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Int. J. Oral Maxillofac. Surg.

2016; 45: 476–485


http://dx.doi.org/10.1016/j.ijom.2015.10.019, available online at http://www.sciencedirect.com

Clinical Paper
Orthognathic Surgery

Assessment of the changes in T. Baherimoghaddam1, R. Tabrizi2,


N. Naseri3, A. Pouzesh4, M. Oshagh5,
S. Torkan6

quality of life of patients with


1
Department of Orthodontics, School of
Dentistry, Yasuj University of Medical
Sciences, Yasuj, Iran; 2Department of
Craniomaxillofacial Surgery, Shiraz University

class II and III deformities of Medical Sciences, Shiraz, Iran;


3
Department of Orthodontics, School of
Dentistry, Azad University of Medical
Sciences, Shiraz, Iran; 4Department of
during and after orthodontic– Craniomaxillofacial Surgery, School of
Dentistry, Yasuj University of Medical
Sciences, Yasuj, Iran; 5Private Practice,

surgical treatment Tehran, Iran; 6Orthodontic Research Centre,


Shiraz University of Medical Sciences, Shiraz,
Iran

T. Baherimoghaddam, R. Tabrizi, N. Naseri, A. Pouzesh, M. Oshagh, S. Torkan:


Assessment of the changes in quality of life of patients with class II and III deformities
during and after orthodontic–surgical treatment. Int. J. Oral Maxillofac. Surg. 2016;
45: 476–485. # 2015 International Association of Oral and Maxillofacial Surgeons.
Published by Elsevier Ltd. All rights reserved.

Abstract. The aim of this longitudinal study was to assess and compare the oral
health-related quality of life (OHRQoL) of patients with class II and III deformities
during and after orthodontic–surgical treatment. Thirty class III and 28 class II
patients were evaluated at baseline (T0), just prior to surgery (T1), at 6 months after
surgery (T2), and at 12 months after debonding (T3). OHRQoL was assessed using
the Oral Health Impact Profile (OHIP-14). Friedman two-way analysis of variance
and the Wilcoxon signed-rank test were performed to compare the relative changes
in OHRQoL during treatment. Significant changes in the overall OHIP-14 scores
were observed during and after orthodontic–surgical treatment in both groups.
During the pre-surgical stage, psychological discomfort and psychological
disability decreased in class III patients, and class II patients experienced a
significant deterioration in psychological discomfort during the same period. Six
Key words: oral health-related quality of life;
months after surgery, patients in both groups showed improvements in
orthognathic surgery; OHIP index; dentofacial
psychological discomfort, social disability, and handicap. Physical disability and deformity.
functional limitation showed further improvement at 12 months after debonding in
class II patients. This study reaffirms that orthodontic–surgical treatment has a Accepted for publication 21 October 2015
significant effect on the OHRQoL of class III and class II patients. Available online 18 November 2015

Previous studies have indicated that treatment.1 The results of many studies other hand, some studies have reported
patients hope to improve their oral have shown that the primary motivation that certain patients prefer to improve bite
health-related quality of life (OHRQoL) for the correction of dentofacial deformity function rather than aesthetics.3,4 Several
by undergoing orthodontic–surgical is to improve facial aesthetics.2 On the studies have described the psychological

0901-5027/040476 + 010 # 2015 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
QoL and orthodontic–surgical treatment 477

advantages of orthodontic–surgical treat- osteotomies for the correction of skeletal and handicap. The questionnaire is
ment.5,6 These include changes in person- deformities using OHIP-14 at four time designed based on a five-point scale, as
ality, improvements in self-esteem, and points: prior to treatment, just before sur- follows: never (0), hardly ever (1), occa-
positive changes in lifestyle, such as gery, post-surgery, and after debonding. sionally (2), fairly often (3), and very often
improvements in personal relation- (4). Each domain score can range from 0
ships.7–9 to 8 and can be calculated by summating
Materials and methods
The evaluation of OHRQoL during or- the responses to the items within a domain.
thodontic–surgical treatment helps clini- Fifty-eight patients participated in this The overall OHIP-14 score has a range of
cians to understand what patients have to prospective longitudinal study (28 class 0 to 56, where 0 indicates the best OHR-
endure during treatment and to consider II and 30 class III patients). Ethical ap- QoL and 56 indicates the worst impact of
this when recommending treatment proval for the study was granted by the oral condition on OHRQoL. Before an-
options.10 Many studies have shown a relevant ethics committee. Patients with swering the questionnaire, an orthodontist
correlation between objective orthodontic 4 mm or more reverse overjet were cat- provided the patient with some informa-
indices and patient perceptions of their egorized as class III and those with tion about the study and instructions on
own appearance and oral health condi- +10 mm or more overjet were categorized how to complete the questionnaire and
tion.11,12 OHRQoL is a multifactorial in- as class II. Inclusion criteria were the helped the participant if they had ques-
dex and is thus difficult to measure following: the patient received orthodon- tions. Participants were asked to answer
objectively.13 Tools for the measurement tic treatment prior to surgery via the same all 14 questions in 30 min in a quiet class-
of OHRQoL should be selected based on technique (standard edge-wise, 022 slot room.
the physical, social, and psychological brackets); the patient was scheduled for
domains.14 Condition-specific and generic a combination of a standard one-piece Le
Statistical analysis
measures have been used to evaluate the Fort I osteotomy and bilateral sagittal split
impact of orthodontic–surgical treatment ramus osteotomy (BSSRO) with rigid fix- The Kolmogorov–Smirnov normality test
on patient OHRQoL. Lee et al. reported ation; condylar positioning devices were was performed to determine if the samples
that generic health questionnaires like the not to be applied; an inter-occlusal splint conformed to a normal distribution. Fried-
short-form of the 36-item health survey was scheduled to be used for 2 weeks. man two-way analysis of variance
(SF-36) are not sensitive to the changes in Exclusion criteria were the presence of (ANOVA) was employed to compare
OHRQoL and are not helpful in detecting craniofacial syndromes, cleft lip/palate, changes in OHIP-14 scores at T0, T1,
differences in OHRQoL between individ- and having been scheduled to receive T2, and T3 in each group. The Wilcoxon
uals with and without dentofacial defor- any of the following treatments: distrac- signed-rank test was used to compare
mity.15 tion osteogenesis therapy, genioplasty, or changes in OHRQoL between the time
Condition-specific measures can be maxillary impaction. Patients who had a points T0, T1, T2, and T3. The Wilcoxon
helpful in evaluating disease-related attri- postoperative infection, malunion with signed-rank test was also used to identify
butes and are more sensitive to small but poor occlusion, or a nerve injury were the direction and amount of change during
clinically important changes.16 One of also excluded. the treatment stages by comparing the
these disease-specific measures is the Oral OHRQoL was evaluated at four time level of OHRQoL at T0, T1, T2, and T3
Health Impact Profile (OHIP). Slade and points: prior to treatment (T0), just before in each group. A two-tailed Student t-test
Spencer introduced the original 49-item surgery (T1), at 6 months after surgery was used to compare the means of vari-
OHIP based on Locker’s conceptual mod- (T2), and at 12 months after debonding ables between class II and class III patients
el, derived from the World Health Orga- (T3). The initial evaluation (T0) was car- at the four predefined time points (T0, T1,
nization International Classification of ried out when the patient was referred to T2, and T3).
Impairments, Disabilities, and Handicaps the orthodontic department, before any The magnitude of the statistical differ-
.17 Today, the short form of OHIP (OHIP- treatment was received. In the pre-surgical ence was assessed by calculating effect
14) is used widely and can be employed in stage (T1), patients were examined just sizes. The effect size was calculated by
order to measure dysfunction, discomfort, before surgery (within an average period dividing the mean change by the standard
and disability related to oral conditions.17 of 0.9 years (standard deviation 0.5 years) deviation; the larger the effect size, the
The validity of the Persian version of the after their treatment had been started). In greater the magnitude of the change as a
OHIP-14 was reported by Ravaghi et al.18 the post-surgical stage (T2), patients were result of treatment. An effect size of <0.2
Some longitudinal studies have assessed examined at least 6 months after surgery in was considered minimal, of 0.2–0.49 as
the effects of orthodontic–surgical treat- order to minimize the effects of post-sur- small, of 0.5–0.8 as moderate, and of >0.8
ment on patient OHRQoL using SF-36 and gical complications (oedema, swelling, as large. The level of significance was set
OHIP-14.2,15,19–21 and pain) on the results. In the post-treat- at P < 0.05; a high level of significance
Although, the negative impacts of mal- ment stage (T3), patients were evaluated was indicated by P < 0.001.
occlusion might not be related to its sever- 12 months after removal of the orthodontic
ity,22,23 the negative impacts of deformity appliances.
Results
seem to be related to the type of maloc- To evaluate OHRQoL, the Persian ver-
clusion. There appear to be no reported sion of the OHIP-14 questionnaire,18 Of the 75 adult patients who took part in
studies that have examined the effects of which also included items related to the the study, 28 class II and 30 class III
the type of deformity or Angle classifica- socio-demographic status of the partici- patients completed the OHIP-14 question-
tion of malocclusion on OHRQoL using pants, was used. OHIP-14 includes seven naire at all four time points and were
OHIP-14. The aim of this longitudinal domains (two items per domain): func- eligible for analysis following the appli-
study was to compare changes in OHR- tional limitation, physical pain, psycho- cation of the inclusion and exclusion cri-
QoL in young adults with class II and III logical discomfort, physical disability, teria. Patients in the class III malocclusion
deformities undergoing bimaxillary psychological disability, social disability, group (mean age 21.3  2.7 years)
478 Baherimoghaddam et al.

