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Abstract: Tibiotalocalcaneal arthrodesis is a salvage procedure. We Tibiotalocalcaneal arthrodesis (TTCA) is a salvage procedure.
report on the operative technique, the importance of addressing con-
It is an alternative to amputation in nonbraceable hindfoot
comitant ankle and foot deformities when present and the outcomes
deformities, disabling fixed deformities, failed ankle arthrod-
(radiologic fusion rate, limb salvage rate, and global patient
esis, failed total ankle arthroplasty, talar osteonecrosis and
satisfaction) with a hindfoot arthrodesis nail. It was used for tibiota-
avascular necrosis, severe combined ankle and subtalar
localcaneal arthrodesis on 63 consecutive patients (6 bilateral proce-
arthritis, neurological deficit, and tumor.1–4
dures). The minimum follow-up was 12 months; the mean age was 59
Historically, a solid, functional, pain-free arthrodesis is
(range, 24 to 87) years, with 69% male. At 3 months, the fusion rate
difficult to achieve. Previous studies have demonstrated non-
was 77.7% (49/63); 6-month fusion rate was 95% (60/63). The overall
union rates as high as 10% to 25%.5–9 Screws, plates, external
complication rate was 12.6% (8/63). There was a 100% limb salvage
fixators, and intramedullary nails (IMN) (both hindfoot fusion
rate. Fifty-seven concomitant procedures were performed on 38
specific and otherwise) have been used, with the aim of surgery
patients at time of nail insertion.
being the provision of a stable, well aligned, pain-free, shoe-
able, and ambulatory foot.
Level of Evidence: Diagnostic Level 4. See Instructions for Authors
More recently use of IMN designed for TTCA have
for a complete description of levels of evidence.
shown very high fusion rates.10,11 Intramedullary fusion tech-
Key Words: tibiotalocalcaneal arthrodesis, hindfoot arthrodesis, niques in comparison with other constructs have the advan-
intramedullary nail, ankle and subtalar arthritis, hindfoot deformity tages of being load-sharing, have greater rotational stability
(Tech Foot & Ankle 2015;14: 146–155)
and bending stiffness, have rigid and stable fixation, allow for
sequential compression, have an anatomic design with valgus
curve, and can be percutaneously inserted.4,10–13
LEARNING OBJECTIVES Multiple biomechanical studies have compared intra-
After completing this activity, the learner should be better medullary nailing to other fusion devices in TTCA. Screw
able to: configurations, blade and locked plates, and external fixators
Select and recognize patient-specific treatment approaches have been used. Intramedullary nailing has demonstrated
for concomitant foot and ankle procedures. greater rigidity, final stiffness, less deformity with com-
Identify patients at risk of complications from Tibiotalo- pression, and higher load-to-failure stressors in biomechanical
calcaneal Arthrodesis (TTCA). and cadaveric models.3,12,14–16 Progress of IMN design to
Understand the aims of Tibiotalocalcaneal Arthrodesis incorporate angle-stable locking screws has also increased
(TTCA). biomechanical advantages to earlier nail designs with only
From the *Orthopaedic Registrar, Department of Orthopaedics, Mackay Base Hospital, West Mackay; wOrthopaedic Surgeon, Visiting Medical Officer,
Department of Orthopaedics, Princess Alexandra Hospital, Woolloongabba; zUniversity of Queensland, St Lucia; yOrthopaedic Principal House Officer,
Department of Orthopaedics, Ipswich General Hospital, Ipswich; and 8Visiting Medical Officer, St Andrews War Memorial Hospital, Brisbane, Qld,
Australia.
Dr. Lutz has disclosed that he is a member of the speaker’s bureau for Stryker and his spouse/life partner (if any) has no financial relationships with or
financial interests in, any commercial companies pertaining to this educational activity. Dr. Jorgensen and LCMEI staff are in a position to control the
content of this CME activity and their spouses/life partners (if any) have disclosed that they have no financial relationships with, or financial interests in,
any commercial organizations pertaining to this educational activity.
Lippincott CME Institute has identified and resolved all conflicts of interest concerning this educational activity.
INSTRUCTIONS FOR OBTAINING AMA PRA CATEGORY 1 CREDITt
Techniques in Foot & Ankle Surgery includes CME-certified content that is designed to meet the educational needs of its readers. This activity is available for
credit through December 31, 2015.
Earn CME credit by completing a quiz about this article. You may read the article here, on the TFAS website, or in the TFAS iPad app, and then complete the
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medical education for physicians.
Credit Designation Statement
Lippincott Continuing Medical Education Institute, Inc., designates this journal-based CME activity for a maximum of 1 (one) AMA PRA Category 1
Creditt. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Address correspondence and reprint requests to Nicholas B. Jorgensen, MBBS, BSc, Department of Orthopaedics, Ipswich General Hospital, Chelmsford
Avenue, Ipswich, 4305, Qld, Australia. E-mail: jorgensen.nicholas@gmail.com.
