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CLINICAL RESEARCH

Evaluation of the intaglio surface shape of implant-supported


complete-arch maxillary prostheses and its association with
biological complications: An analytical cross-sectional study
Francine Baldin Able, MSD,a Nara Hellen Campanha, PhD,b Ibrahim Abazar Younes, DDS,c and
Ivete Aparecida de Mattias Sartori, PhDd

The rehabilitation of edentu- ABSTRACTS


lous patients with implant-
Statement of problem. Whether the shape of the intaglio surface of fixed implant-supported
supported prostheses has maxillary prostheses is associated with the occurrence of biological is unclear.
been reported to provide a
successful treatment with high Purpose. The purpose of this cross-sectional study was to evaluate the shape (convex or concave)
rates of survival for both im- of the intaglio surface of complete-arch implant-supported maxillary fixed prostheses and to assess
the association with biofilm accumulation, hyperemia, bone loss, and patient satisfaction.
plants and prostheses.1-4 The
prosthesis can be fixed or Material and methods. Study participants consisted of 56 individuals with fixed complete implant-
removable,5-8 according to the supported maxillary prosthesis attending follow-up appointments. The 56 prostheses supported by
needs of each patient.7,9,10 388 implants had been in place for an average of 5.5 years (range 1-14 years). The intaglio surface
was divided into areas corresponding to the cantilever regions and between implants (n=442)
However, anatomic factors,
and was assessed for shape (concave or convex) and biofilm index (0 to 3). Tissue hyperemia
the ability to carry out hygiene, (redness) was assessed as absent or present. Bone loss (mm) was measured from digital
patient expectations, and periapical radiographs by 2 calibrated evaluators (kappa=94.9%). Study participant satisfaction
financial commitments must was investigated by using a visual analog scale. Association assessments (a=.05) between the
be considered.3,5,6 Hygiene shape of each area and all these parameters were performed with the Friedman, linear
procedures are easily per- regression, and logistic regression tests.
formed for removable pros- Results. Of the analyzed areas, 58 (13.1%) were concave, and 384 (86.9%) were convex. Biofilm was
theses, but for fixed prostheses absent on 3.5% of the concave and 5.5% of the convex areas. Biofilm was detectable with a probe
the ease of cleaning varies on 12% of the concave and 22.4% of the convex areas and clinically visible in 58.6% of the concave
with the prosthetic design.5,6 and 57.8% of the convex areas. Abundant biofilm was seen in 25.9% of the concave and 14.3% of
Phonetic changes, contours the convex areas and was associated with hyperemia (P=.003). A statistically significant association
that make cleaning difficult, was found between the shape and biofilm accumulation (P=.009). Hyperemia was present in 199
(45%) areas. The association analysis between the shape of the area and the presence of
and biological complications
hyperemia was not significant (P>.05). The mean bone loss was 0.71 mm (0.91 mm). Implants
have been reported for placed near concave areas underwent greater bone loss (P=.001). Study participants reported a
complete-arch implant-sup- high level of satisfaction with the esthetics, mastication, speech, and smile provided by the
ported maxillary prosthe- prosthesis, with satisfaction scores ranging between 8.46 and 8.77. However, in relation to ease
ses.3,11 If a significant space is of cleaning, only 19.6% were fully satisfied.
provided between the base of Conclusions. The shape of the intaglio surface of prostheses influenced the occurrence of biofilm
the prosthesis and the mucosa, accumulation and bone loss, and concave areas showed greater biofilm accumulation and bone
air and saliva can escape, resorption. High rates of satisfaction with treatment were identified. (J Prosthet Dent 2022;128:174-80)

Supported in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001.
a
Postgraduate student, PhD Program in Dentistry, General Dentistry Area, State University of Ponta Grossa (UEPG), Ponta Grossa, Brazil.
b
Professor, MSD and PhD Program in Dentistry, General Dentistry Area, State University of Ponta Grossa (UEPG), Ponta Grossa, Brazil.
c
Postgraduate student, Masters Degree Program in Dentistry, Implantology Area, Faculdade ILAPEO, Curitiba, Brazil.
d
Professor, MSD and PhD Program in Dentistry, Implantology Area, Faculdade ILAPEO, Curitiba, Brazil.

