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Drug name Classification and Indications and Side effects and Special Precautions Nursing Responsibilities

Mechanism of Action Contraindications Adverse Effects

Generic Name: Classification: Indication: Body as a


Carvedilol Whole: Increased You may experience Monitor for therapeutic
Autonomic nervous Management of sweating, fatigue, chest dizziness or faintness, as a effectiveness which is
Brand name: system agent, alpha – and essential pain, pain, arthralgia. risk of orthostatic indicated by lessening of S&S
Coreg beta- adrenergic hypertension, CHF, in CV: Bradycardia, hypotension. of CHF and improved BP
Kredex antagonist and conjunction with hypotension, syncope, control.
Antihypertensive other heart failure hypertension, AV block, Do not engage in hazardous
Dosage: medications, left angina. activities while experiencing Monitor for worsening of
Mechanism of Action: ventricular GI: Diarrhea, nausea, dizziness. symptoms in patients with
6.25 mg/tab dysfunction post MI. abdominal pain, vomiting. PVD.
Respiratory: Sinusitis, If you have diabetes, the
Route: Adrenergic receptor Contraindications: bronchitis. drug may increase effects of Monitor digoxin levels with
Oral blocking agent that Hematologic: Thrombocyt hypoglycemic drugs and concurrent use; plasma
combines selective alpha Patients with class IV openia, mask S&S of hypoglycemia. digoxin concentration may
Frequency and activity and nonselective decompensated Metabolic: Hyperglycemia, increase.
Timing beta-adrenergic blocking cardiac failure, weight increase, gout.
OD actions. Both activities bronchial asthma, or CNS: Dizziness, headache,
contribute to blood related paresthesias Monitor liver function tests
pressure reduction. bronchospastic periodically; at first sign of
Peripheral vasodilatation conditions (e.g., hepatic toxicity (see Appendix
and, therefore, decreased chronic bronchitis F) stop drug and notify
peripheral resistance and emphysema), physician.
results from alpha1- second- and third-
blocking activity of Coreg. degree AV block,
It is 3–5 times more cardiogenic shock or
potent than labetalol in severe bradycardia.
lowering blood pressure
Drug name Classification and Indications and Side effects and Special Precautions Nursing Responsibilities
Mechanism of Action Contraindications Adverse Effects

Generic Name: Classification: Indication:


Piperacillin + CNS: Headache, Report rash, itching, or other Obtain history of
Tazobactam Anti-infective, beta- Treatment of moderate to insomnia, fever. signs of hypersensitivity hypersensitivity to penicillins,
lactam antibiotic, and severe appendicitis, immediately. cephalosporins, or other
Brand name: antipseudomonal uncomplicated and GI: Diarrhea, drugs prior to administration.
Zosyn penicillin complicated skin and skin constipation, Report loose stools or
structure infections, nausea, vomiting, diarrhea as these may C&S prior to first dose of the
Dosage: Mechanism of Action: endometritis, pelvic dyspepsia, pseudom indicate drug; start drug pending
inflammatory disease, or embranous colitis. pseudomembranous colitis. results. Monitor hematologic
2.25 mg nosocomial or community- status with prolonged therapy
Antibacterial combination acquired pneumonia caused Skin: Rash, pruritus, If you have diabetes, the (Hct and Hgb, CBC with
Route: product consisting of the by piperacillin-resistant, hypersensitivity drug may increase effects of differential and platelet count
Intravenous semisynthetic piperacillin piperacillin/tazobactam- reactions. hypoglycemic drugs and
and the beta-lactamase susceptible, beta-lactamase- mask S&S of hypoglycemia.
Frequency and inhibitor tazobactam. producing bacteria.
Timing Tazobactam component Monitor patient carefully
Q8H ANST does not decrease the Contraindications: during the first 30 min after
activity of the piperacillin initiation of the infusion for
component against Hypersensitivity to signs of hypersensitivity
susceptible organisms. piperacillin, tazobactam,
penicillins, cephalosporins,
or beta-lactamase inhibitors
such as clavulanic acid and
sulbactam.
Drug name Classification and Indications and Side effects and Special Precautions Nursing Responsibilities
Mechanism of Action Contraindications Adverse Effects

Generic Name: Classification: Indication:


