1.

Test for carcinogenicity

a. Kveim’s test
b. Ame’s test
c. Schilling’s test
d. Schick test
2. Calcitonin is a marker of:
a. prostate cancer
b. medullary carcinoma of the thyroid
c. pheochromocytoma
d. pancreatic cancer
3. The B27 HLA allele is associated with the following condition:
a. Ankylosing spondylitis
b. Psoriasis
c. Inflammatory bowel disease
d. All of the above
4. P53 is activated by
a. phosphorylation
b. dephosphorylation
c. methylation
d. carboxylation
5. What is the most common site of origin of thrombotic pulmonary emboli?
a. Deep leg veins
b. Lumen of left ventricle
c. Lumen of right ventricle
d. Superficial leg veins
6. A biopsy of an enlarged salivary gland from an individual with Sjögren’s syndrome is most likely
to histologically reveal an extensive infiltrate of
a. Basophils
b. Eosinophils
c. Lymphocytes
d. Neutrophils
7. A 4-year-old male with mental retardation, self-mutilation, and hyperuricemia is likely to have a
deficiency of an enzyme involved in the
a. Conversion of homogentisic acid to methylacetoacetate
b. Breakdown of branched-chain amino acids
c. Recycling of guanine and hypoxanthine
d. Synthesis of UMP and CTP
8. Procoagulant factors produced by endothelial cells include
a. Thrombomodulin
b. Prostacyclin
c. von Willebrand factor
d. Fibrinogen
9. An 8-year-old boy is found to have progressive corneal vascularization, deafness, notched incisors,
and a flattened nose. The most likely cause of these changes is congenital infection by
a. Toxoplasma
b. Rubella
c. Cytomegalovirus
d. T. pallidum
10. The decrease in serum iron, decrease TIBC is seen in -
a. Iron deficiency anemia
b. Thalassemia
c. Anemia of chronic disease
d. Sideroblastic anemia
11. Platelets are usually stored at what temperature?
a. 1-6ºc
 b. 22ºc
c. -25ºc
d. 40ºc
12. Leptocyte in blood smears seen in?
a. Sickle cell anemia
b. Thalassemia
c. Postsplenectomy
d. Uremia
13. Ring sideroblast in myelodysplastic syndrome is associated with which gene mutation?
a. ASXL1
b. EZH2
c. TET2
d. SF2B1
14. Sezary cells show which type of nucleus-
a. Pleomorphic
b. Round
c. Eosinophilia
d. Cerebriform
15. Autoimmune hemolytic anemia is seen in-
a. ALL
b. AML
c. CLL
d. CML
16. What is the optimal use of the ratio of RBC: FFP: PLATELETS in massive transfusion
blood products in severely injured trauma patients:
a. 1:1:1
b. 1:2:3
c. 1:3:5
d. 2:1:4
17. About transfusion-related lung injury what is not true:
a. Mortality <10% of cases
b. Subsides within 2-3 weeks
c. Supportive care is the mainstay of treatment
d. steroids use is not well established
18. Best blood product to be given in a patient of multiple clotting factor deficiency with
active bleeding is:
a. Fresh frozen plasma
b. Whole blood
c. Packed RBCs
d. Cryoprecipitate
19.The chromosome of the Rh gene is located in which chromosome:
a. Chr 1
b. Chr 3
c. Chr 9
d. Chr 19
20. Scar contraction is caused by
a. Fibroblasts
b. Myofibroblasts
c. Epithelial cells
d. None