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August 2022 175

Clinical Implications
Knowing the impact of the intaglio surface shape of
implant-supported fixed prostheses on the behavior
of soft and hard peri-implant tissues is important for
clinicians to be able to determine the most
appropriate form and to help patients perform
hygiene procedures correctly and attend periodic
follow-up appointments.

impeding phonetics. However, reducing this space


makes it more difficult to perform hygiene procedures.11
Controlling biofilm accumulation is essential to reduce Figure 1. Representative prosthesis with demarcation of intaglio areas
the incidence of peri-implant disease,12 since poor oral identified; in this example 7 areas. Red lines show difference in length of
hygiene is a risk factor for the development of mucositis areas.
and peri-implantitis.13,14 Access to hygiene can be
planned in implant-supported prostheses15 that have a
and 2018, who had attended follow-up appointments,
convex shape and a smooth and polished surface.16,17
and who had consented to be part of the research. All
The intaglio surface of an implant-supported pros-
prostheses were a combination of resin and metal. The
thesis rehabilitating an edentulous maxilla should not
metal bar was cast in cobalt-chromium alloy to cylinders
have concavities, porosities, or a flange but should have a
using the passive fit cementation technique.23 The in-
convex profile with minimal contact with the mucosa to
taglio surfaces in contact with soft tissue were made of
enable the use of dental floss and interdental brushes.18-
20 heat-polymerized acrylic resin, and the denture teeth
In addition to the intaglio surface contour, the distance
were made of acrylic resin. Exclusion criteria included the
between implants also affects hygiene access; implants
presence of segmented, cemented, or metal-ceramic
that are close together impede biofilm control.12 For
prostheses.
treatment to be successful with few complications, reg-
The study assessed the association between the shape
ular professional follow-up and self-performed hygiene
of the intaglio surface of maxillary implant-supported
procedures are essential.2,6,21,22
prostheses and biofilm accumulation, hyperemia, and
Information on how the shape of the intaglio surface
bone loss and also measured study participants’ satis-
of complete-arch implant-supported prostheses affects
faction with the rehabilitation. The data were obtained
treatment outcomes is scarce. Therefore, the objective of
during follow-up appointments carried out between May
the present study was to assess the association of the
and September 2019. These appointments were part of a
intaglio surface of the prosthesis (concave and convex)
follow-up program established 14 years earlier for pa-
with biofilm accumulation, bone loss, and hyperemia and
tients rehabilitated with osseointegrated implants at
to assess patient satisfaction with maxillary complete-
ILAPEO College. During the appointment, the prosthesis
arch implant-supported fixed prostheses. The null hy-
was removed for clinical evaluation of the condition of
potheses were that the presence/abundance of biofilm,
the peri-implant tissues, the prosthesis, the implants, and
hyperemia, or bone loss would not be related to the
the occlusion, and a radiographic examination was made
shape of the intaglio surface of maxillary complete-arch
to determine the condition of the peri-implant bone
implant-supported fixed prostheses.
condition. In addition, study participants received a
prophylaxis and guidance on hygiene procedures.
MATERIAL AND METHODS
For the purposes of evaluation, the intaglio surface of
This cross-sectional analytical study had been approved the prosthesis was divided into the cantilever areas and
by the Ethics Committee of Hospital Paranaense de the regions between the implants (Fig. 1). They were
Otorrinolaringologia Ltda. (IPO) 3 350 864, and the numbered from right to left; whenever a right cantilever
Strengthening the Report of Observational Studies in was present, it was numbered area 1. The unit of analysis
Epidemiology (STROBE) initiative was followed. The was not “participant” but “area” because the same
study participants consisted of those female and male prosthesis had different intaglio surface shapes, classified
individuals aged between 36 and 71 years who had been as concave or convex, determined from the relationship it
treated with fixed complete-arch implant-supported presented with dental floss (Fig. 2). In the convex profile,
maxillary prostheses at ILAPEO College between 2005 the dental floss has full contact with the intaglio surface

Able et al THE JOURNAL OF PROSTHETIC DENTISTRY


176 Volume 128 Issue 2

Figure 3. Representative bone loss measurement of implant with mesial


bone loss and adjacent implant with no bone loss.

