to overcome osteoarthritis changes. Because 40 years is not the age
of osteoarthritis changes. Exercise, exercise, and exercise is the best medication for osteoarthritis changes.
Akshit Reply
if serum bilirubin total = 1.16 mg/dl ,serum bilirubin (direct) = 0.20 mg/dl & serum bilirubin (indirect) = 0.96 mg/dl
AST/SGOT=20.50 U/L ,ALT/SGPT=17.90 & ALP =136.00 U/L
AGE -19
PLEASE SUGGEST WHAT HAVE TO DO
Akshit Sharma Reply

Doctor, my son age 19 has LFT report as follows.
Serum Bilirubin (Total )=1.16 mg/dl
Serum Bilirubin (Direct )= 0.20 mg/dl
Serum Bilirubin (Indirect )-0.96 mg/dl
AST/SGOT =20.50 U/L
ALT/ SGPT =17.90 U/L
ALKALINE PHOSPHATASE ALP= 136.00 U/L
SIR His serum bilirubin (Indirect) and ALP level seems to be higher than the reference range. Is this a big issue? Please advise.
Dr. Riaz Reply

These liver function tests are in the normal range. Alkaline phosphatase normal values vary from lab to lab. Indirect bilirubin is not significantly high.
Total bilirubin is in the normal range. You can repeat liver function tests after 2 to 3 months.
Vivek Kumar Reply

Hello Doctor, My mother’s age is 45 yr, her lever test report as follows.
Serum Bilirubin Total 0.94 mg/dl
Serum Bilirubin Direct 0.63 mg/dl
Serum Bilirubin InDirect 0.31 mg/dl
SGPT 88.5 IU/L
SGOT 80.5 IU/L
Alkaline Phosphatase 69.3 U/L
Total Protein 6.96 gm/dl
Albumin 3.03 gm/dl
Globulin 3.93 gm/dl
Her mouth and tongue and throat is Blistered, unable to eat and drink and she is very weak ,weight about 38 kg, please suggest me what to do ? and is
there any things to worry.
Dr. Riaz Reply

Your mother’s SGOT and SGPT are raised, indicating chronic liver disease. Please check her viral hepatitis B and C. There is a possibility of viral hepatitis.
Simon Brown Reply

 October 12, 2022
Dear Dr. Riaz,
I really appreciate you helping out everyone. I am male 44 years old and have been doing 48 to 60 hours fasts to lose weight. I have lost around 10 kg,
however, I am still overweight. Otherwise I am not suffering from any problems that I know of.
I did a Liver profile and following are my readings:
Serum Total Bilirubin: 1.3

Serum Direct Bilirubin: 0.4
S.Indirect Bilirubin: 0.9
Serum Gamma GT: 27
SGPT (ALT): 66
Serum Alk phosphatase: 124
SGOT (AST): 35
Please advise, thank you!
Dr. Riaz Reply

 October 12, 2022
Thanks for the remarks. Your SGPT is slightly raised, which indicates liver cell injury. If you are taking pain killer, that may also raise SGPT. Repeat
SGPT/SGOT after one month. As regards being overweight, keep yourself active. You can try intermittent fasting. Control sugary things and carbohydrates.
Dr. Riaz Reply

 October 12, 2022
Please see the link:
https://labpedia.net/how-to-control-weight/ (https://labpedia.net/how-to-control-weight/)
Debarati biswas Reply

 October 26, 2022
I am 30 week pregnant..I am suffering extreme itching all over the body..My sgot level 218 and my sgpt level 416..Sir Please advice me..I am suffering a
lot..
Dr. Riaz Reply

