The document asks if cleaning glass slides helps with better bonding of PDMS to glass for microfluidics devices, as the author was experiencing bonding and leakage issues when using hand pressure. The author describes their glass cleaning process as soaking in sulfuric acid overnight, then rinsing with water and soaking in methanol, isopropyl alcohol and sometimes acetone before UV-ozone treatment, and provides additional details about their microfluidics channel dimensions, PDMS ratio used, and glass slide type.
The document asks if cleaning glass slides helps with better bonding of PDMS to glass for microfluidics devices, as the author was experiencing bonding and leakage issues when using hand pressure. The author describes their glass cleaning process as soaking in sulfuric acid overnight, then rinsing with water and soaking in methanol, isopropyl alcohol and sometimes acetone before UV-ozone treatment, and provides additional details about their microfluidics channel dimensions, PDMS ratio used, and glass slide type.
The document asks if cleaning glass slides helps with better bonding of PDMS to glass for microfluidics devices, as the author was experiencing bonding and leakage issues when using hand pressure. The author describes their glass cleaning process as soaking in sulfuric acid overnight, then rinsing with water and soaking in methanol, isopropyl alcohol and sometimes acetone before UV-ozone treatment, and provides additional details about their microfluidics channel dimensions, PDMS ratio used, and glass slide type.
Does cleaning glass-slide help for better PDMS-glass bonding?
Facing trouble (bonding-leakage) while using hand-pressure to pass liquid through my
microfluidics device. I used UVO-cleaning instead of plasma-bonding (PB not available). The way I cleaned the glass slide before UVO step: H2SO4 (70%) Overnight> dH2O > Soak with Methanol (~100%) > IPA (~100) > also add Acetone (~100) sometimes > UVO- treatment. Microfluidics Channel precision = 20 um PDMS (10:1) Glass slide = Microscope cover slip 25*45mm Please let me know if you need more clarification. Thank you for your suggestion. Cleaning Glass Lab-On-A-Chip Devices Microfluidic Chip Development and Manufacturing