with a sensor (Xios Supreme; Dentsply Sirona) using the


paralleling technique with positioners (XCP DS; Dentsply
Sirona). The quality of the radiographs was considered
acceptable when all mesial and distal implant threads
could be clearly seen. Dimensional distortions were
corrected by using a software tool (Sidexis; Dentsply
Sirona) based on the actual measurement of the implant
platform. The platform was also used as a reference in
determining the presence or absence of bone loss, which
was measured in millimeters from the platform to the
level of the first visible contact between the bone and the
Figure 2. Relationship between dental floss and prosthesis intaglio
implant (Fig. 3). The measurements were performed on
surface. A, Convex surface. B, Concave surface.
the mesial and distal part of the implants by using the
same magnification and by 2 examiners (F.B.A., I.A.Y.)
of the prosthesis, presumably allowing the hygiene pro- who were calibrated by an experienced radiologist
cedures to be performed satisfactorily. Two calibrated (F.N.G.K.F.). The Spearman correlation was used to
independent evaluators (F.B.A., I.A.Y) classified the areas calculate agreement between the examiners and resulted
as concave or convex. Examiners were calibrated through in 97.5%. The bone loss for each implant was calculated
prior training to standardize evaluation. Preliminary data as the mean of the measurement of each evaluator whose
from 79 areas were analyzed by using the kappa test to measurement value was, in turn, the mean between the
verify consistency, which resulted in a concordance cor- mesial and distal part of the implant. To assess the as-
relation of 94.9%. sociation between the shape of the prosthesis intaglio
The first analysis performed was the identification of surface and bone loss, the implants were classified ac-
the presence of biofilm. Each area of the intaglio surface cording to the shape of the adjacent areas (mesial e
of the prosthesis received a score for the amount of distal) were as convex × convex, convex × concave, or
biofilm according to an adaptation of the modified concave × concave.
plaque index used by Mombelli et al24: score 0 - Study participants’ satisfaction with the rehabilitation
absence of biofilm; score 1 - biofilm detected with the at the time of the examination was assessed by using a
aid of a probe; score 2 - clinically visible biofilm; score 3 questionnaire adapted from that used by Vieira et al25
- abundant biofilm. The presence or absence of tissue with a visual analog scale (VAS). The scale ranged from
hyperemia was visually assessed by the redness or not 0 (totally dissatisfied) to 10 (completely satisfied). The
of the peri-implant tissue in each portion of the bone questionnaire consisted of the following questions: 1) Are
ridge corresponding to the areas of the intaglio of the you satisfied with your maxillary prosthesis? 2) Are you
prosthesis. These analyses were performed on all study satisfied with the esthetics of your prosthesis? 3) How do
participants by a single experienced periodontist you assess your ability to chew food? 4) How satisfied are
(F.B.A.). you with your prosthesis when you talk? 5) How satisfied
Peri-implant bone loss was assessed from periapical are you with your dentures when you smile? 6) How easy
radiographs (Heliodent Vario; Dentsply Sirona) made is it to clean your prosthesis?

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August 2022 177

Table 1. Description of biofilm accumulation per prosthesis intaglio Table 2. Analysis of relationship between prosthesis intaglio surface
surface area and analysis of relationship between prosthesis intaglio shape and tissue hyperemia
surface shape and presence of biofilm Shape
Biofilm Hyperemia Convex Concave Total
Visualization Clinically Absence 203 (52.9%) 40 (69%) 243 (55%)
Shape Absence With Probe Visible Abundant Total Presence 181 (47.1%) 18 (31%) 199 (45%)
Convex 21 (5.5%) 86 (22.4%) 222 (57.8%) 55 (14.3%) 384 (100%) Total 384 (100%) 58 (100%) 442 (100%)
Concave 2 (3.5%) 7 (12.1%) 34 (58.6%) 15 (25.9%) 58 (100%)
Friedman test. Q(1)=1.6755, P= .195.
Total 23 (5.20%) 93 (21.0%) 256 (57.9%) 70 (15.8%) 442 (100%)

Friedman test. Q(1) = 4.7571, P=.029.