Acetylcysteine CNS: Dizziness, Report difficulty Monitor for S&S of aspiration of
Skim and mucous Adjuvant therapy in patients drowsiness. with clearing the excess secretions, and for
Brand name: membrane agent, with abnormal, viscid, or airway or any other bronchospasm (unpredictable);
Mucomyst mucolytic, and antidote inspissated mucous GI: Nausea, vomitin respiratory distress. withhold drug and notify physician
Exflem secretions in acute and g, stomatitis, immediately if either occurs.
Mechanism of Action: chronic bronchopulmonary hepatotoxicity Report nausea, as an
Dosage: diseases, and in pulmonary (urticaria). antiemetic may be Monitor ABGs, pulmonary
complications of cystic indicated. functions and pulse oximetry as
600 mg dissolve 1 Acetylcysteine probably fibrosis and surgery, Respiratory: Bronch indicated.
sachet in 50 ml of acts by disrupting tracheostomy, and atelectasis. ospasm, rhinorrhea, Unpleasant odor of
water disulfide linkages of Also used in diagnostic burning sensation in inhaled drug Nausea and vomiting may occur,
mucoproteins in bronchial studies and as an upper respiratory becomes less particularly when face mask is
Route: purulent and antidote for acute passages, epistaxis. noticeable with used, due to unpleasant odor of
Oral nonpurulent secretions. acetaminophen poisoning. continued use. drug and excess volume of
liquefied bronchial secretions.
Frequency and Contraindications:
Timing
OD Hypersensitivity to
acetylcysteine; patients at risk
of gastric hemorrhage.
Drug name Classification and Indications and Side effects and Adverse Special Precautions Nursing
Mechanism of Action Contraindications Effects Responsibilities
Classification: Indication: Avoid licorice; large amounts Monitor for and report
Generic GI: Nausea, can cause both hypokalemia signs of GI
Name: Electrolytic and water To prevent and treat potassium vomiting, diarrhea, abdominal and sodium retention ulceration Monitor
Furosemide balance agent and deficit secondary to diuretic or distension. ABGs, pulmonary
+ Potassium replacement solution corticosteroid therapy. Also Do not use any salt substitute functions and pulse
indicated when potassium is Body as a Whole: Pain, unless it is specifically ordered oximetry as indicated.
Brand name: Mechanism of Action: depleted by severe vomiting, mental confusion, irritability, by the physician. These contain
Diumide - K diarrhea; intestinal drainage, listlessness, paresthesias of a substantial amount of Monitor I&O ratio and
Principal intracellular fistulas, or malabsorption; extremities, muscle weakness potassium and electrolytes pattern in patients
Dosage: cation; essential for prolonged diuresis, diabetic and heaviness of limbs, other than sodium. receiving the parenteral
maintenance of acidosis. Effective in the difficulty in drug. If oliguria occurs,
intracellular isotonicity, treatment of hypokalemic swallowing, flaccid paralysis. Do not self-prescribe laxatives. stop infusion promptly
Route: transmission of nerve alkalosis (chloride, not the Chronic laxative use has been and notify physician.
Oral impulses, contraction gluconate). Urogenital: Oliguria, anuria. associated with diarrhea–
of cardiac, skeletal, and induced potassium loss. Monitor patients
Frequency smooth muscles, Contraindications: Hematologic: Hyperkalemia. receiving parenteral
and Timing maintenance of normal Report continuing signs of potassium closely with
OD kidney function, and Severe renal impairment; severe Respiratory: Respiratory potassium deficit to physician: cardiac monitor.
for enzyme activity. hemolytic reactions; untreated distress. Weakness, fatigue, polyuria, Irregular heartbeat is
Plays a prominent role Addison's disease; crush polydipsia. usually the earliest
in both formation and syndrome; early postoperative CV: Hypotension, clinical indication of
correction of oliguria (except during GI bradycardia; cardiac Do not open foil-wrapped hyperkalemia.
imbalances in acid– drainage); adynamic ileus; acute depression, arrhythmias, or powders and tablets before
base metabolism. dehydration; heat cramps, arrest; altered sensitivity to use. Be alert for potassium
hyperkalemia, patients receiving digitalis glycosides. ECG intoxication may result
potassium-sparing diuretics, changes in hyperkalemia: from any therapeutic
digitalis intoxication with AV dosage, and the patient
conduction disturbance. may be asymptomatic.
Drug name Classification and Indications and Side effects and Adverse Special Precautions Nursing
Mechanism of Action Contraindications Effects Responsibilities

