"DIABETES"
A Summary submitted (6 the Bundelkhand Univereily in
paiial fulfillment for the award. of the degtoe, of
Bachelor in Microbiology
fewer
DEPARTMENT OF MICROBIOLOGY
BUNDELKHAND UNIVERSITY, JHANSI
(U.P) INDIA
2022
UNDER THE SUPERVISION OF
SUBMITTED TO:- SUBMITTED BY:-
Dr. Pratibha Arya Shaivya Bajpayee
(Professor in Food, Microbiology
Health and hygiene) 1st-SemesterACKIOLMLEDGEMENT
Lamvery grateful to all those whe have helped me, as
AT have Baished oy project on toe and eFfectuely, tn
all keumility ard appreciation, Lam everwkeloed to
recognize my abpth to ail those who have helped me to
bring those tdeas into good ase,
Taoudd like to thank oy teacher Mes Pratibha Arya
too, She managed to ye me suppor? and
excouragement and directed ov. on differen? topies,
Ard with the aid Skom her helpful adbice, Seedback,
and metwation t kecame able Fo execute these projec?
actwities,
hast but not least, Lalso want to thank my Friends
ake helped a lo? to gather dierent details, gather
information, or dvect? me to form immediately to
sake this project. Gwen their hectic schedules, they
offered me various designs to kelp this project special.DIABETES
Diabetes: An Overview :-
FS you have djabetes, your body isa'? able to property
process ard use glucose from the Sood you eat.
“here are bt SStreat types of chaketes, each with
ASSevent causes, but they all shave the common
problem of having Poo muck glucose in your
bloodstream, Theatments include medications
and/or insulins. Some types of chabetes can be
prevented y adopting a healthy Usestyle,
Whatis chabetes?
Diaketes happens when your body isn't able to take up
sugar Cylucose? into és cells and use it for energy.
this results in a build up of extra sugar in your
Moodstream.
Mismanagement of dhabetes can lead to serious
CONSEQUERCES, CAUSING damage To a wick range oF
your boal's ovgans and tissues — including your
deart, kidneys, eyes and nerves.
Why ts ay blood glucose level high? Now does tis
Aappen?The process of digestion includes breaking dowa the
Sood! you cat into various deren? autrieat
sources. Whea you cat carbohydrates (Sor example,
bread, rice, pasta, your body breaks tis dewa iate
sugar (glucose, When glucose is ia your
Koodstream, rt aceds kelp — a” hey” — to ge? into res
Siad okstination where i? 8 used, kick is tastae your
boat's cells Cealls make up your booy’s tissues acct
organs), Tis kelp ov "hey? is iasalia,
dasuliais akormonc mack by your pancreas, an
organ located bekind your stomach, Your pancreas
releases tasulia tate your Moodstream, Insulin acts
as the “hey” that unlocks the cell wall “ober,” which
allows glucose to cater your boay's cells, Glucose
prowraes the “fuel” or energy tssues and organs
need to properly function.
AS you have chabetes:
Your pancreas doe sa’? make. any insula or enough
rasalia,
Or
Your pancreas makes iasulia but your booly "5 cells
clon’? respond to and can’? use ft as it normally
heute!A¥ glucose can’t get into your body's cells, rt stays
fa your Meodstream and your Mood! glucose level
rises.
What are the abSSereat types oF chabetes?
The types oF chabetes are:
“Type | ofabetes: This type ts an autotomune
disease, meaning your beay attacks self. In this
cast, the iasalia-preduciag cells ta your pancreas
are destroyed. Up to 1O% of people who have ahabetes
have Type. 20's usually chagnosed ia childern and
young adults Chat can aevelop at any age. £8 was
once better haown as “juvenile” ctabetes, People with
Type | ofabetes aced to take iasalia every olay. This
8 why itis also called iasulia-aependent afabetes.
Type 2 chabetes: Lirth this type, your bool either
dbesa’t make enough insulin or your body's cells
doa’? respond aormally to the iasulia, This is the
most common type of chabetes, Up to 15% of people
arth ohabetes have Type 2. 2% usually cccars ia
attdlehe- aged and older people, Other common names
Sor Type 2 tacluat aolult-onser dtabetes and
tasulta-resistant dhabetes, Your parents or
granoparents may have called 1 “having a touch of
Sadar.Prechabetes: This type is the stage before Type 2
dhabetes. Your beod glucose levels are higher than
normal but aot kigh encagh to be of Flerally chagaosed
arth Type 2 habetes.
Gestational chabetes: This type okvelops ta some.
women during ther pregnancy, Gestational ohabetes
asually goes away after pregnancy. Nowtever, £ you
fave gestational chabetes you're at higher rish oF
akveloping Type 2 chabetes later on ta tS.
tke gets ctabetes? What are the rsh Saetors?
Factors thet increase your rish df¥er alepeaatag oa
the type of dhabetes you ultimately akvelop.
Fish Seetors Sor Type | chabetes include:
Having a Family history Caveat or sibliag> of Type
| ofaketes.
Anjury to the panceeas (such as by inktetion,
tumor, surgery or accident,
Presence of aatoantibootes Cantibodies that
aistakenly attach your owa body's issues on
organs),
Plysical stress Csuck as surgery or illaess>.