Table 4. Mean (standard deviation) bone loss among different area


Table 3. Evaluation of positive relationship between presence of biofilm combinations for each implant
at prosthesis intaglio surface and hyperemia of tissue adjacent to Convex×convex 0.686 (0.050)
prosthesis Convex×concave 0.562 (0.119)
Biofilm Visualization Biofilm Clinically Biofilm Concave×concave 1.367 (0.247)
Logistic Regression With probe Visible Abundant
Coefficient 0.396 0.869 1.567
P .448 .077 .003
Table 5. Bone loss analysis between groups
Group Coefficient Standard Error P
Implant_adjacent area - - d
Convex×concave -0.125 0.133 .349
Data were statistically analyzed and described as
Concave×concave 0.675 0.194 .001
mean, standard deviation, median, minimum, and
Participant -0.002 0.002 .442
maximum. For qualitative variables, frequencies and Constant 0.748 0.095 <.001
percentages were used. Association was assessed by
using the Friedman and Linear Regression tests (a=.05
Linear regression.

for all tests). Logistic regression (±95%) was also used.


The analyses were performed by using a statistical soft-
(coefficient -0.007; odds ratio: 0.99; P=.195). Hyperemia
ware package (STATA).
was present in 199 (45%) areas and absent in 243 (55%)
areas and was not significantly different between the
RESULTS
intaglio contour shapes (P>.05) (Table 2). A positive as-
Fifty-six study participants, 42 women and 14 men, sociation was found between the presence of abundant
mean age 57 years, were enrolled into the study with 56 biofilm and hyperemia, as assessed with logistic regres-
fixed complete-arch implant-supported maxillary pros- sion (Table 3).
theses and 388 implants (Neodent). The dental status of The mean (SD) bone loss was 0.71 (0.91) mm, with a
the study participants’ mandibular arch was 22 (39.3%) maximum mean value of 4.96 mm and a minimum of
were partially edentulous restored with implant- 0 mm. The implants were classified according to the
supported partial prostheses, 20 (35.7%) had shape of the adjacent areas, resulting in 313 (80.7%)
complete-arch implant-supported fixed prostheses, 8 implants in the convex × convex group, 52 (13.4%) in the
(14.3%) were partially dentate, 5 (8.9%) were convex × concave group, and 23 (5.9%) in the concave ×
completely dentate, and 1 (1.8%) used a removable concave group. The mean (SD) bone loss of each group is
partial prosthesis. The mean ±standard deviation (SD) shown in Table 4. The linear regression analysis showed
time since placement of the maxillary prosthesis was 5.5 a significant coefficient for the variable Implant_Adjacent
(3.69) years. The classification of the intaglio surface of Area (Coef = 0.184; P=.027) but was not significant for
the prosthesis resulted in 442 areas, of which 384 the patient variable (P=.427). The group concave ×
(86.9%) were classified as convex and 58 (13.1%) as concave had a positive and significant influence on
concave. increased bone loss, but the patient variable had no
The result of the evaluation of biofilm accumulation is significant coefficient (Table 5).
shown in Table 1. A statistically significant (P<.05) as- Study participants’ satisfaction with the treatment is
sociation was detected between the shape of the intaglio shown in Figure 4. Most participants were completely
and the presence of biofilm as assessed by the Friedman satisfied with the esthetics, mastication, phonetics, and
test (Table 1). From the logistic regression analysis, the smiling (between 62.5% to 73.2%). The mean score
concave shape had a significant and slightly positive in- attributed to these factors varied between 8.46 and 8.77.
fluence (coefficient: 0.73; odds ratio: 2.07; P=.009), and Regarding the ease of cleaning the prosthesis, only 19.6%
the participant variable showed no significant influence of study participants were fully satisfied. The mean score

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178 Volume 128 Issue 2

45 41
40 36 37 37
35
Number of Participants

35
30
25
20

15 13 12
10 11
9
10 77 77 7 7
56 5 44 6
5 2 3 22 2
00000 11 000 10 10 1 0001010 00000 1 1 0 00 100 001 1
0
Satisfaction with Satisfaction with Satisfaction with Satisfaction with Satisfaction with Ease of cleaning
prosthesis esthetics mastication phonetics smiling

0 - Totally dissatisfied 1 2 3 4 5 6 7 8 9 10 - Completely satisfied

Figure 4. Summary of participants’ satisfaction with treatment and reported complaints.

attributed to this item was 6.86. Patient satisfaction with Table 6. Analysis of relationship between prosthesis intaglio surface
cleaning the prosthesis was statistically similar (P>.05) in shape and satisfaction regarding ease of cleaning prosthesis
both groups (concave and convex) according to the Ease of Cleaning
Friedman test (Table 6). Areas Mean (SD) Min. Max. N
Convex 7.11 (12.07) 2 10 384

DISCUSSION Concave 7.24 (1.52) 3 10 58

Friedman test. Q (1) =0.019, P=.89.


