Established Products Business

Global Established Pharma (GEP) Business. This area consists of three primary product segments: (I)
Peri-LOE products which are losing or approaching a losing position in market exclusivity; (2) legacy
established products in developed markets that have lost market exclusivity and those with growth
opportunities; and (3) emerging market products with growth opportunities such as organic initiatives,
partnerships, product enhancements, sterile injectables, and biosimilars. Examples of established
products include Celebrex, EpiPen, Zoloft, and Lypitor.