 October 26, 2022
Sometimes the itching is part of pregnancy.
Please check your bilirubin and alkaline phosphatase levels.
Please read this link, this may help you.
https://www.healthline.com/health/pregnancy/itching-during-pregnancy (https://www.healthline.com/health/pregnancy/itching-during-pregnancy)
Katherine Reply
 October 31, 2022
Hi Doctor
I am 26 yrs old female
My SGOT 20 U/L
SGPT 45 U/L
GGT 50 U/L
For medications record, I was taking Mefenamic acid to treat my sore throat for one week.
may I have your advice on my liver profile?
may i know how to lower the liver enzymes?
Saranraj Reply
Hi Doctor
I’m 34 Years Male Affected with Jaundice and Taken the below test report on 23rd October and met a General Doctor . He advised to take Liv 52 Tablet
for 15 days(3 times in a day) . I am not facing any Pain apart from lighter body tired. Kindly suggest me what to do next sir?
My Report taken on 23.10.22 :
LIVER FUNCTION TEST with GGT
SERUM G G T 210.5 U/L
SERUM SGOT 900 U/L
SERUM SGPT 1549 U/L
SERUM BILIRUBIN TOTAL :6.71 mg/dl
SERUM BILIRUBIN DIRECT: 5.23 mg/dl SERUM BILIRUBIN INDIRECT : 1.48 mg/dl
SERUM ( Hepatitis B ) Non reactive 0.36
SERUM ANTI HCV (C VIRUS) Nonreactive (0.09)
Pls suggest Doctor ,Can I continue the Liv 52 tablet another one week?
Saranraj Reply
Hi Doctor
I’m 34 Years Male Affected with Jaundice and Taken the below test report on 23rd October and met a General Doctor . He advised to take Liv 52 Tablet
for 15 days(3 times in a day) . I am not facing any Pain apart from lighter body tired. Kindly suggest me what to do next sir?
My Report taken on 23.10.22 :
LIVER FUNCTION TEST with GGT
SERUM G G T 210.5 U/L
SERUM SGOT 900 U/L
SERUM SGPT 1549 U/L
SERUM BILIRUBIN TOTAL :6.71 mg/dl
SERUM BILIRUBIN DIRECT: 5.23 mg/dl SERUM BILIRUBIN INDIRECT : 1.48 mg/dl
SERUM ( Hepatitis B ) Non reactive 0.36
SERUM ANTI HCV (C VIRUS) Nonreactive (0.09)
Pls suggest Doctor ,Can I continue the Liv 52 tablet another one week? Nothing to worry right?
Abhinav Reply
SGOT – 39 U/l
SGPT-50 U/l
ALKALINE PHOSPHATASE -80U/L
ALBUMIN – SERUM -4.4 g/dl
SERUM GLOBULIN -3.00 g/dL
and Lipid profile is –
Total cholesterol-183 mg/dl
Triglyceride- 198 mg/dl
HDL- 58 mg/dl
VLDL- 39.6 mg/dl
LDL- 85.4
Non-Hdl-125
LDL/HDL RATIO- 1.47 %
TOTAL/HDL RATIO – 3.16
please advice is there any thing to worry?
Dr. Riaz Reply

SGPT is raised, which indicates liver cell injury. This may be due to medications like a pain killers. Triglycerides are also raised. She needs to take a low-fat
diet. Please repeat the liver function test after one month.
Kumar Reply
Good Eve Sir ,
My Name is Kumar ,age is 34 and my LFT Results is below
SERUM GGT – 50.4 U/L , SERUM SGOT -148 U/L , SERUM SGPT -264 U/L
SERUM ALKALINE PHOSPATE -88 U/L.
SERUM BILIRUBIN TOTAL – 2.93 mg/dl (Direct -1.96 & Indirect-0.99)
SERUM PROTEIN TOTAL – 7.3 gm/dl
SERUM ALBUMIN SERUM – 4.3 g/dl
SERUM GLOBULIN – 3.0 gm/dl & SERUM A/G RATIO – 1.4
* URINE COMPLETE :
URINE Colour -Light Yellow ,URINE PH-6.5 ,
Urine Specific Gravity -1.004 .
Urine (Protein,Keton &Glucose)- Negative
Urine Urobilinogen -Normal
Urine (Bilirubin &Nitrite)-Negative
Urine (RBC,WBC,YEAST CELLS ,Bacteria,Cast)-0.0
Please advise Doctor….Thank you in advance
Dr. Riaz Reply

