Clopidogrel 75 mg tab OD + Omeprazole 40mg tab OD

Recommendations: Please avoid administration of Omeprazole. Respectfully suggesting to co-administer

H2-receptor antagonists or antacids with clopidogrel.

Discussion: Proton pump inhibitor like Omeprazole may reduce the cardioprotective effect of
clopidogrel. PPIs should only be considered in high-risk patients such as those receiving dual antiplatelet
therapy, with history of gastrointestinal bleeding or ulcer, or receiving concomitant anticoagulant
therapy.

Ciprofloxacin 500 mg tab BID + Ferrous sulfate 325 mg tab TID

Recommendations: Please administer Ciprofloxacin 2-4 hours before or 4 to 6 hours after taking Ferrous
Sulfate. Respectfully suggesting taking Ciprofloxacin (6 AM, 6 PM) and Ferrous sulfate (8 AM, 12 NN, 8
PM). Please also monitor all other medications including vitamins and herbs.

Discussion: Products which contain magnesium, aluminum, calcium, iron and/or other minerals may
interfere with absorption of ciprofloxacin and its effectiveness. For that reason, Ciprofloxacin and
ferrous sulfate should not be taken orally at the same time.

Furosemide + digoxin

Recommendations: Side effects of Furosemide such as hypokalemia and hypomagnesemia must be

treated appropriately.

Discussion: Furosemide-induced hypokalemia and hypomagnesemia can cause arrhythmias in patients

taking Digoxin. Digitalis dose adjustment may be also required.

Amlodipine + Calcium carbonate

Recommendations: Monitor the efficacy of Amlodipine or other CCBs during co-administration with
Calcium carbonate

Discussion: Calcium carbonate or other products containing calcium may reduce the effectiveness of
Amlodipine or other calcium-channel blockers