Table 1. Demographic characteristics of the study patients (N = 58). Changes in physical pain score
Class II, n (%) Class III, n (%) The increase in physical pain score during
Sex T0–T1 was not significant for either class II
Female 16 (57.1) 11 (36.7) patients or class III patients. The physical
Male 12 (42.9) 19 (63.3) pain score decreased significantly during
Education T0–T2 and highly significantly during T0–
Primary/secondary 17 (60.7) 16 (53.3)
T3 in class II patients (Table 4). A signifi-
Tertiary/university 11 (39.3) 14 (46.7)
Age, years, mean  SD 25.1  3.4 21.3  2.7 cant decrease was observed during T0–T2
and T0–T3 in class III patients (Table 5).
SD, standard deviation. Also, class II patients showed a significant
improvement during T2–T3. Differences
were significant between class II and class
III patients at T0 (P = 0.013), T1
were significantly younger than the Changes in the functional limitation
(P = 0.024), and T3 (P = 0.021) (Fig. 2).
patients in the class II group (mean age score
25.1  3.4 years) (P = 0.04). However,
A significant increase in the functional
there was no significant difference be- Changes in psychological discomfort
limitation score, indicating a worsening,
tween the two groups regarding the sex score
was observed during T0–T1 in class II
of the participants (P = 0.543) or their
patients (Table 4) and a significant de- Changes in the psychological discomfort
educational level (P = 0.763). Patient de-
crease was found during T0–T2 in class score showed a highly significant decrease
mographic data are given in Table 1. Sex
II patients and during T0–T2 and T0–T3 in during T0–T2 and T0–T3 in class II
and educational level had no significant
class III patients (Table 5). There was also patients (Table 4) and during T0–T1,
effect on the results of the study. Changes
a highly significant decrease during T0– T0–T2, and T0–T3 in class III patients
in the OHIP domain scores during ortho-
T3 in class II patients. Changes in the (Table 5). Class II and class III patients
dontic–surgical treatment in class II and
mean OHRQoL in class II and class III showed significant differences at T0
class III patients can be seen in Tables 2
patients are shown in Fig. 1. (P = 0.017) and T2 (P = 0.039) (Fig. 3).
and 3, respectively.

Table 2. Comparisons of the mean overall and domain scores during orthodontic–surgical treatment at four time points in class II patients.
T0 T1 T2 T3
OHIP-14 domain P-value
Mean SD Mean SD Mean SD Mean SD
Functional limitation 1.82 1.25 2.61 1.16 0.87 1.01 0.85 0.82 0.014a
Physical pain 2.86 1.18 3.57 1.07 1.61 1.07 1.11 0.95 <0.001b
Psychological discomfort 3.07 2.09 3.81 1.24 1.07 0.82 1.18 1.02 <0.001b
Physical disability 3.15 1.79 3.75 1.07 1.46 1.10 0.86 0.71 0.007b
Psychological disability 2.75 1.51 3.85 1.17 1.24 1.51 0.90 0.89 0.004b
Social disability 3.07 1.53 3.00 1.02 1.25 0.97 1.04 0.88 <0.001c
Handicap 2.46 1.35 2.25 1.23 1.14 0.65 0.93 0.72 0.011a
Overall OHIP-14 19.18 2.97 22.84 3.40 8.64 3.21 6.87 2.11 <0.001c
OHIP, Oral Health Impact Profile; SD, standard deviation; T0, baseline; T1, just before surgery; T2, 6 months after surgery; T3, 12 months after
debonding.
a
Significant at the level P < 0.05 (Friedman two-way ANOVA).
b
Significant at the level P < 0.01.
c
Highly significant at the level P < 0.001.

