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Water

Role of water in the human body


water balance & some diseases
associated with its disturbance

Prof. Kalana Maduwage


MBBS, MPhil, Ph.D, FRSPH (UK)
Department of Biochemistry
Faculty of Medicine
University of Peradeniya

29 October 2022
Water
• Is the solvent of life

• dipolar molecule

• form hydrogen bonds with other organic polar molecules &


inorganic salts
Water and Hydrogen Bond Formation

• single H2O molecule forms 4 hydrogen bonds

• hydrogen bonds weaker then covalent bonds (1/20)

• H2O lattice frame is dynamic (continuously breaking and reforming )

• polar solutes can easily make H bonds with H2O


Oedema

Accumulation of excess water in


the interstitial space
Fluids in sports
Fluids in sports

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