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  • Compact Bone

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    dhirazhr
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    There are three main types of cells in compact bone - osteoblasts which secrete bone matrix, osteocytes which maintain bone structure and trigger bone formation in response to strain or calcium levels, and osteoclasts which resorb bone. Bone forms through two types of ossification, endochondral where hyaline cartilage acts as a blueprint, or intramembranous. Bone repair involves interactions between inhibitors like sclerostin and factors like RANK and RANKL, while cartilage contains chondroblasts and chondrocytes and comes in hyaline, elastic, and fibrocartilage forms.

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    There are three main types of cells in compact bone - osteoblasts which secrete bone matrix, osteocytes which maintain bone structure and trigger bone formation in response to strain or calcium levels, and osteoclasts which resorb bone. Bone forms through two types of ossification, endochondral where hyaline cartilage acts as a blueprint, or intramembranous. Bone repair involves interactions between inhibitors like sclerostin and factors like RANK and RANKL, while cartilage contains chondroblasts and chondrocytes and comes in hyaline, elastic, and fibrocartilage forms.

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    17 views1 page

    Compact Bone

    Uploaded by

    dhirazhr
    There are three main types of cells in compact bone - osteoblasts which secrete bone matrix, osteocytes which maintain bone structure and trigger bone formation in response to strain or calcium levels, and osteoclasts which resorb bone. Bone forms through two types of ossification, endochondral where hyaline cartilage acts as a blueprint, or intramembranous. Bone repair involves interactions between inhibitors like sclerostin and factors like RANK and RANKL, while cartilage contains chondroblasts and chondrocytes and comes in hyaline, elastic, and fibrocartilage forms.

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    © All Rights Reserved
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    of 1

    Compact bone

    Types of cell

    a. Osteoblast
    Function: secrete bone matrix
    b. Osteocyte (the regulator)
    Function: maintain bone structure. E.g. when mechanical strain happened  trigger bone
    formation, when low level of ca2+ in blood  bone breakdown
    c. Osteoclast
    Function: bone resorption

    Ossification

    a. Endochondral
    In utero, starts with hyaline as a blueprint
    b. Intramembranosa

    Bone repair

    Interaction

    A. Sclerostin (bone formation inhibitor)


    B. RANK and RANKL

    Cartilage

    Types of cartilage

    a. Hyaline
    b. Elastic
    c. Fibrocartilage

    Types of cell

    a. Chondroblast
    b. Chondrocyte

    Ossification process

    Hormones that play a role in cartilage formation

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