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Forteo Injection
Teriparatide
20mcg/80mcl
LILLY FRANCE SA

Pack size 3ml Pen (28 Doses)


Dispensing mode POM
Source FRANCE
Agent PHARMATRADE
Retail Price 2389.00 AED

Other Brands

Indications

Forteo Injection is used for:


Digoxin (Use with caution. Teriparatide
transiently increases serum calcium, which
may lead to digitalis toxicity)

Adult Dose

By subcutaneous injection, 20 micrograms


of teriparatide once daily.
Maximum total duration of treatment with
teriparatide is 2 years.
After teriparatide is discontinued, patients
may continue other osteoporosis therapies.

Hepatic impairment: No data available

NOTE:
In addition to teriparatide, patients should
receive calcium and vitamin D supplements
if dietary intake is inadequate.
Teriparatide may cause small and transient
elevations of serum calcium
concentrations. When blood samples are
required, obtain the sample at least 16
hours after the most recent teriparatide
dose

Child Dose

Do not use in pediatric patients or young


adults with open epiphyses

Renal Dose

Moderate renal impairment: Use with


caution.
Severe renal impairment: Do not use

Administration

For Subcutaneous administration.


Administer subcutaneously in the thigh or
abdomen.
Initially administer in an environment in
which the patient can assume a supine or
sitting position if orthostatic hypotension
occurs.
Before administering teriparatide, visually
inspect the product for particulate matter
and discoloration

Contra Indications

Hypersensitivity to teriparatide or any of the


excipients.
Pre-existing hypercalcemia.
Severe renal impairment.
Metabolic bone diseases other than
primary osteoporosis (including
hyperparathyroidism and Paget's disease
of the bone) or glucocorticoid-induced
osteoporosis.
Unexplained elevations of alkaline
phosphatase.
Prior external beam or implant radiation
therapy to the skeleton.
Patients with skeletal malignancies or bone
metastases.
Pregnancy; Breastfeeding

Precautions

Active or recent urolithiasis.


Concurrent use with digitalis.
Pre-existing hypercalciuria.
Active or recent urolithiasis.
Avoid use in patients who are
breastfeeding.
Do not use in pediatric patients or young
adults with open epiphyses

Pregnancy-Lactation

Pregnancy:
Reproductive toxicity observed in animal
studies. Consider discontinuing when
pregnancy occurs. Use only if the potential
benefit outweighs the potential risk to the
fetus.

Lactation:
Potential for tumorigenicity. Breastfeeding
is not recommended.

References:
1. Forteo [Internet]. Eli Lilly; [cited 2021
March 12]. Available from:
https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?
setid=aae667c5-381f-4f92-93df-
2ed6158d07b0&type=display
2. Osteotide [Internet]. Virchow; [cited 2021
March 12]. Available from:
http://osteotide.org/forHealthcareProviders.html

Interactions

Digoxin (Use with caution. Teriparatide


transiently increases serum calcium, which
may lead to digitalis toxicity)

Adverse Effects

Side effects of Teriparatide :


Most common adverse events are nausea,
pain in limb, headache and dizziness.
Other adverse effects include myalgia,
arthralgia, hypercalcaemia, hyperuricemia
(especially in patients with moderate renal
impairment and those receiving teriparatide
40 mcg/day), and mild injection site
reactions such as pain, swelling,
erythema, localized bruising, pruritus, and
minor bleeding.
Transient orthostatic hypotension observed
in clinical studies – usually occurred within
4 hours of an initial dose and
spontaneously resolved within a few
minutes to a few hours

Mechanism of Action

Note

Forteo 20mcg/80mcl Injection


manufactured by LILLY FRANCE SA. Its
generic name is Teriparatide. Forteo is
availble in United Arab Emirates.
Farmaco UAE drug index information on
Forteo Injection is not intended for
diagnosis, medical advice or treatment;
neither intended to be a substitute for the
exercise of professional judgment.

Some other brands of Teriparatide :

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