Your SGPT/SGOT is raised, indicating liver cell injury. I hope you are not taking alcohol. Please provide me with more history.
umar Reply
December 1, 2022
ear Sir ,
hank you for your reply ! Regarding My alcohol usage – I am a social drinker & I used to have alcohol once in a month only , but in last 6 months I used to
ave thrice a week due to work pressure . Now for past 1 month I am not using alcohol. Will it be a reason??
In between of this last 6 months I used to follow my own diet plan ( I Was skipped daily breakfast 4 times in a week , used to have cooked vegtable and liite
urd rice at noon on every day and in Night I used to have rasam rice and curd rice on daily basis ). Will it be a reason ?
y USG Report – ABDOMEN & PELVIS

VER – Liver is normal in size (measures-14cm) & shows normal echotexture , No focal liver lesion .No Intra hepatic biliary radical dilatation seen.
ALL BLADDER – Is adequately distended.No calculus or cholecystitis seen
ANCREAS – Appears normal in size and shows uniform echo texture.The pancreatic duct is normal .No calcifications are seen
PLEEN – Appears normal in size and it shows echo texture. It mesures 11.9 cm in long axis.
GHT KIDNEY – Right Kidney measures – 10.4 * 3.9cm
he shape ,size and contour of right kidney appears normal.
ortico medullary differentiation is within normal. No evidence of pelvicalyceal dilatation.No calculi seen.
EFT KIDNEY – Left Kidney measures -10.4 * 4.8cm
he shape ,size and contour of left kidney appears normal.
ortico medullary differentiation is within normal. No evidence of pelvicalyceal dilatation.No calculi seen.
RINAY BLADDER – Is Normal Contour .No Intra Luminal echoes are seen
ROSTATE – Prostate appears normal ,Measures -2.3*2.5*3cms (Vol-9cc)
GHT ILIAC FOSSA – No Focal fuid collections seen
o Evidence of herina seen in anterior abdominal wall.
LS ADVICE DOCTOR . I AM WAITING FOR YOUR REPLY
Riaz Reply
cember 1, 2022
nk you are doing good. Once a month social drink will not damage your system, particularly the liver. This is not advisable to skip breakfast. The best would
ake 2 to 4 glasses of water on an empty stomach, then after 30 minutes to take breakfast.
Mahabaleshappa Reply
Good noon sir
My self mahabaleshappa .k
My sgot 200
Sgpt 500
Billirubin total 6.03
Billirubin direct 5.02
Bilirubin indirect 1.01
Day by day increasing nd decreasing both are happing sir
Dr. Riaz Reply

Your liver functions are disturbed. Please check your viral hepatitis profile (HBV, HCV, and HAV).
Nishad Reply
Sir i am 44 yrs MaleHeight = 5.10 ft:inches 88 kg weight & Regular use of Alcohol intake ..since last 12yrs | Take healthy diet + regular execerise (225
heart points/week) as per Google Fit app
Recently done Annual Health Check, and as per ultrasound Liver measures = 12.90cm & both lobes show Grade 2 fatty changes (Grade 2 fatty liver)
however liver parameters show in report as normal :
Total Bilirubin = 0.306 mg/dl
Direct Bilirubin = 0.12
Indirect Bilirubin = 0.19
SGPT/ALT = 20.30
Creatinine = 0.80
All other parameters including cholestrol are Normal. Kidneys Normal, Echo Cardio Normal
Sonography Test Impressions :
Grade 2 fatty liver
Mild Splenomegaly
Sir, Is Grade 2 fatty liver re-versible ?? If yes then, how much time it will take to reverse liver health to normal ?
Is there any indication of liver damage as per above parameters ?
Kindly provide your valuable feed back . Thanks much.
Dr. Riaz Reply

No doubt that liver functions are normal, but due to alcohol use, fatty changes in the liver have started. That will leads to cirrhosis of the liver, which is not
a reversible change. If you stop taking alcohol now, there will definitely be an improvement in liver changes.
Nishad Reply
Thank you Riaz sir for your guidance..
Till how much time i need to cease/stop alcohol intake in order to completely reverse grade 2 fatty changes ? 4 weeks / 3months / 9 months ? Will not
have alcohol at all during this time.
Can in-take of extract of Moringa Oleifera (Drumstick) + Acacia Arabica (Babool) cause fatty liver / heptacellular changes in Liver ? I take this
combination of extract in warm water daily once for knee joints .
Will go for US (UltraSound) post confirmed period but may not be able to completely avoid alcohol in the future !
Thanks in advance.
Dr. Riaz Reply