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146 | www.techfootankle.com Techniques in Foot & Ankle Surgery Volume 14, Number 3, September 2015
static screw design.15,17 Our study suggests that the bio- achieving 89% fusion rate, improvement in clinical situation
mechanical laboratory results are translated in the clinical (82%), increase in American Orthopaedic Foot and Ankle
setting. Score of 37, and 45% complication rate (1 below knee
Clinical outcomes for intramedullary nailing for TTCA amputation, 1 nonunion, 3 delayed union, removal of metal
have been previously investigated and provide a guide to ware: 4 nails, 12 screws).
fusion rates and patient satisfaction. Shah et al’s 201112 review
of clinical trials suggested superior results in conditions with
impaired bone quality including rhuematoid arthritis, diabetes,
and neuroarthropathy. The ability to deliver compression and INDICATIONS/CONTRAINDICATIONS
rigid and stable fixation has allowed for more reliable fusion Retrograde intramedullary TTCA is an alternative to amputation
rates and a higher limb salvage rate in late stage ankle insta- in nonbraceable hindfoot deformities, disabling fixed deform-
bility hindfoot deformities.12,13,18 Other retrospective studies ities, failed ankle arthrodesis, failed total ankle arthroplasty, talar
using intramedullary nailing for TTCA have shown improved osteonecrosis and avascular necrosis, severe combined ankle and
patient outcomes (Table 1).6,10,18,19,22 subtalar arthritis, neurological deficit, and tumor.1–4 The most
Mückley et al,10 followed up 55 identical arthrodesis nails common etiology in our experience is combined ankle and
for a mean of 16 months, achieving 96% fusion rate, sat- subtalar arthritis and Charcot arthropathy (Table 2).
isfaction (91%), and 25% complication rate (shaft fracture, DeVries et al1 analyzed 179 TTCA using designs of IMN,
reoccurrence osteomyelitis, DVT, nonunion, and removal of and showed a limb salvage rate of 88.2% (21 limbs ampu-
nail). Taylor et al11 achieved an 83.6% fusion rate at 3.7 tated). From this study, DeVries et al1 developed an odds ratio
months, with 83% good/excellent patient satisfaction and a for risk of amputation, with diabetes (7.01), revision surgery
17% complication rate (2 below knee amputation, deep (6.23), preoperative ulceration (2.99), and increased age hav-
infection, and removal of metal ware). Budnar et al20 reviewed ing a correlation with amputation.
45 TTC fusion locking nails (Depuy) for a mean of 48 months,
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Jorgensen and Lutz Techniques in Foot & Ankle Surgery Volume 14, Number 3, September 2015
FIGURE 1. Lateral incision with exposure of distal third of FIGURE 2. Exposure of ankle joint (A) and talocalcaneal joint (B)
(deformed) fibular, protected with retractors (A) and with with laminar spreaders allows complete access to denude
acetabular reamer (B). articular surfaces of cartilage.
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Jorgensen and Lutz Techniques in Foot & Ankle Surgery Volume 14, Number 3, September 2015
FIGURE 5. Lateral ankle (A) and weight-bearing anteroposterior (AP) foot (B) radiographs of a 60-year-old male with severe hindfoot
and talonavicular joint arthritis. Weight-bearing lateral ankle (C) and weight-bearing AP foot (D) radiographs after hindfoot and
talonavicular joint fusions.
series of patients. Of our patients that have nonunions (3 successful limb salvage has been achieved through ongoing
patients, 5%), all are diabetic with Charcot arthropathy customized, immobilizing footwear.
affecting the hindfoot and aged 53, 63, and 73 years. The There was no correlation between nail dimensions and the
tibiotalar joint failed to fuse in all 3 instances. However, need for removal of the hindfoot arthrodesis nail for tibial
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Jorgensen and Lutz Techniques in Foot & Ankle Surgery Volume 14, Number 3, September 2015
FIGURE 6. Preoperative anteroposterior (AP) ankle (A) and lateral ankle (B) radiograph of severe hindfoot varus deformity from
neurogenic etiology (Spinal Cord Injury). Two-week postoperative AP ankle (C) and lateral ankle (D) radiograph of tibiotalocalcaneal
arthrodesis with a hindfoot arthrodesis nail in a below knee plaster of Paris back slab.
preoperative state and 93% (27/29) would repeat the surgery, information as an insight into the current functional status of
indicating a high level of satisfaction. Of the 2 patients that those patients that have had a hindfoot fusion.
would not repeat their surgery, the FFI-R scores were 95 and The success demonstrated in our study and operative
118. There is limited ability to interpret a single postoperative technique is at least equivalent and has favorable fusion rates
FFI-R in a cohort of patients, but we have provided this with comparable studies.10,11 Our systematic use of resected
152 | www.techfootankle.com Copyright r 2015 Wolters Kluwer Health, Inc. All rights reserved.