Generic Classification: Indication:


Name: Body as a Report chills, wheezing, Determine previous
Ampicillin Anti- Infective, Treatment of infections due to Whole: Hypersensitivity (rash, pruritus (itching), respiratory hypersensitivity
sodium and Antibiotic and susceptible organisms in skin itching, anaphylactoid distress, or palpitations to reactions to penicillins,
Sulbactam Aminopenicillin and skin structures, reaction), fatigue, malaise, physician immediately. cephalosporins, and
Sodium intraabdominal infections, and headache, chills, edema. other allergens prior to
Mechanism of Action: gynecologic infections. therapy.
Brand name: GI: Diarrhea,
Silgram Contraindications: nausea, vomiting, abdominal Report promptly
Antibiotic agent with distention, candidiasis. unexplained bleeding
Dosage: activity resulting from Hypersensitivity to penicillins; (e.g., epistaxis, purpura,
beta-lactamase mononucleosis. Hematologic: Neutropenia, ecchymoses).
750 mg/tab inhibition. Sulbactam thrombocytopenia.
inhibits beta- Observe for and report
Route: lactamases most Urogenital: Dysuria. CNS: Sei symptoms of
Oral frequently responsible zures. superinfections.
for transferred drug Withhold drug and
Frequency resistance. Because of Other: Local pain at injection notify physician.
and Timing this action, a wide site; thrombophlebitis.
BID for 7 days range of beta- Monitor I&O ratio and
lactamases found in pattern. Report dysuria,
organisms resistant to urine retention, and
penicillins and hematuria.
cephalosporins have
their growth inhibited.
Drug name Classification and Indications and Side effects and Special Precautions Nursing Responsibilities
Mechanism of Action Contraindications Adverse Effects
Ingest some form of sugar
Generic Name: Classification: Indication: (e.g., orange juice, dissolved
Insulin Aspart Body as a table sugar, honey) if Monitor for S&S of
Hormone and synthetic Treatment of diabetes Whole: Allergic symptoms of hypoglycemia hypoglycemia. Initial
Brand name: substitute, Antidiabetic mellitus. reactions. develop, and seek medical hypoglycemic response
Ryzoden agent and Insulin assistance. begins within 15 min and
Contraindications: Endocrine: Hypoglyce peaks 45–90 min after
Dosage: Mechanism of Action: mia, hypokalemia. Notify the physician of any injection.
Systemic allergic of the following: Fever,
15 units reactions; history of Skin: Injection site infection, trauma, diarrhea, Periodically monitor
A recombinant insulin allergic reactions to reaction, nausea or vomiting. Dosage fasting blood glucose and
Route: analog that is more rapidly insulin; hypoglycemia lipodystrophy, pruritus, adjustment may be needed. HbA1C.
Subcutaneous absorbed than human rash.
insulin, with a more rapid Do not take any other
Frequency and onset and shorter duration medication unless approved
Timing than regular human insulin. by the physician. Withhold drug and notify
OD physician if patient is
Do not inject into areas with hypokalemic.
redness, swelling, itching, or
dimpling.
Drug name Classification and Indications and Side effects and Special Precautions Nursing Responsibilities
Mechanism of Action Contraindications Adverse Effects
Control BP adequately prior
Generic Name: Epoetin Alfa Classification: Indication: to initiation of therapy and
CNS: Seizures, he Important to comply closely monitor and control
Brand name: Blood formers, Elevates the hematocrit of adache. with antihypertensive during therapy. Hypertension
Eposino Coagulators and patients with anemia medication and is an adverse effect that must
Epogen Anticoagulant, secondary to chronic kidney CV: Hypertension. dietary restrictions. be controlled.
Hematopoietic growth failure (CRF); patients may or
Dosage: factor. may not be on dialysis; Do not drive or Be aware that BP may rise
other anemias related to GI: Nausea, engage in other during early therapy as the
4000 iu Mechanism of Action: malignancies and AIDS. diarrhea. potentially hazardous Hct increases. Notify
Autologous blood donations activity during the physician of a rapid rise in Hct
Route: for anticipated transfusions. Hematologic: Iro first 90 d of therapy (>4 points in 2 wk). Dosage
Subcutaneous Glycoprotein that Reduces need for blood in n because of possible will need to be reduced
stimulates RBC anemic surgical patients. deficiency, throm seizure activity. because of risk of serious
Frequency and Timing production. Hypoxia and bocytosis, clottin hypertension.
anemia generally Contraindications: g of AV fistula. Understand that
Twice per week X 4 more increase the production headache is a Monitor for hypertensive
doses of erythropoietin. Uncontrolled hypertension Other: Sweating, common adverse encephalopathy in patients
and known hypersensitivity bone pain, effect. Report if with CRF during period of
to mammalian cell–derived arthralgias. severe or persistent, increasing Hct.
products and albumin may indicate
(human). developing Monitor closely for
hypertension. thrombotic events (e.g., MI,
CVA, TIA), especially for
Keep all follow-up patients with CRF.
appointments.
Drug name Classification and Indications and Side effects and Special Precautions Nursing Responsibilities
Mechanism of Action Contraindications Adverse Effects