I think stopping alcohol is the only answer. If you start again, then again liver will be damaged. If you want alcohol, try having a social drink once a week
or a month.
haslian Reply
Hello Dr. Riaz,
I have had hepatitis A for 3 months, my bilirubin has went down to 8.4 mg/dL from its peak at 15.5 mg/dL. However my SGOT went back up from 44 to
59 U/L (previously peaked at 192 U/L), and the same with my SGPT, it went back up from 39 to 83 U/L (previously peaked at 755 U/L). Is it normal to
have fluctuation during the recovery phase?
Dr. Riaz Reply

Hepatitis A is a self-limiting disease. SGOT/SGPT level may fluctuate, and it should become normal when the bilirubin level is normal.
Tasbihullah Reply
Sir my 2 years daughter ALT is 691 microliter with orange red Urine what I should do further
Dr. Riaz Reply

You need to do a complete liver function test with a viral hepatitis profile (HBV, HCV, HAV).
Dr. Riaz Reply

Please send me complete liver function tests and viral hepatitis (HBV, HCV, HAV) profiles.
Manu Reply
I am having sgpt 73 and sgot 42 all other liver functions are normal.Please advice some remedy
Dr. Riaz Reply

Please check your viral hepatitis profile (HBV, HCV). Please let me know the GGT (gamma GT) level. I hope you are not taking pain killer medication.
Oliver Reply
 January 2, 2023
I have SGPT/ALT 10.6 mmo/L, please advice
Dr. Riaz Reply

 January 3, 2023
This is in the normal range. No need to worry.
Joyvic Reply
 January 8, 2023
Hi
My sgpt is 68
Sgot 37
Is it dangerous?
What should I prevent?
Dr. Riaz Reply

 January 9, 2023
SGPT is raised, and it indicates liver cell injury. Please check your viral hepatitis profile (HBV, HCV). I hope you are not taking painkillers or any other
drinks.
Nishad Reply
 January 10, 2023
Riaz sir,
I had posted on this forum as on 22nd Nov 2022 – Alcoholic Fatty Liver (Grade 2) .
As per that report of NOV 2022 :
Total Bilirubin = 0.306 mg/dl
Direct Bilirubin = 0.12
Indirect Bilirubin = 0.19
SGPT/ALT = 20.30
Creatinine = 0.80
All other parameters including cholestrol are Normal. Kidneys Normal, Echo Cardio Normal
Sonography Test Impressions :
Grade 2 fatty liver
Mild Splenomegaly
—————-
Yesterday got my LFT + USG Abdomen done : (No change in diet intake + 1 hr daily excercise)
> Completely abstained from any form of alcohol
As per recent report ie 10th Jan 2023 , Grade 2 has changed to Grade 1 now :
Total Protein = 6.77 gm/dl
Albumin,Serum = 4.62 gm/dl
Globulin = 2.15 (bold in report)
A/G Ratio = 2.15
SGOT (AST) = 16.98
SGPT (ALT) = 13.20
Alkaline Phosphatase = 61.27
Total Bilirubin = 0.47
Conjugated Bilirubin(Direct) = 0.23
Un-Conjugated Bilirubin(Indirect) = 0.24
Gamma GT = 24.15 IU/L
In USG report : “Liver is normal in size,outline and shows mild diffuse increased parenchymal echogenicity, suggestive of Grade 1 Fatty Changes. No
focal lesson is seen. IHBRs are not dilated.
Spleen size is normal & outline . (In Nov2022 : Mild Slenogemaly
Recent report Impression feedback:
> Grade 1 Hepatic Steatosis
> Splenic Cyst
Dr. Riaz Reply