The results of this study determined that the intaglio
surface shape (concave or convex) of the prosthesis af-
fects biological complications; therefore, the null increasing the probability of changes in peri-implant
hypothesis was rejected. The success of a prosthetic tissues.12,13
treatment depends on comprehensive planning, design Biofilm accumulation on the protheses has been re-
of the prosthesis, and quality in the execution of the ported to play an important role in the initiation and
procedures.3,5 In addition, the maintenance of adequate progression of inflammation and infection in the denture
oral hygiene is fundamental to the long-term success of bearing area. Poor hygiene is a major factor predisposing
any dental treatment.26 Causes of the accumulation of denture surfaces to biofilm accumulation.27 Surface
biofilm in implant-supported prostheses include lack of roughness and other physical characteristics of the in-
motivation or awareness, lack of ability to perform hy- taglio surface may favor the biofilm accumulation. In the
giene procedures, and the design of the prosthesis that present study, all prostheses were made at the same
connects the implants.26 dental laboratory with heat-polymerized acrylic resin
The success of complete-arch implant-supported denture base material and denture teeth. Heat-
fixed maxillary rehabilitation and the high degree of polymerized acrylic resin has been reported to be
satisfaction of individuals treated with this type of biocompatible with oral tissues and cell cultures
prosthesis has been reported.1-4,18,20 The same was in vitro.28
observed in the present study, since study participants Information regarding the relationship between the
assigned a score between 8.46 and 8.77 for satisfaction soft tissue and the intaglio surface of the pontic areas of
with the prosthesis, esthetics, mastication, phonetics, implant-supported fixed prostheses is sparse.13 However,
and smiling. This value was close to that obtained in a concavities in the intaglio surface must be avoided to
retrospective study in which satisfaction ranged from 8.4 facilitate hygiene and avoid complications induced by
to 8.826; however, the assessment of satisfaction is biofilm.18,19 Studies that used prostheses with convex,
subjective. Regarding ease of cleaning, only 19.6% of smooth, and polished surfaces had high rates of reha-
study participants were fully satisfied, and the mean bilitation survival.18,20 The number of concave areas in
score was 6.86. This finding is consistent with other the present study was low in comparison with the
findings13,18,26 that reported that fixed prostheses can number of convex areas, because the concept of a
present contours and spaces that are difficult to clean, concavity-free intaglio surface is recommended in the