Table 3. Comparisons of the mean overall and domain scores during orthodontic–surgical treatment at four time points in class III patients.
T0 T1 T2 T3
OHIP-14 domain P-value
Mean SD Mean SD Mean SD Mean SD
Functional limitation 1.53 0.82 2.13 1.33 0.80 0.83 0.81 0.78 0.005b
Physical pain 1.47 0.86 1.70 1.06 0.83 0.65 0.80 0.66 0.040a
Psychological discomfort 5.23 1.07 3.23 1.01 1.00 0.95 0.93 0.87 <0.001c
Physical disability 1.30 0.75 2.07 1.01 0.80 0.71 0.77 0.75 0.020a
Psychological disability 4.33 0.88 3.63 0.96 1.01 0.88 0.97 1.03 <0.001c
Social disability 3.03 1.13 2.50 1.48 1.07 0.83 0.93 0.74 <0.001c
Handicap 2.97 1.07 2.37 0.75 1.20 0.81 1.03 0.85 <0.001c
Overall OHIP-14 19.86 2.57 17.63 3.83 6.71 2.45 6.24 2.66 <0.001c
OHIP, Oral Health Impact Profile; SD, standard deviation; T0, baseline; T1, just before surgery; T2, 6 months after surgery; T3, 12 months after
debonding.
a
Significant at the level P < 0.05 (Friedman two-way ANOVA).
b
Significant at the level P < 0.01.
c
Highly significant at the level P < 0.001.
QoL and orthodontic–surgical treatment 479

Table 4. Comparisons of oral health-related quality of life from baseline (T0) to pre-surgery (T1), 6 months after surgery (T2), and 12 months after
debonding (T3) in class II patients.
OHIP-14 T0–T1 T0–T2 T0–T3 T2–T3
domain
Effect Effect Effect Effect
Mean SD P-value size Mean SD P-value size Mean SD P-value size Mean SD P-value size
Functional +0.78 1.75 0.024a 0.45 0.96 1.50 0.004b 0.64 0.97 1.25 <0.001c 0.8 0.02 0.98 0.808 0.40
limitation
b c b
Physical pain +0.91 1.86 0.050 0.39 1.25 1.65 0.001 0.75 2.04 1.75 <0.001 1.17 0.50 1.17 0.003 0.67
Psychological +0.64 2.47 0.182 0.26 2.00 2.24 <0.001c 0.89 1.89 2.11 <0.001c 0.90 +0.11 1.47 0.853 0.07
discomfort
Physical +0.86 2.21 0.044a 0.31 1.43 2.10 0.002b 0.68 2.04 1.89 <0.001c 1.08 0.61 1.37 0.028a 0.45
disability
a b c
Psychological +1.10 1.87 0.010 0.53 1.51 2.50 0.001 0.64 1.85 1.61 <0.001 1.13 0.34 1.69 0.631 0.12
disability
Social +0.07 1.90 0.828 0.03 1.83 1.66 <0.001c 1.10 2.04 1.80 <0.001c 1.13 0.21 1.17 0.365 0.18
disability
Handicap +0.21 1.34 0.384 0.17 1.32 1.44 <0.001c 0.91 1.54 1.35 <0.001c 1.14 0.21 0.83 0.175 0.25
Overall +3.71 4.32 0.002b 0.86 10.40 6.43 <0.001c 1.62 12.36 5.57 <0.001c 2.21 1.99 3.99 0.942 0.49
OHIP-14
OHIP, Oral Health Impact Profile; SD, standard deviation.
a
Significant at the level P < 0.05 (Wilcoxon signed-rank test).
b
Significant at the level P < 0.01.
c
Highly significant at the level P < 0.001.

