Lab Partner. Pan Kin Student ip;_2!#"" CHEM 162 LAB #6: SYNTHESIS OF ASPIRIN Goals of this lab: ® Synthesize aspirin and evaluate the product for purity and yield * Perform stoichiometry calculations to determine expected yield vs. percent yield * Apply Beer's law to determine the amount of impurity in the crude product * Compare melting points of the crude product and pure aspirin to evaluate determine relative Purity of the product Your lab report will be grade on the following criteria using a poor/good/excellent rating system: * Calculations are accurate and complete based on data gathered; proper significant figures and units are used * Data collected is reasonable; measurements are careful and accurate Conclusions are reasonable and logical * Lab report is completed neatly with organized responses and legible handwriting Vivana ¥. Signature: ee eee ee eS This lab is worth 60 points: 10 points for notebook pages fo points for the lab report (Do NOT include your notebook pages when you scan your report for upload into Gradescope.)NAME. Yionnd Yn Quiz Section_}< NEATLY show your work. Use a reasonable number of significant figures, include units with your data, and keep your answers concise. Part |. Synthesis of Aspirin Table 1 = Value Units Mass of salicylic acid o-uy 3 Volume of acetic anhydride ots wh Volume of phosphoric acid 2 dispy Temperature of reaction bie §2 eZ Mass of filter paper + watch glass 18843 3 Mass of filter paper+ watch glass +crude | - | | product 9.041 La | Part | Calculations and Results 1. Calculate the actual yield of crude aspirin product. Neatly show your work. Odnat Nels MW DOF Peta rmbt — (mpeg poy gia) o [th 14-14 = ol4§9 Calculation summary: How much crude aspirin did you produce? CM) 2. The procedure requires that acetic anhydride reactant be present in excess. Demonstrate that this is the case with your reaction by providing a stoichiometry calculation using your data and the density of acetic anpydride (1.082 g/ml). For full credit, be sure to show all of the required work and explicitly &Smpare the amounts of reagents used. ers of ote ambhe = Lona cont aot 9 |r] Yehay mays ~]02 votginal ANT J larozg hel 2 9.09509 vol. Seep 2/38 Legal - OUT FL 3B gel > ose orgy wl 9s dong 0905S wm) —, ovegeg ~eetlsh > cnee3y3 wl 2 Sateyey Geet ialinting veal. Page 2 of 5— 3._In the following table, copy the required values from page [_Mass of salicylic acid (Table 1) oueg Actual yield (Qt) | 0. |age) | ‘Assume that your product is pure aspirin and calculate the percent yield you achieved. Forfull { credit, be sure to neatly show all of the required work. arya» ee reel oa Xlhs oar, ¢ Tenet nays 9:09 8 Atopy agit apace ALPE 180-163 bo] = 0.2814 4A Calculation summary: What is the % yield for your synthesis reaction? Part ll, Determination of % Salicylic Acid Table 2. a Value Units Mass of crude aspirin product analyzed 9.01% a Volume of 95% ethanol wi Volume of 0.025 M iron(Ii!) nitrate solution I ml Total volume of iron(ttt)-salicylate solution See | HL Wavelength for absorbance measurement su ean en Pathlength of sample analyzed I Gy Molar extinction coefficient -— ton? Absorbance (1* measurement) ott Absorbance (2! measurement, if applicable) If your first Absorbance measurement is >1.5, then a dilution is required. In this box, provide the details of your dilution. Page 3 of 5NAME. Yea Quiz Section Ac Part Ii Calculations and Results 4._In the following table, copy the required values from Part I Table 2: Absorban’e na | Mass of crude product analyzed [any Calculate the % salicylic acid in your product. For full credit, be sure to neatly show all ofthe required work. : Kzac 9 4Hg 2 YOn'O in C. ste Cy Ae > 4D Hom y © 4a sormy UML > gee 4 Dx[o%m KOE F-7pant ol Salen A Lo ¥nole DENG = f o-ooehr 200) se Oleh 27h Calculation summary: What is the % impurity in your product? DUP 5._In the following table, copy the required MASS values from pages 2 and 3: Yield of crude product (Pt1a1)| 9.1964 Theoretical yield (Pt103) | 9.28 }4 Given your new knowledge of the % impur Neatly show your work, Clee rant) X @- Tey > og 1 = Aly ee (Mh ey les feore ies rity of your product, calculate the corrected % yield. *= £6371 Calculation summary: What is the corrected % yield for your synthesis reaction? _ 65°37 f+ §. What factors contribute to the % yield being high/low? The 4 BD low beooge we colt SSeS uf de Seuple fon 3 int MES Gingie we Wtighel — Wwe Gulf Ee an oe patel de dle oy fom Fey , Page 4 of 5ae aenaim. This) Part ill. Melting Point Determination Table 3. | Range : units | Trial #1 for crude aspirin sample | BB [343 Trial #2 for crude aspirin sample exes | © Pure aspirin sample NY typ - Part il! Results and Discussion 7. Compare and contrast the melting points observed for your sample and the pure aspirin sample. How would you expect the data for your product to differ from the pure compound? Does your data follow that prediction/expectation? dy TY The elt Je alr pertes iy PP beth, Some OYE (we an eB peltig Prt He ue opin Saryle. TM) Ly Contech fovy glean The Pe eupiin as Gh farts Fave) lan Heme IE” Thay me degen Stomp IRF WAH In hiperee neti PE leoag i daly ane Oat dy baat Pag. boa The rae sample bas ley go anh or iY ipa. Page 5 of 5