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August 2022 179

educational institution where the participants were enable proper oral hygiene procedures without compro-
rehabilitated. Nevertheless, concave areas were present, mising phonetics.18 The association found between the
because, in some situations, the shape of the residual presence of biofilm and hyperemia suggests a significant
ridge prevented a convex contour. In prostheses where a influence of the abundant accumulation of biofilm. This
convex shape is not prioritized, the number of concave result reinforces the need to avoid making prostheses with
areas may be greater. plaque-retentive areas.
The authors are unaware of a previous study that Implants associated with concave adjacent areas
compared the convex and concave intaglio surfaces of showed a higher bone loss when compared with those
implant-supported maxillary fixed prostheses. The anal- adjacent to convex areas. The presence of at least 1 convex
ysis of the presence of biofilm showed significant dif- area next to the implant was associated with a lower bone
ferences between the contours. Greater biofilm loss. In regions with concavity, hygiene procedures are
accumulation was found in concave areas: 25.9% of the challenging with increased biofilm, a risk factor for the
concave and 14.3% of the convex areas had abundant development of peri-implantitis.13,14,18,19 The mean (SD)
biofilm accumulation. In addition, the number of biofilm- bone loss measured in the present study was 0.71 (0.91)
free regions in the convex and concave areas was 21 mm, similar to the 0.3 (0.72) mm18 and 0.7 (0.6 to 0.8)
(5.5%) and 2 (3.5%), respectively. A clinical study12 that mm4 found in previous long-term studies. The greatest
evaluated the presence of biofilm on the surface of the bone loss recorded was 4.96 mm, a finding similar to that
intaglio surface of the prosthesis found that about one of a study in which the mean bone loss of implants
third was covered with biofilm. The accumulation of identified as having advanced bone loss was 5.2 mm.30
biofilm was also widespread in this study, since only With the cross-sectional design, it was not possible to
5.2% of the regions, were free of biofilm. Regarding determine whether bone loss occurred because of the
satisfaction with ease of cleaning reported by study presence of biofilm, in response to surgical trauma, or was
participants, no difference was found between the associated with the type of implant.
concave and convex shapes, suggesting that the intaglio Limitations of the present study included its cross-
surface contour is just one factor in biofilm accumula- sectional design. Therefore, it was not possible to
tion.26 Other factors include the patients ability to control all the factors related to the different surface
perform hygiene procedures and biocompatible materials characteristics, the processing of the prostheses, or the
that allow good polishing, avoiding porosities and biofilm capacity of the participants to clean their prosthesis.
accumulation. The importance of informing patients of Additionally, the number of concave areas was not
the hygiene procedures and follow-up appointments to controlled or randomized. Additional studies examining
reinforce these guidelines, of carrying out professional the contours of the intaglio surface of complete-arch
hygiene, and of polishing the prosthesis is stressed. implant-supported maxillary fixed prostheses are
Follow-up appointments are also important for reducing needed to provide detailed evidence on this topic.
the risk or severity of mucositis and peri-implantitis, bone
loss, and bleeding and, therefore, for reducing the CONCLUSIONS
complication rates.2,6,19,21,22
Based on the findings of this cross-sectional analytical
Oral mucosal lesions associated with the use of a
study, the following conclusions were drawn:
prosthesis may be related to the presence of biofilm, to
reaction to the prosthetic material, or to mechanical 1. The shape of the intaglio surface of fixed maxillary
trauma.29 In the present study, hyperemia was the oral implant-supported prostheses influenced the
condition evaluated. Since no reaction to the prosthesis occurrence of biological complications.
material was identified for any study participant, the most 2. Concave areas presented greater biofilm accumula-
likely cause of the hyperemia was a reaction to biofilm or to tion and bone loss.
excessive contact of the prosthesis with the mucosa. This 3. Study participants showed a high level of satisfac-
hypothesis explains the absence of significant differences tion with the prosthesis for esthetics, mastication,
between groups (concave and convex), since concave areas smiling, and speaking. However, few participants
were more associated with biofilm accumulation during reported being completely satisfied with the ease of
clinical evaluations. However, in some convex regions, the cleaning.
intaglio surface of the prosthesis was in strong contact with
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tologic observation in humans. J Prosthet Dent 2000;88:375-80. The authors thank the Faculdade ILAPEO for making possible the development of
17. Kim TH, Cascione D, Knezevic A. Simulated tissue using a unique pontic this study and the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
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19. Penarrocha-Diago M, Penarrocha-Diago M, Zaragozí-Alonso R, Soto- Francine Baldin Able: Conceptualization, Methodology, Investigation, Valida-
Penaloza D. On Behalf Of The Ticare Consensus M. Consensus statements tion, Writing - original draft, Writing - review & editing. Nara Hellen
and clinical recommendations on treatment indications, surgical procedures, Campanha: Methodology, Validation, Writing - review & editing. Ibrahim
prosthetic protocols and complications following All-On-4 standard treat- Abazar Younes: Conceptualization, Methodology, Investigation, Validation,
ment. 9th Mozo-Grau Ticare Conference in Quintanilla, Spain. J Clin Exp Writing - review & editing. Ivete Aparecida de Mattias Sartori: Methodology,
Dent 2017;9:e712-5. Validation, Writing - review & editing.
20. Tischler M, Patch C, Bidra AS. Rehabilitation of edentulous jaws with zirconia
complete-arch fixed implant-supported prostheses: An up to 4-year retro- Copyright © 2021 by the Editorial Council for The Journal of Prosthetic Dentistry.
spective clinical study. J Prosthet Dent 2018;120:204-9. https://doi.org/10.1016/j.prosdent.2020.12.028

THE JOURNAL OF PROSTHETIC DENTISTRY Able et al

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