Syndrome of

Inappropriate
Antidiuretic Hormone

NCMB316 LEC
Syndrome of inappropriate antidiuretic
hormone
(SIADH)
 Syndrome of inappropriate
antidiuretic hormone
SIADH:
a condition were the body produces too much of hormone
ADH also called Vasopressin leading to decreasing the
blood osmolality which refers to the concentration of
dissolved particles like Sodium & other Electrolytes

Normal Blood Osmolality is

285 - 295 mOsm/Kg
 Causes of siadh
Paraneoplastic Syndrome
Tumor Outside brain secretes ADH
small cell lung carcinoma
Pneumonia Head Trauma
Damages Pituitary
stored ADH released

Chronic Obctructive Pukmonary Disease (COPD)

Surgeries of CNS
 Causes of siadh
Antihypertensive Medication
Seizure Medication
-Thiazide Diuretics
-Carbamazepine

Chemothrapeutics
Antidepressants
-Cyclophosphamide
-SSRIs

Analgesic Medication
-Antidiabetic Medications
-NSAIDs
 Risk Factors
Advance Age - Having Chronic Conditions

Epilepsy Heart Failure Diabetes Mellitus

 Nursing Diagnosis
Nursing Diagnosis: Excess Fluid Volume
Related to:
Disease process
Excessive fluid intake
Compromised regulatory mechanism
Endocrine regulatory dysfunction
Renal dysfunction
As evidenced by:
Intake exceeds output
Concentrated urine
Oliguria
Low sodium levels
Decreased hematocrit
Expected outcomes:
The patient will maintain electrolytes within acceptable ranges
The patient will maintain balanced intake and output
 NUrsing management

You will restrict fluids and replace sodium as ordered by the provider.
Monitor for fluid volume excess. If the patient has too much fluid volume overload, that
can lead to pulmonary edema which is life threatening, so it’s important to monitor for
that.