ACUTE ISCHEMIC STROKE
Thrombotic strokes and Embolic
OVERVIEW
 STROKE occurs when something
blocks blood supply to part of the
brain or when a blood vessel in
the brain bursts. Stroke can cause
lasting brain damage, long-term
disability or even death.
 2 types of stoke: Ischemic Stroke
and Hemorrhagic stroke.
 Ischemic Strokes caused by
blockage of an artery.
 Hemorrhagic Stroke, these are
cause of bleeding.
 caused by a blood clot that
 ASI occurs when the blood supply
to part of the brain is interrupted
or reduce, preventing brain tissue
from getting oxygen and nutrients.
 especially on one side of the
 2 groups of Ischemic Stroke:
strokes
 Thrombotic Strokes- cause by a
blood clot that develops in the
blood vessels inside the brain.
 Embolitic Strokes- cause by a
blood clot or plaque that
develops elsewhere in the body
and then travels to one of the
blood vessels in the brain through
the blood stream.
PATHOPHYSIOLOGY
 AIS is cause by deficient blood
and oxygen supply to the brain.
 An ischemic stroke occurs when
a blood vessel that supplies the
brain becomes blocked or
"clogged" and impairs blood flow
to part of the brain. The brain
cells and tissues begin to die
within minutes from lack of
oxygen and nutrients.
 Ischemic Strokes are divided into
two groups: Thrombotic Strokes
and Embolitic Strokes.
 Thrombotic strokes- These are
develops in the blood vessels
inside the brain.
 Embolitic strokes- These are
caused by a blood clot or plaque
debris that develops elsewhere in
the body and then travels to one
of the blood vessels in the brain
through the bloodstream.
CLINICAL MANIFESTATION
 Includes: sudden numbness or
weakness in the face, arm, or leg,
body.
 The most common presenting
symptoms for ischemic stroke are
difficulty with speech and
weakness on one half of the
body.
DIAGNOSTIC TOOL
 CT Scan- usually one of the first
test used for stroke. This shows
bleeding in the brain or ato the
brain cells. CT Scan also can find
other problems that can cause
stroke symptoms.
 Brain Magnetic Resonance
Imaging (MRI) has the mosy
sensitivity and specificity and is
the best option to diagnose
Acute Ischemic stroke.
 MRI is the most accurate way to
view signs of stroke inside the
brain, but a CT scan is often faster
and more widely available.

TREATMENT AND MANAGEMENT

 can be treated with mechanical
removal of the blood clot in the
vessels called Mechanical
Thrombectomy through the help
of continuous x-ray imaging
(Fluoroscopy).
 for follow-up treatment after AIS,
px should generally take aspirin or
in certain cases, a blood thinner
medication to reduce the risk of
future strokes.
 Others take Aspirin together with
Clopidogrel for a short term
before transitioning to 1
medication.