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Last edited: 8/5/2022

PHARMACOKINETICS | DRUG METABOLISM


Pharmacokinetics | Drug Metabolism Medical Editor: Ilia-Presiyan Georgiev

I) REVIEW QUESTIONS WITH ANSWERS

QUESTIONS ANSWERS

1) How are metabolites NOT excreted? b) Through shedding of epithelial cells


a) Into the feces
b) Through shedding of epithelial cells
c) Into the urine
d) Through breathing

2) Which reaction is NOT part of phase I d) Sulfation


biotransformation?
a) Oxidation
b) Reduction
c) Hydrolysis
d) Sulfation

3) Which drug is a CYP450 inhibitor? a) Ritonavir


a) Ritonavir
b) Phenytoin
c) PHB
d) Carbamazepine

4) Which drug is a CYP450 inducer? a) Carbamazepine


a) Carbamazepine
b) Erythromycin
c) Ritonavir
d) Omeprazole

5) Which reaction is NOT part of phase I c) Phosphorylation


biotransformation?
a) Methylation
b) Glutathionylation
c) Phosphorylation
d) Glucuronidation

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