Table 5. Comparisons of oral health-related quality of life from baseline (T0) to pre-surgery (T1), 6 months after surgery (T2), and 12 months after
debonding (T3) in class III patients.
OHIP-14 T0–T1 T0–T2 T0–T3 T2–T3
domains
Effect Effect Effect Effect
Mean SD P-value size Mean SD P-value size Mean SD P-value size Mean SD P-value size
Functional +0.60 1.52 0.044 0.39 0.73 1.21 0.005b 0.05 0.80 1.21 0.002b 0.66 0.01 1.06 0.960 0.09
limitation
Physical pain +0.23 1.41 0.435 0.16 0.63 1.16 0.011a 0.54 0.67 0.96 0.001b 0.69 0.03 0.85 0.855 0.03
Psychological 2.00 1.51 <0.001c 1.32 4.23 3.45 <0.001c 1.22 4.30 3.37 <0.001c 1.27 0.07 1.26 0.668 0.05
discomfort
Physical +0.77 1.48 0.013a 0.52 0.50 0.97 0.010a 0.51 0.53 1.14 0.013a 0.46 0.03 0.56 0.739 0.05
disability
Psychological 0.70 1.37 0.014a 0.51 3.32 2.85 <0.001c 1.13 3.36 2.98 <0.001c 1.15 0.20 1.27 0.950 0.16
disability
c c
Social 0.53 1.90 0.121 0.27 1.97 1.80 <0.001 1.06 2.10 1.44 <0.001 1.46 0.13 1.01 0.572 0.13
disability
Handicap 0.40 1.40 0.127 0.29 1.77 1.59 <0.001c 1.11 1.93 1.28 <0.001c 1.50 0.17 0.95 0.325 0.18
Overall 2.03 4.85 0.029a 0.44 13.03 10.25 <0.001c 1.27 13.76 7.87 <0.001c 1.98 0.73 3.04 0.227 0.24
OHIP-14
OHIP, Oral Health Impact Profile; SD, standard deviation.
a
Significant at the level P < 0.05 (Wilcoxon signed-rank test).
b
Significant at the level P < 0.01.
c
Highly significant at the level P < 0.001.

Changes in physical disability score Changes in psychological disability Changes in social disability score
score
A significant increase in physical dis- Class II patients showed an increase in
ability score was observed during T0– A significant increase in psychological social disability score during T0–T1 but it
T1 in class II and class III patients. disability score during T0–T1 and a sig- was not significant. They also showed a
During T0–T2 and T0–T3, physical nificant decrease during T0–T2 and T0– highly significant decrease during T0–T2
disability scores decreased significantly T3 were recorded in class II patients (Ta- and T0–T3 (Table 4). In contrast, during
in both class II and class III patients ble 4). Class III patients showed a constant orthodontic–surgical treatment in class III
(Tables 4 and 5). Significantly higher decrease during treatment, which was sig- patients, a non-significant decrease was
physical disability scores were found nificant during T0–T1 and highly signifi- observed during T0–T1 and a highly sig-
at T0 (P = 0.004), T1 (P = 0.029), cant during T0–T2 and T0–T3 (Table 5). nificant decrease during T0–T2 and T0–
and T3 (P = 0.044) in class II Significantly higher scores were recorded T3 (Table 5). The difference was signifi-
patients compared to class III patients at T0 in class III patients (P = 0.031) cant between class III and class II patients
(Fig. 4). (Fig. 5). at T1 (P = 0.024) (Fig. 6).
480 Baherimoghaddam et al.

Fig. 1. Changes in the functional limitation score in class II and class III patients from baseline (T0) to pre-surgery (T1), 6 months after surgery
(T2), and 12 months after debonding (T3).

Changes in handicap score recorded during T0–T2 and T0–T3 in both Changes in overall score
class II and class III patients (Table 4 and
The handicap score remained relatively
5). A significantly higher score was found Both class III and class II patients
unchanged during T0–T1 in both groups;
at T0 in class III patients compared to class showed a decrease in the overall
however, a highly significant decrease was
II patients (P = 0.018) (Fig. 7). score following orthodontic–surgical

Fig. 2. Changes in the physical pain score in class II and class III patients from baseline (T0) to pre-surgery (T1), 6 months after surgery (T2), and
12 months after debonding (T3).
QoL and orthodontic–surgical treatment 481

Fig. 3. Changes in the psychological discomfort score in class II and class III patients from baseline (T0) to pre-surgery (T1), 6 months after
surgery (T2), and 12 months after debonding (T3).

treatment. However, class II patients stage in class III patients. Changes (Tables 4 and 5). Differences between
showed a significant increase in the over- in the overall score showed a highly class II and class III were significant at
all score during T0–T1; in contrast, significant decrease during T0–T2 and T1 (P = 0.003) and T2 (P = 0.008)
the overall score decreased during this T0–T3 in class II and class III patients (Fig. 8).

Fig. 4. Changes in the physical disability score in class II and class III patients from baseline (T0) to pre-surgery (T1), 6 months after surgery (T2),
and 12 months after debonding (T3).
482 Baherimoghaddam et al.

