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LAMPIRAN

Lampiran 1 Daftar Riwayat Hidup

Nama Lengkap : Padmi Yulianti

Nim : 201810410311175
Tempat, Tanggal Lahir : Dayu, 1 Maret 2000
Jenis Kelamin : Perempuan
Alamat Asal : Desa Lagan, Kecamatan Karusen Janang, Kab.
Barito Timur, Prov. Kalimantan Tengah.
No. Handphone (WA) : 081520210203
Email : fatmi012000@gmail.com
Riwayat Pendidikan :
No. Jenis Pendidikan Tahun
1. SD Negeri 3 Dayu 2006 - 2012
2. MTs Normal Islam Puteri RAKHA 2012 – 2015
3. MA Normal Islam Puteri RAKHA 2015 – 2018
4. Farmasi Universitas Muhammadiyah 2018 - sekarang
Malang

Malang, 23 Oktober 2021

Yang Menyatakan,

Padmi Yulianti
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Lampiran 2 Senyawa metabolit sekunder curcuma longa Dr.Duke

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Lampiran 3 Canonical Smiles Senyawa metabolit sekunder curcuma longa

NO NAMA SENYAWA CANONICAL SMILES
(+)-(S)-AR-
1 TURMERONE CC1=CC=C(C=C1)C(C)CC(=O)C=C(C)C
2 (+)-AR-TURMERONE CC1=CC=C(C=C1)C(C)CC(=O)C=C(C)C
(+)-
ALPHAPHELLANDREN
3 E CC1=CCC(C=C1)C(C)C
4 (+)-SABINENE CC(C)C12CCC(=C)C1C2
1,5-BIS-(4-HYDROXY-
3- METHOXYPHENYL)- COC1=C(C=CC(=C1)C=CC(=O)C=CC2=
5 1,4- PENTADIEN-3-ONE CC(=C(C=C2)O)OC)O
1,7-BIS-(4-HYDROXY-
3- METHOXYPHENYL)-
1,4,6- HEPTATRIEN-3- COC1=C(C=CC(=C1)C=CC=CC(=O)C=C
6 ONE C2=CC(=C(C=C2)O)OC)O
1,7-BIS-(4-
HYDROXYPHENYL)-1- C1=CC(=CC=C1CCC(=O)CC(=O)C=CC2
7 HEPTENE-3,5-DIONE =CC=C(C=C2)O)O
8 1,8-CINEOLE CC1(C2CCC(O1)(CC2)C)C
4''-(3''-METHOXY-4''-
HYDROXYPHENYL)-
2''- OXO-3''-
ENEBUTANYL-3-(3'-
METHOXY-4'-
HYDROXYPHENYL)- COC1=C(C=CC(=C1)C=CC(=O)COC(=O)
9 PROPENOATE C=CC2=CC(=C(C=C2)O)OC)O
10 ALPHA-ATLANTONE CC1=CCC(CC1)C(=CC(=O)C=C(C)C)C
ALPHA-
11 PHELLANDRENE CC1=CCC(C=C1)C(C)C
12 ALPHA-PINENE CC1=CCC2CC1C2(C)C
13 ALPHA-TERPINENE CC1=CC=C(CC1)C(C)C
14 ALPHA-TERPINEOL CC1=CCC(CC1)C(C)(C)O
15 ALPHA-TURMERONE CC1=CCC(C=C1)C(C)CC(=O)C=C(C)C
16 ASCORBIC-ACID C(C(C1C(=C(C(=O)O1)O)O)O)O
17 AZULENE C1=CC=C2C=CC=C2C=C1
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=C
C=CC=C(C)C=CC=C(C)C=CC2=C(CCCC
18 BETA-CAROTENE 2(C)C)C)C)C
19 BETA-PINENE CC1(C2CCC(=C)C1C2)C
CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4
20 BETA-SITOSTEROL C3(CCC(C4)O)C)C)C(C)C
21 BETA-TURMERONE CC(CC(=O)C=C(C)C)C1CCC(=C)C=C1
BISDEMETHOXYCURC C1=CC(=CC=C1C=CC(=O)CC(=O)C=CC
22 UMIN 2=CC=C(C=C2)O)O
BISABOLA-3,10-DIEN-
23 2-ONE CC1=CC(=O)C(CC1)C(C)CCC=C(C)C
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24 BISACUMOL CC1=CC=C(C=C1)C(C)CC(C=C(C)C)O
CC(CC(=O)C=C(C)C)C1CC(C(C=C1)(C)O
25 BISACURONE )O
26 BORNEOL CC1(C2CCC1(C(C2)O)C)C
27 CAFFEIC-ACID C1=CC(=C(C=C1C=CC(=O)O)O)O
28 PROCURCUMENOL CC1=CC(=O)C(=C(C)C)CC2C1CCC2(C)O
COC1=C(C=CC(=C1)C=CC(=O)COC(=O)
29 CALEBIN A C=CC2=CC(=C(C=C2)O)OC)O
30 CAMPHENE CC1(C2CCC(C2)C1=C)C
31 CAMPHOR CC1(C2CCC1(C(=O)C2)C)C
32 CAPRYLIC-ACID CCCCCCCC(=O)O
P-
TOLYMETHYLCARBIN
33 OL CC1=CC=C(C=C1)C(C)O
34 CINEOL CC1(C2CCC(O1)(CC2)C)C
35 CINNAMIC-ACID C1=CC=C(C=C1)C=CC(=O)O
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(
36 QUERCETIN C=C3O2)O)O)O)O)O
CCC(C)C.CCC(CC(C)C1=CC=CC=C1)C2
37 RESIN =CC=C(C=C2)C[N+](C)(C)C.N.[Cl-]
38 CUMINYL-ALCOHOL CC(C)C1=CCC(C=C1)CO
39 CURCUMENE CC1=CC=C(C=C1)C(C)CCC=C(C)C
COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C
40 CURCUMIN =CC2=CC(=C(C=C2)O)OC)O
41 CURCUMOL CC1CCC2C13CC(C(O3)(CC2=C)O)C(C)C
42 CURDIONE CC1CCC=C(CC(=O)C(CC1=O)C(C)C)C
CURLONE (BETA
43 TURMERONE) CC(CC(=O)C=C(C)C)C1CCC(=C)C=C1
CC1=COC2=C1C(=O)C(C(C2)(C)C=C)C(
44 CURZERENONE =C)C
COC1=C(C=CC(=C1)C=CC2=CC(=O)CC(
45 CYCLOCURCUMIN O2)C3=CC(=C(C=C3)O)OC)O
D-ALPHA-
PHELLANDRENE
(ALPHA
46 PHELENDRENE) CC1=CCC(C=C1)C(C)C
47 D-CAMPHENE CC1(C2CCC(C2)C1=C)C
48 D-CAMPHOR CC1(C2CCC1(C(=O)C2)C)C
49 D-SABINENE CC(C)C12CCC(=C)C1C2
50 DEHYDROCURDIONE CC1CCC=C(CC(=O)C(=C(C)C)CC1=O)C
DEMETHOXYCURCUM COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C
51 IN =CC2=CC=C(C=C2)O)O
DESMETHOXYCURCU COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C
52 MIN (DEMET) =CC2=CC=C(C=C2)O)O
DICINNAMOYLMETHA C1=CC=C(C=C1)C=CC(=O)CC(=O)C=CC
53 NE 2=CC=CC=C2
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COC1=C(C=CC(=C1)CCC(=O)CC(=O)C=
54 DIHYDROCURCUMIN CC2=CC(=C(C=C2)O)OC)O
CC12CCC3C(C1CCC2(C#C)O)CCC4=C3
55 EO (ETINIL ESTRdiol C=CC(=C4)O
EPI-
56 PROCURCUMENOL CC1=CC(=O)C(=C(C)C)CC2C1CCC2(C)O
57 EUGENOL COC1=C(C=CC(=C1)CC=C)O
58 GAMMA_ATLANTONE CC1=CCC(=C(C)CC(=O)C=C(C)C)CC1
59 GAMMA-TERPINENE CC1=CCC(=CC1)C(C)C
60 GERMACRENE CC1=CCCC(=CCC(CC1)C(=C)C)C