 January 11, 2023
Your liver functions are normal. The liver fatty change will improve with time. The splenic cyst needs to be further work-up. Please take more fruits which
will help liver to become normal.
Take plenty of water and liquids.
Nishad Reply
 January 11, 2023
Thanks much Riaz sir.
Kindly suggest importance of Globulin = 2.15 (bold in report) value when Liver function is normal ?
Dr. Riaz Reply

 January 11, 2023
Globulin level is normal. No need to worry.
Abhinav Reply
 January 13, 2023
Hello Dr. Riaz,
My mom’s angiography report shows Insignificant CAD. Do i need to worry?
Abhinav Reply
 January 15, 2023
SGOT – 65.2 U/l
SGPT-95.1 U/l
ALKALINE PHOSPHATASE -129.3 U/L
ALBUMIN – 4.3 g/dl
GLOBULIN -2.90 g/dL
GGT -241.1 U/L
HBsAg – Non reactive
HCV – Non-reactive
Do i need to worry?
Abhinav Reply
 January 15, 2023
SGOT – 65.2 U/l
SGPT-95.1 U/l
ALKALINE PHOSPHATASE -129.3 U/L
ALBUMIN – 4.3 g/dl
GLOBULIN -2.90 g/dL
GGT -241.1 U/L
HBsAg – Non reactive
HCV – Non-reactive
Do i need to worry?
Dr. Riaz Reply

 January 16, 2023
SGOT/SGPT is raised, indicating liver cell injury. I hope she is not taking pain killer. She needs consultation with a gastroenterologist. I will recommend
doing an ultrasound abdomen.
Abhinav Reply
 January 16, 2023
Ultrasound abdomen shows grade 1 fatty liver changes everything else is normal. She got discharged last sunday and on medication like dollo 650 for
3-4 days after discharge.
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SGPT (Serum Glutamic-Pyruvic Transaminase), ALT (Alanine

SGPT (Serum Glutamic-Pyruvic Transaminase)

Precautions For SGPT (ALT)

Indications for SGPT

Definition of ALT (SGPT):

Distribution of SGPT (ALT):

Variation of the ALT:

Distribution of SGPT (ALT) in the liver:

Liver cell injury:

3. SGPT activity persists longer than the SGOT.

SGPT (ALT) biochemical reaction and variations in different conditions:

SGPT level in various tissue as compared to serum:

Organs Times more as compared to the normal serum level

Skeletal muscle 300

Ratio of enzymes AST/ALT = <1 AST/ALT = >1

AST/ALT 1. Acute hepatitis 1. Alcoholic liver diseases (Cirrhosis)

Diagnostic application of the SGPT (ALT):

NORMAL SGPT (ALT) level

Age Male U/L Female U/L

Adult / child = 4 to 36 unit/L at 37 °C

Men = 10 to 30 units /L (some labs normal is 10 to 40 U/L).

The increased SGPT (ALT) level is seen in:

Acute Viral hepatitis SGPT (ALT) Pattern:

Table showing the increase of SGPT in various conditions:

Viral hepatitis and liver diseases may reach 100 times

Infectious hepatitis ALT > AST

Toxic hepatitis Extremely high level

Infectious mononucleosis 20 times

Intrahepatic cholestasis maybe raised

Extrahepatic cholestasis Very high level

Cirrhosis 4 to 5 times or higher

Metastatic carcinoma 5 to 10 times

Acute myocardial infarction within normal limits or a very mild increase

Progressive muscular dystrophy May reach 8 times

Dermatomyositis May reach 8 times

>9000 U/L seen in Alcohol-acetaminophen syndrome.

The main feature of SGPT (ALT) and SGOT (AST):

Normal range 5 to 35 IU/L 10 to 40 IU/L

Half-life in blood 35 to 57 hours (3 to 5 days) 12 to 22 hours

Change with acute inflammatory conditions It is extremely sensitive It is moderately sensitive

The rise in metastatic or primary neoplasm It is moderate or no change It is markedly increased

In cirrhosis It is a mild to moderate increase It is moderately increase

In acute myocardial infarction It is a mild to moderate increase It is markedly increase

Question 1: What is the half-life of SGPT?

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