Siddharth Vats,

Chapter 1 - Methods for Extractions of Value-Added Nutraceuticals From

Lignocellulosic Wastes and Their Health Application,
Editor(s): Alexandru Mihai Grumezescu, Alina Maria Holban,
In Handbook of Food Bioengineering,
Ingredients Extraction by Physicochemical Methods in Food,
Academic Press,
2017,
Pages 1-64,
ISBN 9780128115213,
https://doi.org/10.1016/B978-0-12-811521-3.00001-6.
(https://www.sciencedirect.com/science/article/pii/B9780128115213000016)
Abstract: Extraction, the term, is used for the separation of medicinally valuable
phytochemicals, nutraceutical functional foods, fruit purees and powders,
biochemicals, electrolyte blends, health-promoting agents, nutritive oils,
antimicrobial products, bioactive compounds, commercially valuable food flavoring,
and additive compounds of biochemical nature, proteins, nutritional supplements,
personal care and cosmetic, drugs and pharmacophores from eukaryotic and
prokaryotic cultured cells or from plants, animals, and microbes directly by using
standard physical extraction procedures and solvents. The products obtained in
these extracts are relatively impure solutions, semisolids, or dried powder for
oral use. Various physical and chemical methods of extraction are employed
individually or synergistically for the extraction of desired bioactive
ingredients. For industrial scale, like for the use of biorefineries, mathematical
modeling optimized extraction methods are more suitable because they make a process
more cost effective and efficient. For creating a suitable optimized model of
physicobiological parameters, statistical methodologies, such as response surface
methodology (Box Benkhen Design, Central Composite Design) and artificial neural
network (ANN), have been preferred because of their proven advantages. ANN and
response surface methodology (RSM) combine mathematical and statistical techniques
for analyzing problems, with several independent variables having a control on a
dependent variable.
Keywords: extraction; value-added products; nutraceuticals; phytochemicals