GERMACRON-(4S',5S)- CC1=CCCC2(C(O2)CC(=C(C)C)C(=O)C1)
61 EPOXIDE C
62 GERMACRONE CC1=CCC(=C(C)C)C(=O)CC(=CCC1)C
63 GLUCOSE C(C1C(C(C(C(O1)O)O)O)O)O
64 GUAIACOL COC1=CC=CC=C1O
65 ISOBORNEOL CC1(C2CCC1(C(C2)O)C)C
66 ISOPROCURCUMENOL CC(=C1CC2C(CCC2(C)O)C(=C)CC1=O)C
L-ALPHA-
67 CURCUMENE CC1=CC=C(C=C1)C(C)CCC=C(C)C
68 L-BETA-CURCUMENE CC1=CCC(=CC1)C(C)CCC=C(C)C
69 LIMONONE CC1=CCC(CC1)C(=C)C
70 LINALOOL CC(=CCCC(C)(C=C)O)C
P-METHOXY-
71 CINNAMICACID COC1=CCC(C=C1)C=CC(=O)O
MONODEMETHOXYC
URCUMIN COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C
72 (DEMETOXY) =CC2=CC=C(C=C2)O)O
73 NIACIN C1=CC(=CN=C1)C(=O)O
74 P-CYMENE CC1=CC=C(C=C1)C(C)C
75 P-COUMARIC-ACID C1=CC(=CC=C1C=CC(=O)O)O
CCCCCCCCCC(=O)O.CCCCCCCC(=O)O
SATURATED-FATTY- .CCCCC(=O)O.C(C(CO)(CO)COCC(CO)(
76 ACIDS CO)CO)O
77 TURMERONE CC1=CCC(=CC1)C(C)CC(=O)C=C(C)C
C(COCC1C(C(C(C(O1)OCCO)OCCO)OC
CO)OCCO)O.C(C1C(C(C(C(O1)O)O)O)O)
78 STARCH O
79 TERPINENE CC1=CCC(=CC1)C(C)C
CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)
80 THIAMIN CCO
TOLYL-
81 METHYLCARBINOL CC1=CC=CC=C1C(C)O
CC1=C(C=C(C=C1)C(C)CC(=O)C=C(C)C
82 TURMERONOL-A )O
CC1=CC(=C(C=C1)C(C)CC(=O)C=C(C)C
83 TURMERONOL-B )O
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CC(=C1CC2C(CCC2(C)O)C(CC1=O)(C)O
84 ZEDOARONDIOL )C
85 ZINGIBERENE CC1=CCC(C=C1)C(C)CCC=C(C)C
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Lampiran 4 Struktur 2 dimensi Senyawa Metabolit Sekunder Curcuma longa

No Kode Struktur
Senyawa
1 Mol 1

2 Mol 2

3 Mol 3

4 Mol 4

5 Mol 5
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6 Mol 7

7 Mol 8

8 Mol 24

9 Mol 26

10 Mol 27
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11 Mol 28

12 Mol 30

13 Mol 34

14 Mol 36

15 Mol 37

16 Mol 39

17 Mol 54
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18 Mol 61

19 Mol 69

20 Mol 76

21 Mol 78

22 Mol 96

23 Mol 97
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24 Mol 98

25 Mol 99

26 Mol 101

27 Mol 108

28 Mol 109

29 Mol 110

30 Mol 118
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31 Mol 116

32 Mol 137

33 Mol 133

34 Mol 139

35 Mol 148
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Lampiran 5 Form Plagiasi ( P2 )

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