Exposure to illnesses caused by viruses,Fish Seetors Sor preatabetes and Type 2 chabetes
aclu:
Fantly history Cparect or sibling? of prectabetes or
“Type 2 chaberes.
Being Bleck, Mspanic, Nate American, Asian-
American race or PaciSe Estander.
Maving orerwcight/ obesity.
Wavicg kigh Hood pressure,
-Maving low NDE cholesterol Che. “good!” cholesterol
and high triglyceride level.
Being physteddly inactve.
Being age 45 or olakr,
Maing gestational chaberes or giviag birth to « baby
weighiag more than 9 pounds,
Maving pelyeystie ovary syndome,
Having @ history of kear? abscase or stroke,
Being a smoker,
Fish Sectors Sor gestational atabetes taclaak:
Fantly history Cparect or sibling? of prectabetes or
“Type 2 dhaberes.
Being ASttean-American, Mspanic, Native American
or Asian-American,
~Meving overweight! obesity before your pregnancy,
a ne eeWhat causes habertes?
The cause of chabetes, regaraless of the type, iS
having too muck glucose circulating ia your
Koodlstrean. Nowever, the reason why your Mood
glucose levels are high ders alpeactag oa the type
oF ahabetes,
Causes of Type | dhabetes: This is an immune.
system akscase, Your body atiachs and destroys
fasulia-produciag cells ia your pancreas. Wrtkout
tasulia to allow glucose to enter your cells, fucose
baildls up ia your Moodstream, Genes may alse play a
role ia some patents, Also, a virus onay tigger the.
tomune system attack,
Cause of Type 2 chabetes and preataberes: Your
body's cells clon’? allow insulin to work as rt should
to let glucose into tts cells. Your body’ s cells kave
become resistant to insulin. Your pancreas can’?
4eep up and make enough iasulia to overcome tis
resistance, Glucose levels rise ia yout bloodstream,
Gestational ohabetes: Normones produced by the
placenta during your pregnancy make your body's
cells more resistant to insulin. Your pancreas can't
make enough tasulia to overcome this resistance.
The puck glucete remains tn your bloadsébvean.What are the symptoms of dhabetes?
Symptoms of ctabetes tacluae:
increased thirst.
Weak, tired Seliag.
Blurred vistoa.
Nambress or tagliag ta the hands or Set,
Slow -healiag sores or cuts.
Unplanned weight loss.
Freguent ariaeton,
Freguert unexplained taftetions.
Dry mouth,
Other symptoms
ta women: Dey and iteky shin, and Sreguent yeast
taftetions or urinary tract iastctions.
da men: Beereased sex dee, erectile dysfunction,
decreased muscle strength.
Type | ofabetes symptoms: Symptoms can develop
guichly — over a few weeks or months, Symptoms
begin when you're young — as a child, teen oF young
adult, Aabitional symptoms include nausea, vomiting
or stomach pains and yeast infections om ariaaty
tract taseetions.Type 2 chaketes anc prectabetes symptoms: You. may
not have any symptoms at all or may ner notice Them
since they ckvelop slouly over several years.
Symptoms usually kegin 70 develop when you. ‘re an
adlul?, but prectabetes and Type 2 chaketes is on The
rise in all age groups.
Gestational ohabetes: You typically all no? notice
symptoms. Your obstetrician all Fes? you Sor
gestational chaketes ketween 24 and 2% weeks of
your pregnancy.
Now is dlaketes managed?
Diaketes afSte?s your whole body. To bes? manage
dhahetes, you'll need to take steps to manage your
risk Suetors, including:
Heep your Mood glucose levels as near to normal as
possible by Sblloaxng a ate? plan, taking prescribed
medtcation and. lacreasing your actwity level,
Meinrain your ood cholesterol CMDL and kdk
levels) andl Friglgeericte levels as near the normal
ranges as pos site.Diagnosis and treatment
Early chagrosis can be accomplished trough relatuely
inexpensite testing of blood glucose,
“Theatment of diabetes imotves diet and plysical
acturly dong with lowering of Heed glucose and the
laels of other known rish Sectors that damage blood
vessels, Tohaces use cessation is also important to
atcid complications.
Anrterventions that are both cost-saving and Feasible
in low- and middle-income countries include:
-Hood qlacose control, particalarly in type | dabetes,
People a¥th type | chaketes reguire insulin, people with
type 2 chaketes can be treated with oral medication,
Lat may alse reguire insali
blood pressure control; and
foot care (patient self-care by maintaining Soot
Aygiene} wearing appropriate Footwear; seeking
professional care Por alee managements ard regular
examination of Stet by health professionals),PREVEN-TIONS:
ikestyle measures have heen shown to he e$eetive in
preventing or delaying the onset of type 2 chaketes.
To help preven? Fype 2 dhaketes and rts complications,
people should:
-ackieve and maintain a healthy bocly weigh?)
~te physically actwe ~ doing at leas? 3O minutes of
regular, moderate-intensity activity on most etays.
More actuity is reguired Sor weigh? controls
~eat a healthy det, avoiding sugar and saturated
Sais; and
-avoid tobacco ase ~ smoking increases the rish of
diabetes and cardiovascular disease,