fibular for bone grafting, combined with meticulous cartilage 9. Niinimaki TT, Klemola TM, Leppilahti JI. Tibiotalocalcaneal
denudation and drilling of subchondral surfaces is thought to arthrodesis with a compressive retrograde intramedullary nail: a report
assist fusion in a patient cohort with prohibitive biological of 34 consecutive patients. Foot Ankle Int. 2007;28:431–434.
states. Mückley et al10 agreed with the importance of bone 10. Mückley T, Klos K, Drechsel T, et al. Short-term outcome of retrograde
graft. Taylor et al11 did not specify the use of intraoperative tibiotalocalcaneal arthrodesis with a curved intramedullary nail. Foot
autograft and achieved a lower fusion rate, and required 14.5% Ankle Int. 2011;32:47–56.
revision with femoral head allograft.
11. Taylor JM, Knox RE, Guyver PM, et al. Tibiotalocalcaneal arthrodesis
The complexity and heterogeneity of deformity and
with a compressive retrograde intramedullary nail: the exeter
symptoms in our patient series is wide ranging (Table 2). We
experience of 55 consecutive patients. JBJS. 2012;94-B:60.
have performed concomitant procedures on 60% of our
patients. These range from tibial, hindfoot, midfoot, and 12. Shah KS, Alastair S, Younger AS. Primary tibiotalocalcaneal
forefoot corrections, removal of metal ware and soft tissue arthrodesis. Foot Ankle Clin N Am. 2011;16:115–136.
debridement and transfer. In 15.8% of our series, talectomy 13. Panagakos P, Ullom N, Boc SF. Salvage arthrodesis for charcot
was performed to achieve satisfactory alignment (Table 3). arthropathy. Clin Podiatr Med Surg. 2012;29:115–135.
Mückley et al10 commented on the need for tenotomies, 14. Fragomen AT, Meyers KN, Davis N, et al. A biomechanical
pedicled sural flap and plating of the talonavicular joint in 2 comparison of micromotion after ankle fusion using 2 fixation
patients, although the rate of talectomy is unknown. There is techniques: intramedullary arthrodesis nail or Ilizarov external fixator.
little information regarding concomitant procedures in other Foot Ankle Int. 2008;29:334–341.
TTCA case series. We propose that assessing and correcting all
deformities of the foot and ankle and respecting the soft tissue 15. Mückley T, Eichorn S, Hoffmeier K, et al. Biomechanical evaluation
envelope, has led to our 100% salvage rate (Fig. 6). Longer of primary stiffness of tibiotalocalcaneal fusion with
term complications, such as adjacent joint arthritis and tibial intramedullary nails. Foot Ankle Int. 2007;28:224–231.
diaphyseal pain, are potentially not captured. 16. O’Neill PJ, Logel KJ, Parks BG, et al. Rigidity comparison of locking
The risks of a single (slightly longer) anesthetic can be plate and intramedullary fixation for tibiotalocalcaneal arthrodesis.
viewed as having at least an equivalent if not lesser risk of Foot Ankle Int. 2008;29:581–586.
repeated anesthetics. This effect is even more clinically sig- 17. Muckley T, Hoffmeier K, Klos K, et al. Angle-stable and compressed
nificant in those patients aged above 70, a difficult intubation angle-stable locking for tibiotalocalcaneal arthrodesis with retrograde
or with cardiovascular instability.28 intramedullary nails: biomechanical evaluation. J Bone Joint Surg Am.
The use of a hindfoot arthrodesis nail is a reliable, safe, 2008;90:620–627.
and effective device and technique to achieve arthrodesis and
18. Anderson T, Linder L, Rydholm U, et al. Tibio-talocalcaneal
limb salvage in the treatment of ankle and hindfoot arthritis
arthrodesis as a primary procedure using a retrograde intramedullary
and deformity correction. We suggest that addressing con-
nail: a retrospective study of 26 patients with rheumatoid arthritis. Acta
comitant ankle and foot deformities need to be corrected when
Orthop. 2005;76:580–587.
present. We believe of focus on achieving a plantigrade foot
and ankle, even in cases of nonunion, salvage of the foot has 19. Boer R, Mader K, Pennig D, et al. Tibiotalocalcaneal arthodesis using a
been achieved. We present the largest consecutive series in the reamed retrograde locking nail. Clin Orthop. 2007;463:151–156.
use of this device and an operative technique that can be 20. Budnar VM, Hepple S, Harries WG, et al. Tibiotalocalcaneal
replicated independent of etiology and preoperative deformity. arthrodesis with a curved, interlocking, intramedullary nail. Foot Ankle
Int. 2010;31:1085–1095.
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Jorgensen and Lutz Techniques in Foot & Ankle Surgery Volume 14, Number 3, September 2015
CME QUESTIONS
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