Ersteller: Directive /

kas safe operating procedure for hazardous materials

according GefStoffV

AREA OF APPLICATION

Labor A2.04 (INM)

NAME OF HAZARDOUS SUBSTANCE

Y-27632 (hydrochloride) (129830-38-2)

Application
ROCK Inhibitor drugs in Cell culture application
HAZARDS OVERVIEW FOR HUMANS AND ENVIRONMENT
bsp Classification of the substance or mixture

GHS07
Acute Tox. 4 H302 Harmful if swallowed.
Acute Tox. 4 H312 Harmful in contact with skin.
Acute Tox. 4 H332 Harmful if inhaled.

Signalwort:
Gefahr!

SAFETY INSTRUCTIONS AND RULES OF CONDUCT

Signal word Warning

Hazard statements
H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled.
Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapors/spray
P264 Wash thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves / protective clothing.
P301+P312 If swallowed: Call a poison center/doctor if you feel unwell.
P302+P352 If on skin: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P321 Specific treatment (see on this label).
P330 Rinse mouth.
P362+P364 Take off contaminated clothing and wash it before reuse.
P501 Dispose of contents/container in accordance with local/regional/national/international
regulations.
Classification system:
NFPA ratings (scale 0 - 4)
Health = 3
Fire = 0
Reactivity = 0
HMIS-ratings (scale 0 - 4)
REACTIVITY
Health = 2
Fire = 0
Reactivity = 0
Other hazards
Results of PBT and vPvB assessment
 PBT: Not applicable.
vPvB: Not applicable.
Handling:
Precautions for safe handling
Thorough dedusting.
Ensure good ventilation/exhaustion at the workplace
Information about protection against explosions and fires: No special measures required.
Conditions for safe storage, including any incompatibilities
Storage: Store in accordance with information listed on the product insert.
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: Keep receptacle tightly sealed.
Specific end use(s) No further relevant information available.

ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures Not required.
Environmental precautions: Do not allow to enter sewers/ surface or ground water.
Methods and material for containment and cleaning up: Ensure adequate ventilation.
Protective Action Criteria for Chemicals
PAC-1: Substance is not listed.
PAC-2: Substance is not listed.
PAC-3: Substance is not listed.
FIRST AID
Description of first aid measures
General information:
Symptoms of poisoning may even occur after several hours; therefore medical observation for
at least 48 hours after the accident.
After inhalation:
Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if
Notruf: symptoms persist.
0 112 In case of unconsciousness place patient stably in side position for transportation.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: Immediately call a doctor.
Information for doctor:
Most important symptoms and effects, both acute and delayed
May cause anemia, cough, CNS depression, drowsiness, headache, heart damage, lassitude
(weakness, exhaustion), liver damage, narcosis, reproductive effects, teratogenic effects.
No further relevant information available.
Indication of any immediate medical attention and special treatment needed.
No further relevant information available.
LEGAL WASTE DISPOSAL
•
Date: Signature (lab manager): (kas) Next examination: