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Sports and Recreation Activity of Ankle

Arthritis Patients Before and After


Total Ankle Replacement
Victor Valderrabano,*†‡ MD, Geert Pagenstert,‡ MD, Monika Horisberger,‡
Markus Knupp,‡ MD, and Beat Hintermann,‡ MD

From the Human Performance Laboratory & Orthopaedic Department, University of Calgary,

Calgary, Canada, and the Orthopaedic Department, University Hospital of Basel,
University of Basel, Basel, Switzerland

Background: Total ankle replacement is a possible treatment for ankle arthritis; however, participation in sports after this
procedure has not yet been analyzed.
Hypotheses: There is a significant increase of sports activity after total ankle replacement in patients with arthritis. There is a
significant correlation between sports activity and American Orthopaedic Foot and Ankle Society hindfoot score in patients after
total ankle replacement.
Study Design: Case series; Level of evidence, 4.
Methods: A clinical evaluation was performed preoperatively and at follow-up after total ankle replacement in 147 patients
(152 ankles) with ankle arthritis (mean age, 59.6 years; range, 28-86 years). Ankle arthritis origin, patient satisfaction, range of
motion, American Orthopaedic Foot and Ankle Society hindfoot score, radiologic assessment, and rate, level, and type of sports
activity were documented at both evaluations. The mean follow-up was 2.8 years (range, 2-4 years).
Results: Preoperative diagnosis was posttraumatic osteoarthritis in 115 cases (76%). At total ankle replacement follow-up,
excellent and good outcomes were reported in 126 cases (83%); 105 cases (69%) were pain free. The mean range of motion pre-
operatively was 21° (range, 0°-45°); after total ankle replacement, it was 35° (range, 10°-55°; P < .05). The preoperative American
Orthopaedic Foot and Ankle Society score was 36 points; after total ankle replacement, it was 84 points (P < .001). Before
surgery, 36% of the patients were active in sports; after surgery, this percentage rose to 56% (P < .001). After total ankle replace-
ment, sports-active patients showed a significantly higher hindfoot score than did patients not active in sports: 88 versus
79 points (P < .001). The 3 most frequent sports activities were hiking, biking, and swimming.
Conclusion: There was a significant increase of sports activity by treating ankle arthritis patients with total ankle replacement.
Sports-active total ankle replacement patients showed better functional results than did inactive ones.
Keywords: sports activity; ankle; arthritis; osteoarthritis; total ankle replacement (TAR)

Sports activity determines our general state of health and prevalence of arthritis
1,4,6,14
have led to a remarkably high
represents a relevant part of our social life. This is especially and continuously increasing number of implanted total joint
true for the aging population, which has a strong desire to replacements yearly (541 245 hip and knee replacements in
remain active in sports. The increasing life expectancy (mean 1999 in the United States11). For sports medicine patients,
life expectancy in the United States in 2000 was 76.9 years2; the ability to take part in sport has been shown to correlate
in 2002, it was 77.3 years3) and the increasing incidence and with satisfaction and outcome of the performed surgery.8,23 In
the past few decades, the outcomes of total joint replace-
ments have reached a high level of satisfaction and good
*Address correspondence to Victor Valderrabano, MD, Human
Performance Laboratory & Orthopaedic Department, University of Calgary, long-term results because of improved tribology, biomechan-
2500 University Drive NW, Calgary, Alberta T2N 1N4, Canada (e-mail: ical designs, surgical techniques, and rehabilitation. The abil-
v.valderrabano@kin.ucalgary.ca). ity to return to sports and the level of sports activity after
No potential conflict of interest declared. joint replacement also have high satisfaction results.17,19 The
The American Journal of Sports Medicine, Vol. 34, No. 6
improvement of pain, function, and life quality after total
DOI: 10.1177/0363546505284189 joint replacement allows patients to increase their personal
© 2006 American Orthopaedic Society for Sports Medicine physical activities and participation in sports.19,22

993
994 Valderrabano et al The American Journal of Sports Medicine

Most of the reports in the literature on patients returning to was based on the following scale: excellent, good, moderate,
sports after total joint replacement are based on analysis of and none. Range of motion (ROM) was measured with a
patients after total hip replacement (THR) and total knee goniometer (in degrees) with the patient in a sitting position
replacement (TKR). The rate of participation in sports varies for plantar flexion and dorsiflexion and as a percentage
between 29% and 56% after THR9,13,20,24 and between 34% and either of the uninvolved contralateral leg or of the healthy
77% after TKR.5,13 A few years ago, the Hip Society and Knee population for inversion/eversion, as required for the
Society outlined their consensus recommendations on athletic AOFAS hindfoot score.16 Hindfoot alignment was measured
activity after THR and TKR and classified several sports activ- with a goniometer with the patient in a standing position
ities as follows: “recommended/allowed,” “allowed with experi- and defined as follows: normal, 0° to 10°; valgus, >10°; or
ence,” “not recommended,” and “no conclusion.”10 Typically varus, <0°. The AOFAS hindfoot score,16 which includes
allowed sports are biking, swimming, walking, golfing, and pain, function, and alignment evaluations, was used to
others. Sports allowed with experience are hiking, low-impact assess overall clinical-functional level (minimum score of
aerobics, horseback riding, and cross-country skiing. Sports 0 points, maximum score of 100 points). As standard diag-
that are not recommended include basketball, baseball, soccer, nostics in TAR patients, the patients were radiologically
football, jogging, squash, volleyball, and others. No conclusion examined preoperatively and at follow-up using standard
has been published for downhill skiing, weight lifting, and oth- weightbearing radiographs in 2 planes (AP, lateral). This
ers. In general, patients with total joint replacements are study used the radiologic analysis methods of loosening and
encouraged to participate in low-impact, low-demanding migration as reported by Hintermann et al.12
sports and to avoid high-impact, high-demanding sports.11 Each patient’s sports activity level was documented pre-
In contrast to THR and TKR, to the knowledge of the operatively and at TAR follow-up using the following scale:
authors, there are no reports in the literature on precise grade 0, none; grade 1, moderate; grade 2, normal; grade 3,
analysis or recommendations of participation in sports after high; and grade 4, elite (Table 1). All types of sports acti-
total ankle replacement (TAR). Therefore, the purpose vities reported by the patients were documented.
of the present prospective study was to determine the rate, All subjects gave informed consent to participate in the
level, and type of sports activities possible with ankle study. The study was carried out in accordance with the
arthritis and after TAR, as well as to correlate sports level World Medical Association Declaration of Helsinki.
and outcome after TAR. The hypotheses of the present Statistical analysis of the data was performed with
study were as follows: (1) There is a significant increase of SPSS(r) software (version 12.0, SPSS Science Inc, Chicago,
sports activity in patients with end-stage ankle arthritis Ill) to perform the paired Student t test, McNemar test,
after TAR, and (2) there is a significant correlation between and Pearson correlation analysis (r). The significance level
sports activity level and the American Orthopaedic Foot and was set at P < .05.
Ankle Society (AOFAS) hindfoot score in patients with TAR.

RESULTS
METHODS
Based on the patients’ histories, the preoperative diagnosis
In this study, 147 consecutive patients (77 women and was posttraumatic osteoarthritis in 115 cases (76%), pri-
70 men, representing 152 ankle cases; mean age, 59.6 years; mary osteoarthrosis in 21 cases (13%), and systemic arthri-
range, 28-86 years) suffering from end-stage ankle arthri- tis in 16 cases (11%).
tis and treated with a 3-component uncemented TAR The patients rated their satisfaction with the TAR as
(HINTEGRA, Newdeal SA, Lyon, France) were prospec- excellent in 49 cases (32%), good in 77 cases (51%), moder-
tively analyzed (ie, preoperatively under the condition of ate in 17 cases (11%), and poor in 9 cases (6%). Although the
ankle arthritis and at follow-up of the implanted TAR) mean VAS pain score preoperatively was 6.9 points (range,
(Figure 1). The inclusion criterion was symptomatic end- 3-10 points), at follow-up after TAR, 105 ankles (69%) were
stage ankle arthritis with fulfillment of general TAR completely pain free (VAS, 0 points), and 47 (31%) suffered
indications (good bone stock, normal vascular status, no
immunosuppression, sufficient medial and lateral ankle
stability). The exclusion criteria were neuroarthropathic TABLE 1
degenerative disease (Charcot ankle), active or recent infec- Sports Frequency Score
tion, substantial avascular necrosis of the talus, severe Score Definition
benign joint hypermobility syndrome, nonreconstructable
malalignment, severe soft tissue problems around the 0 (none) No sports activity
ankle, and sensory or motor dysfunction of the foot or leg. 1 (moderate) Moderate level of sports activity in
The postoperative follow-up level was set at a minimum of leisure time, <1 h/wk
2 years, and follow-up was performed by an unbiased 2 (normal) Normal level of sports activity in leisure
observer (M. H.). The mean follow-up in this study was time, 1-5 h/wk
2.8 years (range, 2-4 years). 3 (high) High level of sports activity in leisure
time, >5 h/wk
Pain was quantified using a visual analog scale (VAS), with
4 (elite) Professional level of sports activity,
0 points representing no pain and 10 points representing elite athlete
maximal imaginable pain. The overall subjective satisfaction
Vol. 34, No. 6, 2006 Sports in Ankle Arthritis and TAR 995

Figure 1. Treatment of ankle arthritis by total ankle replacement. Patient with severe posttraumatic ankle osteoarthritis (A, B) and
implanted total ankle replacement at follow-up (C, D).
996 Valderrabano et al The American Journal of Sports Medicine

TABLE 2
Diagnosis-Dependent Analysis of AOFAS Score and Sports Activitya

AOFAS Score Sports Activity Rate Sports Activity Levelb

PRE TAR PRE TAR PRE TAR

Absolute Absolute Mean Mean


Etiology Mean Range Mean Range % No. % No. Grade Range Grade Range
c d c
Posttraumatic 38 0-74 83 28-100 40 46 58 67 0.6 0-3 1.0 0-3
osteoarthritis (n = 115)
Primary 36 0-62 86c 52-100 19 4 62d 13 0.1 0-1 0.9d 0-2
osteoarthrosis (n = 21)
Systemic 25 10-52 89c 45-100 31 5 31 5 0.2 0-1 0.3 0-2
arthritis (n = 16)
Total (N = 152) 36 10-74 84c 28-100 36 55 56c 85 0.5 0-3 0.9c 0-3
a
AOFAS score, hindfoot score of the American Orthopaedic Foot and Ankle Society; PRE, preoperative arthritic condition; TAR, total ankle
replacement condition.
b
See Table 1.
c
Statistically significantly different from preoperative condition, P < .001.
d
Statistically significantly different from preoperative condition, P < .05.

TABLE 3 TABLE 4
Sports Activity Level and Rate List of Reported Sports Activities

Preoperative Total Ankle Preoperative Total Ankle


Arthritic Conditionb Replacementc Arthritic Conditiona Replacementb

Sports Activity Absolute No. Absolute No. Type of Sports Absolute No. Absolute No.
Level Gradea % of Patients % of Patients Activity % of Patients % of Patients

0 64 97 44 67 Hiking 26 14 53 45c
1 24 37 27 41 Biking 44 24 46 39d
2 9 14 22 34 Swimming 40 22 34 29
3 3 4 7 10 Aerobics 18 10 12 10
4 0 0 0 0 Downhill 11 6 8 7
skiing
Sports activity 36 55 56 85d Golfing 4 2 6 5
rate Horseback 4 2 2 2
riding
a
See Table 1. Tennis 4 2 1 1
b
Sports activity level with ankle arthritis preoperatively Bowling 0 0 1 1
(N = 152). Jogging 0 0 1 1
c
Sports activity level with total ankle replacement at follow-up Waterskiing 0 0 1 1
(N = 152).
d a
Paired Student t test for all levels shows statistically significant Sports activities reported with ankle arthritis preoperatively.
b
difference, P < .001. Sports activities reported with total ankle replacement at
follow-up.
c
Statistically significantly different from ankle arthritis condition,
P < .001.
moderate pain (mean VAS, 2.4 points; range, 1-5 points; d
Statistically significantly different from ankle arthritis condition,
P < .001). The mean dorsiflexion/plantar flexion ROM pre- P < .05.
operatively was 21° (range, 0°-45°) and at final follow-up
was 35° (range, 10°-55°; P = .04). The mean preoperative
AOFAS hindfoot score was 36 points (range, 10-74 points) 20 percentage points; P < .001) (Tables 2 and 3). A significant
and at follow-up was 84 points (range, 28-100 points), rate increase was seen in the posttraumatic osteoarthritis
which was significantly higher (P < .001) (Table 2). The sys- and primary osteoarthrosis group (P < .003 and P < .012,
temic ankle arthritis group after TAR averaged 89 points respectively) (Table 2). The systemic arthritis group did
(range, 45-100 points), which was the highest AOFAS hind- not contribute to the sports activity rate increase (differ-
foot score (Table 2). ence before and after TAR, 31%; P = 1). The overall sports
Preoperatively, the sports activity rate was 36% (55 activity level distribution after TAR was significantly dif-
cases); after TAR, it was 56% (85 cases; overall increase of ferent from the one at the preoperative arthritic condition
Vol. 34, No. 6, 2006 Sports in Ankle Arthritis and TAR 997

Ankle Arthritis Total Ankle Replacement


Sports-Active
Sports-Active n = 42 (76%)
AOFAS Hindfoot Score: 92 (66-100)
n = 55 (36%)
Sports-Inactive
AOFAS Hindfoot Score: 39 (16-74)
n = 13 (24%)
AOFAS Hindfoot Score: 81 (37-92)*
Sports-Active
Sports-Inactive n = 43 (44%)
AOFAS Hindfoot Score: 84 (56-100)
n = 97 (64%) Sports-Inactive
AOFAS Hindfoot Score: 34 (10-72)a
n = 54 (56%)
AOFAS Hindfoot Score: 78 (28-100)**

Figure 2. Sports activity flowchart. aNo statistically significant difference to sports-active ankle arthritis patients (P = .12).
*Statistically significant difference to sports-active total ankle replacement patients (from group of sports-active ankle arthritis
patients; P < .05). **Statistically significant difference to sports-active total ankle replacement patients (from group of sports-
inactive ankle arthritis patients; P < .001). AOFAS, American Orthopaedic Foot and Ankle Society.

(P < .001) (Table 3). After TAR, there was a significant from hemophilic arthritis. Nine of these 13 ankles had a
increase of sports-active cases in grades 1 to 3 (P < .001). primary loosening of the components that had to be conse-
None of the patients reported sports activity grade 4/elite quently exchanged. One patient suffered from a fibulotalar
either before or after TAR. impingement, 2 patients from ankle joint stiffness, and
Among patients who were active in sports preoperatively, 1 patient from an inlay dislocation due to a varus malalign-
76% of the cases (n = 42) maintained their sports activity ment. In all revision cases, the sports activity level had
after TAR implantation (P = .01) (Figure 2). Twenty-four per- been 0 after primary TAR implantation. All 13 cases under-
cent of the sports-active arthritis patients lost their sports went successful revision surgery, and none had to be con-
activity after TAR implantation because of continued pain verted to an ankle arthrodesis. Of these 13 revised cases,
(VAS, 4; range, 3-5) and had decreased AOFAS hindfoot at follow-up, 7 patients did not perform sports (grade 0),
scores (81 points; range, 37-92 points). In the group that was 5 patients performed grade 1/moderate sports, and 1 patient
not active in sports preoperatively, 44% of the cases (n = 43) performed grade 2/normal sports.
regained a sports activity (such as swimming, biking, hiking) On radiographs at recent follow-up, the tibial component
after TAR implantation (P < .001) (Figure 2). The new was stable in all cases, showing no progressive tilting or
regained sports activity levels were grade 1/moderate in 23 migration of the component since primary or revision surgery.
cases, grade 2/normal in 18 cases, and grade 3/high in 2 cases. As the bone-component interface of the talar component can-
The most frequently reported sports activities preopera- not be seen radiologically, loosening can only be assumed from
tively were, in descending order, biking (43.6%), swimming migration of the component. This was observed in 3 ankles;
(40.0%), hiking (25.5%), aerobics (18.2%), and downhill ski- these patients reported no sports activity and only moderate
ing (10.9%). Golfing, horseback riding, and tennis were pain. Eleven ankles (7%) had evidence of heterotopic
performed equally (3.6%) (Table 4). The most frequently periarticular bone formation that did not correlate with
reported sports activities after TAR were, in descending the sports activity level after TAR (r = .2, P = .62).
order, hiking (52.8%), biking (45.9%), swimming (34.1%),
aerobics (11.8%), downhill skiing (8.2%), golfing (5.9%),
and horseback riding (2.4%). Tennis, bowling, jogging, and DISCUSSION
waterskiing were performed equally (1.2%) (Table 4).
Statistical analysis between preoperative and postopera- The principal findings of this study were that TAR
tive situations showed a significant difference for only hik- increased the sports activity rate in ankle arthritis patients
ing (P < .001) and biking (P = .02). and that patients active in sports after TAR showed a
Comparing sports activity and AOFAS hindfoot score, higher functional AOFAS hindfoot score than did patients
there was no significant correlation between sports activ- who were not active in sports.
ity level and AOFAS hindfoot score preoperatively (r = .1, The increased success with arthroplasty of joints such as
P = .13), but a significant correlation was seen after TAR the knee or hip,5,10 along with concerns about the long-term
(r = .4, P < .001). Overall, sports-active TAR patients outcomes after ankle arthrodesis,7,21 has created renewed
showed a significantly higher AOFAS hindfoot score than interest in total ankle arthroplasty during the past
did patients who were not active in sports: 88 points versus decade.12,18,25,26 New 2- and 3-component TAR systems have
79 points (P < .001). been designed with attention to the reproduction of normal
Thirteen ankles (9%) required a revision of the TAR at the ankle function, normal joint biomechanics, physiologic liga-
time of follow-up. Twelve of these 13 ankles had an origin of ment stability, and correct mechanical alignment. Recent
posttraumatic ankle osteoarthritis, and 1 patient suffered total ankle prostheses also include porous-coating and
998 Valderrabano et al The American Journal of Sports Medicine

TABLE 5
Guidelines for Sports Activity After Total Ankle Replacement (TAR)

General Guidelinesa

1. In general and on a long-term basis, after TAR, patients must be aware of the possibility of accelerated polyethylene wear,
loosening, or revision surgery due to inappropriate sports activity.
2. Before sports activity, patients with a TAR should be free of any complications and have undergone a physical therapy
rehabilitation program.
3. The TAR must show a radiologically concluded osteointegration and no signs of loosening or migration.
4. Before sports activity, patients with a TAR must consult their treating surgeon to discuss the individually allowed/recommended
sport and possibly required supporting orthoses.
5. In general, high-impact and stop-and-go sports should be avoided.
6. Patients with pain during sports activity must consult their treating surgeon.

Allowed With Experience/Caution


Allowed and Appropriate Equipment Not Recommended

Stationary biking; ballroom dancing; Low-impact aerobics; road biking; bowling; High-impact aerobics; baseball; basketball;
bowling; golfing; swimming; walking low-impact gymnastics; hiking; rowing; cross-country skiing; football; gymnastics; handball;
downhill skiing; doubles tennis hockey/ice skating; horseback riding; inline skating;
jogging; lacrosse; squash; rock climbing; soccer;
singles tennis; volleyball; waterskiing; and others
a
Guidelines are based on Healy et al,10 Vertullo and Nunley,27 the results of the present study, and the authors’ experience.

anatomical surfaces that allow for biological fixation and was the most reported sports activity after TAR (Table 4),
reduced amount of bone resection necessary for implanta- with a 53% higher rate than the one described by Dubs et al9
tion.12 Similar to THR and TKR, the positive results and in their study on THR (41%). When discussing the steady
increased survivorship after TAR12,18,25,26 have encouraged state of the downhill skiing rate in the arthritic and TAR
patients to take this treatment into consideration for their condition, one has to take into account the degree of popu-
painful end-stage ankle arthritis, allowing them to reach a larity of this sport in our country. Patients who performed
better functional level or even to take part in sports. downhill skiing after TAR often reported that they felt quite
To our knowledge, at the present time there are no stable and supported in their hard ski boots while skiing.
studies in the literature specifically addressing the rate After TAR, patients who returned to sports had a signifi-
of sports activity in a large series of end-stage ankle arthri- cantly higher clinical-functional AOFAS hindfoot score
tis patients. Not surprisingly, in the present study, 64% of than did patients who did not engage in sports. However,
the patients did not perform any sports preoperatively. The the exact relationship between sports activity level and
sports activity rate of 36% in our patients with ankle arthri- AOFAS hindfoot score is still unclear. The patients could
tis was mainly represented by the moderate sports level be returning to sports because they have higher AOFAS
grade 1 (Table 3). Driven by their subjective symptoms hindfoot scores, or they could have higher AOFAS scores
(such as pain, depression, and others) and their joint patho- because they are active in sports. Whether sports activity
biomechanics (such as reduced ROM, limp, reduced walking has a protective or harmful effect on long-term outcome
distance, and others), ankle arthritis patients tended to after TAR was not answered in the present study. However,
perform mainly low-impact sport activities, such as biking we did show that patients who reported sports activity in
and swimming (Table 4), to avoid possible abnormal ground the preoperative arthritic state had a tendency to be active
reaction forces and, therefore, pain-inducing joint reaction in sports after the TAR procedure (Figure 2). Furthermore,
forces. this study showed that at this length of follow-up, there is
Patients’ return to sports has been reported for not a negative relationship between revision rate and
THR9,13,20,24 and TKR,5,13 but no reports exist on how many sports activity. As do others, we believe that low-impact
patients can return to sports after TAR. In the literature, sports activity might be beneficial for the bone-implant
the sports activity rate after THR and TKR varies between interface by encouraging bone ingrowth as long as the
29% and 77%, of which an overall THR-TKR mean rate of forces are below an as yet unidentified threshold.5,9 Sports
49% can be calculated.5,9,13,20,24 The rate of sports activity activity might also help to reduce muscle atrophy, which is
after TAR in the present study was 56% and is therefore often seen preoperatively in patients with ankle arthritis,
within the reported rate range and close to the calculated and help to enhance the lower leg muscular performance.
overall mean rate for THR and TKR. Compared with the Thus, it might reduce the dangerous peaks of the resulting
preoperative arthritic state,TAR significantly increased the joint reaction forces during locomotion.
overall sports activity rate in our cohort by 20%. The high- Guidelines for return to sports after TAR are not available
est absolute increase was seen in the sports levels grade in the literature; therefore, the authors came up with a recom-
2/normal and grade 3/high (Table 3). Remarkably, hiking mendation for sports activity after TAR (Table 5) based on
Vol. 34, No. 6, 2006 Sports in Ankle Arthritis and TAR 999

the recommendations of the Hip Society and Knee Society for 2. Arias E. United States life tables, 2000. Natl Vital Stat Rep. 2002;51:
sports activity after THR/TKR as reported by Healy et al,10 1-38.
3. Arias E. United States life tables, 2002. Natl Vital Stat Rep. 2004;53:
on the guidelines of sports activity after foot and ankle
1-38.
arthrodeses reported by Vertullo and Nunley,27 and on the 4. Baumhauer JF, Alosa DM, Renstrom AF, Trevino S, Beynnon B. A
results of the present study and our own long-standing expe- prospective study of ankle injury risk factors. Am J Sports Med. 1995;
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loosening, migration, accelerated polyethylene wear, or even 7. Coester LM, Saltzman CL, Leupold J, Pontarelli W. Long-term results
component breakage.5,15,19 Despite the herewith-improved following ankle arthrodesis for post-traumatic arthritis. J Bone Joint
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(Table 1) represents a sports frequency score and does not plasty. Clin Orthop Relat Res. 2000;380:65-71.
12. Hintermann B, Valderrabano V, Dereymaeker G, Dick W. The HINTEGRA
take into consideration the variable physical activity
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The authors thank all staff members of the Orthopaedic
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Academy of Orthopaedic Surgeons Congress; March 10-12, 2004;
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