Generic Name: Classification: Indication:


Sevelamer Hydrochloride Body as a Do not use capsules Obtain frequent serum
Electrolyte and water Reduction of serum Whole: Headach after printed phosphate levels.
Brand name: balance agent and phosphorus in patients with e, infection, pain. expiration date.
Renalog Phosphate Binder end-stage kidney disease.
CV: Hypertension, Take daily
Dosage: Mechanism of Action: Contraindications: hypotension, multivitamin
thrombosis. supplement approved
2 tabs Hypophosphatemia; by physician.
Polymer that binds hypersensitivity to GI: Diarrhea,
Route: intestinal phosphate; sevelamer HCl; bowel dyspepsia,
Oral interacts with phosphate obstruction; pregnancy vomiting, nausea,
by way of ion-exchange (category C), lactation. constipation,
Frequency and Timing and hydrogen binding. Safety and efficacy in flatulence.
Advantageously, does children <18 y are not
TID not contain aluminum established. Respiratory: Incr
or calcium acetate in eased cough.
treating
hyperphosphatemia in
end stage kidney failure.
Drug name Classification and Indications and Side effects and Adverse Effects Special Nursing Responsibilities
Mechanism of Action Contraindications Precautions

Generic Name: Classification: Indication: Body as a Whole: Flu-like


Clopidogrel syndrome, fatigue, pain, Report promptly Carefully monitor for and
Blood formers, Secondary prevention of arthralgia, back pain. any unusual immediately report S&S of GI
Brand name: coagulators, MI, stroke, and vascular bleeding (e.g., bleeding, especially when
Plavix anticoagulant and death in patients with CV: Chest pain, edema, black, tarry coadministered with NSAIDs,
antiplatelet agent. recent MI, stroke, hypertension, thrombocytic stools). aspirin, heparin, or warfarin.
Dosage: unstable angina or purpura.
Mechanism of Action: established peripheral Avoid chronic Lab tests: Periodic platelet
75 mg arterial disease. GI: Abdominal pain, dyspepsia, aspirin count and lipid profile.
diarrhea, nausea, or NSAID use
Route: Inhibits platelet Contraindications: hypercholesterolemia. unless approved Evaluate patients with
Oral aggregation by by physician. unexplained fever or infection
selectively preventing Hypersensitivity to Hematologic: Thrombotic for myelotoxicity.
Frequency and the binding of clopidogrel; intracranial thrombocytopenic purpura,
Timing adenosine diphosphate hemorrhage, peptic ulcer, epistaxis.
to its platelet receptor. or any other active
OD It is an analog of pathologic bleeding; CNS: Headache, dizziness,
ticlopidine. The drug's pregnancy (category B). depression.
effect on the Discontinue clopidogrel 7
adenosine diphosphate d before surgery and Respiratory: URI, dyspnea,
receptor of a platelet is during lactation. Safety rhinitis, bronchitis, cough.
irreversible. and efficacy not
established in children. Skin: Rash, pruritus.
Drug name Classification and Indications and Side effects and Adverse Effects Special Nursing Responsibilities
Mechanism of Action Contraindications Precautions

Generic Name: Classification: Indication:


Amlodipine CV: Palpitations, flushing Report significant Monitor BP for therapeutic
Cardiovascular Agent, Treatment of mild to tachycardia, peripheral or facial swelling of face effectiveness. BP reduction is
Brand name: Calcium channel moderate hypertension edema, bradycardia, chest pain, or extremities. greatest after peak levels of
Norvasc blocker, and and angina. syncope, postural hypotension. amlodipine are achieved 6–9
antihypertensive agent Take care to have h following oral doses.
Dosage: Contraindications: CNS: Light-headedness, support when
Mechanism of Action: fatigue, headache. standing & Monitor for S&S of dose-
40 mg 1 tab Amlodipine is a Hypersensitivity to walking due to related peripheral or facial
calcium channel amlodipine GI: Abdominal pain, nausea, possible dose- edema that may not be
Route: blocking agent that anorexia, constipation, dyspepsia, related light- accompanied by weight gain;
Oral selectively blocks dysphagia, diarrhea, flatulence, headedness/dizzi rarely, severe edema may
calcium ion reflux vomiting. ness. cause discontinuation of
Frequency and across cell membranes drug.
Timing of cardiac and vascular Urogenital: Sexual dysfunction, Report shortness
smooth muscle frequency, nocturia. of breath, Monitor BP with postural
OD without changing palpitations, changes. Report postural
serum calcium Respiratory: Dyspnea. irregular hypotension. Monitor more
concentrations. It heartbeat, frequently when additional
predominantly acts on Skin: Flushing, rash. nausea, or antihypertensives or diuretics
the peripheral constipation to are added.
circulation, decreasing Other: Arthralgia, cramps, physician.
peripheral vascular myalgia. Monitor heart rate; dose-
resistance, and related palpitations (more
increases cardiac common in women) may
output. occur.
Nursing Care Plan

Case 1: Ischemic Heart Disease

Defining Nursing Outcome Nursing Rationale Evaluation

Characteristics Diagnosis Identification Intervention

Long Term Goal Independent: Goals met as


evidenced by
Subjective Acute Pain related to Instruct patient to Unbearable pain may
Data: decrease myocardial notify nurse immediately cause vasovagal Long Term Goal
After 56 hours of
blood flow as when chest pain occurs. response, decreasing BP
“Ga pin ot nursing After 56 hours of
evidenced by reports interventions the and heart rate.
akon dughan nursing
of pain varying in client will be able to interventions the
as verbalized Provides information
frequency, duration, demonstrate relief Assess and document client will be able to
by the parint. about disease
and intensity. of pain as evidenced patient response to demonstrate relief
by stable vital signs, progression. Aids in
medication. of pain as
Rationale: absence of muscle evaluating effectiveness evidenced by stable
Objective tension and of interventions vital signs, absence
is a condition in restlessness
Data: of muscle tension
which plaque builds Identify precipitating Helps differentiate this and restlessness
Weight: 90kg up inside the event, if any: frequency, chest pain, and aids in
coronary arteries. evaluating possible
Pain Scale: 9 Plaque is made up of duration, intensity, and progression to unstable Short Term Goal
out of 10 fat, cholesterol, location of pain. angina.
Short Term Goal
calcium, and other
Conscious, Evaluate reports of pain Cardiac pain may
substance found in After 24 hours of After 24 hours of
coherent and in jaw, neck, shoulder, radiate. Pain is often
the blood. Plaque nursing intervention referred to more nursing intervention
oriented; has the client will be arm, or hand (typically the client will be
narrows the arteries superficial sites served
crackles on able to report on left side). able to report
and reduces blood by the same spinal
both lung anginal episodes anginal episodes
flow to your heart cord nerve level.
fields on decreased in decreased in
muscle. It also makes
auscultation, frequency, duration, frequency, duration,
it more likely that Place patient at
and severity. Reduces myocardial and severity.
cardiac rate complete rest during
blood clots will form oxygen demand to
irregular, with anginal episodes.
in your arteries. This minimize risk of
cool, moist,
can cause angina or tissue injury.
pale skin.
a heart attack
without quick Elevate head of bed if Facilitates gas exchange
Vital signs:
treatment. patient is short of to decrease hypoxia
Temp.: 37.8 C breath. and resultant shortness
of breath.
BP: 90/60
mmHg Note: Blood pressure may
Monitor vital signs every initially rise because of
PR: 56 bpm.
5 min during initial sympathetic
RR: 30 cpm Nursing Diagnosis anginal attack. stimulation, then fall if
should be base cardiac output is
from (NANDA- Maintain quiet, compromised.
comfortable
Approved Nursing environment. Restrict Mental/emotional stress
Diagnosis) visitors as necessary. increases myocardial
workload.