Fig. 5. Changes in the psychological disability score in class II and class III patients from baseline (T0) to pre-surgery (T1), 6 months after surgery
(T2), and 12 months after debonding (T3).

Discussion health should be taken into consideration possible effects of treatment on their quality
as well.7–9 It is important to evaluate the of life during and after treatment.
Aesthetic and functional improvements are impact of different stages of orthodontic– In the present study, class III patients
not the only aims of orthodontic–surgical surgical treatment on patient OHRQoL were younger than class II patients. The
treatment; the patient’s psychological in order to educate patients regarding the lower mean age of the class III patients

Fig. 6. Changes in the social disability score in class II and class III patients from baseline (T0) to pre-surgery (T1), 6 months after surgery (T2),
and 12 months after debonding (T3).
QoL and orthodontic–surgical treatment 483

Fig. 7. Changes in the handicap score in class II and class III patients from baseline (T0) to pre-surgery (T1), 6 months after surgery (T2), and 12
months after debonding (T3).

might be due to the psychosocial pressure their appearance compared to class II consistent with those of other studies
of this type of malocclusion, which neces- patients.24 The results of the present study that have found no association between
sitates earlier treatment seeking. Patients did not show any significant differences in sex and OHRQoL.19,25,26 However,
with class III malocclusion have been the results obtained from all approaches Nicodemo et al. observed that male
shown to be significantly less happy with between the two sexes; this finding is patients showed greater improvement in

Fig. 8. Changes in the overall score in class II and class III patients from baseline (T0) to pre-surgery (T1), 6 months after surgery (T2), and 12
months after debonding (T3).
484 Baherimoghaddam et al.

the vitality domain of the SF-36 and counterparts among whites.28 Some defor- postoperative stage. These findings are
females showed greater improvement in mities may be less troublesome due to especially useful for educating patients
the emotional domain.20 their higher incidence in society; approxi- about what to expect in the pre-surgical
The present data showed significant mately 15% of untreated adolescents in and post-surgical stages of treatment and
improvements in all seven domains of the USA have a class II malocclusion. to help them overcome the negative tem-
the OHIP-14 in both groups after ortho- Class II deformities are more prevalent porary effects of treatment.
dontic–surgical treatment. These results in white populations than class III, thus
are in agreement with those of other stud- they might impose less of a social burden
Funding
ies showing that orthodontic–surgical on the individual because of the appear-
treatment does have functional, aesthetic, ance. In class III patients, although the All authors disclose no financial or per-
and psychological benefits.19,20 In con- required pre-surgical decompensations sonal relationships with other people or
trast, Rustemeyer and Gregersen reported have more untoward side-effects on the organizations that could inappropriately
that physical limitation, pain, and chewing appearance, the mere presence of the or- have influenced their work.
function did not change after surgery, and thodontic brackets on the teeth is evidence
improvements in psychological and aes- of ongoing treatment and can help the
Competing interests
thetics aspects were higher than the func- patient to overcome their psychological
tional aspect following surgery.2 problems.28 No competing interests exist.
Although significant improvements in In the post-surgical stage, both groups
OHRQoL were observed in both groups experienced significant improvements in
Ethical approval
during and after orthodontic–surgical all seven domains of the OHIP-14. How-
treatment, the pattern of change was dif- ever, those with a class III deformity Ethical approval was obtained from the
ferent in the two groups. The psychologi- showed more significant changes in the Ethics Committee of Shiraz University of
cal and personality profiles of skeletal domains concerning appearance and psy- Medical Sciences (#90-01-03-3887).
class II and class III patients and how they chological issues, such as psychological
are perceived by their relatives and friends discomfort, psychological disability, and
Patient consent
are different.20 Class III deformity engen- social disability, rather than the domains
ders more psychological and inter-person- related to functional limitation and physi- Not required.
al problems due to the alterations in soft cal pain. The results of this study are
tissue aesthetics.10,27 Although, Choi et al. consistent with the findings of Nicodemo
Acknowledgements. The authors appreci-
claimed that no significant difference was et al., who showed that vitality, social
ate the cooperation of Dr Mehrdad
observed in the level of OHRQoL among function, and emotional function changed
Vosough for his help with the statistical
patients with different deformities during more significantly than physical health
analyses.
treatment,19 Gerzanic et al. reported that after surgery in class III patients.20
patients with class II and class III maloc- In this study, the changes in OHRQoL
clusion showed significant differences in were evaluated 1 year after the completion
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