Dependent:

Prescribe medication as
ordered:

• Alteplase 100
mgs in 200 cc
PNSS via IV
infusion over 3
hours:
60 mgs on the
first hour, 6- 10
mgs of which is
given as bolus
over first 1-2
minutes. Then 20
mgs/ hour
infused for 2
hours.
• Atenolol 50 mgs
1 tablet daily
• Isosorbide
dinitrate (
Isordil) tablet 5
mgs p.o. every Used to treat the
12 hours before patient’s condition
meal
• Lactulose Syrup
30 ml p.o. at
bedtime
• Enoxaparin
Sodium
(Lovenox) 30 mgs
Subcutaneously
daily
• Lorazepam 2 mgs
1 tablet at
bedtime
• Clopidogrel 75
mgs 1 tablet daily
after lunch
• Morphine Sulfate
10 mgs tablet
every 4 hours
PRN for chest pai
• Cefazolin 500
mgs every 8
hours ANST
Nursing Care Plan

Case 2: End Stage Renal Failure

Defining Nursing Outcome Nursing Rationale Evaluation

Characteristics Diagnosis Identification Intervention

Long Term Goal Independent: Goals met as


evidenced by
Subjective Impaired Urinary Establish rapport. To get the
Data: Elimination related to cooperation of the Long Term Goal
failing glomerular After 3 days of
patient and SO.
“Nabudlayan filtration as evidenced nursing After 3 days of
interventions the Monitor and record nursing
ako mangihi” as by Impaired excretion of To obtain baseline
client will be able to vital signs. interventions the
verbalized by the nitrogenous products data.
secondary to Renal participate in client will be able to
parint. Review for laboratory
Failure measures to To assess for participate in
correct/compensate test for changes in contributing or measures to
Rationale: for defects renal function. causative factors. correct/compensate
Objective Data: for defects
Chronic renal Determine clients
To assess degree of
presence of failure (CRF) or chronic pattern of elimination
interference.
bipedal edema. kidney disease (CKD) is Short Term Goal
Short Term Goal Investigate pain, noting
the end result of a To investigate
Vital signs: location After 24 hours of
gradual, progressive After 24 hours of extent of
nursing intervention
Temp.: 37 C loss of kidney function. nursing intervention interference
the client will be
BP: 170/90 The loss of function may the client will be Observe for signs of To help in treating able to verbalize
mmHg be so slow that you do able to verbalize infection urinary alterations understanding of
not have symptoms understanding of condition
PR: 73 bpm. Emphasize importance To promote
until your kidneys have condition
of having good wellness.
RR: 29 cpm almost stopped
hygiene.
working.
Note condition of skin
Note: To assess level of
and mucous
hydration.
membranes, color of
urine.
Nursing Diagnosis
should be base from Determine client’s usual Enhance
(NANDA- Approved daily fluid intake commitments to
Nursing Diagnosis) promoting optimal
Establish realistic
outcomes.
activity goal with client.

Dependent:

Prescribe medication as
ordered:

- Erythropoietin
4000 u’ SC
(subcutaneous)
OD twice a week
- Ferrous sulfate+
folic acid 1
tablet TID;
Amlodipine 40
mg/1 tab OD
- Clonidine
75mcg/tab SL
prn for (BP&gt;
160/90)
- NaHCO3 gr
(grain) 2 tablets
Q8H Used to treat the
- Lactulose 30cc patient’s condition
OD at HS:
Furosemide
20mg IVTT
Q12H
- Kalimate
(Sodium
polystyrene
sulfonate 15mg
1 sachet mixed
in 30ml of water
Q12H.
- Insulin Ryzodeg
15 units SC OD
- Ketoanalogue 2
tablets TID
- Clopidogrel
75mg 1 tab OD
- Carvedilol
6.25mg 1 tab
OD
- Piperacillin +
Tazobactam
2.25gm IV q8h
ANST
- Exflem 600mg,
dissolve 1 sachet
in 50ml of water
OD.

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